6FJ3
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![BU of 6fj3 by Molmil](/molmil-images/mine/6fj3) | High resolution crystal structure of parathyroid hormone 1 receptor in complex with a peptide agonist. | 分子名称: | ACETIC ACID, CHLORIDE ION, OLEIC ACID, ... | 著者 | Ehrenmann, J, Schoppe, J, Klenk, C, Rappas, M, Kummer, L, Dore, A.S, Pluckthun, A. | 登録日 | 2018-01-19 | 公開日 | 2018-11-21 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | High-resolution crystal structure of parathyroid hormone 1 receptor in complex with a peptide agonist. Nat. Struct. Mol. Biol., 25, 2018
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6ZIH
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8R16
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![BU of 8r16 by Molmil](/molmil-images/mine/8r16) | Structure of compound 12 bound to SARS-CoV-2 main protease | 分子名称: | 1,2-ETHANEDIOL, 1-[6,7-bis(chloranyl)-3,4-dihydro-1H-isoquinolin-2-yl]-2-(5-methylpyridin-3-yl)ethanone, 3C-like proteinase, ... | 著者 | Mac Sweeney, A, Hazemann, J. | 登録日 | 2023-11-01 | 公開日 | 2024-02-07 | 最終更新日 | 2024-07-03 | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | 主引用文献 | Identification of SARS-CoV-2 Mpro inhibitors through deep reinforcement learning for de novo drug design and computational chemistry approaches. Rsc Med Chem, 15, 2024
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6THA
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![BU of 6tha by Molmil](/molmil-images/mine/6tha) | Crystal structure of human sugar transporter GLUT1 (SLC2A1) in the inward conformation | 分子名称: | 3,6,9,12,15,18-HEXAOXAICOSANE-1,20-DIOL, CHLORIDE ION, Solute carrier family 2, ... | 著者 | Pedersen, B.P, Paulsen, P.A, Custodio, T.F. | 登録日 | 2019-11-19 | 公開日 | 2020-11-25 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structural comparison of GLUT1 to GLUT3 reveal transport regulation mechanism in sugar porter family. Life Sci Alliance, 4, 2021
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6ZJJ
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5NLH
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![BU of 5nlh by Molmil](/molmil-images/mine/5nlh) | Chicken GRIFIN (crystallisation pH: 8.5) | 分子名称: | Galectin, beta-D-galactopyranose-(1-4)-alpha-D-glucopyranose | 著者 | Ruiz, F.M, Romero, A. | 登録日 | 2017-04-04 | 公開日 | 2018-02-14 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.1 Å) | 主引用文献 | Chicken GRIFIN: Structural characterization in crystals and in solution. Biochimie, 146, 2018
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8UUK
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![BU of 8uuk by Molmil](/molmil-images/mine/8uuk) | Pendrin in apo | 分子名称: | 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, CHOLESTEROL, Lauryl Maltose Neopentyl Glycol, ... | 著者 | Wang, L, Hoang, A, Zhou, M. | 登録日 | 2023-11-01 | 公開日 | 2024-02-07 | 最終更新日 | 2024-02-28 | 実験手法 | ELECTRON MICROSCOPY (2.5 Å) | 主引用文献 | Mechanism of anion exchange and small-molecule inhibition of pendrin. Nat Commun, 15, 2024
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6GAE
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![BU of 6gae by Molmil](/molmil-images/mine/6gae) | BACTERIORHODOPSIN, 560 FS STATE, REAL-SPACE REFINED AGAINST 15% EXTRAPOLATED STRUCTURE FACTORS | 分子名称: | 2,3-DI-PHYTANYL-GLYCEROL, Bacteriorhodopsin, DECANE, ... | 著者 | Nass Kovacs, G, Colletier, J.-P, Gruenbein, M.L, Stensitzki, T, Batyuk, A, Carbajo, S, Doak, R.B, Ehrenberg, D, Foucar, L, Gasper, R, Gorel, A, Hilpert, M, Kloos, M, Koglin, J, Reinstein, J, Roome, C.M, Schlesinger, R, Seaberg, M, Shoeman, R.L, Stricker, M, Boutet, S, Haacke, S, Heberle, J, Domratcheva, T, Schlichting, I. | 登録日 | 2018-04-11 | 公開日 | 2019-04-24 | 最終更新日 | 2019-07-31 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Three-dimensional view of ultrafast dynamics in photoexcited bacteriorhodopsin. Nat Commun, 10, 2019
