3TX4
 
 | | Crystal Structure of Mutant (C354A) M. tuberculosis LD-transpeptidase type 2 | | 分子名称: | Mycobacterium Tuberculosis LD-transpeptidase type 2 | | 著者 | Erdemli, S, Bianchet, M.A, Gupta, R, Lamichhane, G, Amzel, L.M. | | 登録日 | 2011-09-22 | | 公開日 | 2012-12-05 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.32 Å) | | 主引用文献 | Targeting the Cell Wall of Mycobacterium tuberculosis: Structure and Mechanism of L,D-Transpeptidase 2.
Structure, 20, 2012
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6DFT
 | | Trypanosoma brucei deoxyhypusine synthase | | 分子名称: | Deoxyhypusine synthase, Deoxyhypusine synthase regulatory subunit, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... | | 著者 | Tomchick, D.R, Phillips, M.A, Afanador, G.A. | | 登録日 | 2018-05-15 | | 公開日 | 2018-08-08 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | | 主引用文献 | Trypanosomatid Deoxyhypusine Synthase Activity Is Dependent on Shared Active-Site Complementation between Pseudoenzyme Paralogs.
Structure, 26, 2018
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4ONF
 | | Fab fragment of 3D6 in complex with amyloid beta 1-7 | | 分子名称: | 3D6 FAB ANTIBODY HEAVY CHAIN, 3D6 FAB ANTIBODY LIGHT CHAIN, Amyloid beta A4 protein | | 著者 | Feinberg, H, Saldanha, J.W, Diep, L, Goel, A, Widom, A, Veldman, G.M, Weis, W.I, Schenk, D, Basi, G.S. | | 登録日 | 2014-01-28 | | 公開日 | 2014-06-11 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Crystal structure reveals conservation of amyloid-beta conformation recognized by 3D6 following humanization to bapineuzumab.
Alzheimers Res Ther, 6, 2014
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8GLU
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4OTI
 | | Crystal Structure of PRK1 Catalytic Domain in Complex with Tofacitinib | | 分子名称: | 3-{(3R,4R)-4-methyl-3-[methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]piperidin-1-yl}-3-oxopropanenitrile, Serine/threonine-protein kinase N1 | | 著者 | Chamberlain, P.P, Delker, S, Pagarigan, B, Mahmoudi, A, Jackson, P, Abbassian, M, Muir, J, Raheja, N, Cathers, B. | | 登録日 | 2014-02-13 | | 公開日 | 2014-08-27 | | 最終更新日 | 2018-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.93 Å) | | 主引用文献 | Crystal Structures of PRK1 in Complex with the Clinical Compounds Lestaurtinib and Tofacitinib Reveal Ligand Induced Conformational Changes.
Plos One, 9, 2014
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4F1W
 | | Crystal structure of 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase from Salmonella enterica with Adenine | | 分子名称: | 1,2-ETHANEDIOL, 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase, ADENINE, ... | | 著者 | Haapalainen, A.M, Thomas, K, Bonanno, J.B, Almo, S.C, Schramm, V.L. | | 登録日 | 2012-05-07 | | 公開日 | 2013-05-01 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.36 Å) | | 主引用文献 | Crystal structure of 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase from Salmonella enterica with Adenine
Structure, 21, 2013
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2Y2W
 | | Elucidation of the substrate specificity and protein structure of AbfB, a family 51 alpha-L-arabinofuranosidase from Bifidobacterium longum. | | 分子名称: | ARABINOFURANOSIDASE | | 著者 | Lagaert, S, Schoepe, J, Delcour, J.A, Lavigne, R, Strelkov, S.V, Courtin, C.M, Mikkelsen, N.E, Sandgren, M, Volckaert, G. | | 登録日 | 2010-12-16 | | 公開日 | 2011-12-28 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Elucidation of the Substrate Specificity and Protein Structure of Abfb, a Family 51 Alpha-L- Arabinofuranosidase from Bifidobacterium Longum.
