4R3P
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![BU of 4r3p by Molmil](/molmil-images/mine/4r3p) | Crystal structures of EGFR in complex with Mig6 | 分子名称: | Epidermal growth factor receptor, peptide from ERBB receptor feedback inhibitor 1 | 著者 | Park, E, Kim, N, Yi, Z, Cho, A, Kim, K, Ficarro, S.B, Park, A, Park, W.Y, Murray, B, Meyerson, M, Beroukim, R, Marto, J.A, Cho, J, Eck, M.J. | 登録日 | 2014-08-17 | 公開日 | 2015-08-12 | 最終更新日 | 2015-09-16 | 実験手法 | X-RAY DIFFRACTION (2.905 Å) | 主引用文献 | Structure and mechanism of activity-based inhibition of the EGF receptor by Mig6. Nat.Struct.Mol.Biol., 22, 2015
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5JG9
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6SHL
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![BU of 6shl by Molmil](/molmil-images/mine/6shl) | Structure of a marine algae virus of the order Picornavirales | 分子名称: | VP1, VP2, VP3, ... | 著者 | Munke, A, Tomaru, Y, Kimura, K, Okamoto, K. | 登録日 | 2019-08-07 | 公開日 | 2020-02-12 | 最終更新日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Capsid Structure of a Marine Algal Virus of the Order Picornavirales . J.Virol., 94, 2020
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8GSK
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8DNF
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![BU of 8dnf by Molmil](/molmil-images/mine/8dnf) | Cryo-EM structure of nonmuscle gamma-actin | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Actin, cytoplasmic 2, ... | 著者 | Arora, A.S, Huang, H.L, Heissler, S.M, Chinthalapudi, K. | 登録日 | 2022-07-11 | 公開日 | 2023-04-12 | 実験手法 | ELECTRON MICROSCOPY (3.38 Å) | 主引用文献 | Structural insights into actin isoforms. Elife, 12, 2023
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5J8D
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![BU of 5j8d by Molmil](/molmil-images/mine/5j8d) | Structure of nitroreductase from E. cloacae complexed with nicotinic acid adenine dinucleotide | 分子名称: | FLAVIN MONONUCLEOTIDE, NICOTINIC ACID ADENINE DINUCLEOTIDE, Oxygen-insensitive NAD(P)H nitroreductase | 著者 | Haynes, C.A, Koder, R.L, Miller, A.F, Rodgers, D.W. | 登録日 | 2016-04-07 | 公開日 | 2017-05-17 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Mechanism-Informed Refinement Reveals Altered Substrate-Binding Mode for Catalytically Competent Nitroreductase. Structure, 25, 2017
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6SI2
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![BU of 6si2 by Molmil](/molmil-images/mine/6si2) | p53 cancer mutant Y220S | 分子名称: | 1,2-ETHANEDIOL, Cellular tumor antigen p53, GLYCEROL, ... | 著者 | Joerger, A.C, Bauer, M.R, Structural Genomics Consortium (SGC) | 登録日 | 2019-08-08 | 公開日 | 2020-02-19 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Targeting Cavity-Creating p53 Cancer Mutations with Small-Molecule Stabilizers: the Y220X Paradigm. Acs Chem.Biol., 15, 2020
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7M1D
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7M7X
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8DNH
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![BU of 8dnh by Molmil](/molmil-images/mine/8dnh) | Cryo-EM structure of nonmuscle beta-actin | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Actin, cytoplasmic 1, ... | 著者 | Arora, A.S, Huang, H.L, Heissler, S.M, Chinthalapudi, K. | 登録日 | 2022-07-11 | 公開日 | 2023-04-12 | 実験手法 | ELECTRON MICROSCOPY (2.99 Å) | 主引用文献 | Structural insights into actin isoforms. Elife, 12, 2023
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6SE9
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![BU of 6se9 by Molmil](/molmil-images/mine/6se9) | Cold-adapted beta-D-galactosidase from Arthrobacter sp. 32cB mutant E441Q in complex with lactose bound in shallow mode | 分子名称: | ACETATE ION, Beta-galactosidase, FORMIC ACID, ... | 著者 | Rutkiewicz, M, Bujacz, A, Bujacz, G. | 登録日 | 2019-07-29 | 公開日 | 2019-09-11 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.965 Å) | 主引用文献 | Active Site Architecture and Reaction Mechanism Determination of Cold Adapted beta-d-galactosidase fromArthrobactersp. 32cB. Int J Mol Sci, 20, 2019
