2X4P
 
 | | Crystal structure of MHC CLass I HLA-A2.1 bound to a photocleavable peptide | | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, BETA-2-MICROGLOBULIN, GLYCEROL, ... | | 著者 | Celie, P.H.N, Toebes, M, Rodenko, B, Ovaa, H, Perrakis, A, Schumacher, T.N.M. | | 登録日 | 2010-02-02 | | 公開日 | 2010-03-02 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Class I Major Histocompatibility Complexes Loaded by a Periodate Trigger.
J.Am.Chem.Soc., 131, 2009
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5IWT
 | | Structure of Transient Receptor Potential (TRP) channel TRPV6 in the presence of gadolinium | | 分子名称: | 6-(5-METHYL-2-OXO-IMIDAZOLIDIN-4-YL)-HEXANOIC ACID, GADOLINIUM ATOM, Transient receptor potential cation channel subfamily V member 6 | | 著者 | Saotome, K, Singh, A.K, Yelshanskaya, M.V, Sobolevsky, A.I. | | 登録日 | 2016-03-22 | | 公開日 | 2016-06-15 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (3.8 Å) | | 主引用文献 | Crystal structure of the epithelial calcium channel TRPV6.
Nature, 534, 2016
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5G0Y
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5WPB
 | | Crystal structure of fragment 3-(3-(pyridin-2-ylmethoxy)quinoxalin-2-yl)propanoic acid bound in the ubiquitin binding pocket of the HDAC6 zinc-finger domain | | 分子名称: | 3-{3-[(pyridin-2-yl)methoxy]quinoxalin-2-yl}propanoic acid, Histone deacetylase 6, UNKNOWN ATOM OR ION, ... | | 著者 | Harding, R.J, Tempel, W, Ferreira de Freitas, R, Franzoni, I, Ravichandran, M, Lautens, M, Santhakumar, V, Schapira, M, Bountra, C, Edwards, A.M, Arrowsmith, C.H, Structural Genomics Consortium (SGC) | | 登録日 | 2017-08-04 | | 公開日 | 2017-08-23 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | | 主引用文献 | Small Molecule Antagonists of the Interaction between the Histone Deacetylase 6 Zinc-Finger Domain and Ubiquitin.
J. Med. Chem., 60, 2017
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5FSS
 | | Structure of thermolysin prepared by the 'soak-and-freeze' method under 40 bar of krypton pressure | | 分子名称: | CALCIUM ION, GLYCEROL, KRYPTON, ... | | 著者 | Lafumat, B, Mueller-Dieckmann, C, Colloc'h, N, Prange, T, Royant, A, van der Linden, P, Carpentier, P. | | 登録日 | 2016-01-07 | | 公開日 | 2016-10-26 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Gas-Sensitive Biological Crystals Processed in Pressurized Oxygen and Krypton Atmospheres: Deciphering Gas Channels in Proteins Using a Novel `Soak-and-Freeze' Methodology.
J.Appl.Crystallogr., 49, 2016
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2WHB
 | | Truncation and Optimisation of Peptide Inhibitors of CDK2, Cyclin A Through Structure Guided Design | | 分子名称: | ARG-ARG-L3O-PFF, CELL DIVISION PROTEIN KINASE 2, CYCLIN-A2 | | 著者 | Kontopidis, G, Andrews, M.J, McInnes, C, Plater, A, Innes, L, Renachowski, S, Cowan, A, Fischer, P.M. | | 登録日 | 2009-05-03 | | 公開日 | 2009-06-09 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Truncation and optimisation of peptide inhibitors of cyclin-dependent kinase 2-cyclin a through structure-guided design.
Chemmedchem, 4, 2009
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8PMP
 | | Structure of the human nuclear cap-binding complex bound to ARS2[147-871] and m7GTP | | 分子名称: | 7N-METHYL-8-HYDROGUANOSINE-5'-TRIPHOSPHATE, Nuclear cap-binding protein subunit 1, Nuclear cap-binding protein subunit 2, ... | | 著者 | Dubiez, E, Pellegrini, E, Foucher, A.E, Cusack, S, Kadlec, J. | | 登録日 | 2023-06-29 | | 公開日 | 2024-01-17 | | 実験手法 | ELECTRON MICROSCOPY (3.43 Å) | | 主引用文献 | Structural basis for competitive binding of productive and degradative co-transcriptional effectors to the nuclear cap-binding complex.
