6HTK
 
 | | X-ray structure of the tryptophan lyase NosL in complex with (R)-(+)-indoline-2-carboxylate | | 分子名称: | 1H-indole-2-carboxylic acid, 3-methyl-2-indolic acid synthase, 5'-DEOXYADENOSINE, ... | | 著者 | Amara, P, Mouesca, J.M, Bella, M, Martin, L, Saragaglia, C, Gambarelli, S, Nicolet, Y. | | 登録日 | 2018-10-04 | | 公開日 | 2018-11-21 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Radical S-Adenosyl-l-methionine Tryptophan Lyase (NosL): How the Protein Controls the Carboxyl Radical •CO2-Migration.
J.Am.Chem.Soc., 140, 2018
|
|
6HTO
 | | Tryptophan lyase 'empty state' | | 分子名称: | 3-methyl-2-indolic acid synthase, 5'-DEOXYADENOSINE, CHLORIDE ION, ... | | 著者 | Amara, P, Mouesca, J.M, Bella, M, Martin, L, Saragaglia, C, Gambarelli, S, Nicolet, Y. | | 登録日 | 2018-10-04 | | 公開日 | 2018-11-21 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | | 主引用文献 | Radical S-Adenosyl-l-methionine Tryptophan Lyase (NosL): How the Protein Controls the Carboxyl Radical •CO2-Migration.
J.Am.Chem.Soc., 140, 2018
|
|
7PD2
 | | Crystal structure of the substrate-free radical SAM tyrosine lyase ThiH (2-iminoacetate synthase) from Thermosinus carboxydivorans | | 分子名称: | 5'-DEOXYADENOSINE, GLYCEROL, IRON/SULFUR CLUSTER, ... | | 著者 | Amara, P, Saragaglia, C, Mouesca, J.-M, Martin, L, Nicolet, Y. | | 登録日 | 2021-08-04 | | 公開日 | 2022-05-11 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.99 Å) | | 主引用文献 | L-tyrosine-bound ThiH structure reveals C-C bond break differences within radical SAM aromatic amino acid lyases.
Nat Commun, 13, 2022
|
|
7PD1
 | | Crystal structure of the L-tyrosine-bound radical SAM tyrosine lyase ThiH (2-iminoacetate synthase) from Thermosinus carboxydivorans | | 分子名称: | 5'-DEOXYADENOSINE, BROMIDE ION, GLYCEROL, ... | | 著者 | Amara, P, Saragaglia, C, Mouesca, J.-M, Martin, L, Nicolet, Y. | | 登録日 | 2021-08-04 | | 公開日 | 2022-05-11 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.27 Å) | | 主引用文献 | L-tyrosine-bound ThiH structure reveals C-C bond break differences within radical SAM aromatic amino acid lyases.
Nat Commun, 13, 2022
|
|
6HTM
 | | X-ray structure of the tryptophan lyase NosL in complex with bound tryptamin | | 分子名称: | 2-(1H-INDOL-3-YL)ETHANAMINE, 3-methyl-2-indolic acid synthase, 5'-DEOXYADENOSINE, ... | | 著者 | Amara, P, Mouesca, J.M, Bella, M, Saragaglia, C, Gambarelli, S, Nicolet, Y. | | 登録日 | 2018-10-04 | | 公開日 | 2018-11-21 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Radical S-Adenosyl-l-methionine Tryptophan Lyase (NosL): How the Protein Controls the Carboxyl Radical •CO2-Migration.
J.Am.Chem.Soc., 140, 2018
|
|
9CPL
 | |
8S5F
 | | Crystal structure of the HExxH domain of ChlBHExxH a novel alpha-ketoglutarate dependent oxygenase | | 分子名称: | ChlH from Chlorogloeopsis sp., PHOSPHATE ION | | 著者 | de la Mora, E, Amara, P, Usclat, A, Morishita, Y, Morinaka, B, Nicolet, Y. | | 登録日 | 2024-02-23 | | 公開日 | 2024-10-02 | | 実験手法 | X-RAY DIFFRACTION (2.797 Å) | | 主引用文献 | Fused radical SAM and alpha KG-HExxH domain proteins contain a distinct structural fold and catalyse cyclophane formation and beta-hydroxylation.
