3S9K
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3s9k by Molmil](/molmil-images/mine/3s9k) | Crystal structure of the Itk SH2 domain. | 分子名称: | CITRIC ACID, Tyrosine-protein kinase ITK/TSK | 著者 | Joseph, R.E, Ginder, N.D, Hoy, J.A, Nix, J.C, Fulton, B.D, Honzatko, R.B, Andreotti, A.H. | 登録日 | 2011-06-01 | 公開日 | 2012-02-08 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.354 Å) | 主引用文献 | Structure of the interleukin-2 tyrosine kinase Src homology 2 domain; comparison between X-ray and NMR-derived structures. Acta Crystallogr.,Sect.F, 68, 2012
|
|
3U8K
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3u8k by Molmil](/molmil-images/mine/3u8k) | Crystal structure of the acetylcholine binding protein (AChBP) from Lymnaea stagnalis in complex with NS3573 (1-(5-ethoxypyridin-3-yl)-1,4-diazepane) | 分子名称: | 1-(5-ethoxypyridin-3-yl)-1,4-diazepane, 2-acetamido-2-deoxy-beta-D-glucopyranose, Acetylcholine-binding protein, ... | 著者 | Rohde, L.A.H, Ahring, P.K, Jensen, M.L, Nielsen, E.O, Peters, D, Helgstrand, C, Krintel, C, Harpsoe, K, Gajhede, M, Kastrup, J.S, Balle, T. | 登録日 | 2011-10-17 | 公開日 | 2011-12-14 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.47 Å) | 主引用文献 | Intersubunit bridge formation governs agonist efficacy at nicotinic acetylcholine alpha 4 beta 2 receptors: unique role of halogen bonding revealed. J.Biol.Chem., 287, 2012
|
|
3U7C
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3u7c by Molmil](/molmil-images/mine/3u7c) | crystal structure of the V143I mutant of human carbonic anhydrase II | 分子名称: | BICARBONATE ION, CARBON DIOXIDE, Carbonic anhydrase 2, ... | 著者 | West, D.M, Kim, C.U, Robbins, A.H, Mckenna, R. | 登録日 | 2011-10-13 | 公開日 | 2013-02-13 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (0.93 Å) | 主引用文献 | crystal structure of the V143I mutant of human carbonic anhydrase II To be Published
|
|
2ZCM
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2zcm by Molmil](/molmil-images/mine/2zcm) | Crystal structure of IcaR, a repressor of the TetR family | 分子名称: | Biofilm operon icaABCD HTH-type negative transcriptional regulator icaR | 著者 | Jeng, W.Y, Ko, T.P, Liu, C.I, Guo, R.T, Shr, H.L, Wang, A.H.J. | 登録日 | 2007-11-10 | 公開日 | 2008-02-05 | 最終更新日 | 2021-11-10 | 実験手法 | X-RAY DIFFRACTION (1.33 Å) | 主引用文献 | Crystal structure of IcaR, a repressor of the TetR family implicated in biofilm formation in Staphylococcus epidermidis Nucleic Acids Res., 36, 2008
|
|
3SXU
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3sxu by Molmil](/molmil-images/mine/3sxu) | |
2Z4X
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2z4x by Molmil](/molmil-images/mine/2z4x) | S. cerevisiae geranylgeranyl pyrophosphate synthase in complex with magnesium and BPH-252 (P21) | 分子名称: | (1-HYDROXYNONANE-1,1-DIYL)BIS(PHOSPHONIC ACID), Geranylgeranyl pyrophosphate synthetase, MAGNESIUM ION | 著者 | Guo, R.T, Chen, C.K.-M, Hudock, M, Cao, R, Oldfield, E, Wang, A.H.-J. | 登録日 | 2007-06-26 | 公開日 | 2008-07-01 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Inhibition of geranylgeranyl diphosphate synthase by bisphosphonates: a crystallographic and computational investigation J.Med.Chem., 51, 2008
|
|
2Z7I
