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PDB: 11 results

2QMP
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Crystal Structure of HIV-1 protease complexed with PL-100
Descriptor: N-[(5S)-5-{[(4-aminophenyl)sulfonyl](isobutyl)amino}-6-hydroxyhexyl]-Nalpha-(methoxycarbonyl)-beta-phenyl-L-phenylalaninamide, Pol polyprotein
Authors:Allison, T.J.
Deposit date:2007-07-16
Release date:2008-07-22
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal Structure of HIV-1 protease complexed with PL-100
To be Published
1A62
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CRYSTAL STRUCTURE OF THE RNA-BINDING DOMAIN OF THE TRANSCRIPTIONAL TERMINATOR PROTEIN RHO
Descriptor: RHO
Authors:Allison, T.J, Wood, T.C, Briercheck, D.M, Rastinejad, F, Richardson, J.P, Rule, G.S.
Deposit date:1998-03-05
Release date:1998-06-17
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Crystal structure of the RNA-binding domain from transcription termination factor rho.
Nat.Struct.Biol., 5, 1998
3H0B
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Discovery of aminoheterocycles as a novel beta-secretase inhibitor class
Descriptor: 4-[(1S)-1-(3-fluoro-4-methoxyphenyl)-2-(2-methoxy-5-nitrophenyl)ethyl]-1H-imidazol-2-amine, Beta-secretase 1
Authors:Allison, T.J.
Deposit date:2009-04-08
Release date:2009-07-07
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Discovery of aminoheterocycles as a novel beta-secretase inhibitor class: pH dependence on binding activity part 1.
Bioorg.Med.Chem.Lett., 19, 2009
3EXO
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Crystal structure of BACE1 bound to inhibitor
Descriptor: Beta-secretase 1, GLYCEROL, N-{2-methyl-5-[(6-phenylpyrimidin-4-yl)amino]phenyl}methanesulfonamide, ...
Authors:Allison, T.J.
Deposit date:2008-10-16
Release date:2009-02-03
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Identification of a small molecule beta-secretase inhibitor that binds without catalytic aspartate engagement.
Bioorg.Med.Chem.Lett., 19, 2009
1HXM
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Crystal Structure of a Human Vgamma9/Vdelta2 T Cell Receptor
Descriptor: GAMMA-DELTA T-CELL RECEPTOR, SULFATE ION
Authors:Allison, T.J, Winter, C.C, Fournie, J.J, Bonneville, M, Garboczi, D.N.
Deposit date:2001-01-16
Release date:2001-06-20
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (3.12 Å)
Cite:Structure of a human gammadelta T-cell antigen receptor.
Nature, 411, 2001
2ZJM
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Crystal structure of the human BACE1 catalytic domain in complex with N-[1-(5-chloro-2-isopropoxy-3-methoxy-benzyl)-piperidin-4-yl]-2-(4-sulfamoyl-phenoxy)-acetamide
Descriptor: Beta-secretase 1, N-{1-[5-chloro-3-methoxy-2-(1-methylethoxy)benzyl]piperidin-4-yl}-2-(4-sulfamoylphenoxy)acetamide
Authors:Allison, T.J, Pham, P, Romanowski, M.J, Munshi, S.K.
Deposit date:2008-03-07
Release date:2009-01-20
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Fragment-based discovery of novel BACE1 inhibitors using Tethering technology
To be Published
1HNA
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CRYSTAL STRUCTURE OF HUMAN CLASS MU GLUTATHIONE TRANSFERASE GSTM2-2: EFFECTS OF LATTICE PACKING ON CONFORMATIONAL HETEROGENEITY
Descriptor: GLUTATHIONE S-(2,4 DINITROBENZENE), GLUTATHIONE S-TRANSFERASE
Authors:Raghunathan, S, Chandross, R.J, Kretsinger, R.H, Allison, T.J, Penington, C.J, Rule, G.S.
Deposit date:1993-10-15
Release date:1994-01-31
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Crystal structure of human class mu glutathione transferase GSTM2-2. Effects of lattice packing on conformational heterogeneity.
J.Mol.Biol., 238, 1994
1A63
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THE NMR STRUCTURE OF THE RNA BINDING DOMAIN OF E.COLI RHO FACTOR SUGGESTS POSSIBLE RNA-PROTEIN INTERACTIONS, 10 STRUCTURES
Descriptor: RHO
Authors:Briercheck, D.M, Wood, T.C, Allison, T.J, Richardson, J.P, Rule, G.S.
Deposit date:1998-03-05
Release date:1998-05-27
Last modified:2024-04-10
Method:SOLUTION NMR
Cite:The NMR structure of the RNA binding domain of E. coli rho factor suggests possible RNA-protein interactions.
Nat.Struct.Biol., 5, 1998
1HNB
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CRYSTAL STRUCTURE OF HUMAN CLASS MU GLUTATHIONE TRANSFERASE GSTM2-2: EFFECTS OF LATTICE PACKING ON CONFORMATIONAL HETEROGENEITY
Descriptor: GLUTATHIONE S-(2,4 DINITROBENZENE), GLUTATHIONE S-TRANSFERASE
Authors:Raghunathan, S, Chandross, R.J, Kretsinger, R.H, Allison, T.J, Penington, C.J, Rule, G.S.
Deposit date:1993-10-15
Release date:1994-01-31
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Crystal structure of human class mu glutathione transferase GSTM2-2. Effects of lattice packing on conformational heterogeneity.
J.Mol.Biol., 238, 1994
1HNC
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CRYSTAL STRUCTURE OF HUMAN CLASS MU GLUTATHIONE TRANSFERASE GSTM2-2: EFFECTS OF LATTICE PACKING ON CONFORMATIONAL HETEROGENEITY
Descriptor: GLUTATHIONE S-(2,4 DINITROBENZENE), GLUTATHIONE S-TRANSFERASE
Authors:Raghunathan, S, Chandross, R.J, Kretsinger, R.H, Allison, T.J, Penington, C.J, Rule, G.S.
Deposit date:1993-10-15
Release date:1994-01-31
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (3 Å)
Cite:Crystal structure of human class mu glutathione transferase GSTM2-2. Effects of lattice packing on conformational heterogeneity.
J.Mol.Biol., 238, 1994
1YPY
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Crystal Structure of Vaccinia Virus L1 protein
Descriptor: Virion membrane protein
Authors:Su, H.P, Garman, S.C, Allison, T.J, Fogg, C, Moss, B, Garboczi, D.N.
Deposit date:2005-01-31
Release date:2005-03-01
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (1.51 Å)
Cite:The 1.51-Angstrom structure of the poxvirus L1 protein, a target of potent neutralizing antibodies.
Proc.Natl.Acad.Sci.Usa, 102, 2005

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