Loading
PDBj
English日本語简体中文繁體中文한국어
✖
ﾒﾆｭｰPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
PDB: 49 件
3T9V
DownloadVisualize
BU of 3t9v by Molmil
CNQX bound to a reduced double cysteine mutant (A452C/S652C) of the ligand binding domain of GluA2
分子名称: 7-nitro-2,3-dioxo-2,3-dihydroquinoxaline-6-carbonitrile, Glutamate receptor 2, ZINC ION
著者Ahmed, A.H, Oswald, R.E.
登録日2011-08-03
公開日2011-08-17
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.975 Å)
主引用文献Mechanism of AMPA Receptor Activation by Partial Agonists: DISULFIDE TRAPPING OF CLOSED LOBE CONFORMATIONS.
J.Biol.Chem., 286, 2011
3T9X
DownloadVisualize
BU of 3t9x by Molmil
Glutamate bound to a double cysteine mutant (V484C/E657C) of the ligand binding domain of GluA2
分子名称: GLUTAMIC ACID, Glutamate receptor 2, ZINC ION
著者Ahmed, A.H, Oswald, R.E.
登録日2011-08-03
公開日2011-08-17
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.823 Å)
主引用文献Mechanism of AMPA Receptor Activation by Partial Agonists: DISULFIDE TRAPPING OF CLOSED LOBE CONFORMATIONS.
J.Biol.Chem., 286, 2011
3T96
DownloadVisualize
BU of 3t96 by Molmil
Iodowillardiine bound to a double cysteine mutant (A452C/S652C) of the ligand binding domain of GluA2
分子名称: 2-AMINO-3-(5-IODO-2,4-DIOXO-3,4-DIHYDRO-2H-PYRIMIDIN-1-YL)-PROPIONIC ACID, Glutamate receptor 2, ZINC ION
著者Ahmed, A.H, Wang, S, Chuang, H.H, Oswald, R.E.
登録日2011-08-02
公開日2011-08-17
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.872 Å)
主引用文献Mechanism of AMPA Receptor Activation by Partial Agonists: DISULFIDE TRAPPING OF CLOSED LOBE CONFORMATIONS.
J.Biol.Chem., 286, 2011
3LSL
DownloadVisualize
BU of 3lsl by Molmil
Piracetam bound to the ligand binding domain of GluA2 (flop form)
分子名称: 2-(2-oxopyrrolidin-1-yl)acetamide, GLUTAMIC ACID, Glutamate receptor 2, ...
著者Ahmed, A.H, Oswald, R.E.
登録日2010-02-12
公開日2010-03-16
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.122 Å)
主引用文献Piracetam Defines a New Binding Site for Allosteric Modulators of alpha-Amino-3-hydroxy-5-methyl-4-isoxazole-propionic Acid (AMPA) Receptors.
J.Med.Chem., 53, 2010
3DP6
DownloadVisualize
BU of 3dp6 by Molmil
Crystal structure of the binding domain of the AMPA subunit GluR2 bound to glutamate
分子名称: GLUTAMIC ACID, Glutamate receptor 2, ZINC ION
著者Ahmed, A.H, Wang, Q, Sondermann, H, Oswald, R.E.
登録日2008-07-07
公開日2008-11-25
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Structure of the S1S2 glutamate binding domain of GLuR3.
Proteins, 75, 2008
3DP4
DownloadVisualize
BU of 3dp4 by Molmil
Crystal structure of the binding domain of the AMPA subunit GluR3 bound to AMPA
分子名称: (S)-ALPHA-AMINO-3-HYDROXY-5-METHYL-4-ISOXAZOLEPROPIONIC ACID, Glutamate receptor 3, ZINC ION
著者Ahmed, A.H, Wang, Q, Sondermann, H, Oswald, R.E.
登録日2008-07-07
公開日2008-11-25
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (2.11 Å)
主引用文献Structure of the S1S2 glutamate binding domain of GLuR3.