Nat.Chem., 2024
|
|
7BI7
 | | An Unexpected P-Cluster like Intermediate En Route to the Nitrogenase FeMo-co | | 分子名称: | FE(8)-S(7) CLUSTER, FeMo cofactor biosynthesis protein NifB, HYDROSULFURIC ACID, ... | | 著者 | Jenner, L.P, Cherrier, M.V, Amara, P, Rubio, L.M, Nicolet, Y. | | 登録日 | 2021-01-12 | | 公開日 | 2021-03-10 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | An unexpected P-cluster like intermediate en route to the nitrogenase FeMo-co.
Chem Sci, 12, 2021
|
|
4R34
 | | X-ray structure of the tryptophan lyase NosL with Tryptophan, 5'-deoxyadenosine and methionine bound | | 分子名称: | 5'-DEOXYADENOSINE, BROMIDE ION, GLYCEROL, ... | | 著者 | Nicolet, Y, Zeppieri, L, Amara, P, Fontecilla-Camps, J.-C. | | 登録日 | 2014-08-14 | | 公開日 | 2014-09-17 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Crystal Structure of Tryptophan Lyase (NosL): Evidence for Radical Formation at the Amino Group of Tryptophan.
Angew.Chem.Int.Ed.Engl., 53, 2014
|
|
4R33
 | | X-ray structure of the tryptophan lyase NosL with Tryptophan and S-adenosyl-L-homocysteine bound | | 分子名称: | CHLORIDE ION, GLYCEROL, IRON/SULFUR CLUSTER, ... | | 著者 | Nicolet, Y, Zeppieri, L, Amara, P, Fontecilla-Camps, J.-C. | | 登録日 | 2014-08-14 | | 公開日 | 2014-09-17 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.78 Å) | | 主引用文献 | Crystal Structure of Tryptophan Lyase (NosL): Evidence for Radical Formation at the Amino Group of Tryptophan.
Angew.Chem.Int.Ed.Engl., 53, 2014
|
|
4RTB
 | | X-ray structure of the FeFe-hydrogenase maturase HydG from Carboxydothermus hydrogenoformans | | 分子名称: | CHLORIDE ION, HydG protein, IRON/SULFUR CLUSTER, ... | | 著者 | Nicolet, Y, Pagnier, A, Zeppieri, L, Martin, L, Amara, P, Fontecilla-Camps, J.C. | | 登録日 | 2014-11-14 | | 公開日 | 2015-01-28 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.79 Å) | | 主引用文献 | Crystal Structure of HydG from Carboxydothermus hydrogenoformans: A Trifunctional [FeFe]-Hydrogenase Maturase.
Chembiochem, 16, 2015
|
|
4DCX
 | | X-ray structure of NikA in complex with Fe(1R,2R)-N,N'-Bis(2-pyridylmethyl)-N,N'-dicarboxymethyl-1,2-cyclohexanediamine | | 分子名称: | ACETATE ION, GLYCEROL, Nickel-binding periplasmic protein, ... | | 著者 | Cherrier, M.V, Girgenti, E, Amara, P, Iannello, M, Marchi-Delapierre, C, Fontecilla-Camps, J.C, Menage, S, Cavazza, C. | | 登録日 | 2012-01-18 | | 公開日 | 2012-05-09 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | The structure of the periplasmic nickel-binding protein NikA provides insights for artificial metalloenzyme design.
J.Biol.Inorg.Chem., 17, 2012
|
|
4DCY
 | | X-ray structure of NikA in complex with Fe(1S,2S)-N,N-kappa-Bis(2-pyridylmethyl)-N-carboxymethyl-N-kappa-methyl-1,2-cyclohexanediamine | | 分子名称: | ACETATE ION, GLYCEROL, Nickel-binding periplasmic protein, ... | | 著者 | Cherrier, M.V, Girgenti, E, Amara, P, Iannello, M, Marchi-Delapierre, C, Fontecilla-Camps, J.C, Menage, S, Cavazza, C. | | 登録日 | 2012-01-18 | | 公開日 | 2012-05-09 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | The structure of the periplasmic nickel-binding protein NikA provides insights for artificial metalloenzyme design.
