4YO3
| Enteroaggregative Escherichia Coli TssA N-terminal fragment | 分子名称: | TssA | 著者 | Durand, E, Zoued, A, Spinelli, S, Douzi, B, Brunet, Y.R, Bebeacua, C, Legrand, P, Journet, L, Mignot, T, Cambillau, C, Cascales, E. | 登録日 | 2015-03-11 | 公開日 | 2016-02-17 | 最終更新日 | 2017-08-30 | 実験手法 | X-RAY DIFFRACTION (3.37 Å) | 主引用文献 | Priming and polymerization of a bacterial contractile tail structure. Nature, 531, 2016
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4YO5
| EAEC T6SS TssA-Cterminus | 分子名称: | TssA | 著者 | Durand, E, Zoued, A, Spinelli, S, Douzi, B, Brunet, Y.R, Bebeacua, C, Legrand, P, Journet, L, Mignot, T, Cambillau, C, Cascales, E. | 登録日 | 2015-03-11 | 公開日 | 2016-02-17 | 最終更新日 | 2017-06-14 | 実験手法 | X-RAY DIFFRACTION (3.35 Å) | 主引用文献 | Priming and polymerization of a bacterial contractile tail structure. Nature, 531, 2016
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3U66
| Crystal structure of T6SS SciP/TssL from Escherichia Coli Enteroaggregative 042 | 分子名称: | GLYCEROL, Putative type VI secretion protein | 著者 | Durand, E, Aschtgen, M.S, Zoued, A, Spinelli, S, Watson, P.J.H, Cambillau, C, Cascales, E. | 登録日 | 2011-10-12 | 公開日 | 2012-03-07 | 最終更新日 | 2017-11-08 | 実験手法 | X-RAY DIFFRACTION (2.63 Å) | 主引用文献 | Structural characterization and oligomerization of the TssL protein, a component shared by bacterial type VI and type IVb secretion systems. J.Biol.Chem., 287, 2012
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4Y7M
| T6SS protein TssM C-terminal domain (835-1129) from EAEC | 分子名称: | Hi113 protein, SULFATE ION, Type VI secretion protein IcmF | 著者 | Nguyen, V.S, Spinelli, S, Durand, E, Roussel, A, Cambillau, C. | 登録日 | 2015-02-15 | 公開日 | 2015-08-05 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.92 Å) | 主引用文献 | Biogenesis and structure of a type VI secretion membrane core complex. Nature, 523, 2015
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4Y7L
| T6SS protein TssM C-terminal domain (869-1107) from EAEC | 分子名称: | GLYCEROL, Type VI secretion protein IcmF, ZINC ION | 著者 | Nguyen, V.S, Spinelli, S, Durand, E, Roussel, A, Cambillau, C. | 登録日 | 2015-02-15 | 公開日 | 2015-08-05 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.51 Å) | 主引用文献 | Biogenesis and structure of a type VI secretion membrane core complex. Nature, 523, 2015
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4Y7O
| T6SS protein TssM C-terminal domain (869-1107) from EAEC | 分子名称: | Type VI secretion protein IcmF, Type VI secretion system protein VasD, ZINC ION | 著者 | Nguyen, V.S, Spinelli, S, Durand, E, Roussel, A, Cambillau, C. | 登録日 | 2015-02-15 | 公開日 | 2015-08-05 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.24 Å) | 主引用文献 | Biogenesis and structure of a type VI secretion membrane core complex. Nature, 523, 2015
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5M30
| Structure of TssK from T6SS EAEC in complex with nanobody nb18 | 分子名称: | Anti-vesicular stomatitis virus N VHH, Type VI secretion protein | 著者 | Nguyen, V.S, Cambillau, C, Spinelli, C, Desmyter, A, Legrand, P, Cascales, E. | 登録日 | 2016-10-13 | 公開日 | 2017-06-21 | 最終更新日 | 2017-09-06 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Type VI secretion TssK baseplate protein exhibits structural similarity with phage receptor-binding proteins and evolved to bind the membrane complex. Nat Microbiol, 2, 2017
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5M2Y
| Structure of TssK C-terminal domain from E. coli T6SS | 分子名称: | TssK C | 著者 | Cambillau, C, Nguyen, V.S, Spinelli, S, Desmyter, A, Legrand, P. | 登録日 | 2016-10-13 | 公開日 | 2017-06-28 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.61 Å) | 主引用文献 | Type VI secretion TssK baseplate protein exhibits structural similarity with phage receptor-binding proteins and evolved to bind the membrane complex. Nat Microbiol, 2, 2017
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5M2W
| Structure of nanobody nb18 raised against TssK from E. coli T6SS | 分子名称: | Llama nanobody nb8 against TssK from T6SS, SULFATE ION | 著者 | Cambillau, C, Nguyen, V.S, Spinelli, S, Desmyter, A. | 登録日 | 2016-10-13 | 公開日 | 2017-06-28 | 最終更新日 | 2017-08-30 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Type VI secretion TssK baseplate protein exhibits structural similarity with phage receptor-binding proteins and evolved to bind the membrane complex. Nat Microbiol, 2, 2017
