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4JWF
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BU of 4jwf by Molmil
Crystal structure of spTrm10(74)-SAH complex
分子名称: ACETIC ACID, S-ADENOSYL-L-HOMOCYSTEINE, tRNA (guanine(9)-N1)-methyltransferase
著者Yan, W, Shao, Z.
登録日2013-03-27
公開日2013-10-16
最終更新日2014-02-12
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal structure of tRNA m1G9 methyltransferase Trm10: insight into the catalytic mechanism and recognition of tRNA substrate.
Nucleic Acids Res., 42, 2014
4JWH
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BU of 4jwh by Molmil
Crystal structure of spTrm10(Full length)-SAH complex
分子名称: S-ADENOSYL-L-HOMOCYSTEINE, tRNA (guanine(9)-N1)-methyltransferase
著者Yan, W, Shao, Z.
登録日2013-03-27
公開日2013-10-16
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.04 Å)
主引用文献Crystal structure of tRNA m1G9 methyltransferase Trm10: insight into the catalytic mechanism and recognition of tRNA substrate.
Nucleic Acids Res., 42, 2014
4JWJ
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BU of 4jwj by Molmil
Crystal structure of scTrm10(84)-SAH complex
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, S-ADENOSYL-L-HOMOCYSTEINE, SULFATE ION, ...
著者Yan, W, Shao, Z.
登録日2013-03-27
公開日2013-10-16
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.76 Å)
主引用文献Crystal structure of tRNA m1G9 methyltransferase Trm10: insight into the catalytic mechanism and recognition of tRNA substrate.
Nucleic Acids Res., 42, 2014
4JWG
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BU of 4jwg by Molmil
Crystal structure of spTrm10(74)
分子名称: ACETIC ACID, tRNA (guanine(9)-N1)-methyltransferase
著者Yan, W, Shao, Z.
登録日2013-03-27
公開日2013-10-16
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal structure of tRNA m1G9 methyltransferase Trm10: insight into the catalytic mechanism and recognition of tRNA substrate.
Nucleic Acids Res., 42, 2014
5VK0
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BU of 5vk0 by Molmil
Crystal structure of human MDM2 in complex with a 12-mer lysine-cysteine side chain dithiocarbamate stapled peptide inhibitor PMI
分子名称: CHLORIDE ION, E3 ubiquitin-protein ligase Mdm2, Lysine-cysteine side chain dithiocarbamate stapled peptide inhibitor PMI
著者Tolbert, W.D, Gohain, N, Pazgier, M.
登録日2017-04-20
公開日2018-04-25
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Dithiocarbamate-inspired side chain stapling chemistry for peptide drug design.
Chem Sci, 10, 2019
5VK1
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BU of 5vk1 by Molmil
Crystal structure of human MDM4 in complex with a 12-mer lysine-cysteine side chain dithiocarbamate stapled peptide inhibitor PMI
分子名称: Lysine-cysteine side chain dithiocarbamate stapled peptide inhibitor PMI, Protein Mdm4
著者Tolbert, W.D, Gohain, N, Pazgier, M.
登録日2017-04-20
公開日2018-04-25
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.69 Å)
主引用文献Dithiocarbamate-inspired side chain stapling chemistry for peptide drug design.
Chem Sci, 10, 2019
5GXO
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BU of 5gxo by Molmil
Discovery of a compound that activates SIRT3 to deacetylate Manganese Superoxide Dismutase
分子名称: MANGANESE (II) ION, Superoxide dismutase [Mn], mitochondrial
著者Lu, J, Li, J, Wu, M, Wang, J, Xia, Q.
登録日2016-09-19
公開日2017-08-09
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献A small molecule activator of SIRT3 promotes deacetylation and activation of manganese superoxide dismutase.
Free Radic. Biol. Med., 112, 2017
6LJS
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BU of 6ljs by Molmil
Crystal structure of human FABP4 in complex with a novel inhibitor
分子名称: 1,2-ETHANEDIOL, 2-[(2-phenylphenyl)amino]benzoic acid, Fatty acid-binding protein, ...
著者Su, H.X, Zhang, X.L, Li, M.J, Xu, Y.C.
登録日2019-12-17
公開日2020-04-15
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Exploration of Fragment Binding Poses Leading to Efficient Discovery of Highly Potent and Orally Effective Inhibitors of FABP4 for Anti-inflammation.
J.Med.Chem., 63, 2020
6LJU
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BU of 6lju by Molmil
Crystal structure of human FABP4 in complex with a novel inhibitor
分子名称: 1,2-ETHANEDIOL, 2-[[3-chloranyl-4-(methylamino)-2-phenyl-phenyl]amino]benzoic acid, Fatty acid-binding protein, ...