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2z7i by Molmil](/molmil-images/mine/2z7i) | S. cerevisiae geranylgeranyl pyrophosphate synthase in complex with inhibitor BPH-742 | 分子名称: | (2,2-DIPHOSPHONOETHYL)(DODECYL)DIMETHYLPHOSPHONIUM, Geranylgeranyl pyrophosphate synthetase, MAGNESIUM ION | 著者 | Guo, R.T, Chen, C.K.-M, Ko, T.-P, Cao, R, Hudock, M, Oldfield, E, Wang, A.H.-J. | 登録日 | 2007-08-23 | 公開日 | 2008-07-08 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Inhibition of geranylgeranyl diphosphate synthase by bisphosphonates: a crystallographic and computational investigation J.Med.Chem., 51, 2008
|
|
2Z4W
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2z4w by Molmil](/molmil-images/mine/2z4w) | S. cerevisiae geranylgeranyl pyrophosphate synthase in complex with magnesium and BPH-749 | 分子名称: | Geranylgeranyl pyrophosphate synthetase, MAGNESIUM ION, [(6E,11E)-2,6,12,16-tetramethylheptadeca-2,6,11,15-tetraene-9,9-diyl]bis(phosphonic acid) | 著者 | Chen, C.K.-M, Guo, R.T, Hudock, M, Cao, R, Oldfield, E, Wang, A.H.-J. | 登録日 | 2007-06-26 | 公開日 | 2008-07-01 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | 主引用文献 | Inhibition of geranylgeranyl diphosphate synthase by bisphosphonates: a crystallographic and computational investigation J.Med.Chem., 51, 2008
|
|
2ZB3
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2zb3 by Molmil](/molmil-images/mine/2zb3) | Crystal structure of mouse 15-ketoprostaglandin delta-13-reductase in complex with NADPH | 分子名称: | NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Prostaglandin reductase 2 | 著者 | Wu, Y.H, Wang, A.H.J, Ko, T.P, Guo, R.T, Hu, S.M, Chuang, L.M. | 登録日 | 2007-10-16 | 公開日 | 2008-09-30 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structural basis for catalytic and inhibitory mechanisms of human prostaglandin reductase PTGR2. Structure, 16, 2008
|
|
2ZCN
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2zcn by Molmil](/molmil-images/mine/2zcn) | Crystal structure of IcaR, a repressor of the TetR family | 分子名称: | Biofilm operon icaABCD HTH-type negative transcriptional regulator icaR | 著者 | Jeng, W.Y, Ko, T.P, Liu, C.I, Guo, R.T, Liu, C.L, Wang, A.H.J. | 登録日 | 2007-11-10 | 公開日 | 2008-02-05 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Crystal structure of IcaR, a repressor of the TetR family implicated in biofilm formation in Staphylococcus epidermidis Nucleic Acids Res., 36, 2008
|
|
2ZB8
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2zb8 by Molmil](/molmil-images/mine/2zb8) | Crystal structure of human 15-ketoprostaglandin delta-13-reductase in complex with NADP and indomethacin | 分子名称: | INDOMETHACIN, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Prostaglandin reductase 2, ... | 著者 | Wu, Y.H, Wang, A.H.J, Ko, T.P, Guo, R.T, Hu, S.M, Chuang, L.M. | 登録日 | 2007-10-16 | 公開日 | 2008-09-30 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structural basis for catalytic and inhibitory mechanisms of human prostaglandin reductase PTGR2. Structure, 16, 2008
|
|
3T9V
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3t9v by Molmil](/molmil-images/mine/3t9v) | |
3SH3
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3sh3 by Molmil](/molmil-images/mine/3sh3) | Crystal structure of a pro-inflammatory lectin from the seeds of Dioclea wilsonii STANDL | 分子名称: | 5-bromo-4-chloro-1H-indol-3-yl alpha-D-mannopyranoside, CALCIUM ION, CHLORIDE ION, ... | 著者 | Rangel, T.B.A, Rocha, B.A.M, Bezerra, G.A, Bezerra, M.J.B, Nascimento, K.S, Nagano, C.S, Sampaio, A.H, Assreuy, A.M.S, Gruber, K, Delatorre, P, Cavada, B.S. | 登録日 | 2011-06-15 | 公開日 | 2011-10-05 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Crystal structure of a pro-inflammatory lectin from the seeds of Dioclea wilsonii Standl. Biochimie, 94, 2012
