5LF4
| Human 20S proteasome complex with Delanzomib at 2.0 Angstrom | 分子名称: | CHLORIDE ION, MAGNESIUM ION, PENTAETHYLENE GLYCOL, ... | 著者 | Schrader, J, Henneberg, F, Mata, R, Tittmann, K, Schneider, T.R, Stark, H, Bourenkov, G, Chari, A. | 登録日 | 2016-06-30 | 公開日 | 2016-08-17 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.99 Å) | 主引用文献 | The inhibition mechanism of human 20S proteasomes enables next-generation inhibitor design. Science, 353, 2016
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6TCA
| Phosphorylated p38 and MAPKAPK2 complex with inhibitor | 分子名称: | MAP kinase-activated protein kinase 2, Mitogen-activated protein kinase 14, N-[5-(dimethylsulfamoyl)-2-methylphenyl]-1-phenyl-5-propyl-1H-pyrazole-4-carboxamide | 著者 | Sok, P, Remenyi, A. | 登録日 | 2019-11-05 | 公開日 | 2020-07-22 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (3.7 Å) | 主引用文献 | MAP Kinase-Mediated Activation of RSK1 and MK2 Substrate Kinases. Structure, 28, 2020
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5LHX
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6TE4
| Structural insights into Pseudomonas aeruginosa Type six secretion system exported effector 8: Tse8 in complex with a peptide | 分子名称: | Pro-Pro-Leu-Ala-Ser-Lys, Tse8 | 著者 | Sainz-Polo, M.A, Capuni, R, Lucas, M, Altuna, J, Fucini, P, Montanchez, I, Albesa-Jove, D. | 登録日 | 2019-11-11 | 公開日 | 2020-11-04 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.29 Å) | 主引用文献 | Structural insights into Pseudomonas aeruginosaType six secretion system exported effector 8. J.Struct.Biol., 212, 2020
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1AO8
| DIHYDROFOLATE REDUCTASE COMPLEXED WITH METHOTREXATE, NMR, 21 STRUCTURES | 分子名称: | DIHYDROFOLATE REDUCTASE, METHOTREXATE | 著者 | Gargaro, A.R, Soteriou, A, Frenkiel, T.A, Bauer, C.J, Birdsall, B, Polshakov, V.I, Barsukov, I.L, Roberts, G.C.K, Feeney, J. | 登録日 | 1997-07-22 | 公開日 | 1998-02-25 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | The solution structure of the complex of Lactobacillus casei dihydrofolate reductase with methotrexate. J.Mol.Biol., 277, 1998
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5I3D
| Sulfolobus solfataricus beta-glycosidase - E387Y mutant | 分子名称: | 3,6,9,12,15,18,21-HEPTAOXATRICOSANE-1,23-DIOL, ACETATE ION, Beta-galactosidase | 著者 | Iglesias-Fernandez, J, Hancock, S.M, Lee, S.S, McAuley, K.E, Fordham-Skelton, A, Rovira, C, Davis, B.D. | 登録日 | 2016-02-10 | 公開日 | 2017-02-01 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.16 Å) | 主引用文献 | A front-face 'SNi synthase' engineered from a retaining 'double-SN2' hydrolase. Nat. Chem. Biol., 13, 2017
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6APF
| Trans-acting transferase from Disorazole synthase complexed with Citrate. | 分子名称: | CITRIC ACID, DisD protein, GLYCEROL, ... | 著者 | Mathews, I.I, Lyubimov, A, Soltis, M, Khosla, C, Cohen, A, Robbins, T. | 登録日 | 2017-08-17 | 公開日 | 2018-04-04 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.63 Å) | 主引用文献 | The Conformational Flexibility of the Acyltransferase from the Disorazole Polyketide Synthase Is Revealed by an X-ray Free-Electron Laser Using a Room-Temperature Sample Delivery Method for Serial Crystallography. Biochemistry, 56, 2017
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6GSS
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5I4Q
| Contact-dependent inhibition system from Escherichia coli NC101 - ternary CdiA/CdiI/EF-Tu complex (domains 2 and 3) | 分子名称: | CHLORIDE ION, Contact-dependent inhibitor A, Contact-dependent inhibitor I, ... | 著者 | Michalska, K, Stols, L, Eschenfeldt, W, Hayes, C.S, Goulding, C.W, Joachimiak, A, Midwest Center for Structural Genomics (MCSG), Structure-Function Analysis of Polymorphic CDI Toxin-Immunity Protein Complexes (UC4CDI) | 登録日 | 2016-02-12 | 公開日 | 2017-06-28 | 最終更新日 | 2019-12-25 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | Structure of a novel antibacterial toxin that exploits elongation factor Tu to cleave specific transfer RNAs. Nucleic Acids Res., 45, 2017