Proteins, 75, 2008
3LSW
DownloadVisualize
BU of 3lsw by Molmil
Aniracetam bound to the ligand binding domain of GluA3
分子名称: 1-(4-METHOXYBENZOYL)-2-PYRROLIDINONE, GLUTAMIC ACID, GluA2 S1S2 domain, ...
著者Ahmed, A.H, Oswald, R.E.
登録日2010-02-13
公開日2010-03-16
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.752 Å)
主引用文献Piracetam Defines a New Binding Site for Allosteric Modulators of alpha-Amino-3-hydroxy-5-methyl-4-isoxazole-propionic Acid (AMPA) Receptors.
J.Med.Chem., 53, 2010
3LSX
DownloadVisualize
BU of 3lsx by Molmil
Piracetam bound to the ligand binding domain of GluA3
分子名称: 2-(2-oxopyrrolidin-1-yl)acetamide, GLUTAMIC ACID, GluA3 S1S2 domain, ...
著者Ahmed, A.H, Oswald, R.E.
登録日2010-02-13
公開日2011-03-16
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.006 Å)
主引用文献Piracetam Defines a New Binding Site for Allosteric Modulators of alpha-Amino-3-hydroxy-5-methyl-4-isoxazole-propionic Acid (AMPA) Receptors.
J.Med.Chem., 53, 2010
3LSF
DownloadVisualize
BU of 3lsf by Molmil
Piracetam bound to the ligand binding domain of GluA2
分子名称: 2-(2-oxopyrrolidin-1-yl)acetamide, GLUTAMIC ACID, Glutamate receptor 2, ...
著者Ahmed, A.H, Ptak, C.P, Oswald, R.E.
登録日2010-02-12
公開日2010-03-16
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.851 Å)
主引用文献Piracetam Defines a New Binding Site for Allosteric Modulators of alpha-Amino-3-hydroxy-5-methyl-4-isoxazole-propionic Acid (AMPA) Receptors.
J.Med.Chem., 53, 2010
3M3F
DownloadVisualize
BU of 3m3f by Molmil
PEPA bound to the ligand binding domain of GluA3 (flop form)
分子名称: 2-[2,6-difluoro-4-({2-[(phenylsulfonyl)amino]ethyl}sulfanyl)phenoxy]acetamide, GLUTAMIC ACID, Glutamate receptor 3, ...
著者Ahmed, A.H, Ptak, C.P, Oswald, R.E.
登録日2010-03-09
公開日2010-03-23
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Molecular mechanism of flop selectivity and subsite recognition for an AMPA receptor allosteric modulator: structures of GluA2 and GluA3 in complexes with PEPA.
Biochemistry, 49, 2010
3M3K
DownloadVisualize
BU of 3m3k by Molmil
Ligand binding domain (S1S2) of GluA3 (flop)
分子名称: GLUTAMIC ACID, Glutamate receptor 3, ZINC ION
著者Ahmed, A.H, Ptak, C.P, Oswald, R.E.
登録日2010-03-09
公開日2010-03-23
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.793 Å)
主引用文献Molecular mechanism of flop selectivity and subsite recognition for an AMPA receptor allosteric modulator: structures of GluA2 and GluA3 in complexes with PEPA.
Biochemistry, 49, 2010
3DLN
DownloadVisualize
BU of 3dln by Molmil
Crystal structure of the binding domain of the AMPA subunit GluR3 bound to glutamate
分子名称: GLUTAMIC ACID, Glutamate receptor 3, ZINC ION
著者Ahmed, A.H, Wang, Q, Sondermann, H, Oswald, R.E.
登録日2008-06-27
公開日2008-11-25
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.91 Å)
主引用文献Structure of the S1S2 glutamate binding domain of GLuR3.
Proteins, 75, 2008
3H03
DownloadVisualize
BU of 3h03 by Molmil
Crystal structure of the binding domain of the AMPA subunit GluR2 bound to UBP277
分子名称: 3-[3-(2-carboxyethyl)-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl]-L-alanine, Glutamate receptor 2, ZINC ION
著者Ahmed, A.H, Oswald, R.E.