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5MWN
| Structure of the EAEC T6SS component TssK N-terminal domain in complex with llama nanobodies nbK18 and nbK27 | 分子名称: | PHOSPHATE ION, Type VI secretion protein, llama nanobody raised against TssK, ... | 著者 | Cambillau, C, Nguyen, V.S, Spinelli, S, Legrand, P. | 登録日 | 2017-01-18 | 公開日 | 2017-06-28 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Type VI secretion TssK baseplate protein exhibits structural similarity with phage receptor-binding proteins and evolved to bind the membrane complex. Nat Microbiol, 2, 2017
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3OAW
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6CHC
| JzTx-V toxin peptide, wild-type | 分子名称: | Beta/kappa-theraphotoxin-Cg2a | 著者 | Jordan, J.B. | 登録日 | 2018-02-22 | 公開日 | 2018-05-16 | 実験手法 | SOLUTION NMR | 主引用文献 | Pharmacological characterization of potent and selective NaV1.7 inhibitors engineered from Chilobrachys jingzhao tarantula venom peptide JzTx-V. PLoS ONE, 13, 2018
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6CNU
| Crystal Structure of JzTX-V | 分子名称: | BROMIDE ION, GLYCEROL, JzTx-V, ... | 著者 | Min, X, Wang, Z. | 登録日 | 2018-03-09 | 公開日 | 2019-03-06 | 最終更新日 | 2020-03-04 | 実験手法 | X-RAY DIFFRACTION (1.05 Å) | 主引用文献 | Discovery of Tarantula Venom-Derived NaV1.7-Inhibitory JzTx-V Peptide 5-Br-Trp24 Analogue AM-6120 with Systemic Block of Histamine-Induced Pruritis. J. Med. Chem., 61, 2018
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3PRE
| Quinazolines with intra-molecular hydrogen bonding scaffold (iMHBS) as PI3K/mTOR dual inhibitors. | 分子名称: | 2-amino-8-(trans-4-methoxycyclohexyl)-4-methyl-6-(1H-pyrazol-3-yl)pyrido[2,3-d]pyrimidin-7(8H)-one, Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 著者 | Knighton, D.R, Greasley, S.E, Rodgers, C.M.-L. | 登録日 | 2010-11-29 | 公開日 | 2011-02-09 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.91 Å) | 主引用文献 | Quinazolines with intra-molecular hydrogen bonding scaffold (iMHBS) as PI3K/mTOR dual inhibitors. Bioorg.Med.Chem.Lett., 21, 2011
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3PRZ
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3PS6
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6CGW
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8DNT
| SARS-CoV-2 specific T cell receptor | 分子名称: | Beta-2-microglobulin, MHC class I antigen alpha chain, Nucleoprotein, ... | 著者 | Gallagher, D.T, Wu, D, Gowthaman, R, Pierce, B.G, Mariuzza, R.A, Weng, N.P. | 登録日 | 2022-07-11 | 公開日 | 2023-07-19 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (3.18 Å) | 主引用文献 | SARS-CoV-2 infection establishes a stable and age-independent CD8 + T cell response against a dominant nucleocapsid epitope using restricted T cell receptors. Nat Commun, 14, 2023
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3G0E
| KIT kinase domain in complex with sunitinib | 分子名称: | Mast/stem cell growth factor receptor, N-[2-(diethylamino)ethyl]-5-[(Z)-(5-fluoro-2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carbo xamide | 著者 | Gajiwala, K.S, Wu, J.C, Lunney, E.A, Gemetri, G.D. | 登録日 | 2009-01-27 | 公開日 | 2009-02-24 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | KIT kinase mutants show unique mechanisms of drug resistance to imatinib and sunitinib in gastrointestinal stromal tumor patients. Proc.Natl.Acad.Sci.USA, 106, 2009
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3G0F
| KIT kinase domain mutant D816H in complex with sunitinib | 分子名称: | Mast/stem cell growth factor receptor, N-[2-(diethylamino)ethyl]-5-[(Z)-(5-fluoro-2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carbo xamide, SULFATE ION | 著者 | Gajiwala, K.S, Wu, J.C, Lunney, E.A, Demetri, G.D. | 登録日 | 2009-01-27 | 公開日 | 2009-02-24 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | KIT kinase mutants show unique mechanisms of drug resistance to imatinib and sunitinib in gastrointestinal stromal tumor patients. Proc.Natl.Acad.Sci.USA, 106, 2009
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