8B53
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6QVZ
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![BU of 6qvz by Molmil](/molmil-images/mine/6qvz) | The Transcriptional Regulator PrfA-L140H mutant from Listeria Monocytogenes | 分子名称: | ISOPROPYL ALCOHOL, Listeriolysin positive regulatory factor A, SODIUM ION | 著者 | Hall, M, Grundstrom, C, Hansen, S, Brannstrom, K, Johansson, J, Sauer-Eriksson, A.E. | 登録日 | 2019-03-05 | 公開日 | 2020-04-01 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.705 Å) | 主引用文献 | A Novel Growth-Based Selection Strategy Identifies New Constitutively Active Variants of the Major Virulence Regulator PrfA in Listeria monocytogenes. J.Bacteriol., 202, 2020
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5L2T
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![BU of 5l2t by Molmil](/molmil-images/mine/5l2t) | The X-ray co-crystal structure of human CDK6 and Ribociclib. | 分子名称: | 7-cyclopentyl-N,N-dimethyl-2-{[5-(piperazin-1-yl)pyridin-2-yl]amino}-7H-pyrrolo[2,3-d]pyrimidine-6-carboxamide, Cyclin-dependent kinase 6 | 著者 | Chen, P, Ferre, R.A, Deihl, W, Yu, X, He, Y.-A. | 登録日 | 2016-08-02 | 公開日 | 2016-08-24 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (2.37 Å) | 主引用文献 | Spectrum and Degree of CDK Drug Interactions Predicts Clinical Performance. Mol.Cancer Ther., 15, 2016
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6WC8
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7M9W
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![BU of 7m9w by Molmil](/molmil-images/mine/7m9w) | HIV-1 Protease (I84V) in Complex with NR02-73 | 分子名称: | (3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl [(2S,3R)-3-hydroxy-4-{[(1S)-1-hydroxy-2,3-dihydro-1H-indene-5-sulfonyl][(2S)-2-methylbutyl]amino}-1-phenylbutan-2-yl]carbamate, Protease, SULFATE ION | 著者 | Lockbaum, G.J, Schiffer, C.A. | 登録日 | 2021-03-31 | 公開日 | 2022-08-31 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.901 Å) | 主引用文献 | HIV-1 Protease (I84V) in Complex with NR02-73 To Be Published
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7M9S
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![BU of 7m9s by Molmil](/molmil-images/mine/7m9s) | HIV-1 Protease WT (NL4-3) in Complex with NR01-141 | 分子名称: | (3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl [(2S,3R)-3-hydroxy-4-{[(1S)-1-hydroxy-2,3-dihydro-1H-indene-5-sulfonyl](2-methylpropyl)amino}-1-phenylbutan-2-yl]carbamate, Protease, SULFATE ION | 著者 | Lockbaum, G.J, Schiffer, C.A. | 登録日 | 2021-03-31 | 公開日 | 2022-08-31 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.961 Å) | 主引用文献 | HIV-1 Protease WT (NL4-3) in Complex with NR01-141 To Be Published
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6QRB
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![BU of 6qrb by Molmil](/molmil-images/mine/6qrb) | Crystal structure of TrmD, a tRNA-(N1G37) methyltransferase, from Mycobacterium abscessus in complex with inhibitor | 分子名称: | 5-azanyl-3-[1-[[(3~{R})-1-(phenylmethyl)piperidin-3-yl]methyl]indol-6-yl]-1~{H}-pyrazole-4-carbonitrile, tRNA (guanine-N(1)-)-methyltransferase | 著者 | Thomas, S.E, Whitehouse, A.J, Coyne, A.G, Abell, C, Mendes, V, Blundell, T.L. | 登録日 | 2019-02-19 | 公開日 | 2020-03-18 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.66 Å) | 主引用文献 | Development of Inhibitors against Mycobacterium abscessus tRNA (m 1 G37) Methyltransferase (TrmD) Using Fragment-Based Approaches. J.Med.Chem., 62, 2019
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7M9X
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![BU of 7m9x by Molmil](/molmil-images/mine/7m9x) | HIV-1 Protease (I84V) in Complex with NR02-79 | 分子名称: | (3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl [(2S,3R)-4-{(2-ethylbutyl)[(1S)-1-hydroxy-2,3-dihydro-1H-indene-5-sulfonyl]amino}-3-hydroxy-1-phenylbutan-2-yl]carbamate, Protease, SULFATE ION | 著者 | Lockbaum, G.J, Schiffer, C.A. | 登録日 | 2021-03-31 | 公開日 | 2022-08-31 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.831 Å) | 主引用文献 | HIV-1 Protease (I84V) in Complex with NR02-79 To Be Published
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6TZO
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![BU of 6tzo by Molmil](/molmil-images/mine/6tzo) | Crystal Structure of Fungal RNA Kinase | 分子名称: | 2'-DEOXYGUANOSINE-5'-DIPHOSPHATE, PHOSPHATE ION, tRNA ligase | 著者 | Shuman, S, Goldgur, Y, Banerjee, A. | 登録日 | 2019-08-12 | 公開日 | 2019-11-06 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.69 Å) | 主引用文献 | Atomic structures of the RNA end-healing 5'-OH kinase and 2',3'-cyclic phosphodiesterase domains of fungal tRNA ligase: conformational switches in the kinase upon binding of the GTP phosphate donor. Nucleic Acids Res., 47, 2019
