7N2M
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![BU of 7n2m by Molmil](/molmil-images/mine/7n2m) | Crystal structure of DNA polymerase alpha catalytic core in complex with dCTP and template/primer having T-C mismatch at the post-insertion site | 分子名称: | 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, DNA (5'-D(*AP*T*AP*GP*TP*CP*GP*CP*TP*CP*CP*AP*GP*GP*C)-3'), DNA polymerase alpha catalytic subunit, ... | 著者 | Tahirov, T.H, Baranovskiy, A.G, Babayeva, N.D. | 登録日 | 2021-05-29 | 公開日 | 2022-04-20 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Structural and functional insight into mismatch extension by human DNA polymerase alpha. Proc.Natl.Acad.Sci.USA, 119, 2022
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4UML
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![BU of 4uml by Molmil](/molmil-images/mine/4uml) | Crystal structure of ganglioside induced differentiation associated protein 2 (GDAP2) macro domain | 分子名称: | GANGLIOSIDE-INDUCED DIFFERENTIATION-ASSOCIATED PROTEIN 2 | 著者 | Elkins, J.M, Wang, J, Kopec, J, Wang, D, Strain-Damerell, C, Shrestha, L, Sieg, C, Tallant, C, Newman, J.A, von Delft, F, Bountra, C, Edwards, A, Knapp, S. | 登録日 | 2014-05-19 | 公開日 | 2014-05-28 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structure of Gdap2 To be Published
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7NQF
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8EQN
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6ML1
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![BU of 6ml1 by Molmil](/molmil-images/mine/6ml1) | Structure of the USP15 deubiquitinase domain in complex with an affinity-matured inhibitory Ubv | 分子名称: | 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, ... | 著者 | Singer, A.U, Teyra, J, Boehmelt, G, Lenter, M, Sicheri, F, Sidhu, S.S. | 登録日 | 2018-09-26 | 公開日 | 2019-01-23 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structural and Functional Characterization of Ubiquitin Variant Inhibitors of USP15. Structure, 27, 2019
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6PJX
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![BU of 6pjx by Molmil](/molmil-images/mine/6pjx) | Crystal Structure of G Protein-Coupled Receptor Kinase 5 (GRK5) in Complex with Calmodulin (CaM) | 分子名称: | CALCIUM ION, Calmodulin, G protein-coupled receptor kinase 5, ... | 著者 | Bhardwaj, A, Komolov, K.E, Sulon, S, Benovic, J.L. | 登録日 | 2019-06-28 | 公開日 | 2020-12-09 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.96 Å) | 主引用文献 | Structure of a GRK5-Calmodulin Complex Reveals Molecular Mechanism of GRK Activation and Substrate Targeting. Mol.Cell, 81, 2021
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8EYM
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![BU of 8eym by Molmil](/molmil-images/mine/8eym) | CRYSTAL STRUCTURE OF NAGB-II PHOSPHOSUGAR ISOMERASE FROM SHEWANELLA DENITRIFICANS OS217 IN COMPLEX WITH GLUCITOLAMINE-6-PHOSPHATE AND N-ACETYLGLUCOSAMINE-6-PHOSPHATE AT 2.31 A RESOLUTION | 分子名称: | 2-DEOXY-2-AMINO GLUCITOL-6-PHOSPHATE, 2-acetamido-2-deoxy-6-O-phosphono-alpha-D-glucopyranose, GLUCOSAMINE-6-PHOSPHATE DEAMINASE | 著者 | Rodriguez-Hernandez, A, Marcos-Viquez, J, Rodriguez-Romero, A, Bustos-Jaimes, I. | 登録日 | 2022-10-27 | 公開日 | 2023-05-17 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.311 Å) | 主引用文献 | Substrate binding in the allosteric site mimics homotropic cooperativity in the SIS-fold glucosamine-6-phosphate deaminases. Protein Sci., 32, 2023
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7PZT
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![BU of 7pzt by Molmil](/molmil-images/mine/7pzt) | Structure of the bacterial toxin, TecA, an asparagine deamidase from Alcaligenes faecalis. | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Urea amidohydrolase | 著者 | Dix, S.R, Aziz, A.A, Baker, P.J, Evans, C.A, Dickman, M.J, Farthing, R.J, King, Z.L.S, Nathan, S, Partridge, L.J, Raih, F.M, Sedelnikova, S.E, Thomas, M.S, Rice, D.W. | 登録日 | 2021-10-13 | 公開日 | 2022-11-02 | 最終更新日 | 2024-06-19 | 実験手法 | X-RAY DIFFRACTION (1.84 Å) | 主引用文献 | The structure of A. faecalis TecA provides insights into its role as an asparagine deamidase toxin which targets RhoA To Be Published