To be Published
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1I1N
 | | HUMAN PROTEIN L-ISOASPARTATE O-METHYLTRANSFERASE WITH S-ADENOSYL HOMOCYSTEINE | | 分子名称: | PROTEIN-L-ISOASPARTATE O-METHYLTRANSFERASE, S-ADENOSYL-L-HOMOCYSTEINE | | 著者 | Smith, C.D, Chattopadhyay, D, Carson, M, Friedman, A.M, Skinner, M.M. | | 登録日 | 2001-02-02 | | 公開日 | 2002-03-13 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Crystal structure of human L-isoaspartyl-O-methyl-transferase with S-adenosyl homocysteine at 1.6-A resolution and modeling of an isoaspartyl-containing peptide at the active site.
Protein Sci., 11, 2002
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1W6Q
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8SV8
 | | Cryo-EM structure of a double loaded human UBA7-UBE2L6-ISG15 thioester mimetic complex from a composite map | | 分子名称: | ADENOSINE MONOPHOSPHATE, Ubiquitin-like modifier-activating enzyme 7, Ubiquitin-like protein ISG15, ... | | 著者 | Afsar, M, Jia, L, Ruben, E.A, Olsen, S.K. | | 登録日 | 2023-05-15 | | 公開日 | 2023-10-11 | | 実験手法 | ELECTRON MICROSCOPY (3.38 Å) | | 主引用文献 | Cryo-EM structures of Uba7 reveal the molecular basis for ISG15 activation and E1-E2 thioester transfer.
Nat Commun, 14, 2023
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6DND
 | | Crystal structure of wild-type (WT) human Glutamate oxaloacetate transaminase 1 (GOT1) | | 分子名称: | Aspartate aminotransferase, cytoplasmic, PYRIDOXAL-5'-PHOSPHATE, ... | | 著者 | Assar, Z, Holt, M.C, Stein, A.J, Lairson, L, Lyssiotis, C.A. | | 登録日 | 2018-06-06 | | 公開日 | 2018-11-14 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Biochemical Characterization and Structure-Based Mutational Analysis Provide Insight into the Binding and Mechanism of Action of Novel Aspartate Aminotransferase Inhibitors.
Biochemistry, 57, 2018
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2XHW
 | | HCV-J4 NS5B Polymerase Trigonal Crystal Form | | 分子名称: | RNA-directed RNA polymerase | | 著者 | Harrus, D, Ahmed-El-Sayed, N, Simister, P.C, Miller, S, Triconnet, M, Hagedorn, C.H, Mahias, K, Rey, F.A, Astier-Gin, T, Bressanelli, S. | | 登録日 | 2010-06-21 | | 公開日 | 2010-08-04 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (2.66 Å) | | 主引用文献 | Further Insights Into the Roles of GTP and the C- Terminus of the Hepatitis C Virus Polymerase in the Initiation of RNA Synthesis
J.Biol.Chem., 285, 2010
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3KYW
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5DMU
 | | Structure of the NHEJ polymerase from Methanocella paludicola | | 分子名称: | 1,2-ETHANEDIOL, GLYCEROL, NHEJ Polymerase, ... | | 著者 | Brissett, N.C, Bartlett, E.J, Doherty, A.J. | | 登録日 | 2015-09-09 | | 公開日 | 2015-10-07 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.949 Å) | | 主引用文献 | Molecular basis for DNA strand displacement by NHEJ repair polymerases.
Nucleic Acids Res., 44, 2016
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3UD2
 | | Crystal structure of Selenomethionine ZU5A-ZU5B protein domains of human erythrocyte ankyrin | | 分子名称: | Ankyrin-1, CHLORIDE ION, ETHANOL, ... | | 著者 | Yasunaga, M, Ipsaro, J.J, Mondragon, A. | | 登録日 | 2011-10-27 | | 公開日 | 2012-02-22 | | 最終更新日 | 2019-12-25 | | 実験手法 | X-RAY DIFFRACTION (2.21 Å) | | 主引用文献 | Structurally Similar but Functionally Diverse ZU5 Domains in Human Erythrocyte Ankyrin.
