7TAP
Cryo-EM structure of archazolid A bound to yeast VO V-ATPase
Summary for 7TAP
Entry DOI | 10.2210/pdb7tap/pdb |
Related | 7TAO |
EMDB information | 25779 25780 |
Descriptor | V-type proton ATPase subunit c', V-type proton ATPase subunit c'', V0 assembly protein 1, ... (9 entities in total) |
Functional Keywords | inhibitor, complex, proton pump, atpase, membrane protein |
Biological source | Saccharomyces cerevisiae (baker's yeast) More |
Total number of polymer chains | 15 |
Total formula weight | 359328.99 |
Authors | Keon, K.A.,Rubinstein, J.L.,Benlekbir, S.,Kirsch, S.H.,Muller, R. (deposition date: 2021-12-21, release date: 2022-02-23, Last modification date: 2022-03-30) |
Primary citation | Keon, K.A.,Benlekbir, S.,Kirsch, S.H.,Muller, R.,Rubinstein, J.L. Cryo-EM of the Yeast V O Complex Reveals Distinct Binding Sites for Macrolide V-ATPase Inhibitors. Acs Chem.Biol., 17:619-628, 2022 Cited by PubMed: 35148071DOI: 10.1021/acschembio.1c00894 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (2.8 Å) |
Structure validation
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