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6PO6
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![BU of 6po6 by Molmil](/molmil-images/mine/6po6) | MicroED Structure of a Natural Product VFAThiaGlu | 分子名称: | YFAThiaGlu | 著者 | Halaby, S, Gonen, T, Ting, C.P, Funk, M.A, van der Donk, W.A. | 登録日 | 2019-07-03 | 公開日 | 2019-08-07 | 最終更新日 | 2023-11-15 | 実験手法 | ELECTRON CRYSTALLOGRAPHY (1 Å) | 主引用文献 | Use of a scaffold peptide in the biosynthesis of amino acid-derived natural products. Science, 365, 2019
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8EOL
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6N03
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![BU of 6n03 by Molmil](/molmil-images/mine/6n03) | CO-bound Sperm Whale Myoglobin, room temperature structure, last 2 degrees of 5 degree total oscillation and 160 kGy dose | 分子名称: | CARBON MONOXIDE, Myoglobin, CO-bound, ... | 著者 | Finke, A.D, Wierman, J.L, Pare-Labrosse, O, Sarrachini, A, Besaw, J, Mehrabi, P, Gruner, S.M, Miller, R.J.D. | 登録日 | 2018-11-06 | 公開日 | 2019-03-27 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Fixed-target serial oscillation crystallography at room temperature. IUCrJ, 6, 2019
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6POP
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7N2W
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![BU of 7n2w by Molmil](/molmil-images/mine/7n2w) | The crystal structure of an FMN-dependent NADH-azoreductase, AzoA in complex with Red 40 | 分子名称: | 6-hydroxy-5-[(E)-(2-methoxy-5-methyl-4-sulfophenyl)diazenyl]naphthalene-2-sulfonic acid, FLAVIN MONONUCLEOTIDE, FMN dependent NADH:quinone oxidoreductase | 著者 | Arcinas, A.J, Fedorov, E, Kelly, L, Almo, S.C, Ghosh, A. | 登録日 | 2021-05-30 | 公開日 | 2022-06-01 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | 主引用文献 | Uncovering a novel mechanism of enzyme activation in multimeric azoreductases To Be Published
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7AT5
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![BU of 7at5 by Molmil](/molmil-images/mine/7at5) | Structure of protein kinase ck2 catalytic subunit (csnk2a1 gene product) in complex with the bivalent inhibitor KN2 | 分子名称: | 1,2-ETHANEDIOL, 2-(3,4-dichlorophenyl)ethanamine, Casein kinase II subunit alpha, ... | 著者 | Lindenblatt, D, Applegate, V, Nickelsen, A, Klussmann, M, Neundorf, I, Goetz, C, Jose, J, Niefind, K. | 登録日 | 2020-10-29 | 公開日 | 2021-08-04 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.77 Å) | 主引用文献 | Molecular Plasticity of Crystalline CK2 alpha ' Leads to KN2, a Bivalent Inhibitor of Protein Kinase CK2 with Extraordinary Selectivity. J.Med.Chem., 65, 2022
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7APO
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![BU of 7apo by Molmil](/molmil-images/mine/7apo) | Crystal structure of RARalpha ligand binding domain in complex with a fragment of the TIF2 coactivator | 分子名称: | 4-{[(5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)carbonyl]amino}benzoic acid, GLYCEROL, Nuclear receptor coactivator 2, ... | 著者 | le Maire, A, Guee, L, Bourguet, W. | 登録日 | 2020-10-19 | 公開日 | 2021-08-04 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structural Insights into the Interaction of the Intrinsically Disordered Co-activator TIF2 with Retinoic Acid Receptor Heterodimer (RXR/RAR). J.Mol.Biol., 433, 2021
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5MEO
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![BU of 5meo by Molmil](/molmil-images/mine/5meo) | Human Leukocyte Antigen presenting ILGKFLHRL | 分子名称: | 1,2-ETHANEDIOL, Beta-2-microglobulin, GLYCEROL, ... | 著者 | Rizkallah, P.J, Lloyd, A, Crowther, M, Cole, D.K, Sewell, A.K. | 登録日 | 2016-11-16 | 公開日 | 2016-12-07 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.772 Å) | 主引用文献 | Structural Mechanism Underpinning Cross-reactivity of a CD8+ T-cell Clone That Recognizes a Peptide Derived from Human Telomerase Reverse Transcriptase. J. Biol. Chem., 292, 2017
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7AK9