J.Biol.Inorg.Chem., 17, 2012
|
|
3IIZ
 | | X-ray structure of the FeFe-hydrogenase maturase HydE from T. maritima in complex with S-adenosyl-L-methionine | | 分子名称: | 3-[(3-CHOLAMIDOPROPYL)DIMETHYLAMMONIO]-1-PROPANESULFONATE, Biotin synthetase, putative, ... | | 著者 | Nicolet, Y, Amara, P, Mouesca, J.M, Fontecilla-Camps, J.C. | | 登録日 | 2009-08-03 | | 公開日 | 2009-09-22 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.62 Å) | | 主引用文献 | Unexpected electron transfer mechanism upon AdoMet cleavage in radical SAM proteins
Proc.Natl.Acad.Sci.USA, 2009
|
|
3IIX
 | | X-ray structure of the FeFe-hydrogenase maturase HydE from T. maritima in complex with methionine and 5'deoxyadenosine | | 分子名称: | 3-[(3-CHOLAMIDOPROPYL)DIMETHYLAMMONIO]-1-PROPANESULFONATE, 5'-DEOXYADENOSINE, CARBONATE ION, ... | | 著者 | Nicolet, Y, Amara, P, Mouesca, J.M, Fontecilla-Camps, J.C. | | 登録日 | 2009-08-03 | | 公開日 | 2009-09-22 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.25 Å) | | 主引用文献 | Unexpected electron transfer mechanism upon AdoMet cleavage in radical SAM proteins
Proc.Natl.Acad.Sci.USA, 2009
|
|
3CIX
 | | X-RAY structure of the [FeFe]-hydrogenase maturase HydE from thermotoga maritima in complex with thiocyanate | | 分子名称: | 3-[(3-CHOLAMIDOPROPYL)DIMETHYLAMMONIO]-1-PROPANESULFONATE, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... | | 著者 | Nicolet, Y, Ruback, J.K, Posewitz, M.C, Amara, P, Mathevon, C, Atta, M, Fontecave, M, Fontecilla-Camps, J.C. | | 登録日 | 2008-03-12 | | 公開日 | 2008-04-08 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | X-ray Structure of the [FeFe]-Hydrogenase Maturase HydE from Thermotoga maritima
J.Biol.Chem., 283, 2008
|
|
3CIW
 | | X-RAY structure of the [FeFe]-hydrogenase maturase HydE from thermotoga maritima | | 分子名称: | 3-[(3-CHOLAMIDOPROPYL)DIMETHYLAMMONIO]-1-PROPANESULFONATE, CHLORIDE ION, FeFe-Hydrogenase maturase, ... | | 著者 | Nicolet, Y, Ruback, J.K, Posewitz, M.C, Amara, P, Mathevon, C, Atta, M, Fontecave, M, Fontecilla-Camps, J.C. | | 登録日 | 2008-03-12 | | 公開日 | 2008-04-08 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | | 主引用文献 | X-ray Structure of the [FeFe]-Hydrogenase Maturase HydE from Thermotoga maritima
J.Biol.Chem., 283, 2008
|
|
4EB7
 | | A. fulgidus IscS-IscU complex structure | | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, FE2/S2 (INORGANIC) CLUSTER, GLYCEROL, ... | | 著者 | Marinoni, E.N, de Oliveira, J.S, Nicolet, Y, Raulfs, E.C, Amara, P, Dean, D.R, Fontecilla-Camps, J.C. | | 登録日 | 2012-03-23 | | 公開日 | 2012-05-02 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | | 主引用文献 | (IscS-IscU)2 complex structures provide insights into Fe2S2 biogenesis and transfer.
Angew.Chem.Int.Ed.Engl., 51, 2012
|
|
4EB5
 | | A. fulgidus IscS-IscU complex structure | | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, FE2/S2 (INORGANIC) CLUSTER, GLYCEROL, ... | | 著者 | Marinoni, E.N, de Oliveira, J.S, Nicolet, Y, Raulfs, E.C, Amara, P, Dean, D.R, Fontecilla-Camps, J.C. | | 登録日 | 2012-03-23 | | 公開日 | 2012-05-02 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.53 Å) | | 主引用文献 | (IscS-IscU)2 complex structures provide insights into Fe2S2 biogenesis and transfer.