著者Su, H.X, Zhang, X.L, Li, M.J, Xu, Y.C.
登録日2019-12-17
公開日2020-04-15
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Exploration of Fragment Binding Poses Leading to Efficient Discovery of Highly Potent and Orally Effective Inhibitors of FABP4 for Anti-inflammation.
J.Med.Chem., 63, 2020
6LJX
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BU of 6ljx by Molmil
Crystal structure of human FABP4 in complex with a novel inhibitor
分子名称: 2-phenylazanylbenzoic acid, Fatty acid-binding protein, adipocyte
著者Su, H.X, Zhang, X.L, Li, M.J, Xu, Y.C.
登録日2019-12-17
公開日2020-04-15
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Exploration of Fragment Binding Poses Leading to Efficient Discovery of Highly Potent and Orally Effective Inhibitors of FABP4 for Anti-inflammation.
J.Med.Chem., 63, 2020
6LJV
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BU of 6ljv by Molmil
Crystal structure of human FABP4 in complex with a novel inhibitor
分子名称: 2-[[3-chloranyl-2-(2,3-dihydro-1-benzofuran-5-yl)phenyl]amino]benzoic acid, Fatty acid-binding protein, adipocyte
著者Su, H.X, Zhang, X.L, Li, M.J, Xu, Y.C.
登録日2019-12-17
公開日2020-04-15
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.401 Å)
主引用文献Exploration of Fragment Binding Poses Leading to Efficient Discovery of Highly Potent and Orally Effective Inhibitors of FABP4 for Anti-inflammation.
J.Med.Chem., 63, 2020
6LJW
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BU of 6ljw by Molmil
Crystal structure of human FABP4 in complex with a novel inhibitor
分子名称: 1,2-ETHANEDIOL, 2-phenylazanylbenzoic acid, Fatty acid-binding protein, ...
著者Su, H.X, Zhang, X.L, Li, M.J, Xu, Y.C.
登録日2019-12-17
公開日2020-04-15
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Exploration of Fragment Binding Poses Leading to Efficient Discovery of Highly Potent and Orally Effective Inhibitors of FABP4 for Anti-inflammation.
J.Med.Chem., 63, 2020
6LJT
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BU of 6ljt by Molmil
Crystal structure of human FABP4 in complex with a novel inhibitor
分子名称: 1,2-ETHANEDIOL, 2-[(3-chloranyl-2-phenyl-phenyl)amino]benzoic acid, Fatty acid-binding protein, ...
著者Su, H.X, Zhang, X.L, Li, M.J, Xu, Y.C.
登録日2019-12-17
公開日2020-04-15
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Exploration of Fragment Binding Poses Leading to Efficient Discovery of Highly Potent and Orally Effective Inhibitors of FABP4 for Anti-inflammation.
J.Med.Chem., 63, 2020
8SJW
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BU of 8sjw by Molmil
[4T28] Self-assembling right-handed tensegrity triangle with 28 interjunction base pairs and R3 symmetry
分子名称: DNA (28-MER), DNA (5'-D(*GP*AP*AP*CP*TP*GP*CP*CP*TP*GP*AP*AP*TP*TP*AP*CP*TP*GP*AP*CP*CP*G)-3'), DNA (5'-D(*TP*CP*AP*TP*CP*AP*GP*TP*GP*GP*CP*AP*GP*T)-3'), ...
著者Janowski, J, Vecchioni, S, Sha, R, Ohayon, Y.P.
登録日2023-04-18
公開日2024-04-24
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (7.64 Å)
主引用文献Engineering tertiary chirality in helical biopolymers.
Proc.Natl.Acad.Sci.USA, 121, 2024
8SJR
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BU of 8sjr by Molmil
[3T17] Self-assembling right-handed tensegrity triangle with 17 interjunction base pairs and R3 symmetry
分子名称: DNA (5'-D(*CP*AP*GP*CP*AP*GP*CP*CP*TP*GP*AP*AP*TP*AP*CP*CP*GP*CP*A)-3'), DNA (5'-D(*TP*GP*CP*GP*CP*TP*GP*TP*GP*GP*CP*TP*GP*C)-3'), DNA (5'-D(P*GP*CP*GP*GP*TP*AP*TP*TP*CP*AP*CP*CP*AP*CP*GP*AP*T)-3'), ...
著者Janowski, J, Vecchioni, S, Sha, R, Ohayon, Y.P.
登録日2023-04-18
公開日2024-04-24
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (5.25 Å)
主引用文献Engineering tertiary chirality in helical biopolymers.
