8CSL
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![BU of 8csl by Molmil](/molmil-images/mine/8csl) | Sub-tomogram averaging of erythrocyte ankyrin-1 complex | Descriptor: | Ammonium transporter Rh type A, Ankyrin-1, Band 3 anion transport protein, ... | Authors: | Vallese, F, Kim, K, Yen, L.Y, Johnston, J.D, Noble, A.J, Cali, T, Clarke, O.B. | Deposit date: | 2022-05-12 | Release date: | 2022-07-20 | Last modified: | 2024-02-14 | Method: | ELECTRON MICROSCOPY (25 Å) | Cite: | Architecture of the human erythrocyte ankyrin-1 complex. Nat.Struct.Mol.Biol., 29, 2022
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7JGT
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![BU of 7jgt by Molmil](/molmil-images/mine/7jgt) | Crystal Structure of FN3tt | Descriptor: | Fibronectin type-III domain-containing protein | Authors: | Luo, J, Malia, T.J. | Deposit date: | 2020-07-19 | Release date: | 2021-07-21 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Surface salt bridges contribute to the extreme thermal stability of an FN3-like domain from a thermophilic bacterium. Proteins, 90, 2022
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8BLJ
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![BU of 8blj by Molmil](/molmil-images/mine/8blj) | Crystal structure of the ligand-binding domain (LBD) of human iGluR Delta-1 (GluD1), apo state | Descriptor: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | Authors: | Heroven, C, Malinauskas, T, Aricescu, A.R. | Deposit date: | 2022-11-09 | Release date: | 2023-11-22 | Last modified: | 2024-01-03 | Method: | X-RAY DIFFRACTION (2.18 Å) | Cite: | GluD1 binds GABA and controls inhibitory plasticity. Science, 382, 2023
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3L5W
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![BU of 3l5w by Molmil](/molmil-images/mine/3l5w) | Crystal structure of the complex between IL-13 and C836 FAB | Descriptor: | C836 HEAVY CHAIN, C836 LIGHT CHAIN, GLYCEROL, ... | Authors: | Teplyakov, A, Obmolova, G, Malia, T, Gilliland, G.L. | Deposit date: | 2009-12-22 | Release date: | 2010-04-14 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Human framework adaptation of a mouse anti-human IL-13 antibody. J.Mol.Biol., 398, 2010
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3L7F
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![BU of 3l7f by Molmil](/molmil-images/mine/3l7f) | Structure of IL-13 antibody H2L6, A humanized variant OF C836 | Descriptor: | CALCIUM ION, H2L6 HEAVY CHAIN, H2L6 LIGHT CHAIN, ... | Authors: | Teplyakov, A, Obmolova, G, Malia, T, Gilliland, G.L. | Deposit date: | 2009-12-28 | Release date: | 2010-11-10 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Human framework adaptation of a mouse anti-human IL-13 antibody. J.Mol.Biol., 398, 2010
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8BEJ
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![BU of 8bej by Molmil](/molmil-images/mine/8bej) | GABA-A receptor a5 homomer - a5V3 - APO | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Gamma-aminobutyric acid receptor subunit alpha-5 | Authors: | Miller, P.S, Malinauskas, T.M, Hardwick, S.W, Chirgadze, D.Y. | Deposit date: | 2022-10-21 | Release date: | 2023-11-01 | Last modified: | 2023-12-27 | Method: | ELECTRON MICROSCOPY (3.24 Å) | Cite: | The molecular basis of drug selectivity for alpha 5 subunit-containing GABA A receptors. Nat.Struct.Mol.Biol., 30, 2023
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8BHM
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![BU of 8bhm by Molmil](/molmil-images/mine/8bhm) | GABA-A receptor a5 homomer - a5V3 - DMCM | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Gamma-aminobutyric acid receptor subunit alpha-5, methyl 4-ethyl-6,7-dimethoxy-9H-pyrido[3,4-b]indole-3-carboxylate | Authors: | Miller, P.S, Malinauskas, T.M, Hardwick, S.W, Chirgadze, D.Y. | Deposit date: | 2022-10-31 | Release date: | 2023-11-01 | Last modified: | 2023-12-27 | Method: | ELECTRON MICROSCOPY (2.95 Å) | Cite: | The molecular basis of drug selectivity for alpha 5 subunit-containing GABA A receptors. Nat.Struct.Mol.Biol., 30, 2023