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6VJQ
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8U6X
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![BU of 8u6x by Molmil](/molmil-images/mine/8u6x) | ATP-dependent DNA ligase Lig E from Neisseria gonorrhoeae | 分子名称: | ADENOSINE MONOPHOSPHATE, DNA (5'-D(*AP*TP*TP*GP*CP*GP*AP*CP*CP*CP*CP*AP*CP*TP*AP*TP*CP*GP*GP*AP*A)-3'), DNA (5'-D(*TP*TP*CP*CP*GP*AP*TP*AP*GP*TP*GP*GP*GP*GP*TP*CP*GP*CP*AP*AP*T)-3'), ... | 著者 | Williamson, A, Pan, J. | 登録日 | 2023-09-14 | 公開日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.44 Å) | 主引用文献 | A role for the ATP-dependent DNA ligase lig E of Neisseria gonorrhoeae in biofilm formation. Bmc Microbiol., 24, 2024
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4WZ3
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![BU of 4wz3 by Molmil](/molmil-images/mine/4wz3) | Crystal structure of the complex between LubX/LegU2/Lpp2887 U-box 1 and Homo sapiens UBE2D2 | 分子名称: | E3 ubiquitin-protein ligase LubX, Ubiquitin-conjugating enzyme E2 D2 | 著者 | Stogios, P.J, Quaile, A.T, Skarina, T, Nocek, B, Di Leo, R, Yim, V, Savchenko, A, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | 登録日 | 2014-11-18 | 公開日 | 2015-01-07 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Molecular Characterization of LubX: Functional Divergence of the U-Box Fold by Legionella pneumophila. Structure, 23, 2015
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4WZD
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![BU of 4wzd by Molmil](/molmil-images/mine/4wzd) | Complex of 70S ribosome with cognate tRNA-Tyr in the P-site | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | 著者 | Rozov, A, Demeshkina, N, Yusupov, M, Yusupova, G. | 登録日 | 2014-11-19 | 公開日 | 2015-06-10 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Structural insights into the translational infidelity mechanism. Nat Commun, 6, 2015
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6TLR
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![BU of 6tlr by Molmil](/molmil-images/mine/6tlr) | HUMAN CK2 KINASE ALPHA SUBUNIT IN COMPLEX WITH THE ATP-COMPETITIVE INHIBITOR 4,7-DIBROMOBENZOTRIAZOLE | 分子名称: | 4,7-bis(bromanyl)-1~{H}-benzotriazole, CHLORIDE ION, Casein kinase II subunit alpha, ... | 著者 | Czapinska, H, Piasecka, A, Winiewska-Szajewska, M, Bochtler, M, Poznanski, J. | 登録日 | 2019-12-03 | 公開日 | 2020-12-16 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.64 Å) | 主引用文献 | Halogen Atoms in the Protein-Ligand System. Structural and Thermodynamic Studies of the Binding of Bromobenzotriazoles by the Catalytic Subunit of Human Protein Kinase CK2. J.Phys.Chem.B, 125, 2021
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8GDI
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![BU of 8gdi by Molmil](/molmil-images/mine/8gdi) | X-ray crystal structure of CYP124A1 from Mycobacterium Marinum in complex with 7-ketocholesterol | 分子名称: | (3beta,8alpha,9beta)-3-hydroxycholest-5-en-7-one, Cytochrome P450 124A1, PROTOPORPHYRIN IX CONTAINING FE | 著者 | Ghith, A, Bruning, J.B, Bell, S.G. | 登録日 | 2023-03-06 | 公開日 | 2023-05-24 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (1.81 Å) | 主引用文献 | The oxidation of cholesterol derivatives by the CYP124 and CYP142 enzymes from Mycobacterium marinum. J.Steroid Biochem.Mol.Biol., 231, 2023
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8GB7
