6AZU
Holo IDO1 crystal structure
Summary for 6AZU
| Entry DOI | 10.2210/pdb6azu/pdb |
| Descriptor | Indoleamine 2,3-dioxygenase 1, PROTOPORPHYRIN IX CONTAINING FE, SULFATE ION (3 entities in total) |
| Functional Keywords | holoenzyme ido1, oxidoreductase |
| Biological source | Homo sapiens (Human) |
| Cellular location | Cytoplasm, cytosol : P14902 |
| Total number of polymer chains | 4 |
| Total formula weight | 183870.15 |
| Authors | Lewis, H.A.,Yan, C. (deposition date: 2017-09-13, release date: 2018-03-21, Last modification date: 2023-10-04) |
| Primary citation | Nelp, M.T.,Kates, P.A.,Hunt, J.T.,Newitt, J.A.,Balog, A.,Maley, D.,Zhu, X.,Abell, L.,Allentoff, A.,Borzilleri, R.,Lewis, H.A.,Lin, Z.,Seitz, S.P.,Yan, C.,Groves, J.T. Immune-modulating enzyme indoleamine 2,3-dioxygenase is effectively inhibited by targeting its apo-form. Proc. Natl. Acad. Sci. U.S.A., 115:3249-3254, 2018 Cited by PubMed: 29531094DOI: 10.1073/pnas.1719190115 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.822 Å) |
Structure validation
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