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8BHI
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![BU of 8bhi by Molmil](/molmil-images/mine/8bhi) | GABA-A receptor a5 homomer - a5V3 - RO5211223 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Gamma-aminobutyric acid receptor subunit alpha-5, [1,1-bis(oxidanylidene)-1,4-thiazinan-4-yl]-[6-[[5-methyl-3-(6-methylpyridin-3-yl)-1,2-oxazol-4-yl]methoxy]pyridin-3-yl]methanone | Authors: | Miller, P.S, Malinauskas, T.M, Hardwick, S.W, Chirgadze, D.Y. | Deposit date: | 2022-10-31 | Release date: | 2023-11-01 | Last modified: | 2023-12-27 | Method: | ELECTRON MICROSCOPY (2.67 Å) | Cite: | The molecular basis of drug selectivity for alpha 5 subunit-containing GABA A receptors. Nat.Struct.Mol.Biol., 30, 2023
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8BHK
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![BU of 8bhk by Molmil](/molmil-images/mine/8bhk) | GABA-A receptor a5 homomer - a5V3 - Diazepam | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 7-CHLORO-1-METHYL-5-PHENYL-1,3-DIHYDRO-2H-1,4-BENZODIAZEPIN-2-ONE, Gamma-aminobutyric acid receptor subunit alpha-5 | Authors: | Miller, P.S, Malinauskas, T.M, Kasaragod, V.B, Chirgadze, D.Y. | Deposit date: | 2022-10-31 | Release date: | 2023-11-01 | Last modified: | 2023-12-27 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | The molecular basis of drug selectivity for alpha 5 subunit-containing GABA A receptors. Nat.Struct.Mol.Biol., 30, 2023
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8BHO
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![BU of 8bho by Molmil](/molmil-images/mine/8bho) | GABA-A receptor a5 homomer - a5V3 - L655708 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Gamma-aminobutyric acid receptor subunit alpha-5, ethyl (7~{S})-15-methoxy-12-oxidanylidene-2,4,11-triazatetracyclo[11.4.0.0^{2,6}.0^{7,11}]heptadeca-1(17),3,5,13,15-pentaene-5-carboxylate | Authors: | Miller, P.S, Malinauskas, T.M, Hardwick, S.W, Chirgadze, D.Y. | Deposit date: | 2022-10-31 | Release date: | 2023-11-01 | Last modified: | 2023-12-27 | Method: | ELECTRON MICROSCOPY (2.93 Å) | Cite: | The molecular basis of drug selectivity for alpha 5 subunit-containing GABA A receptors. Nat.Struct.Mol.Biol., 30, 2023
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8BHQ
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![BU of 8bhq by Molmil](/molmil-images/mine/8bhq) | GABA-A receptor a5 homomer - a5V3 - RO7172670 | Descriptor: | 2-[[5-methyl-3-(6-methylpyridazin-3-yl)-1,2-oxazol-4-yl]methyl]-5-(5-oxa-2-azaspiro[3.5]nonan-2-yl)pyridazin-3-one, 2-acetamido-2-deoxy-beta-D-glucopyranose, Gamma-aminobutyric acid receptor subunit alpha-5 | Authors: | Miller, P.S, Malinauskas, T.M, Hardwick, S.W, Kasaragod, V.B. | Deposit date: | 2022-10-31 | Release date: | 2023-11-01 | Last modified: | 2023-12-27 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | The molecular basis of drug selectivity for alpha 5 subunit-containing GABA A receptors. Nat.Struct.Mol.Biol., 30, 2023
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8BHS
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![BU of 8bhs by Molmil](/molmil-images/mine/8bhs) | GABA-A receptor a5 homomer - a5V3 - RO4938581 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 5-[bis(fluoranyl)methyl]-15-bromanyl-2,4,8,9,11-pentazatetracyclo[11.4.0.0^{2,6}.0^{8,12}]heptadeca-1(13),3,5,9,11,14,16-heptaene, Gamma-aminobutyric acid receptor subunit alpha-5 | Authors: | Miller, P.S, Malinauskas, T.M, Hardwick, S.W, Chirgadze, D.Y. | Deposit date: | 2022-10-31 | Release date: | 2023-11-01 | Last modified: | 2023-12-27 | Method: | ELECTRON MICROSCOPY (3.24 Å) | Cite: | The molecular basis of drug selectivity for alpha 5 subunit-containing GABA A receptors. Nat.Struct.Mol.Biol., 30, 2023
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8BHR
