5HWS
 
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5AYV
 | | Crystal structure of archaeal ketopantoate reductase complexed with coenzyme A and 2-oxopantoate | | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, 2-dehydropantoate 2-reductase, ACETATE ION, ... | | Authors: | Aikawa, Y, Nishitani, Y, Miki, K. | | Deposit date: | 2015-09-08 | | Release date: | 2016-01-27 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (1.647 Å) | | Cite: | Crystal structure of archaeal ketopantoate reductase complexed with coenzyme a and 2-oxopantoate provides structural insights into feedback regulation
Proteins, 84, 2016
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6LUE
 | | Crystal structure of mouse Cryptochrome 1 in complex with compound KL201 | | Descriptor: | 2-bromanyl-N-(5,6,7,8-tetrahydro-[1]benzothiolo[2,3-d]pyrimidin-4-yl)benzamide, Cryptochrome-1 | | Authors: | Miller, S, Aikawa, Y, Hirota, T. | | Deposit date: | 2020-01-27 | | Release date: | 2020-06-10 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | An Isoform-Selective Modulator of Cryptochrome 1 Regulates Circadian Rhythms in Mammals.
Cell Chem Biol, 27, 2020
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7D0N
 | | Crystal structure of mouse CRY2 apo form | | Descriptor: | Cryptochrome-2 | | Authors: | Miller, S.A, Aikawa, Y, Hirota, T. | | Deposit date: | 2020-09-11 | | Release date: | 2021-06-23 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Structural differences in the FAD-binding pockets and lid loops of mammalian CRY1 and CRY2 for isoform-selective regulation.
Proc.Natl.Acad.Sci.USA, 118, 2021
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7DLI
 | | Crystal structure of mouse CRY1 in complex with KL001 compound | | Descriptor: | 1,2-ETHANEDIOL, Cryptochrome-1, N-[(2R)-3-carbazol-9-yl-2-oxidanyl-propyl]-N-(furan-2-ylmethyl)methanesulfonamide | | Authors: | Miller, S.A, Aikawa, Y, Hirota, T. | | Deposit date: | 2020-11-27 | | Release date: | 2021-06-23 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Structural differences in the FAD-binding pockets and lid loops of mammalian CRY1 and CRY2 for isoform-selective regulation.
Proc.Natl.Acad.Sci.USA, 118, 2021
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7D0M
 | | Crystal structure of mouse CRY1 with bound cryoprotectant | | Descriptor: | Cryptochrome-1, DI(HYDROXYETHYL)ETHER, TETRAETHYLENE GLYCOL | | Authors: | Miller, S.A, Aikawa, Y, Hirota, T. | | Deposit date: | 2020-09-11 | | Release date: | 2021-06-23 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | Structural differences in the FAD-binding pockets and lid loops of mammalian CRY1 and CRY2 for isoform-selective regulation.
Proc.Natl.Acad.Sci.USA, 118, 2021
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6KX8
 | | Crystal structure of mouse Cryptochrome 2 in complex with TH301 compound | | Descriptor: | 1-(4-chlorophenyl)-N-[2-(4-methoxyphenyl)-5,5-bis(oxidanylidene)-4,6-dihydrothieno[3,4-c]pyrazol-3-yl]cyclopentane-1-carboxamide, Cryptochrome-2 | | Authors: | Miller, S.A, Aikawa, Y, Hirota, T. | | Deposit date: | 2019-09-10 | | Release date: | 2020-04-01 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.25 Å) | | Cite: | Isoform-selective regulation of mammalian cryptochromes.
Nat.Chem.Biol., 16, 2020
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6KX5
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6KX4
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6KX6
 | | Crystal structure of mouse Cryptochrome 1 in complex with KL101 compound | | Descriptor: | Cryptochrome-1, ~{N}-[2-(2,4-dimethylphenyl)-4,6-dihydrothieno[3,4-c]pyrazol-3-yl]-3,4-dimethyl-benzamide | | Authors: | Miller, S.A, Aikawa, Y, Hirota, T. | | Deposit date: | 2019-09-10 | | Release date: | 2020-04-01 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Isoform-selective regulation of mammalian cryptochromes.
Nat.Chem.Biol., 16, 2020
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6KX7
 | | Crystal structure of mouse Cryptochrome 1 in complex with TH301 compound | | Descriptor: | 1-(4-chlorophenyl)-N-[2-(4-methoxyphenyl)-5,5-bis(oxidanylidene)-4,6-dihydrothieno[3,4-c]pyrazol-3-yl]cyclopentane-1-carboxamide, Cryptochrome-1 | | Authors: | Miller, S.A, Aikawa, Y, Hirota, T. | | Deposit date: | 2019-09-10 | | Release date: | 2020-04-01 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Isoform-selective regulation of mammalian cryptochromes.
Nat.Chem.Biol., 16, 2020
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3W1Z
 | | Heat shock protein 16.0 from Schizosaccharomyces pombe | | Descriptor: | Heat shock protein 16 | | Authors: | Hanazono, Y, Takeda, K, Akiyama, N, Aikawa, Y, Miki, K. | | Deposit date: | 2012-11-26 | | Release date: | 2013-03-13 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.401 Å) | | Cite: | Nonequivalence Observed for the 16-Meric Structure of a Small Heat Shock Protein, SpHsp16.0, from Schizosaccharomyces pombe
Structure, 21, 2013
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