7MUB
 
 | | KcsA Open gate E71V mutant in Potassium | | 分子名称: | Fab heavy chain, Fab light chain, POTASSIUM ION, ... | | 著者 | Rohaim, A, Li, J, Weingarth, M, Roux, B. | | 登録日 | 2021-05-14 | | 公開日 | 2022-03-23 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | A distinct mechanism of C-type inactivation in the Kv-like KcsA mutant E71V.
Nat Commun, 13, 2022
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6ZZH
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7OUO
 | | Crystal structure of RNA duplex [UCGUGCGA]2 in complex with Ba2+ cation | | 分子名称: | BARIUM ION, RNA (5'-R(*UP*CP*GP*UP*GP*CP*GP*A)-3') | | 著者 | Ruszkowski, M, Mao, S, Zheng, Y.Y, Ruszkowska, A, Sheng, J. | | 登録日 | 2021-06-12 | | 公開日 | 2022-03-30 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (2.212 Å) | | 主引用文献 | Structural Insights Into the 5'UG/3'GU Wobble Tandem in Complex With Ba 2+ Cation.
Front Mol Biosci, 8, 2021
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7MJT
 | | KcsA open gate E71V mutant with Barium | | 分子名称: | BARIUM ION, Fab heavy chain, Fab light chain, ... | | 著者 | Rohaim, A, Li, J, Weingarth, M, Roux, B. | | 登録日 | 2021-04-20 | | 公開日 | 2022-03-23 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | | 主引用文献 | A distinct mechanism of C-type inactivation in the Kv-like KcsA mutant E71V.
Nat Commun, 13, 2022
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7A27
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7MK6
 | | KcsA open gate E71V mutant with sodium | | 分子名称: | Fab heavy chain, Fab light chain, pH-gated potassium channel KcsA | | 著者 | Rohaim, A, Li, J, Weingarth, M, Roux, B. | | 登録日 | 2021-04-21 | | 公開日 | 2022-03-23 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | A distinct mechanism of C-type inactivation in the Kv-like KcsA mutant E71V.
Nat Commun, 13, 2022
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6ZZ5
 | | Structure of soluble SmhB of the tripartite alpha-pore forming toxin, Smh, from Serratia marcescens. | | 分子名称: | 1,2-ETHANEDIOL, SULFATE ION, SmhB | | 著者 | Churchill-Angus, A.M, Baker, P.J. | | 登録日 | 2020-08-03 | | 公開日 | 2021-03-31 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.84 Å) | | 主引用文献 | Characterisation of a tripartite alpha-pore forming toxin from Serratia marcescens
Sci Rep, 11, 2021
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7M7C
 | | Crystal Structure of Hip1 (Rv2224c) mutant - T466A/S228DHA (dehydroalanine) | | 分子名称: | Carboxylesterase A | | 著者 | Naffin-Olivos, J.L, Daab, A, Goldfarb, N.E, Doran, M.H, Baikovitz, J, Liu, D, Sun, S, White, A, Dunn, B.M, Rengarajan, J, Petsko, G.A, Ringe, D. | | 登録日 | 2021-03-27 | | 公開日 | 2022-03-30 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Inhibitors and Inactivators of Mycobacterium tuberculosis serine protease Hip1 (Rv2224c)
To Be Published
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6UB7
 | | Crystal structure of a GH128 (subgroup V) exo-beta-1,3-glucanase from Cryptococcus neoformans (CnGH128_V) | | 分子名称: | Glyco_hydro_cc domain-containing protein, POTASSIUM ION | | 著者 | Santos, C.R, Costa, P.A.C.R, Murakami, M.T. | | 登録日 | 2019-09-11 | | 公開日 | 2020-05-20 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structural insights into beta-1,3-glucan cleavage by a glycoside hydrolase family.
Nat.Chem.Biol., 16, 2020
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7A0G
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6OGS
 | | X-ray crystal structure of darunavir-resistant HIV-1 protease (P30) in complex with GRL-001 | | 分子名称: | (3S,3aR,5R,7aS,8S)-hexahydro-4H-3,5-methanofuro[2,3-b]pyran-8-yl [(2S,3R)-4-[{[2-(cyclopropylamino)-1,3-benzothiazol-6-yl]sulfonyl}(2-methylpropyl)amino]-1-(3-fluorophenyl)-3-hydroxybutan-2-yl]carbamate, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... | | 著者 | Bulut, H, Hattori, S.I, Aoki-Ogata, H, Hayashi, H, Aoki, M, Ghosh, A.K, Mitsuya, H. | | 登録日 | 2019-04-03 | | 公開日 | 2020-04-08 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.27 Å) | | 主引用文献 | Single atom changes in newly synthesized HIV protease inhibitors reveal structural basis for extreme affinity, high genetic barrier, and adaptation to the HIV protease plasticity.