Cell Rep, 43, 2024
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5J9M
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5JN2
 | | Crystal structure of TgCDPK1 bound to NVPACU106 | | 分子名称: | 1,2-ETHANEDIOL, CALCIUM ION, Calmodulin-domain protein kinase 1, ... | | 著者 | El Bakkouri, M, Walker, J.R, Loppnau, P, Graslund, S, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Hui, R, Lovato, D.V, Structural Genomics Consortium (SGC) | | 登録日 | 2016-04-29 | | 公開日 | 2016-05-25 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Crystal structure of TgCDPK1 bound to NVPACU106
To Be Published
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7ZKG
 | | C-Methyltransferase PsmD from Streptomyces griseofuscus with bound cofactor (crystal form 2) | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, Methyltransferase, PHOSPHATE ION, ... | | 著者 | Weiergraeber, O.H, Amariei, D.A, Pozhydaieva, N, Pietruszka, J. | | 登録日 | 2022-04-13 | | 公開日 | 2022-12-28 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Enzymatic C3-Methylation of Indoles Using Methyltransferase PsmD-Crystal Structure, Catalytic Mechanism, and Preparative Applications
Acs Catalysis, 2022
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6R5Z
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6HRS
 | | Structure of the TRPML2 ELD at pH 4.5 | | 分子名称: | GLYCEROL, Mucolipin-2 | | 著者 | Bader, N, Viet, K.K, Wagner, A, Hellmich, U.A, Schindelin, H. | | 登録日 | 2018-09-28 | | 公開日 | 2019-06-19 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | | 主引用文献 | Structure of the Human TRPML2 Ion Channel Extracytosolic/Lumenal Domain.
Structure, 27, 2019
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4QL3
 | | Crystal Structure of a GDP-bound G12R Oncogenic Mutant of Human GTPase KRas | | 分子名称: | GTPase KRas, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION | | 著者 | Hunter, J.C, Manandhar, A, Gurbani, D, Chen, Z, Westover, K.D. | | 登録日 | 2014-06-10 | | 公開日 | 2015-06-10 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.041 Å) | | 主引用文献 | Biochemical and Structural Analysis of Common Cancer-Associated KRAS Mutations.
Mol Cancer Res., 13, 2015
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5FD5
 | | manganese uptake regulator | | 分子名称: | 1,2-ETHANEDIOL, Ferric uptake regulation protein, SULFATE ION | | 著者 | Bellini, D, Lebedev, A, Keegan, R, Walsh, M.A. | | 登録日 | 2015-12-15 | | 公開日 | 2016-12-28 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.91 Å) | | 主引用文献 | Structure of an apo metal-free manganese uptake regulator, mur
To Be Published
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3KKW
 | | Crystal structure of His-tagged form of PA4794 protein | | 分子名称: | 1,2-ETHANEDIOL, Putative uncharacterized protein, SULFATE ION | | 著者 | Majorek, K.A, Chruszcz, M, Joachimiak, A, Minor, W, Midwest Center for Structural Genomics (MCSG) | | 登録日 | 2009-11-06 | | 公開日 | 2009-11-24 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.41 Å) | | 主引用文献 | Double trouble-Buffer selection and His-tag presence may be responsible for nonreproducibility of biomedical experiments.
Protein Sci., 23, 2014
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4QLO
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4XIW
 | | Carbonic anhydrase Cah3 from Chlamydomonas reinhardtii in complex with acetazolamide | | 分子名称: | 5-ACETAMIDO-1,3,4-THIADIAZOLE-2-SULFONAMIDE, Carbonic anhydrase, alpha type, ... | | 著者 | Hainzl, T, Grundstrom, C, Benlloch, R, Shevela, D, Shutova, T, Messinger, J, Samuelsson, G, Sauer-Eriksson, A.E. | | 登録日 | 2015-01-07 | | 公開日 | 2015-02-11 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Crystal Structure and Functional Characterization of Photosystem II-Associated Carbonic Anhydrase CAH3 in Chlamydomonas reinhardtii.
