6ULX
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6ECD
| Vlm2 thioesterase domain with genetically encoded 2,3-diaminopropionic acid bound with a tetradepsipeptide | 分子名称: | Vlm2, tetradepsipeptide | 著者 | Alonzo, D.A, Huguenin-Dezot, N, Heberlig, G.W, Mahesh, M, Nguyen, D.P, Dornan, M.H, Boddy, C.N, Chin, J.W, Schmeing, T.M. | 登録日 | 2018-08-07 | 公開日 | 2018-12-12 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Trapping biosynthetic acyl-enzyme intermediates with encoded 2,3-diaminopropionic acid. Nature, 565, 2019
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6ECF
| Vlm2 thioesterase domain with genetically encoded 2,3-diaminopropionic acid bound with a dodecadepsipeptide, space group P1 | 分子名称: | Vlm2, dodecadepsipeptide | 著者 | Alonzo, D.A, Huguenin-Dezot, N, Heberlig, G.W, Mahesh, M, Nguyen, D.P, Dornan, M.H, Boddy, C.N, Chin, J.W, Schmeing, T.M. | 登録日 | 2018-08-07 | 公開日 | 2018-12-12 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Trapping biosynthetic acyl-enzyme intermediates with encoded 2,3-diaminopropionic acid. Nature, 565, 2019
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6ECB
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6ECE
| Vlm2 thioesterase domain with genetically encoded 2,3-diaminopropionic acid bound with a dodecadepsipeptide, space group H3 | 分子名称: | Vlm2, dodecadepsipeptide | 著者 | Alonzo, D.A, Huguenin-Dezot, N, Heberlig, G.W, Mahesh, M, Nguyen, D.P, Dornan, M.H, Boddy, C.N, Chin, J.W, Schmeing, T.M. | 登録日 | 2018-08-07 | 公開日 | 2018-12-12 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Trapping biosynthetic acyl-enzyme intermediates with encoded 2,3-diaminopropionic acid. Nature, 565, 2019
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6ECC
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6ULW
| Adenylation, ketoreductase, and pseudo Asub multidomain structure of a keto acid-selecting NRPS module | 分子名称: | Amino acid adenylation domain-containing protein, CALCIUM ION, MAGNESIUM ION | 著者 | Alonzo, D.A, Wang, J, Chiche-Lapierre, C, Schmeing, T.M. | 登録日 | 2019-10-08 | 公開日 | 2020-02-19 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | 主引用文献 | Structural basis of keto acid utilization in nonribosomal depsipeptide synthesis. Nat.Chem.Biol., 16, 2020
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6ULY
| Adenylation domain of a keto acid-selecting NRPS module bound to keto acyl adenylate space group P212121 | 分子名称: | 5'-O-{(S)-hydroxy[(4-methyl-2-oxopentanoyl)oxy]phosphoryl}adenosine, Amino acid adenylation domain-containing protein, GLYCEROL, ... | 著者 | Alonzo, D.A, Chiche-Lapierre, C, Schmeing, T.M. | 登録日 | 2019-10-08 | 公開日 | 2020-02-19 | 最終更新日 | 2024-10-09 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structural basis of keto acid utilization in nonribosomal depsipeptide synthesis. Nat.Chem.Biol., 16, 2020
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6ULZ
| Adenylation domain of the initiation module of LgrA mutant P483M | 分子名称: | 3-METHYL-2-OXOBUTANOIC ACID, DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, FORMIC ACID, ... | 著者 | Chiche-Lapierre, C, Alonzo, D.A, Schmeing, T.M. | 登録日 | 2019-10-08 | 公開日 | 2020-02-19 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Structural basis of keto acid utilization in nonribosomal depsipeptide synthesis. Nat.Chem.Biol., 16, 2020
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5DUA
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5DU9
| First condensation domain of the calcium-dependent antibiotic synthetase in complex with substrate analogue 2a | 分子名称: | (2S)-2-amino-N-butyl-propanamide, CDA peptide synthetase I, CHLORIDE ION, ... | 著者 | Bloudoff, K, Alonzo, D.A, Schmeing, T.M. | 登録日 | 2015-09-18 | 公開日 | 2016-03-30 | 最終更新日 | 2020-01-08 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Chemical Probes Allow Structural Insight into the Condensation Reaction of Nonribosomal Peptide Synthetases. Cell Chem Biol, 23, 2016
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