7FS4
| Structure of liver pyruvate kinase in complex with allosteric modulator 16 | 分子名称: | 1,6-di-O-phosphono-beta-D-fructofuranose, 4,4',5-trihydroxy-N-{[4-(3-hydroxybenzene-1-sulfonyl)phenyl]methyl}[1,1'-biphenyl]-2-sulfonamide, MAGNESIUM ION, ... | 著者 | Lulla, A, Nilsson, O, Brear, P, Nain-Perez, A, Grotli, M, Hyvonen, M. | 登録日 | 2022-12-18 | 公開日 | 2023-04-12 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (2.19 Å) | 主引用文献 | Tuning liver pyruvate kinase activity up or down with a new class of allosteric modulators. Eur.J.Med.Chem., 250, 2023
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7FS9
| Structure of liver pyruvate kinase in complex with allosteric modulator 22 | 分子名称: | 1,6-di-O-phosphono-beta-D-fructofuranose, 4-[4-(4-aminobenzene-1-sulfonyl)piperazine-1-sulfonyl]benzene-1,2-diol, MAGNESIUM ION, ... | 著者 | Lulla, A, Nilsson, O, Brear, P, Nain-Perez, A, Grotli, M, Hyvonen, M. | 登録日 | 2022-12-18 | 公開日 | 2023-04-12 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (1.721 Å) | 主引用文献 | Tuning liver pyruvate kinase activity up or down with a new class of allosteric modulators. Eur.J.Med.Chem., 250, 2023
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8T84
| Racemic mixture of amyloid beta segment 35-MVGGVV-40 forms heterochiral rippled beta-sheet, includes hexafluoroisopropanol | 分子名称: | 1,1,1,3,3,3-hexafluoropropan-2-ol, Racemic mixture of amyloid beta segment 35-MVGGVV-40 | 著者 | Sawaya, M.R, Raskatov, J.A, Hazari, A. | 登録日 | 2023-06-21 | 公開日 | 2023-11-29 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.101 Å) | 主引用文献 | Racemic Peptides from Amyloid beta and Amylin Form Rippled beta-Sheets Rather Than Pleated beta-Sheets. J.Am.Chem.Soc., 145, 2023
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4X0X
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7FSD
| Structure of liver pyruvate kinase in complex with allosteric modulator 44 | 分子名称: | (1M)-N-({4-[(3,4-dihydroxyphenyl)methyl]phenyl}methyl)-3',4,4',5-tetrahydroxy[1,1'-biphenyl]-2-sulfonamide, 1,6-di-O-phosphono-beta-D-fructofuranose, MAGNESIUM ION, ... | 著者 | Lulla, A, Nilsson, O, Brear, P, Nain-Perez, A, Grotli, M, Hyvonen, M. | 登録日 | 2022-12-18 | 公開日 | 2023-04-12 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (1.769 Å) | 主引用文献 | Tuning liver pyruvate kinase activity up or down with a new class of allosteric modulators. Eur.J.Med.Chem., 250, 2023
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8TFB
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6DR1
| YopH PTP1B Chimera 2 PTPase | 分子名称: | Targeted effector protein | 著者 | Morales, Y, Johnson, S.J, Hengge, A.C. | 登録日 | 2018-06-11 | 公開日 | 2018-08-29 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | A YopH PTP1B Chimera Shows the Importance of the WPD-Loop Sequence to the Activity, Structure, and Dynamics of Protein Tyrosine Phosphatases. Biochemistry, 57, 2018
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7FS2
| Structure of liver pyruvate kinase in complex with allosteric modulator 13 | 分子名称: | (1P)-3',4,4',5-tetrahydroxy-N-{[4-(3-hydroxybenzene-1-sulfonyl)phenyl]methyl}[1,1'-biphenyl]-2-sulfonamide, 1,6-di-O-phosphono-beta-D-fructofuranose, MAGNESIUM ION, ... | 著者 | Lulla, A, Nilsson, O, Brear, P, Nain-Perez, A, Grotli, M, Hyvonen, M. | 登録日 | 2022-12-18 | 公開日 | 2023-04-12 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (2.374 Å) | 主引用文献 | Tuning liver pyruvate kinase activity up or down with a new class of allosteric modulators. Eur.J.Med.Chem., 250, 2023
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4WWV
| Aminopeptidase APDkam598 from the archaeon Desulfurococcus kamchatkensis | 分子名称: | Aminopeptidase from family M42 | 著者 | Petrova, T, Boyko, K.M, Rakitina, T.V, Korzhenevskiy, D.A, Gorbacheva, M.A, Popov, V.O. | 登録日 | 2014-11-12 | 公開日 | 2015-03-04 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (3.006 Å) | 主引用文献 | Structure of the dodecamer of the aminopeptidase APDkam598 from the archaeon Desulfurococcus kamchatkensis. Acta Crystallogr.,Sect.F, 71, 2015
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7FS8
| Structure of liver pyruvate kinase in complex with allosteric modulator 21 | 分子名称: | 1,6-di-O-phosphono-beta-D-fructofuranose, 4-[4-(3-aminobenzene-1-sulfonyl)piperazine-1-sulfonyl]benzene-1,2-diol, MAGNESIUM ION, ... | 著者 | Lulla, A, Nilsson, O, Brear, P, Nain-Perez, A, Grotli, M, Hyvonen, M. | 登録日 | 2022-12-18 | 公開日 | 2023-04-12 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (2.098 Å) | 主引用文献 | Tuning liver pyruvate kinase activity up or down with a new class of allosteric modulators. Eur.J.Med.Chem., 250, 2023
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7FSC
