6I2P
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![BU of 6i2p by Molmil](/molmil-images/mine/6i2p) | Crystal structure of the Mycobacterium tuberculosis PknB kinase domain (L33E mutant) in complex with its substrate GarA | 分子名称: | Glycogen accumulation regulator GarA, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, ... | 著者 | Andre-Leroux, G, Hindie, V, Barilone, N, Bellinzoni, M, Alzari, P.M. | 登録日 | 2018-11-01 | 公開日 | 2019-05-22 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.37 Å) | 主引用文献 | Structural insights into the functional versatility of an FHA domain protein in mycobacterial signaling. Sci.Signal., 12, 2019
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1FBI
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6Z0F
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![BU of 6z0f by Molmil](/molmil-images/mine/6z0f) | Crystal structure of the membrane pseudokinase YukC/EssB from Bacillus subtilis T7SS | 分子名称: | ESX secretion system protein YukC | 著者 | Tassinari, M, Bellinzoni, M, Alzari, P.M, Fronzes, R, Gubellini, F. | 登録日 | 2020-05-08 | 公開日 | 2021-05-19 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.553 Å) | 主引用文献 | The Antibacterial Type VII Secretion System of Bacillus subtilis: Structure and Interactions of the Pseudokinase YukC/EssB. Mbio, 13, 2022
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7A1D
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![BU of 7a1d by Molmil](/molmil-images/mine/7a1d) | Cryo-EM map of the large glutamate dehydrogenase composed of 180 kDa subunits from Mycobacterium smegmatis (open conformation) | 分子名称: | NAD-specific glutamate dehydrogenase | 著者 | Lazaro, M, Melero, R, Huet, C, Lopez-Alonso, J.P, Delgado, S, Dodu, A, Bruch, E.M, Abriata, L.A, Alzari, P.M, Valle, M, Lisa, M.N. | 登録日 | 2020-08-12 | 公開日 | 2021-06-09 | 最終更新日 | 2024-07-10 | 実験手法 | ELECTRON MICROSCOPY (4.19 Å) | 主引用文献 | 3D architecture and structural flexibility revealed in the subfamily of large glutamate dehydrogenases by a mycobacterial enzyme. Commun Biol, 4, 2021
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7AL1
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![BU of 7al1 by Molmil](/molmil-images/mine/7al1) | Cell division protein SepF from Methanobrevibacter smithii | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Cell division protein SepF | 著者 | Sogues, A, wehenkel, A.M, Alzari, P.M. | 登録日 | 2020-10-04 | 公開日 | 2021-03-31 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | SepF is the FtsZ anchor in archaea, with features of an ancestral cell division system. Nat Commun, 12, 2021
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8BVF
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![BU of 8bvf by Molmil](/molmil-images/mine/8bvf) | MoeA2 from Corynebacterium glutamicum in complex with FtsZ-CTD | 分子名称: | Cell division protein FtsZ, Molybdopterin molybdenumtransferase, SODIUM ION, ... | 著者 | Martinez, M, Haouz, A, Wehenkel, A.M, Alzari, P.M. | 登録日 | 2022-12-03 | 公開日 | 2023-02-22 | 最終更新日 | 2024-06-19 | 実験手法 | X-RAY DIFFRACTION (2.68 Å) | 主引用文献 | Eukaryotic-like gephyrin and cognate membrane receptor coordinate corynebacterial cell division and polar elongation. Biorxiv, 2023
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1WCS
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![BU of 1wcs by Molmil](/molmil-images/mine/1wcs) | A mutant of Trypanosoma rangeli sialidase displaying trans-sialidase activity | 分子名称: | SIALIDASE | 著者 | Paris, G, Ratier, L, Amaya, M.F, Nguyen, T, Alzari, P.M, Frasch, C. | 登録日 | 2004-11-21 | 公開日 | 2004-12-15 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | A Sialidase Mutant Displaying Trans-Sialidase Activity J.Mol.Biol., 345, 2005
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7AL2
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6GAV
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![BU of 6gav by Molmil](/molmil-images/mine/6gav) | Extremely 'open' clamp structure of DNA gyrase: role of the Corynebacteriales GyrB specific insert | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, DNA gyrase subunit B,DNA gyrase subunit A | 著者 | Petrella, S, Capton, E, Alzari, P.M, Aubry, A, MAyer, C. | 登録日 | 2018-04-12 | 公開日 | 2019-02-20 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Overall Structures of Mycobacterium tuberculosis DNA Gyrase Reveal the Role of a Corynebacteriales GyrB-Specific Insert in ATPase Activity. Structure, 27, 2019
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6GAU
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![BU of 6gau by Molmil](/molmil-images/mine/6gau) | Extremely 'open' clamp structure of DNA gyrase: role of the Corynebacteriales GyrB specific insert | 分子名称: | DNA gyrase subunit B,DNA gyrase subunit A, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | 著者 | Petrella, S, Capton, E, Alzari, P.M, Aubry, A, Mayer, C. | 登録日 | 2018-04-12 | 公開日 | 2019-02-20 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | 主引用文献 | Overall Structures of Mycobacterium tuberculosis DNA Gyrase Reveal the Role of a Corynebacteriales GyrB-Specific Insert in ATPase Activity. Structure, 27, 2019