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6EGW
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![BU of 6egw by Molmil](/molmil-images/mine/6egw) | Crystal Structure of the Protein-Kinase A catalytic subunit from Criteculus Griseus in complex with compounds RKp017 and RKp117 | 分子名称: | [2-[(4-isoquinolin-5-ylsulfonyl-1,4-diazepan-1-yl)methyl]phenyl]boronic acid, alpha-D-ribofuranose, cAMP-dependent protein kinase catalytic subunit alpha, ... | 著者 | Mueller, J.M, Heine, A, Klebe, G. | 登録日 | 2017-09-12 | 公開日 | 2018-10-10 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (1.74 Å) | 主引用文献 | Conceptional Design of Self-Assembling Bisubstrate-like Inhibitors of Protein Kinase A Resulting in a Boronic Acid Glutamate Linkage Acs Omega, 2019
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7R4X
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![BU of 7r4x by Molmil](/molmil-images/mine/7r4x) | Cryo-EM reconstruction of the human 40S ribosomal subunit - Full map | 分子名称: | 18S ribosomal RNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... | 著者 | Pellegrino, S, Dent, K.C, Spikes, T, Warren, A.J. | 登録日 | 2022-02-09 | 公開日 | 2023-02-22 | 最終更新日 | 2024-04-24 | 実験手法 | ELECTRON MICROSCOPY (2.15 Å) | 主引用文献 | Cryo-EM reconstruction of the human 40S ribosomal subunit at 2.15 angstrom resolution. Nucleic Acids Res., 51, 2023
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7R2M
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![BU of 7r2m by Molmil](/molmil-images/mine/7r2m) | SYNJ2BP complex with a synthetic Vangl2 peptide (9mer). | 分子名称: | 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, CALCIUM ION, GLYCEROL, ... | 著者 | Carrasco, K, Cousido Siah, A, Gogl, G, Betzi, S, McEwen, A, Kostmann, C, Trave, G. | 登録日 | 2022-02-04 | 公開日 | 2023-05-17 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | SYNJ2BP PDZ domain in complex with a synthetic Vangl2 peptide. To Be Published
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6WFV
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![BU of 6wfv by Molmil](/molmil-images/mine/6wfv) | The crystal structure of a collagen galactosylhydroxylysyl glucosyltransferase from human | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, MAGNESIUM ION, MANGANESE (II) ION, ... | 著者 | Guo, H.-F, Tsai, C.-L, Miller, M.D, Phillips Jr, G.N, Tainer, J.A, Kurie, J.M. | 登録日 | 2020-04-04 | 公開日 | 2021-04-14 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | The crystal structure of a collagen galactosylhydroxylysyl glucosyltransferase from human To Be Published
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6QXT
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![BU of 6qxt by Molmil](/molmil-images/mine/6qxt) | Cas1-Cas2-Csn2-DNA dimer complex from the Type II-A CRISPR-Cas system | 分子名称: | CALCIUM ION, CRISPR-associated endonuclease Cas1, CRISPR-associated endoribonuclease Cas2, ... | 著者 | Wilkinson, M, Drabavicius, G, Silanskas, A, Gasiunas, G, Siksnys, V, Wigley, D.B. | 登録日 | 2019-03-08 | 公開日 | 2019-05-08 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (8.9 Å) | 主引用文献 | Structure of the DNA-Bound Spacer Capture Complex of a Type II CRISPR-Cas System. Mol.Cell, 75, 2019
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8GUV
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![BU of 8guv by Molmil](/molmil-images/mine/8guv) | LecA from Pseudomonas aeruginosa in complex with tolcapone (CAS: 134308-13-7) | 分子名称: | CALCIUM ION, PA-I galactophilic lectin, Tolcapone | 著者 | Kuhaudomlarp, S, Siebs, E, Varrot, A, Imberty, A, Titz, A. | 登録日 | 2022-09-13 | 公開日 | 2023-07-19 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.32 Å) | 主引用文献 | LecA from Pseudomonas aeruginosa in complex with tolcapone (CAS: 134308-13-7) To Be Published
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6QU6
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![BU of 6qu6 by Molmil](/molmil-images/mine/6qu6) | Adenovirus Serotype 26 (Ad26) in complex with sialic acid, pH4.0 | 分子名称: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, Fiber, ... | 著者 | Baker, A.T, Mundy, R.M, Parker, A.L, Rizkallah, P.J. | 登録日 | 2019-02-26 | 公開日 | 2019-09-18 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.03 Å) | 主引用文献 | Human adenovirus type 26 uses sialic acid-bearing glycans as a primary cell entry receptor. Sci Adv, 5, 2019