登録日2009-04-08
公開日2009-05-05
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Mechanisms of antagonism of the GluR2 AMPA receptor: structure and dynamics of the complex of two willardiine antagonists with the glutamate binding domain.
Biochemistry, 48, 2009
3H06
DownloadVisualize
BU of 3h06 by Molmil
Crystal structure of the binding domain of the AMPA subunit GluR2 bound to the willardiine antagonist, UBP282
分子名称: 4-({3-[(2R)-2-amino-2-carboxyethyl]-2,6-dioxo-3,6-dihydropyrimidin-1(2H)-yl}methyl)benzoic acid, Glutamate receptor 2
著者Ahmed, A.H, Oswald, R.E.
登録日2009-04-08
公開日2009-05-05
最終更新日2017-08-23
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Mechanisms of antagonism of the GluR2 AMPA receptor: structure and dynamics of the complex of two willardiine antagonists with the glutamate binding domain.
Biochemistry, 48, 2009
3IL1
DownloadVisualize
BU of 3il1 by Molmil
Crystal structure of the AMPA subunit GluR2 bound to the allosteric modulator, IDRA-21
分子名称: (3S)-7-chloro-3-methyl-3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-dioxide, GLUTAMIC ACID, Glutamate receptor 2, ...
著者Ahmed, A.H, Ptak, C.P, Oswald, R.E.
登録日2009-08-06
公開日2009-09-15
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.998 Å)
主引用文献Probing the allosteric modulator binding site of GluR2 with thiazide derivatives
Biochemistry, 48, 2009
3ILT
DownloadVisualize
BU of 3ilt by Molmil
Crystal structure of the AMPA subunit GluR2 bound to the allosteric modulator, trichlormethiazide
分子名称: 6-CHLORO-3-(DICHLOROMETHYL)-3,4-DIHYDRO-2H-1,2,4-BENZOTHIADIAZINE-7-SULFONAMIDE 1,1-DIOXIDE, GLUTAMIC ACID, Glutamate receptor 2, ...
著者Ahmed, A.H, Ptak, C.P, Oswald, R.E.
登録日2009-08-07
公開日2009-09-15
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.107 Å)
主引用文献Probing the allosteric modulator binding site of GluR2 with thiazide derivatives
Biochemistry, 48, 2009
3T93
DownloadVisualize
BU of 3t93 by Molmil
Glutamate bound to a double cysteine mutant (A452C/S652C) of the ligand binding domain of GluA2
分子名称: GLUTAMIC ACID, Glutamate receptor 2, ZINC ION
著者Ahmed, A.H, Oswald, R.E.
登録日2011-08-02
公開日2011-08-17
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.907 Å)
主引用文献Mechanism of AMPA Receptor Activation by Partial Agonists: DISULFIDE TRAPPING OF CLOSED LOBE CONFORMATIONS.
J.Biol.Chem., 286, 2011
3ILU
DownloadVisualize
BU of 3ilu by Molmil
Crystal structure of the AMPA subunit GluR2 bound to the allosteric modulator, hydroflumethiazide
分子名称: 6-(trifluoromethyl)-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide, GLUTAMIC ACID, Glutamate receptor 2, ...
著者Ahmed, A.H, Ptak, C.P, Oswald, R.E.
登録日2009-08-07
公開日2009-09-15
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.003 Å)
主引用文献Probing the allosteric modulator binding site of GluR2 with thiazide derivatives
Biochemistry, 48, 2009
3T9U
DownloadVisualize
BU of 3t9u by Molmil
CNQX bound to an oxidized double cysteine mutant (A452C/S652C) of the ligand binding domain of GluA2
分子名称: 7-nitro-2,3-dioxo-2,3-dihydroquinoxaline-6-carbonitrile, Glutamate receptor 2, ZINC ION
著者Ahmed, A.H, Oswald, R.E.