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3GIG
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![BU of 3gig by Molmil](/molmil-images/mine/3gig) | Crystal structure of phosphorylated DesKC in complex with AMP-PCP | 分子名称: | MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, Sensor histidine kinase desK | 著者 | Trajtenberg, F, Albanesi, D, Alzari, P.M, Buschiazzo, A, de Mendoza, D. | 登録日 | 2009-03-05 | 公開日 | 2009-09-15 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (3.502 Å) | 主引用文献 | Structural plasticity and catalysis regulation of a thermosensor histidine kinase Proc.Natl.Acad.Sci.USA, 106, 2009
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2JFR
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![BU of 2jfr by Molmil](/molmil-images/mine/2jfr) | Crystal structure of the PPM Ser-Thr phosphatase MsPP from Mycobacterium smegmatis in complex with phosphate at 0.83 A resolution | 分子名称: | CHLORIDE ION, MAGNESIUM ION, MANGANESE (II) ION, ... | 著者 | Bellinzoni, M, Wehenkel, A, Shepard, W, Alzari, P.M. | 登録日 | 2007-02-04 | 公開日 | 2007-07-24 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (0.83 Å) | 主引用文献 | Insights Into the Mechanism of Ppm Ser/Thr Phosphatases from the Atomic Resolution Structures of a Mycobacterial Enzyme Structure, 15, 2007
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6I2S
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![BU of 6i2s by Molmil](/molmil-images/mine/6i2s) | Crystal structure of the SucA domain of Mycobacterium smegmatis KGD (R802A) in complex with GarA, following 2-oxoglutarate soak | 分子名称: | (4S)-4-{3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-5-(2-{[(S)-hydroxy(phosphonooxy)phosphoryl]oxy}ethyl)-4-methyl-1,3lambda~5~-thiazol-2-yl}-4-hydroxybutanoic acid, CALCIUM ION, Glycogen accumulation regulator GarA, ... | 著者 | Wagner, T, Bellinzoni, M, Alzari, P.M. | 登録日 | 2018-11-01 | 公開日 | 2019-05-22 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structural insights into the functional versatility of an FHA domain protein in mycobacterial signaling. Sci.Signal., 12, 2019
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1RZV
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![BU of 1rzv by Molmil](/molmil-images/mine/1rzv) | Crystal structure of the glycogen synthase from Agrobacterium tumefaciens (non-complexed form) | 分子名称: | Glycogen synthase 1 | 著者 | Buschiazzo, A, Guerin, M.E, Ugalde, J.E, Ugalde, R.A, Shepard, W, Alzari, P.M. | 登録日 | 2003-12-29 | 公開日 | 2004-08-31 | 最終更新日 | 2017-10-11 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Crystal structure of glycogen synthase: homologous enzymes catalyze glycogen synthesis and degradation. Embo J., 23, 2004
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6I2R
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![BU of 6i2r by Molmil](/molmil-images/mine/6i2r) | Crystal structure of the SucA domain of Mycobacterium smegmatis KGD (alpha-ketoglutarate decarboxylase), mutant R802A, in complex with GarA | 分子名称: | CALCIUM ION, Glycogen accumulation regulator GarA, MAGNESIUM ION, ... | 著者 | Wagner, T, Bellinzoni, M, Alzari, P.M. | 登録日 | 2018-11-01 | 公開日 | 2019-05-22 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structural insights into the functional versatility of an FHA domain protein in mycobacterial signaling. Sci.Signal., 12, 2019
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1RZU
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![BU of 1rzu by Molmil](/molmil-images/mine/1rzu) | Crystal structure of the glycogen synthase from A. tumefaciens in complex with ADP | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Glycogen synthase 1 | 著者 | Buschiazzo, A, Guerin, M.E, Ugalde, J.E, Ugalde, R.A, Shepard, W, Alzari, P.M. | 登録日 | 2003-12-29 | 公開日 | 2004-08-31 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Crystal structure of glycogen synthase: homologous enzymes catalyze glycogen synthesis and degradation. Embo J., 23, 2004
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1S0I
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![BU of 1s0i by Molmil](/molmil-images/mine/1s0i) | Trypanosoma cruzi trans-sialidase in complex with sialyl-lactose (Michaelis complex) | 分子名称: | N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-4)-alpha-D-glucopyranose, trans-sialidase | 著者 | Amaya, M.F, Watts, A.G, Damager, I, Wehenkel, A, Nguyen, T, Buschiazzo, A, Paris, G, Frasch, A.C, Withers, S.G, Alzari, P.M. | 登録日 | 2003-12-31 | 公開日 | 2004-05-18 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Structural Insights into the Catalytic Mechanism of Trypanosoma cruzi trans-Sialidase. Structure, 12, 2004