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6AXT
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6AZU
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![BU of 6azu by Molmil](/molmil-images/mine/6azu) | Holo IDO1 crystal structure | 分子名称: | Indoleamine 2,3-dioxygenase 1, PROTOPORPHYRIN IX CONTAINING FE, SULFATE ION | 著者 | Lewis, H.A, Yan, C. | 登録日 | 2017-09-13 | 公開日 | 2018-03-21 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.822 Å) | 主引用文献 | Immune-modulating enzyme indoleamine 2,3-dioxygenase is effectively inhibited by targeting its apo-form. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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6AY9
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![BU of 6ay9 by Molmil](/molmil-images/mine/6ay9) | Structure of the native full-length HIV-1 capsid protein in complex with CPSF6 peptide | 分子名称: | CHLORIDE ION, Cleavage and polyadenylation specificity factor subunit 6, HIV-1 capsid protein, ... | 著者 | Gres, A.T, Kirby, K.A, Sarafianos, S.G. | 登録日 | 2017-09-07 | 公開日 | 2018-09-12 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Multidisciplinary studies with mutated HIV-1 capsid proteins reveal structural mechanisms of lattice stabilization. Nat Commun, 14, 2023
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6F1T
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![BU of 6f1t by Molmil](/molmil-images/mine/6f1t) | Cryo-EM structure of two dynein tail domains bound to dynactin and BICDR1 | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ARP1 actin related protein 1 homolog A, ... | 著者 | Urnavicius, L, Lau, C.K, Elshenawy, M.M, Morales-Rios, E, Motz, C, Yildiz, A, Carter, A.P. | 登録日 | 2017-11-23 | 公開日 | 2018-01-17 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Cryo-EM shows how dynactin recruits two dyneins for faster movement. Nature, 554, 2018
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6EV3
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![BU of 6ev3 by Molmil](/molmil-images/mine/6ev3) | Structure of wild type A. niger Fdc1 that has been illuminated with UV light, with prFMN in the iminium and ketimine form | 分子名称: | 1-deoxy-5-O-phosphono-1-(3,3,4,5-tetramethyl-9,11-dioxo-2,3,8,9,10,11-hexahydro-7H-quinolino[1,8-fg]pteridin-12-ium-7-y l)-D-ribitol, 1-deoxy-5-O-phosphono-1-[(10aR)-2,2,3,4-tetramethyl-8,10-dioxo-1,2,8,9,10,10a-hexahydro-6H-indeno[1,7-ef]pyrimido[4,5-b][1,4]diazepin-6-yl]-D-ribitol, Ferulic acid decarboxylase 1, ... | 著者 | Bailey, S.S, David, L, Payne, K.A.P. | 登録日 | 2017-11-01 | 公開日 | 2017-12-20 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | 主引用文献 | The role of conserved residues in Fdc decarboxylase in prenylated flavin mononucleotide oxidative maturation, cofactor isomerization, and catalysis. J. Biol. Chem., 293, 2018
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4RGK
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![BU of 4rgk by Molmil](/molmil-images/mine/4rgk) | Crystal Structure of Putative Phytanoyl-CoA Dioxygenase Family Protein YbiU from Yersinia pestis | 分子名称: | 1,2-ETHANEDIOL, GLYCEROL, SULFATE ION, ... | 著者 | Kim, Y, Chhor, G, Endres, M, Babnigg, G, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | 登録日 | 2014-09-30 | 公開日 | 2014-12-31 | 最終更新日 | 2017-11-22 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | Crystal Structure of Putative Phytanoyl-CoA Dioxygenase Family Protein YbiU from Yersinia pestis To be Published
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6EVB