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5I6L
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![BU of 5i6l by Molmil](/molmil-images/mine/5i6l) | Crystal Structure of Copper Nitrite Reductase at 100K after 2.76 MGy | 分子名称: | ACETATE ION, COPPER (II) ION, Copper-containing nitrite reductase, ... | 著者 | Horrell, S, Hough, M.A, Strange, R.W. | 登録日 | 2016-02-16 | 公開日 | 2016-07-13 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.08 Å) | 主引用文献 | Serial crystallography captures enzyme catalysis in copper nitrite reductase at atomic resolution from one crystal. Iucrj, 3, 2016
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5I6K
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7RAT
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8SLB
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![BU of 8slb by Molmil](/molmil-images/mine/8slb) | X-ray structure of CorA N-terminal domain in complex with conformation-specific synthetic antibody C12 | 分子名称: | CHLORIDE ION, Cobalt/magnesium transport protein CorA, sAB C12 Heavy Chain, ... | 著者 | Dominik, P.K, Erramilli, S.K, Reddy, B.G, Kossiakoff, A.A. | 登録日 | 2023-04-21 | 公開日 | 2023-06-07 | 最終更新日 | 2023-07-26 | 実験手法 | X-RAY DIFFRACTION (2.04 Å) | 主引用文献 | Conformation-specific Synthetic Antibodies Discriminate Multiple Functional States of the Ion Channel CorA. J.Mol.Biol., 435, 2023
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5L16
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![BU of 5l16 by Molmil](/molmil-images/mine/5l16) | Crystal Structure of N-terminus truncated selenophosphate synthetase from Leishmania major | 分子名称: | Putative selenophosphate synthetase, SULFATE ION | 著者 | Faim, L.M, Silva, I.R, Pereira, H.M, Dias, M.B, Silva, M.T.A, Brandao-Neto, J, Thiemann, O.H. | 登録日 | 2016-07-28 | 公開日 | 2017-08-09 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.882 Å) | 主引用文献 | Trypanosomatid selenophosphate synthetase structure, function and interaction with selenocysteine lyase. Plos Negl Trop Dis, 14, 2020
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7P0J
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![BU of 7p0j by Molmil](/molmil-images/mine/7p0j) | Crystal structure of S.pombe Mdb1 BRCT domains | 分子名称: | CITRIC ACID, DNA damage response protein Mdb1, MAGNESIUM ION, ... | 著者 | Day, M, Oliver, A.W, Pearl, L.H. | 登録日 | 2021-06-29 | 公開日 | 2022-07-13 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.48 Å) | 主引用文献 | Phosphorylation-dependent assembly of DNA damage response systems and the central roles of TOPBP1. DNA Repair (Amst), 108, 2021
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8GBQ
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![BU of 8gbq by Molmil](/molmil-images/mine/8gbq) | Structure of RNF125 in complex with UbcH5b | 分子名称: | E3 ubiquitin-protein ligase RNF125, GLYCEROL, Ubiquitin-conjugating enzyme E2 D2, ... | 著者 | Middleton, A.J, Day, C.L, Fokkens, T.J. | 登録日 | 2023-02-27 | 公開日 | 2023-07-19 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.74 Å) | 主引用文献 | Zinc finger 1 of the RING E3 ligase, RNF125, interacts with the E2 to enhance ubiquitylation. Structure, 31, 2023
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7MXO
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![BU of 7mxo by Molmil](/molmil-images/mine/7mxo) | CryoEM structure of human NKCC1 | 分子名称: | CHLORIDE ION, POTASSIUM ION, Solute carrier family 12 member 2 | 著者 | Moseng, M.A. | 登録日 | 2021-05-19 | 公開日 | 2022-09-28 | 最終更新日 | 2023-05-31 | 実験手法 | ELECTRON MICROSCOPY (3.47 Å) | 主引用文献 | Inhibition mechanism of NKCC1 involves the carboxyl terminus and long-range conformational coupling. Sci Adv, 8, 2022
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6U5F
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![BU of 6u5f by Molmil](/molmil-images/mine/6u5f) | CryoEM Structure of Pyocin R2 - precontracted - collar | 分子名称: | Collar PA0615, Sheath PA0622, Tube PA0623 | 著者 | Ge, P, Avaylon, J, Scholl, D, Shneider, M.M, Browning, C, Buth, S.A, Plattner, M, Ding, K, Leiman, P.G, Miller, J.F, Zhou, Z.H. | 登録日 | 2019-08-27 | 公開日 | 2020-04-15 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Action of a minimal contractile bactericidal nanomachine. Nature, 580, 2020
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