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5ISK
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5LLL
| Crystal structure of DACM wild type Transthyretin | 分子名称: | Transthyretin | 著者 | Sala, B.M, Ghadami, S.A, Bemporad, F, Chiti, F, Ricagno, S. | 登録日 | 2016-07-27 | 公開日 | 2017-06-07 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.42 Å) | 主引用文献 | FRET studies of various conformational states adopted by transthyretin. Cell. Mol. Life Sci., 74, 2017
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4Z10
| Inactive aurone synthase (polyphenol oxidase) co-crystallized with 1,4-resorcinol | 分子名称: | ACETATE ION, Aurone synthase, COPPER (II) ION, ... | 著者 | Molitor, C, Mauracher, S.G, Rompel, A. | 登録日 | 2015-03-26 | 公開日 | 2016-04-06 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.93 Å) | 主引用文献 | Inactive aurone synthase (polyphenol oxidase) co-crystallized with 1,4-resorcinol To Be Published
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6N0P
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1AVD
| THREE-DIMENSIONAL STRUCTURE OF THE TETRAGONAL CRYSTAL FORM OF EGG-WHITE AVIDIN IN ITS FUNCTIONAL COMPLEX WITH BIOTIN AT 2.7 ANGSTROMS RESOLUTION | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, AVIDIN, BIOTIN | 著者 | Pugliese, L, Coda, A, Malcovati, M, Bolognesi, M. | 登録日 | 1993-03-05 | 公開日 | 1994-01-31 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Three-dimensional structure of the tetragonal crystal form of egg-white avidin in its functional complex with biotin at 2.7 A resolution. J.Mol.Biol., 231, 1993
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5LL9
| Crystal structure of human carbonic anhydrase isozyme XII with 4-(1H-benzimidazol-1-ylacetyl)-2-chlorobenzenesulfonamide | 分子名称: | 1,2-ETHANEDIOL, 4-[2-(benzimidazol-1-yl)ethanoyl]-2-chloranyl-benzenesulfonamide, Carbonic anhydrase 12, ... | 著者 | Smirnov, A, Manakova, E, Grazulis, S. | 登録日 | 2016-07-27 | 公開日 | 2017-08-16 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | 主引用文献 | Combinatorial Design of Isoform-Selective N-Alkylated Benzimidazole-Based Inhibitors of Carbonic Anhydrases Chemistryselect, 2017
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7L5A
| Crystal structure of the photosensory module from Xanthomonas campestris bacteriophytochrome XccBphP in the Pfr state | 分子名称: | BILIVERDINE IX ALPHA, Bacteriophytochrome | 著者 | Otero, L.H, Antelo, G, Sanchez-Lamas, M, Klinke, S, Goldbaum, F.A, Rinaldi, J, Bonomi, H.R. | 登録日 | 2020-12-21 | 公開日 | 2021-12-29 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | 主引用文献 | Structural basis for the Pr-Pfr long-range signaling mechanism of a full-length bacterial phytochrome at the atomic level. Sci Adv, 7, 2021
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1AXI
| STRUCTURAL PLASTICITY AT THE HGH:HGHBP INTERFACE | 分子名称: | GROWTH HORMONE, GROWTH HORMONE RECEPTOR, SULFATE ION | 著者 | Atwell, S, Ultsch, M, De Vos, A.M, Wells, J.A. | 登録日 | 1997-10-15 | 公開日 | 1998-01-28 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structural plasticity in a remodeled protein-protein interface. Science, 278, 1997
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5LM8
| Crystal structure of a laccase-like multicopper oxidase McoG from from Aspergillus niger | 分子名称: | 'Multicopper oxidase, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Ferraroni, M, Briganti, F, Tamayo-Ramos, J.A, van Berkel, W.J.H, Westphal, A.H. | 登録日 | 2016-07-29 | 公開日 | 2017-05-03 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Structure and function of Aspergillus niger laccase McoG Biocatalysis, 2017