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![BU of 6evb by Molmil](/molmil-images/mine/6evb) | Structure of E282Q A. niger Fdc1 with prFMN in the iminium form | 分子名称: | 1-deoxy-5-O-phosphono-1-(3,3,4,5-tetramethyl-9,11-dioxo-2,3,8,9,10,11-hexahydro-7H-quinolino[1,8-fg]pteridin-12-ium-7-y l)-D-ribitol, Ferulic acid decarboxylase 1, MANGANESE (II) ION, ... | 著者 | Bailey, S.S, Leys, D, Payne, K.A.P. | 登録日 | 2017-11-01 | 公開日 | 2017-12-20 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.13 Å) | 主引用文献 | The role of conserved residues in Fdc decarboxylase in prenylated flavin mononucleotide oxidative maturation, cofactor isomerization, and catalysis. J. Biol. Chem., 293, 2018
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7NG0
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![BU of 7ng0 by Molmil](/molmil-images/mine/7ng0) | Crystal structure of N- and C-terminally truncated Geobacillus thermoleovorans nucleoid occlusion protein Noc | 分子名称: | Nucleoid occlusion protein, SULFATE ION | 著者 | Jalal, A.S.B, Tran, N.T, Wu, L.J, Ramakrishnan, K, Rejzek, M, Stevenson, C.E.M, Lawson, D.M, Errington, J, Le, T.B.K. | 登録日 | 2021-02-08 | 公開日 | 2021-02-17 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | 主引用文献 | CTP regulates membrane-binding activity of the nucleoid occlusion protein Noc. Mol.Cell, 81, 2021
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7AH1
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![BU of 7ah1 by Molmil](/molmil-images/mine/7ah1) | L19 diabody fragment from immunocytokine L19-IL2 | 分子名称: | Anti-(ED-B) scFV | 著者 | Ongaro, T, Guarino, S.R, Scietti, L, Palamini, M, Wulhfard, S, Villa, A, Neri, D, Forneris, F. | 登録日 | 2020-09-23 | 公開日 | 2021-02-10 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Inference of molecular structure for characterization and improvement of clinical grade immunocytokines. J.Struct.Biol., 213, 2021
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6VBM
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![BU of 6vbm by Molmil](/molmil-images/mine/6vbm) | Crystal structure of a S310A mutant of PBP2 from Neisseria gonorrhoeae | 分子名称: | PHOSPHATE ION, Probable peptidoglycan D,D-transpeptidase PenA | 著者 | Singh, A, Davies, C. | 登録日 | 2019-12-19 | 公開日 | 2020-04-15 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.71 Å) | 主引用文献 | Mutations in Neisseria gonorrhoeae penicillin-binding protein 2 associated with extended-spectrum cephalosporin resistance create an energetic barrier against acylation via restriction of protein dynamics J.Biol.Chem., 2020
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4RGJ
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![BU of 4rgj by Molmil](/molmil-images/mine/4rgj) | Apo crystal structure of CDPK4 from Plasmodium falciparum, PF3D7_0717500 | 分子名称: | Calcium-dependent protein kinase 4 | 著者 | Wernimont, A.K, Walker, J.R, Hutchinson, A, Seitova, A, He, H, Loppnau, P, Neculai, M, Amani, M, Lin, Y.H, Ravichandran, M, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Hui, R, Lovato, D.V, Structural Genomics Consortium (SGC) | 登録日 | 2014-09-30 | 公開日 | 2014-10-29 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.303 Å) | 主引用文献 | Apo crystal structure of CDPK4 from Plasmodium falciparum, PF3D7_0717500 To be Published
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4REV
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![BU of 4rev by Molmil](/molmil-images/mine/4rev) | Structure of the dirigent protein DRR206 | 分子名称: | 2,3-DIMETHYLIMIDAZOLIUM ION, CHLORIDE ION, Disease resistance response protein 206, ... | 著者 | Kim, K.-Y, Smith, C.A, Merkley, E.D, Cort, J.R, Davin, L.B, Lewis, N.G. | 登録日 | 2014-09-24 | 公開日 | 2014-11-26 | 最終更新日 | 2015-02-18 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Trimeric Structure of (+)-Pinoresinol-forming Dirigent Protein at 1.95 angstrom Resolution with Three Isolated Active Sites. J.Biol.Chem., 290, 2015
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6EW7
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8V1J
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