3EHH
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4QSX
| Structure of the bromodomain of human ATPase family AAA domain-containing protein 2 (ATAD2) in complex with 3'-deoxy thymidine | 分子名称: | 1,2-ETHANEDIOL, 1-[(2R,5S)-5-(hydroxymethyl)tetrahydrofuran-2-yl]-5-methylpyrimidine-2,4(1H,3H)-dione, ATPase family AAA domain-containing protein 2, ... | 著者 | Chaikuad, A, Felletar, I, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Knapp, S, Structural Genomics Consortium (SGC) | 登録日 | 2014-07-06 | 公開日 | 2014-07-23 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.93 Å) | 主引用文献 | Structure-based approaches towards identification of fragments for the low-druggability ATAD2 bromodomain MedChemComm, 5, 2014
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2HNT
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4QU9
| Caspase-3 F128A | 分子名称: | ACE-ASP-GLU-VAL-ASP-CHLOROMETHYLKETONE INHIBITOR, AZIDE ION, Caspase-3 | 著者 | Cade, C, Swartz, P.D, MacKenzie, S.H, Clark, A.C. | 登録日 | 2014-07-10 | 公開日 | 2014-11-05 | 最終更新日 | 2017-11-22 | 実験手法 | X-RAY DIFFRACTION (1.561 Å) | 主引用文献 | Modifying caspase-3 activity by altering allosteric networks. Biochemistry, 53, 2014
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6VZ4
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7TAP
| Cryo-EM structure of archazolid A bound to yeast VO V-ATPase | 分子名称: | Archazolid A, V-type proton ATPase subunit a, vacuolar isoform, ... | 著者 | Keon, K.A, Rubinstein, J.L, Benlekbir, S, Kirsch, S.H, Muller, R. | 登録日 | 2021-12-21 | 公開日 | 2022-02-23 | 最終更新日 | 2022-03-30 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | Cryo-EM of the Yeast V O Complex Reveals Distinct Binding Sites for Macrolide V-ATPase Inhibitors. Acs Chem.Biol., 17, 2022
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1TGM
| Crystal structure of a complex formed between group II phospholipase A2 and aspirin at 1.86 A resolution | 分子名称: | 2-(ACETYLOXY)BENZOIC ACID, CALCIUM ION, Phospholipase A2, ... | 著者 | Singh, N, Jabeen, T, Sharma, S, Bhushan, A, Singh, T.P. | 登録日 | 2004-05-28 | 公開日 | 2004-06-08 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.86 Å) | 主引用文献 | Crystal structure of a complex formed between group II phospholipase A2 and aspirin at 1.86 A resolution To be Published
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6VZP
| HBV wild type capsid | 分子名称: | Capsid protein | 著者 | Zhao, Z, Wang, J, Zlotnick, A. | 登録日 | 2020-02-28 | 公開日 | 2020-09-30 | 最終更新日 | 2020-12-30 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | The Integrity of the Intradimer Interface of the Hepatitis B Virus Capsid Protein Dimer Regulates Capsid Self-Assembly. Acs Chem.Biol., 15, 2020
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2W2F
| CRYSTAL STRUCTURE OF SINGLE POINT MUTANT ARG48GLN OF P-COUMARIC ACID DECARBOXYLASE FROM LACTOBACILLUS PLANTARUM STRUCTURAL INSIGHTS INTO THE ACTIVE SITE AND DECARBOXYLATION CATALYTIC MECHANISM | 分子名称: | BARIUM ION, P-COUMARIC ACID DECARBOXYLASE | 著者 | Rodriguez, H, Angulo, I, De Las Rivas, B, Campillo, N, Paez, J.A, Munoz, R, Mancheno, J.M. | 登録日 | 2008-10-29 | 公開日 | 2010-02-09 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.73 Å) | 主引用文献 | P-Coumaric Acid Decarboxylase from Lactobacillus Plantarum: Structural Insights Into the Active Site and Decarboxylation Catalytic Mechanism. Proteins, 78, 2010
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1TE2
| Putative Phosphatase Ynic from Escherichia coli K12 | 分子名称: | 2-PHOSPHOGLYCOLIC ACID, 2-deoxyglucose-6-P phosphatase, CALCIUM ION | 著者 | Kim, Y, Joachimiak, A, Evdokimova, E, Savchenko, A, Edwards, A, Midwest Center for Structural Genomics (MCSG) | 登録日 | 2004-05-24 | 公開日 | 2004-08-03 | 最終更新日 | 2024-07-10 | 実験手法 | X-RAY DIFFRACTION (1.76 Å) | 主引用文献 | Crystal Structure of Putative Phosphatase Ynic from Escherichia coli K12 To be Published
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4QUR
| Crystal Structure of stachydrine demethylase in complex with cyanide, oxygen, and N-methyl proline in a new orientation | 分子名称: | 1-methyl-L-proline, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, COBALT HEXAMMINE(III), ... | 著者 | Agarwal, R, Andi, B, Gizzi, A, Bonanno, J.B, Almo, S.C, Orville, A.M. | 登録日 | 2014-07-11 | 公開日 | 2015-07-15 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.759 Å) | 主引用文献 | Tracking photoelectron induced in-crystallo enzyme catalysis To be Published
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5K71