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![BU of 8bhr by Molmil](/molmil-images/mine/8bhr) | GABA-A receptor a5 homomer - a5V3 - RO7015738 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 6-[[5-methyl-3-(6-methylpyridin-3-yl)-1,2-oxazol-4-yl]methoxy]-~{N}-[(2~{S})-1-oxidanylpentan-2-yl]pyridine-3-carboxamide, Gamma-aminobutyric acid receptor subunit alpha-5 | Authors: | Miller, P.S, Malinauskas, T.M, Kasaragod, V.B. | Deposit date: | 2022-10-31 | Release date: | 2023-11-01 | Last modified: | 2023-12-27 | Method: | ELECTRON MICROSCOPY (3.38 Å) | Cite: | The molecular basis of drug selectivity for alpha 5 subunit-containing GABA A receptors. Nat.Struct.Mol.Biol., 30, 2023
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8CRQ
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![BU of 8crq by Molmil](/molmil-images/mine/8crq) | Local refinement of Band 3-I transmembrane domains, class 1 of erythrocyte ankyrin-1 complex | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Band 3 anion transport protein, CHOLESTEROL, ... | Authors: | Vallese, F, Kim, K, Yen, L.Y, Johnston, J.D, Noble, A.J, Cali, T, Clarke, O.B. | Deposit date: | 2022-05-11 | Release date: | 2022-07-20 | Last modified: | 2022-07-27 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Architecture of the human erythrocyte ankyrin-1 complex. Nat.Struct.Mol.Biol., 29, 2022
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8CRR
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![BU of 8crr by Molmil](/molmil-images/mine/8crr) | Local refinement of Band 3-III transmembrane domains, class 1 of erythrocyte ankyrin-1 complex | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Band 3 anion transport protein, CHOLESTEROL, ... | Authors: | Vallese, F, Kim, K, Yen, L.Y, Johnston, J.D, Noble, A.J, Cali, T, Clarke, O.B. | Deposit date: | 2022-05-11 | Release date: | 2022-07-20 | Last modified: | 2022-07-27 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Architecture of the human erythrocyte ankyrin-1 complex. Nat.Struct.Mol.Biol., 29, 2022
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8CRT
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![BU of 8crt by Molmil](/molmil-images/mine/8crt) | Local refinement of Rh trimer, glycophorin B and Band3-III transmembrane region, class 1a of erythrocyte ankyrin-1 complex | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Ammonium transporter Rh type A, Band 3 anion transport protein, ... | Authors: | Vallese, F, Kim, K, Yen, L.Y, Johnston, J.D, Noble, A.J, Cali, T, Clarke, O.B. | Deposit date: | 2022-05-11 | Release date: | 2022-07-20 | Last modified: | 2022-07-27 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Architecture of the human erythrocyte ankyrin-1 complex. Nat.Struct.Mol.Biol., 29, 2022
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4L4J
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![BU of 4l4j by Molmil](/molmil-images/mine/4l4j) | Crystal structure of fc-fragment of human IgG2-Sigma antibody | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, ... | Authors: | Teplyakov, A, Malia, T, Gillilang, G. | Deposit date: | 2013-06-07 | Release date: | 2013-08-28 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.92 Å) | Cite: | An engineered Fc variant of an IgG eliminates all immune effector functions via structural perturbations. Methods, 65, 2014
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3L5X
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![BU of 3l5x by Molmil](/molmil-images/mine/3l5x) | Crystal structure of the complex between IL-13 and H2L6 FAB | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, GLYCEROL, H2L6 HEAVY CHAIN, ... | Authors: | Teplyakov, A, Obmolova, G, Malia, T, Gilliland, G.L. | Deposit date: | 2009-12-22 | Release date: | 2010-04-14 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Human framework adaptation of a mouse anti-human IL-13 antibody. J.Mol.Biol., 398, 2010
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4M6A