|
|
3T7H
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3t7h by Molmil](/molmil-images/mine/3t7h) | Atg8 transfer from Atg7 to Atg3: a distinctive E1-E2 architecture and mechanism in the autophagy pathway | 分子名称: | Ubiquitin-like modifier-activating enzyme ATG7 | 著者 | Taherbhoy, A.M, Tait, S.W, Kaiser, S.E, Williams, A.H, Deng, A, Nourse, A, Hammel, M, Kurinov, I, Rock, C.O, Green, D.R, Schulman, B.A. | 登録日 | 2011-07-30 | 公開日 | 2011-11-23 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Atg8 transfer from atg7 to atg3: a distinctive e1-e2 architecture and mechanism in the autophagy pathway. Mol.Cell, 44, 2011
|
|
3T7F
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3t7f by Molmil](/molmil-images/mine/3t7f) | Atg8 transfer from Atg7 to Atg3: a distinctive E1-E2 architecture and mechanism in the autophagy pathway | 分子名称: | Ubiquitin-like modifier-activating enzyme ATG7 | 著者 | Taherbhoy, A.M, Tait, S.W, Kaiser, S.E, Williams, A.H, Deng, A, Nourse, A, Hammel, M, Kurinov, I, Rock, C.O, Green, D.R, Schulman, B.A. | 登録日 | 2011-07-30 | 公開日 | 2011-11-23 | 実験手法 | X-RAY DIFFRACTION (1.89 Å) | 主引用文献 | Atg8 transfer from atg7 to atg3: a distinctive e1-e2 architecture and mechanism in the autophagy pathway. Mol.Cell, 44, 2011
|
|
3TG7
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3tg7 by Molmil](/molmil-images/mine/3tg7) | Crystal structure of Adenovirus serotype 5 hexon at 1.6A resolution | 分子名称: | Hexon protein | 著者 | Zhu, Y, Roszak, A.W, Isaacs, N.W, McVey, J.H, Nicklin, S.A, Baker, A.H. | 登録日 | 2011-08-17 | 公開日 | 2011-11-02 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.57 Å) | 主引用文献 | crystal structure of Adenovirus serotype 5 hexon at 1.6A resolution To be Published
|
|
3T9U
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3t9u by Molmil](/molmil-images/mine/3t9u) | |
3U8N
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3u8n by Molmil](/molmil-images/mine/3u8n) | Crystal structure of the acetylcholine binding protein (AChBP) from Lymnaea stagnalis in complex with NS3950 (1-(6-bromo-5-ethoxypyridin-3-yl)-1,4-diazepane) | 分子名称: | 1-(6-bromo-5-ethoxypyridin-3-yl)-1,4-diazepane, 2-acetamido-2-deoxy-beta-D-glucopyranose, Acetylcholine-binding protein, ... | 著者 | Rohde, L.A.H, Ahring, P.K, Jensen, M.L, Nielsen, E.O, Peters, D, Helgstrand, C, Krintel, C, Harpsoe, K, Gajhede, M, Kastrup, J.S, Balle, T. | 登録日 | 2011-10-17 | 公開日 | 2011-12-14 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | Intersubunit bridge formation governs agonist efficacy at nicotinic acetylcholine alpha 4 beta 2 receptors: unique role of halogen bonding revealed. J.Biol.Chem., 287, 2012
|
|
2ZX5
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2zx5 by Molmil](/molmil-images/mine/2zx5) | alpha-L-fucosidase complexed with inhibitor, F10 | 分子名称: | 3-(1H-indol-3-yl)-N-{[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methylpiperidin-2-yl]methyl}propanamide, Alpha-L-fucosidase, putative | 著者 | Wu, H.-J, Ko, T.-P, Ho, C.-W, Lin, C.-H, Wang, A.H.-J. | 登録日 | 2008-12-19 | 公開日 | 2009-12-08 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | 主引用文献 | Structural basis of alpha-fucosidase inhibition by iminocyclitols with K(i) values in the micro- to picomolar range. Angew.Chem.Int.Ed.Engl., 49, 2010
|
|
3A2Z
