7MHW

Crystal structure of the protease inhibitor U-Omp19 from Brucella abortus fused to Maltose-binding protein

Summary for 7MHW

Entry DOI	10.2210/pdb7mhw/pdb
Descriptor	Maltose/maltodextrin-binding periplasmic protein,Outer membrane lipoprotein omp19, SULFATE ION (3 entities in total)
Functional Keywords	protease inhibitor, mbp-fusion protein, membrane protein
Biological source	Escherichia coli More
Total number of polymer chains	1
Total formula weight	52406.68
Authors	Darriba, M.L.,Klinke, S.,Otero, L.H.,Cerutti, M.L.,Cassataro, J.,Pasquevich, K.A. (deposition date: 2021-04-15, release date: 2022-04-20, Last modification date: 2023-10-18)
Primary citation	Laura Darriba, M.,Castro, C.P.,Coria, L.M.,Bruno, L.,Laura Cerutti, M.,Otero, L.H.,Chemes, L.B.,Rasia, R.M.,Klinke, S.,Cassataro, J.,Pasquevich, K.A. A disordered region retains the full protease inhibitor activity and the capacity to induce CD8 + T cells in vivo of the oral vaccine adjuvant U-Omp19. Comput Struct Biotechnol J, 20:5098-5114, 2022 Cited by PubMed: 36187929 DOI: 10.1016/j.csbj.2022.08.054 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.55 Å)

Structure validation