Plant Physiol., 167, 2015
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7TYE
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7LSV
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6DVH
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6R7H
 | | Structural basis of Cullin-2 RING E3 ligase regulation by the COP9 signalosome | | 分子名称: | COP9 signalosome complex subunit 1, COP9 signalosome complex subunit 2, COP9 signalosome complex subunit 3, ... | | 著者 | Faull, S.V, Lau, A.M.C, Beuron, F, Cronin, N.B, Morris, E.P, Politis, A. | | 登録日 | 2019-03-28 | | 公開日 | 2019-08-28 | | 最終更新日 | 2024-05-22 | | 実験手法 | ELECTRON MICROSCOPY (8.8 Å) | | 主引用文献 | Structural basis of Cullin 2 RING E3 ligase regulation by the COP9 signalosome.
Nat Commun, 10, 2019
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5BJY
 | | x-ray structure of the PglF 4,5-dehydratase from campylobacter jejuni, variant M405Y, in complex with UDP | | 分子名称: | 1,2-ETHANEDIOL, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, SODIUM ION, ... | | 著者 | Riegert, A.S, Thoden, J.B, Holden, H.M. | | 登録日 | 2017-09-12 | | 公開日 | 2017-11-08 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Structural and Biochemical Investigation of PglF from Campylobacter jejuni Reveals a New Mechanism for a Member of the Short Chain Dehydrogenase/Reductase Superfamily.
Biochemistry, 56, 2017
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6RAR
 | | Pmar-Lig_PreS3-Mn | | 分子名称: | ADENOSINE MONOPHOSPHATE, ATP-dependent DNA ligase, DNA (5'-D(*TP*TP*CP*CP*GP*AP*CP*AP*GP*TP*GP*GP*GP*GP*TP*CP*GP*CP*AP*AP*T)-3'), ... | | 著者 | Leiros, H.K.S, Williamson, A. | | 登録日 | 2019-04-07 | | 公開日 | 2019-07-10 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.785 Å) | | 主引用文献 | Structural intermediates of a DNA-ligase complex illuminate the role of the catalytic metal ion and mechanism of phosphodiester bond formation.
Nucleic Acids Res., 47, 2019
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8Q5H
 | | Human KMN network (outer kinetochore) | | 分子名称: | Kinetochore protein Spc24, Kinetochore protein Spc25, Kinetochore scaffold 1, ... | | 著者 | Raisch, T, Polley, S, Vetter, I, Musacchio, A, Raunser, S. | | 登録日 | 2023-08-09 | | 公開日 | 2024-02-14 | | 最終更新日 | 2024-09-04 | | 実験手法 | ELECTRON MICROSCOPY (4.5 Å) | | 主引用文献 | Structure of the human KMN complex and implications for regulation of its assembly.
Nat.Struct.Mol.Biol., 31, 2024
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7H0N
 | | Crystal structure of SARS-CoV-2 NSP3 Macrodomain in complex with ASAP-0011215-001 | | 分子名称: | 7-[(1R)-1-({(6M)-6-[(4R)-imidazo[1,5-a]pyridin-6-yl]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}amino)-2-methylpropyl]-3,4-dihydro-1lambda~6~-benzothiopyran-1,1(2H)-dione, Papain-like protease nsp3 | | 著者 | Aschenbrenner, J.C, Fearon, D, Tomlinson, C.W.E, Marples, P.G, Fairhead, M, Balcomb, B.H, Chandran, A.V, Godoy, A.S, Koekemoer, L, Lithgo, R.M, Ni, X, Thompson, W, Wang, S, Wild, C, Williams, E.P, Winokan, M, Walsh, M.A, von Delft, F. | | 登録日 | 2024-01-23 | | 公開日 | 2024-05-15 | | 実験手法 | X-RAY DIFFRACTION (1.41 Å) | | 主引用文献 | Group deposition of SARS-CoV-2 NSP3 Macrodomain in complex with inhibitors from the ASAP AViDD centre
To Be Published
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