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![BU of 4m6a by Molmil](/molmil-images/mine/4m6a) | N-Terminal beta-Strand Swapping in a Consensus Derived Alternative Scaffold Driven by Stabilizing Hydrophobic Interactions | Descriptor: | Tencon | Authors: | Luo, J, Teplyakov, A, Obmolova, G, Malia, T.J, Chan, W, Jocobs, S.A, O'neil, K.T, Gilliland, G.L. | Deposit date: | 2013-08-09 | Release date: | 2014-02-26 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.71 Å) | Cite: | N-terminal beta-strand swapping in a consensus-derived alternative scaffold driven by stabilizing hydrophobic interactions. Proteins, 82, 2014
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5I1H
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![BU of 5i1h by Molmil](/molmil-images/mine/5i1h) | CRYSTAL STRUCTURE OF HUMAN GERMLINE ANTIBODY IGHV3-53/IGKV3-20 | Descriptor: | FAB HEAVY CHAIN, FAB LIGHT CHAIN, SULFATE ION | Authors: | Teplyakov, A, Obmolova, G, Malia, T, Luo, J, Gilliland, G. | Deposit date: | 2016-02-05 | Release date: | 2016-06-08 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.222 Å) | Cite: | Structural diversity in a human antibody germline library. Mabs, 8, 2016
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5I1E
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![BU of 5i1e by Molmil](/molmil-images/mine/5i1e) | CRYSTAL STRUCTURE OF HUMAN GERMLINE ANTIBODY IGHV3-53/IGKV1-39 | Descriptor: | FAB HEAVY CHAIN, FAB LIGHT CHAIN, GLYCEROL, ... | Authors: | Teplyakov, A, Obmolova, G, Malia, T, Luo, J, Gilliland, G. | Deposit date: | 2016-02-05 | Release date: | 2016-06-08 | Last modified: | 2016-08-03 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structural diversity in a human antibody germline library. Mabs, 8, 2016
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5I18
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![BU of 5i18 by Molmil](/molmil-images/mine/5i18) | CRYSTAL STRUCTURE OF HUMAN GERMLINE ANTIBODY IGHV1-69/IGKV4-1 | Descriptor: | FAB HEAVY CHAIN, FAB LIGHT CHAIN, GLYCEROL | Authors: | Teplyakov, A, Obmolova, G, Malia, T, Luo, J, Gilliland, G. | Deposit date: | 2016-02-05 | Release date: | 2016-02-24 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.92 Å) | Cite: | Structural diversity in a human antibody germline library. Mabs, 8, 2016
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5I16
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![BU of 5i16 by Molmil](/molmil-images/mine/5i16) | CRYSTAL STRUCTURE OF HUMAN GERMLINE ANTIBODY IGHV1-69/IGKV3-11 | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, FAB HEAVY CHAIN, FAB LIGHT CHAIN, ... | Authors: | Teplyakov, A, Obmolova, G, Malia, T, Luo, J, Gilliland, G. | Deposit date: | 2016-02-05 | Release date: | 2016-06-08 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structural diversity in a human antibody germline library. Mabs, 8, 2016
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5I1K
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![BU of 5i1k by Molmil](/molmil-images/mine/5i1k) | CRYSTAL STRUCTURE OF HUMAN GERMLINE ANTIBODY IGHV5-51/IGKV3-20 | Descriptor: | 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, FAB HEAVY CHAIN, FAB LIGHT CHAIN, ... | Authors: | Teplyakov, A, Obmolova, G, Malia, T, Luo, J, Gilliland, G. | Deposit date: | 2016-02-05 | Release date: | 2016-06-08 | Last modified: | 2016-08-03 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Structural diversity in a human antibody germline library. Mabs, 8, 2016
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5I1C
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![BU of 5i1c by Molmil](/molmil-images/mine/5i1c) | CRYSTAL STRUCTURE OF HUMAN GERMLINE ANTIBODY IGHV3-23/IGKV3-20 | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, FAB HEAVY CHAIN, ... | Authors: | Teplyakov, A, Obmolova, G, Malia, T, Luo, J, Gilliland, G. | Deposit date: | 2016-02-05 | Release date: | 2016-06-08 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Structural diversity in a human antibody germline library. Mabs, 8, 2016
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