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PDB: 11 件

6ULX
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BU of 6ulx by Molmil
Adenylation domain of a keto acid-selecting NRPS module bound to keto acyl adenylate space group P43212
分子名称: 5'-O-{(S)-hydroxy[(4-methyl-2-oxopentanoyl)oxy]phosphoryl}adenosine, Amino acid adenylation domain-containing protein, SULFATE ION
著者Alonzo, D.A, Chiche-Lapierre, C, Schmeing, T.M.
登録日2019-10-08
公開日2020-02-19
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.31 Å)
主引用文献Structural basis of keto acid utilization in nonribosomal depsipeptide synthesis.
Nat.Chem.Biol., 16, 2020
6ECD
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BU of 6ecd by Molmil
Vlm2 thioesterase domain with genetically encoded 2,3-diaminopropionic acid bound with a tetradepsipeptide
分子名称: Vlm2, tetradepsipeptide
著者Alonzo, D.A, Huguenin-Dezot, N, Heberlig, G.W, Mahesh, M, Nguyen, D.P, Dornan, M.H, Boddy, C.N, Chin, J.W, Schmeing, T.M.
登録日2018-08-07
公開日2018-12-12
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Trapping biosynthetic acyl-enzyme intermediates with encoded 2,3-diaminopropionic acid.
Nature, 565, 2019
6ECF
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BU of 6ecf by Molmil
Vlm2 thioesterase domain with genetically encoded 2,3-diaminopropionic acid bound with a dodecadepsipeptide, space group P1
分子名称: Vlm2, dodecadepsipeptide
著者Alonzo, D.A, Huguenin-Dezot, N, Heberlig, G.W, Mahesh, M, Nguyen, D.P, Dornan, M.H, Boddy, C.N, Chin, J.W, Schmeing, T.M.
登録日2018-08-07
公開日2018-12-12
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Trapping biosynthetic acyl-enzyme intermediates with encoded 2,3-diaminopropionic acid.
Nature, 565, 2019
6ECB
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BU of 6ecb by Molmil
Vlm2 thioesterase domain wild type structure 1
分子名称: Vlm2
著者Alonzo, D.A, Schmeing, T.M.
登録日2018-08-07
公開日2018-12-12
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Trapping biosynthetic acyl-enzyme intermediates with encoded 2,3-diaminopropionic acid.
Nature, 565, 2019
6ECE
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BU of 6ece by Molmil
Vlm2 thioesterase domain with genetically encoded 2,3-diaminopropionic acid bound with a dodecadepsipeptide, space group H3
分子名称: Vlm2, dodecadepsipeptide
著者Alonzo, D.A, Huguenin-Dezot, N, Heberlig, G.W, Mahesh, M, Nguyen, D.P, Dornan, M.H, Boddy, C.N, Chin, J.W, Schmeing, T.M.
登録日2018-08-07
公開日2018-12-12
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Trapping biosynthetic acyl-enzyme intermediates with encoded 2,3-diaminopropionic acid.
Nature, 565, 2019
6ECC
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BU of 6ecc by Molmil
Vlm2 thioesterase domain wild type structure 2
分子名称: Vlm2
著者Alonzo, D.A, Schmeing, T.M.
登録日2018-08-07
公開日2018-12-12
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Trapping biosynthetic acyl-enzyme intermediates with encoded 2,3-diaminopropionic acid.
Nature, 565, 2019
6ULW
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BU of 6ulw by Molmil
Adenylation, ketoreductase, and pseudo Asub multidomain structure of a keto acid-selecting NRPS module
分子名称: Amino acid adenylation domain-containing protein, CALCIUM ION, MAGNESIUM ION
著者Alonzo, D.A, Wang, J, Chiche-Lapierre, C, Schmeing, T.M.
登録日2019-10-08
公開日2020-02-19
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献Structural basis of keto acid utilization in nonribosomal depsipeptide synthesis.
Nat.Chem.Biol., 16, 2020
6ULY
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BU of 6uly by Molmil
Adenylation domain of a keto acid-selecting NRPS module bound to keto acyl adenylate space group P212121
分子名称: 5'-O-{(S)-hydroxy[(4-methyl-2-oxopentanoyl)oxy]phosphoryl}adenosine, Amino acid adenylation domain-containing protein, GLYCEROL, ...
著者Alonzo, D.A, Chiche-Lapierre, C, Schmeing, T.M.
登録日2019-10-08
公開日2020-02-19
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural basis of keto acid utilization in nonribosomal depsipeptide synthesis.
Nat.Chem.Biol., 16, 2020
6ULZ
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BU of 6ulz by Molmil
Adenylation domain of the initiation module of LgrA mutant P483M
分子名称: 3-METHYL-2-OXOBUTANOIC ACID, DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, FORMIC ACID, ...
著者Chiche-Lapierre, C, Alonzo, D.A, Schmeing, T.M.
登録日2019-10-08
公開日2020-02-19
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Structural basis of keto acid utilization in nonribosomal depsipeptide synthesis.
Nat.Chem.Biol., 16, 2020
5DUA
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BU of 5dua by Molmil
First condensation domain of the calcium-dependent antibiotic synthetase in complex with substrate analogue 3a
分子名称: CDA peptide synthetase I, CHLORIDE ION, N-pentyl-L-alaninamide
著者Bloudoff, K, Alonzo, D.A, Schmeing, T.M.
登録日2015-09-18
公開日2016-03-30
最終更新日2020-01-08
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Chemical Probes Allow Structural Insight into the Condensation Reaction of Nonribosomal Peptide Synthetases.
Cell Chem Biol, 23, 2016
5DU9
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BU of 5du9 by Molmil
First condensation domain of the calcium-dependent antibiotic synthetase in complex with substrate analogue 2a
分子名称: (2S)-2-amino-N-butyl-propanamide, CDA peptide synthetase I, CHLORIDE ION, ...
著者Bloudoff, K, Alonzo, D.A, Schmeing, T.M.
登録日2015-09-18
公開日2016-03-30
最終更新日2020-01-08
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Chemical Probes Allow Structural Insight into the Condensation Reaction of Nonribosomal Peptide Synthetases.
Cell Chem Biol, 23, 2016

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件を2024-10-30に公開中

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