登録日2011-08-03
公開日2011-08-17
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.97 Å)
主引用文献Mechanism of AMPA Receptor Activation by Partial Agonists: DISULFIDE TRAPPING OF CLOSED LOBE CONFORMATIONS.
J.Biol.Chem., 286, 2011
3T9H
DownloadVisualize
BU of 3t9h by Molmil
Kainate bound to a double cysteine mutant (A452C/S652C) of the ligand binding domain of GluA2
分子名称: 3-(CARBOXYMETHYL)-4-ISOPROPENYLPROLINE, Glutamate receptor 2, ZINC ION
著者Ahmed, A.H, Wang, S, Chuang, H.H, Oswald, R.E.
登録日2011-08-02
公開日2011-08-17
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.015 Å)
主引用文献Mechanism of AMPA Receptor Activation by Partial Agonists: DISULFIDE TRAPPING OF CLOSED LOBE CONFORMATIONS.
J.Biol.Chem., 286, 2011
5D6D
DownloadVisualize
BU of 5d6d by Molmil
Crystal structure of GASDALIE IgG1 Fc in complex with FcgRIIIa
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Ig gamma-1 chain C region, Low affinity immunoglobulin gamma Fc region receptor III-A, ...
著者Ahmed, A.A, Bjorkman, P.J.
登録日2015-08-12
公開日2016-02-10
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.13 Å)
主引用文献Structural characterization of GASDALIE Fc bound to the activating Fc receptor Fc gamma RIIIa.
J.Struct.Biol., 194, 2016
5D4Q
DownloadVisualize
BU of 5d4q by Molmil
Crystal structure of GASDALIE IgG1 Fc
分子名称: Ig gamma-1 chain C region, alpha-L-fucopyranose, beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
著者Ahmed, A.A, Bjorkman, P.J.
登録日2015-08-08
公開日2016-02-10
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.39 Å)
主引用文献Structural characterization of GASDALIE Fc bound to the activating Fc receptor Fc gamma RIIIa.
J.Struct.Biol., 194, 2016
4Q6Y
DownloadVisualize
BU of 4q6y by Molmil
Crystal structure of a chemoenzymatic glycoengineered disialylated Fc (di-sFc)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Ig gamma-1 chain C region, N-acetyl-alpha-neuraminic acid-(2-6)-beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Ahmed, A.A, Giddens, J, Pincetic, A, Lomino, J.V, Ravetch, J.V, Wang, L.X, Bjorkman, P.J.
登録日2014-04-23
公開日2014-07-23
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural characterization of anti-inflammatory immunoglobulin g fc proteins.
J.Mol.Biol., 426, 2014
4Q7D
DownloadVisualize
BU of 4q7d by Molmil
Wild type Fc (wtFc)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Ig gamma-1 chain C region
著者Ahmed, A.A, Giddens, J, Pincetic, A, Lomino, J.V, Ravetch, J.V, Wang, L.X, Bjorkman, P.J.
登録日2014-04-24
公開日2014-07-23
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Structural characterization of anti-inflammatory immunoglobulin g fc proteins.
J.Mol.Biol., 426, 2014
4F29
DownloadVisualize
BU of 4f29 by Molmil
Quisqualate bound to the ligand binding domain of GluA3i
分子名称: (S)-2-AMINO-3-(3,5-DIOXO-[1,2,4]OXADIAZOLIDIN-2-YL)-PROPIONIC ACID, Glutamate receptor 3, ZINC ION
著者Ahmed, A.H, Oswald, R.E.
登録日2012-05-07
公開日2012-05-16
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.749 Å)
主引用文献The loss of an electrostatic contact unique to AMPA receptor ligand binding domain 2 slows channel activation.
Biochemistry, 51, 2012

 

12>

225946

件を2024-10-09に公開中

PDB statisticsPDBj update infoContact PDBjnumon