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2V57
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![BU of 2v57 by Molmil](/molmil-images/mine/2v57) | Crystal structure of the TetR-like transcriptional regulator LfrR from Mycobacterium smegmatis in complex with proflavine | 分子名称: | ISOPROPYL ALCOHOL, PROFLAVIN, SULFATE ION, ... | 著者 | Bellinzoni, M, Buroni, S, Riccardi, G, De Rossi, E, Alzari, P.M. | 登録日 | 2008-10-02 | 公開日 | 2009-10-20 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structural Plasticity and Distinct Drug-Binding Modes of Lfrr, a Mycobacterial Efflux Pump Regulator. J.Bacteriol., 191, 2009
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1S0J
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![BU of 1s0j by Molmil](/molmil-images/mine/1s0j) | Trypanosoma cruzi trans-sialidase in complex with MuNANA (Michaelis complex) | 分子名称: | 4-METHYL-2-OXO-2H-CHROMEN-7-YL 5-(ACETYLAMINO)-3,5-DIDEOXY-L-ERYTHRO-NON-2-ULOPYRANOSIDONIC ACID, trans-sialidase | 著者 | Amaya, M.F, Watts, A.G, Damager, I, Wehenkel, A, Nguyen, T, Buschiazzo, A, Paris, G, Frasch, A.C, Withers, S.G, Alzari, P.M. | 登録日 | 2003-12-31 | 公開日 | 2004-05-18 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Structural Insights into the Catalytic Mechanism of Trypanosoma cruzi trans-Sialidase. Structure, 12, 2004
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1GV4
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2JFS
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![BU of 2jfs by Molmil](/molmil-images/mine/2jfs) | Crystal structure of the PPM Ser-Thr phosphatase MsPP from Mycobacterium smegmatis in complex with cacodylate | 分子名称: | CACODYLATE ION, GLYCEROL, MANGANESE (II) ION, ... | 著者 | Bellinzoni, M, Wehenkel, A, Shepard, W, Alzari, P.M. | 登録日 | 2007-02-04 | 公開日 | 2007-07-24 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | 主引用文献 | Insights Into the Mechanism of Ppm Ser/Thr Phosphatases from the Atomic Resolution Structures of a Mycobacterial Enzyme Structure, 15, 2007
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5LVP
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![BU of 5lvp by Molmil](/molmil-images/mine/5lvp) | Human PDK1 Kinase Domain in Complex with an HM-Peptide Bound to the PIF-Pocket | 分子名称: | 3-phosphoinositide-dependent protein kinase 1, ADENOSINE-5'-TRIPHOSPHATE, CHLORIDE ION, ... | 著者 | Schulze, J.O, Saladino, G, Busschots, K, Neimanis, S, Suess, E, Odadzic, D, Zeuzem, S, Hindie, V, Herbrand, A.K, Lisa, M.N, Alzari, P.M, Gervasio, F.L, Biondi, R.M. | 登録日 | 2016-09-14 | 公開日 | 2016-10-19 | 最終更新日 | 2019-10-16 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Bidirectional Allosteric Communication between the ATP-Binding Site and the Regulatory PIF Pocket in PDK1 Protein Kinase. Cell Chem Biol, 23, 2016
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2JFT
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![BU of 2jft by Molmil](/molmil-images/mine/2jft) | Crystal structure of the PPM Ser-Thr phosphatase MsPP from Mycobacterium smegmatis in complex with sulfate | 分子名称: | MAGNESIUM ION, MANGANESE (II) ION, SER-THR PHOSPHATASE MSPP, ... | 著者 | Bellinzoni, M, Wehenkel, A, Shepard, W, Alzari, P.M. | 登録日 | 2007-02-04 | 公開日 | 2007-07-24 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.08 Å) | 主引用文献 | Insights Into the Mechanism of Ppm Ser/Thr Phosphatases from the Atomic Resolution Structures of a Mycobacterial Enzyme Structure, 15, 2007
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2AGS
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![BU of 2ags by Molmil](/molmil-images/mine/2ags) | Trypanosoma rangeli Sialidase in Complex with 2-Keto-3-deoxy-D-glycero-D-galacto-2,3-difluoro-nononic acid (2,3-difluoro-KDN) | 分子名称: | 3-deoxy-3-fluoro-D-erythro-alpha-L-manno-non-2-ulopyranosonic acid, SULFATE ION, sialidase | 著者 | Amaya, M.F, Alzari, P.M, Buschiazzo, A. | 登録日 | 2005-07-27 | 公開日 | 2005-11-22 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Structural and Kinetic Analysis of Two Covalent Sialosyl-Enzyme Intermediates on Trypanosoma rangeli Sialidase. J.Biol.Chem., 281, 2006
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2A75
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![BU of 2a75 by Molmil](/molmil-images/mine/2a75) | Trypanosoma rangeli Sialidase In Complex With 2,3- Difluorosialic Acid (Covalent Intermediate) | 分子名称: | 5-acetamido-3,5-dideoxy-3-fluoro-D-erythro-alpha-L-manno-non-2-ulopyranosonic acid, SULFATE ION, sialidase | 著者 | Amaya, M.F, Alzari, P.M, Buschiazzo, A. | 登録日 | 2005-07-04 | 公開日 | 2005-11-22 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Structural and Kinetic Analysis of Two Covalent Sialosyl-Enzyme Intermediates on Trypanosoma rangeli Sialidase. J.Biol.Chem., 281, 2006
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