8BEJ

GABA-A receptor a5 homomer - a5V3 - APO

Summary for 8BEJ

• Entry DOI: 10.2210/pdb8bej/pdb
• EMDB information: 16005
• Descriptor: Gamma-aminobutyric acid receptor subunit alpha-5, 2-acetamido-2-deoxy-beta-D-glucopyranose (2 entities in total)
• Functional Keywords: plgic gaba neurotransmission, membrane protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 5
• Total formula weight: 206395.59

Authors

Miller, P.S.,Malinauskas, T.M.,Hardwick, S.W.,Chirgadze, D.Y. (deposition date: 2022-10-21, release date: 2023-11-01, Last modification date: 2023-12-27)

• Primary citation: Kasaragod, V.B.,Malinauskas, T.,Wahid, A.A.,Lengyel, J.,Knoflach, F.,Hardwick, S.W.,Jones, C.F.,Chen, W.N.,Lucas, X.,El Omari, K.,Chirgadze, D.Y.,Aricescu, A.R.,Cecere, G.,Hernandez, M.C.,Miller, P.S.; The molecular basis of drug selectivity for alpha 5 subunit-containing GABA A receptors.; Nat.Struct.Mol.Biol., 30:1936-1946, 2023; PubMed: 37903907; DOI: 10.1038/s41594-023-01133-1

Experimental method

ELECTRON MICROSCOPY (3.24 Å)