Proc.Natl.Acad.Sci.USA, 121, 2024
8SJM
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BU of 8sjm by Molmil
[3T12] Self-assembling left-handed tensegrity triangle with 12 interjunction base pairs and R3 symmetry
分子名称: DNA (5'-D(*CP*AP*GP*CP*AP*TP*CP*GP*CP*CP*TP*GP*AP*CP*A)-3'), DNA (5'-D(*TP*GP*CP*TP*CP*GP*CP*AP*TP*GP*TP*GP*GP*CP*GP*AP*TP*GP*C)-3'), DNA (5'-D(P*CP*GP*TP*GP*GP*AP*CP*AP*TP*GP*CP*GP*AP*G)-3'), ...
著者Janowski, J, Vecchioni, S, Sha, R, Ohayon, Y.P.
登録日2023-04-18
公開日2024-04-24
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (8.08 Å)
主引用文献Engineering tertiary chirality in helical biopolymers.
Proc.Natl.Acad.Sci.USA, 121, 2024
8SJQ
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BU of 8sjq by Molmil
[3T16] Self-assembling right-handed tensegrity triangle with 16 interjunction base pairs and R3 symmetry
分子名称: DNA (5'-D(*CP*AP*GP*CP*AP*TP*GP*CP*CP*TP*GP*AP*TP*AP*CP*CP*GP*CP*A)-3'), DNA (5'-D(*TP*GP*CP*GP*CP*TP*GP*TP*GP*GP*CP*AP*TP*GP*C)-3'), DNA (5'-D(P*TP*CP*GP*TP*GP*GP*AP*CP*AP*GP*CP*G)-3'), ...
著者Janowski, J, Vecchioni, S, Sha, R, Ohayon, Y.P.
登録日2023-04-18
公開日2024-04-24
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (6.19 Å)
主引用文献Engineering tertiary chirality in helical biopolymers.
Proc.Natl.Acad.Sci.USA, 121, 2024
8SJS
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BU of 8sjs by Molmil
[3T18] Self-assembling right-handed tensegrity triangle with 18 interjunction base pairs and P63 symmetry
分子名称: DNA (5'-D(*CP*AP*GP*AP*GP*CP*CP*TP*GP*AP*CP*AP*TP*AP*CP*CP*GP*CP*A)-3'), DNA (5'-D(*TP*GP*CP*GP*CP*TP*GP*TP*GP*GP*CP*TP*C)-3'), DNA (5'-D(P*TP*CP*GP*TP*GP*GP*AP*CP*AP*GP*CP*G)-3'), ...
著者Janowski, J, Vecchioni, S, Sha, R, Ohayon, Y.P.
登録日2023-04-18
公開日2024-04-24
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (6.31 Å)
主引用文献Engineering tertiary chirality in helical biopolymers.
Proc.Natl.Acad.Sci.USA, 121, 2024
8SJN
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BU of 8sjn by Molmil
[3T13] Self-assembling left-handed tensegrity triangle with 13 interjunction base pairs and R3 symmetry
分子名称: DNA (5'-D(*CP*AP*GP*CP*AP*TP*CP*GP*CP*CP*TP*GP*AP*CP*TP*AP*CP*A)-3'), DNA (5'-D(*TP*GP*CP*TP*CP*GP*CP*TP*GP*TP*GP*GP*CP*GP*AP*TP*GP*C)-3'), DNA (5'-D(P*CP*GP*TP*GP*GP*AP*CP*AP*GP*CP*GP*AP*G)-3'), ...
著者Janowski, J, Vecchioni, S, Sha, R, Ohayon, Y.P.
登録日2023-04-18
公開日2024-04-24
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (7.3 Å)
主引用文献Engineering tertiary chirality in helical biopolymers.
Proc.Natl.Acad.Sci.USA, 121, 2024
8SJU
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BU of 8sju by Molmil
[4T17] Self-assembling right-handed four-turn tensegrity triangle with 17 interjunction base pairs and R3 symmetry
分子名称: DNA (25-MER), DNA (5'-D(*GP*AP*AP*AP*AP*AP*CP*AP*CP*TP*GP*CP*CP*TP*GP*AP*AP*TP*AP*CP*CP*GP*CP*A)-3'), DNA (5'-D(P*GP*CP*GP*GP*TP*AP*TP*TP*CP*AP*CP*CP*AP*CP*GP*AP*T)-3'), ...
著者Janowski, J, Vecchioni, S, Sha, R, Ohayon, Y.P.
登録日2023-04-18
公開日2024-04-24
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (7.14 Å)
主引用文献Engineering tertiary chirality in helical biopolymers.