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7PJB
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![BU of 7pjb by Molmil](/molmil-images/mine/7pjb) | Crystal structure of YTHDC1 with compound PSI_DC1_004 | 分子名称: | (R)-homoproline, GLYCEROL, SULFATE ION, ... | 著者 | Bedi, R.K, Huang, D, Caflisch, A. | 登録日 | 2021-08-23 | 公開日 | 2021-10-20 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structure-based design of ligands of the m6A-RNA reader YTHDC1 Eur J Med Chem Rep, 5, 2022
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6GB7
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![BU of 6gb7 by Molmil](/molmil-images/mine/6gb7) | Structure of H-2Db with scoop loop from tapasin | 分子名称: | Beta-2-microglobulin, GLY-GLY-LEU-SER, GLYCEROL, ... | 著者 | Hafstrand, I, Sandalova, T, Achour, A. | 登録日 | 2018-04-13 | 公開日 | 2019-03-06 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | Successive crystal structure snapshots suggest the basis for MHC class I peptide loading and editing by tapasin. Proc.Natl.Acad.Sci.USA, 116, 2019
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8QPD
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8GB8
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4X8B
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![BU of 4x8b by Molmil](/molmil-images/mine/4x8b) | Ergothioneine-biosynthetic sulfoxide synthase EgtB, apo form | 分子名称: | CALCIUM ION, CHLORIDE ION, FE (III) ION, ... | 著者 | Vit, A, Goncharenko, K.V, Blankenfeldt, W, Seebeck, F.P. | 登録日 | 2014-12-10 | 公開日 | 2015-01-28 | 最終更新日 | 2017-09-06 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Structure of the Sulfoxide Synthase EgtB from the Ergothioneine Biosynthetic Pathway. Angew.Chem.Int.Ed.Engl., 54, 2015
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8TYO
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6ZPG
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![BU of 6zpg by Molmil](/molmil-images/mine/6zpg) | Kinesin binding protein (KBP) | 分子名称: | KIF-binding protein | 著者 | Atherton, J, Hummel, J.J.A, Olieric, N, Locke, J, Pena, A, Rosenfeld, S.S, Steinmetz, M.O, Hoogenraad, C.C, Moores, C.A. | 登録日 | 2020-07-08 | 公開日 | 2020-12-30 | 最終更新日 | 2024-05-01 | 実験手法 | ELECTRON MICROSCOPY (4.6 Å) | 主引用文献 | The mechanism of kinesin inhibition by kinesin-binding protein. Elife, 9, 2020
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8A2C
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![BU of 8a2c by Molmil](/molmil-images/mine/8a2c) | The crystal structure of the S178A mutant of PET40, a PETase enzyme from an unclassified Amycolatopsis | 分子名称: | 1,2-ETHANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CHLORIDE ION, ... | 著者 | Costanzi, E, Applegate, V, Port, A, Smits, S.H.J. | 登録日 | 2022-06-03 | 公開日 | 2023-06-14 | 最終更新日 | 2024-06-26 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | The metagenome-derived esterase PET40 is highly promiscuous and hydrolyses polyethylene terephthalate (PET). Febs J., 291, 2024
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6WE6
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![BU of 6we6 by Molmil](/molmil-images/mine/6we6) | Camphor bound P450cam D251E structure | 分子名称: | CAMPHOR, Camphor 5-monooxygenase, POTASSIUM ION, ... | 著者 | Amaya, J.A, Poulos, T.L, Batabyal, D. | 登録日 | 2020-04-01 | 公開日 | 2020-07-08 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.16 Å) | 主引用文献 | Proton Relay Network in the Bacterial P450s: CYP101A1 and CYP101D1. Biochemistry, 59, 2020
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7PJ8
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