J.Mol.Biol., 417, 2012
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2G6F
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8H2I
 | | Near-atomic structure of five-fold averaged PBCV-1 capsid | | 分子名称: | MCPv1, MCPv2, MCPv3, ... | | 著者 | Shao, Q, Agarkova, I.V, Noel, E.A, Dunigan, D.D, Liu, Y, Wang, A, Guo, M, Xie, L, Zhao, X, Rossmann, M.G, Van Etten, J.L, Klose, T, Fang, Q. | | 登録日 | 2022-10-06 | | 公開日 | 2022-11-16 | | 最終更新日 | 2023-09-06 | | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | | 主引用文献 | Near-atomic, non-icosahedrally averaged structure of giant virus Paramecium bursaria chlorella virus 1.
Nat Commun, 13, 2022
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6RAU
 | | PostS3_Pmar_lig4_WT | | 分子名称: | ADENOSINE MONOPHOSPHATE, ATP-dependent DNA ligase, DNA (5'-D(*AP*TP*TP*GP*CP*GP*AP*CP*CP*CP*CP*AP*CP*TP*AP*TP*CP*GP*GP*AP*A)-3'), ... | | 著者 | Leiros, H.K.S, Williamson, A. | | 登録日 | 2019-04-08 | | 公開日 | 2019-07-10 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (1.99 Å) | | 主引用文献 | Structural intermediates of a DNA-ligase complex illuminate the role of the catalytic metal ion and mechanism of phosphodiester bond formation.
Nucleic Acids Res., 47, 2019
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4W7J
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5VY4
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4F07
 | | Structure of the Styrene Monooxygenase Flavin Reductase (SMOB) from Pseudomonas putida S12 | | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, NITRATE ION, SULFATE ION, ... | | 著者 | Sazinsky, M.H, Morrison, E, Kantz, A, Gassner, G. | | 登録日 | 2012-05-03 | | 公開日 | 2013-05-08 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structure and Mechanism of Styrene Monooxygenase Reductase: New Insight into the FAD-Transfer Reaction.
Biochemistry, 52, 2013
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5DWP
 | | Crystal Structure of human transthyretin (TTR) processed with the CrystalDirect automated mounting and cryo-cooling technology | | 分子名称: | Transthyretin | | 著者 | Zander, U, Cornaciu, I, Forsyth, T, Yee, A, Marquez, J.A. | | 登録日 | 2015-09-22 | | 公開日 | 2016-04-13 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | | 主引用文献 | Automated harvesting and processing of protein crystals through laser photoablation.
Acta Crystallogr D Struct Biol, 72, 2016
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4OVD
 | | Crystal structure of a putative peptidoglycan glycosyltransferase from Atopobium parvulum DSM 20469 | | 分子名称: | CALCIUM ION, Peptidoglycan glycosyltransferase | | 著者 | Filippova, E.V, Wawrzak, Z, Kiryukhina, O, Babnigg, G, Clancy, S, Joachimiak, A, Anderson, W.F, Midwest Center for Structural Genomics (MCSG) | | 登録日 | 2014-02-21 | | 公開日 | 2014-03-12 | | 最終更新日 | 2018-01-24 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Crystal structure of a putative peptidoglycan glycosyltransferase from Atopobium parvulum DSM 20469
To be Published
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2GAE
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5KN4
 | | Pavine N-methyltransferase apoenzyme pH 6.0 | | 分子名称: | Pavine N-methyltransferase | | 著者 | Torres, M.A, Hoffarth, E, Eugenio, L, Savtchouk, J, Chen, X, Morris, J, Facchini, P.J, Ng, K.K.S. | | 登録日 | 2016-06-27 | | 公開日 | 2016-09-07 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (1.99 Å) | | 主引用文献 | Structural and Functional Studies of Pavine N-Methyltransferase from Thalictrum flavum Reveal Novel Insights into Substrate Recognition and Catalytic Mechanism.
J.Biol.Chem., 291, 2016
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