| Structure of liver pyruvate kinase in complex with allosteric modulator 42 | 分子名称: | 1,6-di-O-phosphono-beta-D-fructofuranose, MAGNESIUM ION, N-({4-[(3,4-dihydroxyphenyl)methyl]phenyl}methyl)benzenesulfonamide, ... | 著者 | Lulla, A, Nilsson, O, Brear, P, Nain-Perez, A, Grotli, M, Hyvonen, M. | 登録日 | 2022-12-18 | 公開日 | 2023-04-12 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (1.855 Å) | 主引用文献 | Tuning liver pyruvate kinase activity up or down with a new class of allosteric modulators. Eur.J.Med.Chem., 250, 2023
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5WN2
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6DRD
| RNA Pol II(G) | 分子名称: | DNA-directed RNA polymerase II subunit GRINL1A, DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11-a, ... | 著者 | Yu, X, Jishage, M, Shi, Y, Ganesan, S, Sali, A, Chait, B.T, Asturias, F, Roeder, R.G. | 登録日 | 2018-06-11 | 公開日 | 2019-06-12 | 最終更新日 | 2019-12-04 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Architecture of Pol II(G) and molecular mechanism of transcription regulation by Gdown1. Nat. Struct. Mol. Biol., 25, 2018
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6DRV
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8TGE
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6JCE
| NMR solution and X-ray crystal structures of a DNA containing both right-and left-handed parallel-stranded G-quadruplexes | 分子名称: | 29-mer DNA | 著者 | Winnerdy, F.R, Bakalar, B, Maity, A, Vandana, J.J, Mechulam, Y, Schmitt, E, Phan, A.T. | 登録日 | 2019-01-28 | 公開日 | 2019-07-10 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | NMR solution and X-ray crystal structures of a DNA molecule containing both right- and left-handed parallel-stranded G-quadruplexes. Nucleic Acids Res., 47, 2019
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5AQB
| DARPin-based Crystallization Chaperones exploit Molecular Geometry as a Screening Dimension in Protein Crystallography | 分子名称: | 3G61_DB15V4, GREEN FLUORESCENT PROTEIN | 著者 | Batyuk, A, Wu, Y, Honegger, A, Heberling, M, Plueckthun, A. | 登録日 | 2015-09-21 | 公開日 | 2016-03-23 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.37 Å) | 主引用文献 | Darpin-Based Crystallization Chaperones Exploit Molecular Geometry as a Screening Dimension in Protein Crystallography J.Mol.Biol., 428, 2016
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8PDG
| The phosphatase and C2 domains of SHIP1 with covalent Z2738285202 | 分子名称: | DIMETHYL SULFOXIDE, Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1, ~{N}-(8-chloranylquinolin-2-yl)propanamide | 著者 | Bradshaw, W.J, Moreira, T, Scacioc, A, Bountra, C, Chalk, R, von Delft, F, Brennan, P.E, Gileadi, O. | 登録日 | 2023-06-12 | 公開日 | 2023-06-28 | 最終更新日 | 2024-04-17 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Regulation of inositol 5-phosphatase activity by the C2 domain of SHIP1 and SHIP2. Structure, 32, 2024
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6H6D
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5F4V
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5ZA2
| Fox-4 beta-lactamase complexed with avibactam | 分子名称: | (2S,5R)-1-formyl-5-[(sulfooxy)amino]piperidine-2-carboxamide, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Beta-lactamase, ... | 著者 | Nukaga, M, Hoshino, T, Papp-Wallace, K.M, Bonomo, R.A. | 登録日 | 2018-02-06 | 公開日 | 2018-03-07 | 最終更新日 | 2018-05-09 | 実験手法 | X-RAY DIFFRACTION (1.503 Å) | 主引用文献 | Probing the Mechanism of Inactivation of the FOX-4 Cephamycinase by Avibactam Antimicrob. Agents Chemother., 62, 2018
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4WYY
| Crystal Structure of P. aeruginosa AmpC | 分子名称: | Beta-lactamase, DIMETHYL SULFOXIDE, GLYCEROL, ... | 著者 | Ferguson, A.D. | 登録日 | 2014-11-18 | 公開日 | 2015-08-05 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.28 Å) | 主引用文献 | 4,5-Disubstituted 6-Aryloxy-1,3-dihydrobenzo[c][1,2]oxaboroles Are Broad-Spectrum Serine beta-Lactamase Inhibitors. ACS Infect Dis, 1, 2015
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6TMV
| Structure of the chaperonin gp146 from the bacteriophage EL (Pseudomonas aeruginosa) in the apo state | 分子名称: | Putative GroEL-like chaperonine protein | 著者 | Bracher, A, Wang, H, Paul, S.S, Wischnewski, N, Hartl, F.U, Hayer-Hartl, M. | 登録日 | 2019-12-05 | 公開日 | 2020-04-22 | 最終更新日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (3.45 Å) | 主引用文献 | Structure and conformational cycle of a bacteriophage-encoded chaperonin. Plos One, 15, 2020
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7ZGQ
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7ZGR
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