Sci Rep, 10, 2020
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8E55
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7A26
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7ABO
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6OO0
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8B6E
 | | crystal structure of the DNA-binding short chromatophore-targeted protein sCTP-23166 from Paulinella chromatophora | | 分子名称: | 1,2-ETHANEDIOL, SODIUM ION, sCTP-23166 | | 著者 | Macorano, L, Applegate, V, Hoeppner, A, Smits, S.H.J, Nowack, E.C.M. | | 登録日 | 2022-09-27 | | 公開日 | 2023-07-12 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | | 主引用文献 | DNA-binding and protein structure of nuclear factors likely acting in genetic information processing in the Paulinella chromatophore.
Proc.Natl.Acad.Sci.USA, 120, 2023
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7A9X
 | | Structure of yeast Rmd9p in complex with 16nt target RNA | | 分子名称: | CHLORIDE ION, Protein RMD9, mitochondrial, ... | | 著者 | Hillen, H.S, Markov, D.A, Ireneusz, W.D, Hofmann, K.B, Cowan, A.T, Jones, J.L, Temiakov, D, Cramer, P, Anikin, M. | | 登録日 | 2020-09-02 | | 公開日 | 2021-04-07 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | | 主引用文献 | The pentatricopeptide repeat protein Rmd9 recognizes the dodecameric element in the 3'-UTRs of yeast mitochondrial mRNAs.
Proc.Natl.Acad.Sci.USA, 118, 2021
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6WQP
 | | GH5-4 broad specificity endoglucanase from Ruminococcus champanellensis | | 分子名称: | 1,2-ETHANEDIOL, BICARBONATE ION, Endoglucanase, ... | | 著者 | Bianchetti, C.M, Bingman, C.A, Smith, R.W, Glasgow, E.M, Fox, B.G. | | 登録日 | 2020-04-29 | | 公開日 | 2020-11-18 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | A structural and kinetic survey of GH5_4 endoglucanases reveals determinants of broad substrate specificity and opportunities for biomass hydrolysis.
J.Biol.Chem., 295, 2020
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7A5U
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7PC5
 | | The third PDZ domain of PDZD7 complexed with the PDZ-binding motif of EXOC4 | | 分子名称: | CALCIUM ION, Exocyst complex component 4, GLYCEROL, ... | | 著者 | Cousido-Siah, A, Trave, G, Gogl, G. | | 登録日 | 2021-08-03 | | 公開日 | 2022-04-20 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | A scalable strategy to solve structures of PDZ domains and their complexes.
Acta Crystallogr D Struct Biol, 78, 2022
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7A02
 | | Bacillus endospore appendages form a novel family of disulfide-linked pili | | 分子名称: | DUF3992 domain-containing protein | | 著者 | Pradhan, B, Liedtke, J, Sleutel, M, Lindback, T, Llarena, A.K, Brynildsrud, O, Aspholm, M, Remaut, H. | | 登録日 | 2020-08-06 | | 公開日 | 2021-04-28 | | 最終更新日 | 2021-09-15 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | Endospore Appendages: a novel pilus superfamily from the endospores of pathogenic Bacilli.
Embo J., 40, 2021
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6UJG
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5I96
 | | Crystal Structure of Human Mitochondrial Isocitrate Dehydrogenase (IDH2) R140Q Mutant Homodimer in Complex with AG-221 (Enasidenib) Inhibitor. | | 分子名称: | 2-methyl-1-[(4-[6-(trifluoromethyl)pyridin-2-yl]-6-{[2-(trifluoromethyl)pyridin-4-yl]amino}-1,3,5-triazin-2-yl)amino]propan-2-ol, ACETATE ION, CALCIUM ION, ... | | 著者 | Wei, W, Zhang, B, Jin, L, Jiang, F, DeLaBarre, B, Travins, J.A, Padyana, A.K. | | 登録日 | 2016-02-19 | | 公開日 | 2017-03-08 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | | 主引用文献 | AG-221, a First-in-Class Therapy Targeting Acute Myeloid Leukemia Harboring Oncogenic IDH2 Mutations.
Cancer Discov, 7, 2017
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6UJA
 | | Integrin alpha-v beta-8 in complex with pro-TGF-beta1 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | | 著者 | Campbell, M.G, Cormier, A, Cheng, Y, Nishimura, S.L. | | 登録日 | 2019-10-02 | | 公開日 | 2020-02-05 | | 最終更新日 | 2020-07-29 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Cryo-EM Reveals Integrin-Mediated TGF-beta Activation without Release from Latent TGF-beta.
Cell, 180, 2020
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7MHW
 | | Crystal structure of the protease inhibitor U-Omp19 from Brucella abortus fused to Maltose-binding protein | | 分子名称: | Maltose/maltodextrin-binding periplasmic protein,Outer membrane lipoprotein omp19, SULFATE ION | | 著者 | Darriba, M.L, Klinke, S, Otero, L.H, Cerutti, M.L, Cassataro, J, Pasquevich, K.A. | | 登録日 | 2021-04-15 | | 公開日 | 2022-04-20 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | | 主引用文献 | A disordered region retains the full protease inhibitor activity and the capacity to induce CD8 + T cells in vivo of the oral vaccine adjuvant U-Omp19.
Comput Struct Biotechnol J, 20, 2022
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