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![BU of 7ak9 by Molmil](/molmil-images/mine/7ak9) | Structure of Salmonella TacT3 toxin bound to TacA3 antitoxin C-terminal peptide | 分子名称: | ABC transporter, Acetyltransferase, DEPHOSPHO COENZYME A | 著者 | Grabe, G.J, Morgan, R.M.L, Hare, S.A, Helaine, S. | 登録日 | 2020-09-30 | 公開日 | 2021-08-18 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | 主引用文献 | Auxiliary interfaces support the evolution of specific toxin-antitoxin pairing. Nat.Chem.Biol., 17, 2021
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7AK7
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![BU of 7ak7 by Molmil](/molmil-images/mine/7ak7) | Structure of Salmonella TacT2 toxin bound to TacA2 antitoxin | 分子名称: | ACETYL COENZYME *A, Acetyltransferase, CHLORIDE ION, ... | 著者 | Grabe, G.J, Morgan, R.M.L, Hare, S.A, Helaine, S. | 登録日 | 2020-09-30 | 公開日 | 2021-08-18 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.14 Å) | 主引用文献 | Auxiliary interfaces support the evolution of specific toxin-antitoxin pairing. Nat.Chem.Biol., 17, 2021
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7AK8
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![BU of 7ak8 by Molmil](/molmil-images/mine/7ak8) | Structure of Salmonella TacT1 toxin bound to TacA1 antitoxin C-terminal peptide | 分子名称: | ACETYL COENZYME *A, GCN5 family acetyltransferase, GLYCEROL, ... | 著者 | Grabe, G.J, Morgan, R.M.L, Helaine, S, Hare, S.A. | 登録日 | 2020-09-30 | 公開日 | 2021-08-18 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Auxiliary interfaces support the evolution of specific toxin-antitoxin pairing. Nat.Chem.Biol., 17, 2021
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6N91
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![BU of 6n91 by Molmil](/molmil-images/mine/6n91) | Crystal Structure of Adenosine Deaminase from Vibrio cholerae Complexed with Pentostatin (Deoxycoformycin) | 分子名称: | 1,2-ETHANEDIOL, 2'-DEOXYCOFORMYCIN, 3-CYCLOHEXYL-1-PROPYLSULFONIC ACID, ... | 著者 | Maltseva, N, Kim, Y, Endres, M, Welk, L, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2018-11-30 | 公開日 | 2018-12-19 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | Crystal Structure of Adenosine Deaminase from Vibrio cholerae Complexed with Pentostatin (Deoxycoformycin) (CASP target) To Be Published
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6P1Z
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7ATP
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7Q54
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![BU of 7q54 by Molmil](/molmil-images/mine/7q54) | Single Particle Cryo-EM structure of photosynthetic A4B4-glyceraldehyde 3-phosphate dehydrogenase from Spinacia oleracia. | 分子名称: | Glyceraldehyde-3-phosphate dehydrogenase A, chloroplastic, Glyceraldehyde-3-phosphate dehydrogenase B, ... | 著者 | Marotta, R, Fermani, S, Sparla, F, Trost, P, Del Giudice, A. | 登録日 | 2021-11-02 | 公開日 | 2022-11-16 | 実験手法 | ELECTRON MICROSCOPY (8.9 Å) | 主引用文献 | Unravelling the regulation pathway of photosynthetic AB-GAPDH. Acta Crystallogr D Struct Biol, 78, 2022
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7AYV
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![BU of 7ayv by Molmil](/molmil-images/mine/7ayv) | X-ray crystallographic structure of (6-4)photolyase from Drosophila melanogaster at cryogenic temperature | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, RE11660p, ... | 著者 | Cellini, A, Wahlgren, W.Y, Henry, L, Westenhoff, S. | 登録日 | 2020-11-13 | 公開日 | 2021-08-18 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.79 Å) | 主引用文献 | The three-dimensional structure of Drosophila melanogaster (6-4) photolyase at room temperature. Acta Crystallogr D Struct Biol, 77, 2021
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6MGE
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![BU of 6mge by Molmil](/molmil-images/mine/6mge) | Structure of human 4-1BBL | 分子名称: | GLYCEROL, PHOSPHATE ION, Tumor necrosis factor ligand superfamily member 9 | 著者 | Kimberlin, C.R, Chin, S.M, Roe-Zurz, Z, Xu, A, Yang, Y. | 登録日 | 2018-09-13 | 公開日 | 2018-11-21 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | 主引用文献 | Structure of the 4-1BB/4-1BBL complex and distinct binding and functional properties of utomilumab and urelumab. Nat Commun, 9, 2018
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