Angew.Chem.Int.Ed.Engl., 51, 2012
|
|
4I9D
 | | X-ray structure of NikA in complex with Fe-N,N'-Bis(2-pyridylmethyl)-N-carboxymethyl-N'-methyl | | 分子名称: | ACETATE ION, GLYCEROL, Nickel-binding periplasmic protein, ... | | 著者 | Cherrier, M.V, Amara, P, Iannello, M, Cavazza, C. | | 登録日 | 2012-12-05 | | 公開日 | 2013-04-17 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | An artificial oxygenase built from scratch: substrate binding site identified using a docking approach.
Angew.Chem.Int.Ed.Engl., 52, 2013
|
|
6FD2
 | | Radical SAM 1,2-diol dehydratase AprD4 in complex with its substrate paromamine | | 分子名称: | 5'-DEOXYADENOSINE, IRON/SULFUR CLUSTER, METHIONINE, ... | | 著者 | Liu, W.Q, Amara, P, Mouesca, J.M, Ji, X, Renoux, O, Martin, L, Zhang, C, Zhang, Q, Nicolet, Y. | | 登録日 | 2017-12-21 | | 公開日 | 2018-01-17 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | | 主引用文献 | 1,2-Diol Dehydration by the Radical SAM Enzyme AprD4: A Matter of Proton Circulation and Substrate Flexibility.
J. Am. Chem. Soc., 140, 2018
|
|
4P3X
 | | Structure of the Fe4S4 quinolinate synthase NadA from Thermotoga maritima | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, IRON/SULFUR CLUSTER, Quinolinate synthase A, ... | | 著者 | Cherrier, M.V, Chan, A, Darnault, C, Reichmann, D, Amara, P, Ollagnier de Choudens, S, Fontecilla-Camps, J.C. | | 登録日 | 2014-03-10 | | 公開日 | 2014-04-02 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | The crystal structure of Fe4S4 quinolinate synthase unravels an enzymatic dehydration mechanism that uses tyrosine and a hydrolase-type triad.
J.Am.Chem.Soc., 136, 2014
|
|
6H8T
 | | Crystal structure of Papain modify by achiral Ru(II)complex | | 分子名称: | ACETATE ION, CHLORIDE ION, Papain, ... | | 著者 | Cherrier, M.V, Amara, P, Talbi, B, Salmin, M, Fontecilla-Camps, J.C. | | 登録日 | 2018-08-03 | | 公開日 | 2018-09-12 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Crystallographic evidence for unexpected selective tyrosine hydroxylations in an aerated achiral Ru-papain conjugate.
Metallomics, 10, 2018
|
|
5FF0
 | | HydE from T. maritima in complex with S-adenosyl-L-cysteine and methionine | | 分子名称: | 3-[(3-CHOLAMIDOPROPYL)DIMETHYLAMMONIO]-1-PROPANESULFONATE, CHLORIDE ION, Fe4-Se4 cluster, ... | | 著者 | Rohac, R, Amara, P, Benjdia, A, Martin, L, Ruffie, P, Favier, A, Berteau, O, Mouesca, J.M, Fontecilla-Camps, J.C, Nicolet, Y. | | 登録日 | 2015-12-17 | | 公開日 | 2016-04-06 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.49 Å) | | 主引用文献 | Carbon-sulfur bond-forming reaction catalysed by the radical SAM enzyme HydE.
Nat.Chem., 8, 2016
|
|
5FEP
 | | HydE from T. maritima in complex with (2R,4R)-MeTDA | | 分子名称: | (2R,4R)-2-methyl-1,3-thiazolidine-2,4-dicarboxylic acid, 3-[(3-CHOLAMIDOPROPYL)DIMETHYLAMMONIO]-1-PROPANESULFONATE, CHLORIDE ION, ... | | 著者 | Rohac, R, Amara, P, Benjdia, A, Martin, L, Ruffie, P, Favier, A, Berteau, O, Mouesca, J.M, Fontecilla-Camps, J.C, Nicolet, Y. | | 登録日 | 2015-12-17 | | 公開日 | 2016-04-06 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | | 主引用文献 | Carbon-sulfur bond-forming reaction catalysed by the radical SAM enzyme HydE.
Nat.Chem., 8, 2016
|
|