| apo Dbr1 | 分子名称: | RNA lariat debranching enzyme, putative, SULFATE ION | 著者 | Clark, N.E, Taylor, A.B, Hart, P.J. | 登録日 | 2016-05-25 | 公開日 | 2016-12-07 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.57 Å) | 主引用文献 | The RNA lariat debranching enzyme Dbr1: metal dependence and branched RNA co-crystal structures Proc.Natl.Acad.Sci.USA, 2016
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7AZR
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5KBQ
| Pak1 in complex with bis-anilino pyrimidine inhibitor | 分子名称: | Serine/threonine-protein kinase PAK 1, [4-methyl-3-[methyl-[2-[(3-methylsulfonyl-5-morpholin-4-yl-phenyl)amino]pyrimidin-4-yl]amino]phenyl]methanol | 著者 | Ferguson, A. | 登録日 | 2016-06-03 | 公開日 | 2016-09-28 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.58 Å) | 主引用文献 | Optimization of Highly Kinase Selective Bis-anilino Pyrimidine PAK1 Inhibitors. ACS Med Chem Lett, 7, 2016
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7AZQ
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4R5Z
| Crystal structure of Rv3772 encoded aminotransferase | 分子名称: | 4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, GLYCEROL, ... | 著者 | Nasir, N, Anant, A, Vyas, R, Biswal, B.K. | 登録日 | 2014-08-22 | 公開日 | 2015-08-26 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Crystal structures of Mycobacterium tuberculosis HspAT and ArAT reveal structural basis of their distinct substrate specificities Sci Rep, 6, 2016
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1JTS
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5KCH
| SETDB1 in complex with an early stage, low affinity fragment candidate modelled at reduced occupancy into weak electron density | 分子名称: | 4-methoxy-N-[(pyridin-2-yl)methyl]aniline, DIMETHYL SULFOXIDE, Histone-lysine N-methyltransferase SETDB1, ... | 著者 | Tempel, W, Harding, R.J, Mader, P, Dobrovetsky, E, Walker, J.R, Brown, P.J, Schapira, M, Collins, P, Pearce, N, Brandao-Neto, J, Douangamath, A, von Delft, F, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Santhakumar, V, Structural Genomics Consortium (SGC) | 登録日 | 2016-06-06 | 公開日 | 2016-07-27 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | SETDB1 in complex with an early stage, low affinity fragment candidate modelled at reduced occupancy To Be Published
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6IP3
| Structure of human telomeric DNA at 1.4 Angstroms resolution | 分子名称: | DNA (5'-D(*AP*GP*GP*GP*TP*TP*AP*GP*GP*GP*TP*TP*AP*GP*GP*GP*TP*TP*AP*GP*GP*G)-3'), POTASSIUM ION | 著者 | Saikrishnan, K, Nuthanakanti, A, Srivatsan, S.G, Ahmad, I. | 登録日 | 2018-11-01 | 公開日 | 2019-05-15 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Probing G-quadruplex topologies and recognition concurrently in real time and 3D using a dual-app nucleoside probe. Nucleic Acids Res., 47, 2019
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3ZJ7
| Crystal structure of strictosidine glucosidase in complex with inhibitor-1 | 分子名称: | (1R,2S,3S,4R,5R)-4-(cyclohexylamino)-5-(hydroxymethyl)cyclopentane-1,2,3-triol, STRICTOSIDINE-O-BETA-D-GLUCOSIDASE | 著者 | Xia, L, Lin, H, Panjikar, S, Ruppert, M, Castiglia, A, Rajendran, C, Wang, M, Schuebel, H, Warzecha, H, Jaeger, V, Stoeckigt, J. | 登録日 | 2013-01-17 | 公開日 | 2014-02-05 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Ligand Structures of Synthetic Deoxa-Pyranosylamines with Raucaffricine and Strictosidine Glucosidases Provide Structural Insights Into Their Binding and Inhibitory Behaviours. J.Enzyme.Inhib.Med.Chem., 30, 2015
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1K02
| Crystal Structure of Old Yellow Enzyme Mutant Gln114Asn | 分子名称: | FLAVIN MONONUCLEOTIDE, MAGNESIUM ION, NADPH DEHYDROGENASE 1 | 著者 | Brown, B.J, Hyun, J, Duvvuri, S.D, Karplus, P.A, Massey, V. | 登録日 | 2001-09-18 | 公開日 | 2001-09-26 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | The role of glutamine 114 in old yellow enzyme J.Biol.Chem., 277, 2002
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7SV9
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7T00
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7SVX
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3E3Y
| Q138F HincII bound to GTTAAC and cocrystallized with 5 mM Ca2+ | 分子名称: | 5'-D(*DGP*DCP*DCP*DGP*DGP*DTP*DTP*DAP*DAP*DCP*DCP*DGP*DGP*DC)-3', CALCIUM ION, SODIUM ION, ... | 著者 | Horton, N.C, Babic, A.C, Little, E.J, Manohar, V.M. | 登録日 | 2008-08-08 | 公開日 | 2008-08-26 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.13 Å) | 主引用文献 | DNA distortion and specificity in a sequence-specific endonuclease. J.Mol.Biol., 383, 2008
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