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3a2z by Molmil](/molmil-images/mine/3a2z) | E. coli Gsp amidase Cys59 sulfenic acid | 分子名称: | Bifunctional glutathionylspermidine synthetase/amidase | 著者 | Pai, C.-H, Ko, T.-P, Chiang, B.-Y, Lin, C.-H, Wang, A.H.-J. | 登録日 | 2009-06-05 | 公開日 | 2010-05-19 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Protein S-thiolation by Glutathionylspermidine (Gsp): the role of Escherichia coli Gsp synthetASE/amidase in redox regulation J.Biol.Chem., 285, 2010
|
|
3A2Y
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3a2y by Molmil](/molmil-images/mine/3a2y) | E. coli Gsp amidase C59A complexed with Gsp | 分子名称: | Bifunctional glutathionylspermidine synthetase/amidase, GLUTATHIONYLSPERMIDINE | 著者 | Pai, C.-H, Ko, T.-P, Chiang, B.-Y, Lin, C.-H, Wang, A.H.-J. | 登録日 | 2009-06-04 | 公開日 | 2010-05-19 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Structure and mechanism of Escherichia coli glutathionylspermidine amidase belonging to the family of cysteine; histidine-dependent amidohydrolases/peptidases Protein Sci., 20, 2011
|
|
3ADZ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3adz by Molmil](/molmil-images/mine/3adz) | Crystal structure of the C(30) carotenoid dehydrosqualene synthase from Staphylococcus aureus complexed with intermediate PSPP | 分子名称: | Dehydrosqualene synthase, MAGNESIUM ION, {(1R,2R,3R)-2-[(3E)-4,8-dimethylnona-3,7-dien-1-yl]-2-methyl-3-[(1E,5E)-2,6,10-trimethylundeca-1,5,9-trien-1-yl]cyclopropyl}methyl trihydrogen diphosphate | 著者 | Liu, C.I, Jeng, W.Y, Wang, A.H.J, Oldfield, E. | 登録日 | 2010-01-31 | 公開日 | 2010-11-24 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.89 Å) | 主引用文献 | Mechanism of action and inhibition of dehydrosqualene synthase. Proc.Natl.Acad.Sci.USA, 107, 2010
|
|
2ZWZ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2zwz by Molmil](/molmil-images/mine/2zwz) | alpha-L-fucosidase complexed with inhibitor, Core1 | 分子名称: | (2R,3R,4R,5R,6S)-2-(aminomethyl)-6-methylpiperidine-3,4,5-triol, Alpha-L-fucosidase, putative | 著者 | Wu, H.-J, Ko, T.-P, Ho, C.-W, Lin, C.-H, Wang, A.H.-J. | 登録日 | 2008-12-19 | 公開日 | 2009-12-08 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.36 Å) | 主引用文献 | Structural basis of alpha-fucosidase inhibition by iminocyclitols with K(i) values in the micro- to picomolar range. Angew.Chem.Int.Ed.Engl., 49, 2010
|
|
2ZXD
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2zxd by Molmil](/molmil-images/mine/2zxd) | alpha-L-fucosidase complexed with inhibitor, iso-6FNJ | 分子名称: | (2S,3R,4S,5R)-2-(1-methylethyl)piperidine-3,4,5-triol, Alpha-L-fucosidase, putative | 著者 | Wu, H.-J, Ko, T.-P, Ho, C.-W, Lin, C.-H, Wang, A.H.-J. | 登録日 | 2008-12-22 | 公開日 | 2009-12-08 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | Structural basis of alpha-fucosidase inhibition by iminocyclitols with K(i) values in the micro- to picomolar range. Angew.Chem.Int.Ed.Engl., 49, 2010
|
|
2ZY5
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2zy5 by Molmil](/molmil-images/mine/2zy5) | R487A mutant of L-aspartate beta-decarboxylase | 分子名称: | L-aspartate beta-decarboxylase, PYRIDOXAL-5'-PHOSPHATE | 著者 | Chen, H.-J, Ko, T.-P, Lee, C.-Y, Wang, N.-C, Wang, A.H.-J. | 登録日 | 2009-01-13 | 公開日 | 2009-01-27 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | 主引用文献 | Structure, Assembly, and Mechanism of a PLP-Dependent Dodecameric l-Aspartate beta-Decarboxylase Structure, 17, 2009
|
|