Proc.Natl.Acad.Sci.USA, 121, 2024
8SJP
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BU of 8sjp by Molmil
[3T15] Self-assembling DNA motif with 15 base pairs between junctions and P32 symmetry
分子名称: DNA (5'-D(*CP*AP*GP*CP*TP*GP*AP*CP*CP*TP*GP*AP*CP*TP*CP*AP*CP*A)-3'), DNA (5'-D(*TP*GP*CP*TP*CP*CP*TP*GP*TP*GP*GP*TP*CP*AP*GP*C)-3'), DNA (5'-D(P*CP*GP*AP*TP*GP*GP*AP*CP*AP*GP*GP*GP*G)-3'), ...
著者Vecchioni, S, Janowski, J, Sha, R, Ohayon, Y.P.
登録日2023-04-18
公開日2024-04-24
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (5.22 Å)
主引用文献Engineering tertiary chirality in helical biopolymers.
Proc.Natl.Acad.Sci.USA, 121, 2024
8SJV
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BU of 8sjv by Molmil
[4T24] Self-assembling left-handed tensegrity triangle with 24 interjunction base pairs and R3 symmetry
分子名称: DNA (5'-D(P*CP*TP*TP*GP*TP*AP*GP*TP*CP*TP*CP*AP*CP*CP*AP*CP*TP*GP*TP*GP*AP*TP*GP*T)-3'), DNA (5'-D(P*GP*AP*AP*CP*AP*CP*TP*CP*CP*TP*GP*AP*GP*AP*CP*TP*AP*CP*AP*A)-3'), DNA (5'-D(P*GP*AP*CP*AP*TP*CP*AP*CP*AP*GP*TP*GP*GP*AP*CP*TP*AP*CP*AP*AP*G)-3'), ...
著者Janowski, J, Vecchioni, S, Sha, R, Ohayon, Y.P.
登録日2023-04-18
公開日2024-04-24
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (8.59 Å)
主引用文献Engineering tertiary chirality in helical biopolymers.
Proc.Natl.Acad.Sci.USA, 121, 2024
8SL5
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BU of 8sl5 by Molmil
[2T13] Self-assembling left-handed two-turn tensegrity triangle with 13 interjunction base pairs and R3 symmetry
分子名称: DNA (5'-D(*GP*AP*GP*CP*CP*TP*GP*AP*CP*TP*AP*CP*A)-3'), DNA (5'-D(*TP*CP*TP*GP*TP*GP*GP*C)-3'), DNA (5'-D(P*CP*GP*TP*GP*GP*AP*CP*A)-3'), ...
著者Vecchioni, S, Janowski, J, Sha, R, Ohayon, Y.P.
登録日2023-04-21
公開日2024-04-24
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (6.55 Å)
主引用文献Engineering tertiary chirality in helical biopolymers.
Proc.Natl.Acad.Sci.USA, 121, 2024
8SJO
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BU of 8sjo by Molmil
[3T14] Self-assembling left-handed tensegrity triangle with 14 interjunction base pairs and R3 symmetry
分子名称: DNA (5'-D(P*CP*AP*CP*GP*TP*GP*GP*AP*CP*AP*GP*GP*AP*G)-3'), DNA (5'-D(P*CP*AP*GP*CP*TP*CP*AP*GP*CP*CP*TP*GP*AP*CP*TP*CP*A)-3'), DNA (5'-D(P*GP*TP*GP*AP*GP*TP*CP*TP*CP*CP*AP*CP*GP*T)-3'), ...
著者Janowski, J, Vecchioni, S, Sha, R, Ohayon, Y.P.
登録日2023-04-18
公開日2024-04-24
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (7.08 Å)
主引用文献Engineering tertiary chirality in helical biopolymers.
Proc.Natl.Acad.Sci.USA, 121, 2024
8SJT
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BU of 8sjt by Molmil
[3T14+10] Self-assembling left-handed tensegrity triangle with 14 interjunction base pairs and a 10 bp linker with R3 symmetry
分子名称: DNA (5'-D(*AP*CP*CP*TP*CP*CP*TP*GP*AP*GP*GP*TP*CP*GP*AP*GP*C)-3'), DNA (5'-D(*GP*AP*CP*TP*CP*TP*GP*CP*TP*A)-3'), DNA (5'-D(*GP*TP*TP*AP*GP*CP*AP*GP*AP*G)-3'), ...
著者Janowski, J, Vecchioni, S, Sha, R, Ohayon, Y.P.
登録日2023-04-18
公開日2024-04-24
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (9.38 Å)
主引用文献Engineering tertiary chirality in helical biopolymers.
Proc.Natl.Acad.Sci.USA, 121, 2024

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件を2024-05-15に公開中

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