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7L59
| Crystal structure of the dark-adapted full-length bacteriophytochrome XccBphP-G454E variant from Xanthomonas campestris in the Pfr state | 分子名称: | BILIVERDINE IX ALPHA, Bacteriophytochrome | 著者 | Otero, L.H, Antelo, G, Sanchez-Lamas, M, Klinke, S, Goldbaum, F.A, Rinaldi, J, Bonomi, H.R. | 登録日 | 2020-12-21 | 公開日 | 2021-12-29 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.68 Å) | 主引用文献 | Structural basis for the Pr-Pfr long-range signaling mechanism of a full-length bacterial phytochrome at the atomic level. Sci Adv, 7, 2021
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1AVH
| CRYSTAL AND MOLECULAR STRUCTURE OF HUMAN ANNEXIN V AFTER REFINEMENT. IMPLICATIONS FOR STRUCTURE, MEMBRANE BINDING AND ION CHANNEL FORMATION OF THE ANNEXIN FAMILY OF PROTEINS | 分子名称: | ANNEXIN V, CALCIUM ION, SULFATE ION | 著者 | Huber, R, Berendes, R, Burger, A, Schneider, M, Karshikov, A, Luecke, H, Roemisch, J, Paques, E. | 登録日 | 1991-10-17 | 公開日 | 1994-01-31 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Crystal and molecular structure of human annexin V after refinement. Implications for structure, membrane binding and ion channel formation of the annexin family of proteins. J.Mol.Biol., 223, 1992
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6GFX
| pVHL:EloB:EloC in complex with modified HIF-1a CODD peptide containing (3R,4S)-3-fluoro-4-hydroxyproline (ligand 13a) | 分子名称: | Elongin-B, Elongin-C, FLUORINATED HYPOXIA-INDUCIBLE FACTOR 1 ALPHA PEPTIDE, ... | 著者 | Castro, G.V, Testa, A, Ciulli, A. | 登録日 | 2018-05-02 | 公開日 | 2018-07-11 | 最終更新日 | 2024-07-10 | 実験手法 | X-RAY DIFFRACTION (1.83 Å) | 主引用文献 | 3-Fluoro-4-hydroxyprolines: Synthesis, Conformational Analysis, and Stereoselective Recognition by the VHL E3 Ubiquitin Ligase for Targeted Protein Degradation. J. Am. Chem. Soc., 140, 2018
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5LNK
| Entire ovine respiratory complex I | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE, 4'-PHOSPHOPANTETHEINE, ... | 著者 | Fiedorczuk, K, Letts, J.A, Kaszuba, K, Sazanov, L.A. | 登録日 | 2016-08-04 | 公開日 | 2016-11-23 | 最終更新日 | 2021-06-02 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Atomic structure of the entire mammalian mitochondrial complex I. Nature, 538, 2016
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1ATG
| AZOTOBACTER VINELANDII PERIPLASMIC MOLYBDATE-BINDING PROTEIN | 分子名称: | 1,2-ETHANEDIOL, ACETATE ION, PERIPLASMIC MOLYBDATE-BINDING PROTEIN, ... | 著者 | Lawson, D.M, Pau, R.N, Williams, C.E.M, Mitchenall, L.A. | 登録日 | 1997-08-14 | 公開日 | 1998-10-14 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | 主引用文献 | Ligand size is a major determinant of specificity in periplasmic oxyanion-binding proteins: the 1.2 A resolution crystal structure of Azotobacter vinelandii ModA. Structure, 6, 1998
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4Y4O
| Crystal structure of the Thermus thermophilus 70S ribosome with rRNA modifications and bound to protein Y (YfiA) at 2.3A resolution | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 16S Ribosomal RNA, 23S Ribosomal RNA, ... | 著者 | Polikanov, Y.S, Melnikov, S.V, Soll, D, Steitz, T.A. | 登録日 | 2015-02-10 | 公開日 | 2015-03-18 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structural insights into the role of rRNA modifications in protein synthesis and ribosome assembly. Nat.Struct.Mol.Biol., 22, 2015
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5I3V
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