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PDB: 4 件
6UEP
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BU of 6uep by Molmil
Structure of A. thaliana TBP bound to a DNA site with a C-C mismatch
分子名称: DNA (5'-D(*GP*CP*TP*AP*TP*AP*AP*AP*CP*GP*GP*GP*CP*A)-3'), DNA (5'-D(*TP*GP*CP*CP*CP*CP*TP*TP*TP*AP*TP*AP*GP*C)-3'), FORMIC ACID, ...
著者Schumacher, M.A, Al-hashimi, H.
登録日2019-09-22
公開日2020-09-02
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献DNA mismatches reveal conformational penalties in protein-DNA recognition.
Nature, 587, 2020
6UER
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BU of 6uer by Molmil
Crystal form 2: Structure of TBP bound to C-C mismatch at pH 7
分子名称: DNA (5'-D(*GP*CP*TP*AP*TP*AP*AP*AP*CP*GP*GP*GP*CP*A)-3'), DNA (5'-D(*TP*GP*CP*CP*CP*CP*TP*TP*TP*AP*TP*AP*GP*C)-3'), TATA-box-binding protein 1
著者Schumacher, M.A, Al-Hashimi, H.
登録日2019-09-22
公開日2020-09-02
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献DNA mismatches reveal conformational penalties in protein-DNA recognition.
Nature, 587, 2020
6UEQ
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BU of 6ueq by Molmil
Structure of TBP bound to C-C mismatch containing TATA site
分子名称: DNA (5'-D(*GP*CP*TP*AP*TP*AP*AP*AP*AP*CP*GP*GP*CP*A)-3'), DNA (5'-D(*TP*GP*CP*CP*CP*TP*TP*TP*TP*AP*TP*AP*GP*C)-3'), SULFATE ION, ...
著者Schumacher, M.A, Al-Hashimi, H.
登録日2019-09-22
公開日2020-09-02
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献DNA mismatches reveal conformational penalties in protein-DNA recognition.
Nature, 587, 2020
8RXR
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BU of 8rxr by Molmil
Crystal structure of VPS34 in complex with inhibitor SB02024
分子名称: 4-[(3R)-3-methylmorpholin-4-yl]-2-[(2R)-2-(trifluoromethyl)piperidin-1-yl]-3H-pyridin-6-one, DI(HYDROXYETHYL)ETHER, DIMETHYL SULFOXIDE, ...
著者Tresaugues, L, Yu, Y, Bogdan, M, Parpal, S, Silvander, C, Lindstrom, J, Simeon, J, Timson, M.J, Al-Hashimi, H, Smith, B.D, Flynn, D.L, Viklund, J, Martinsson, J, De Milito, A, Andersson, M.
登録日2024-02-07
公開日2024-03-20
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.06 Å)
主引用文献Combining VPS34 inhibitors with STING agonists enhances type I interferon signaling and anti-tumor efficacy.
Mol Oncol, 2024

220113

件を2024-05-22に公開中

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