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3DWH
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BU of 3dwh by Molmil
Structural and Functional Analysis of SRA domain
Descriptor: E3 ubiquitin-protein ligase UHRF1, GLYCEROL, SULFATE ION
Authors:Qian, C, Jakoncic, J, Zhou, M.
Deposit date:2008-07-22
Release date:2008-10-21
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structure and Hemimethylated CpG Binding of the SRA Domain from Human UHRF1.
J.Biol.Chem., 283, 2008
4N3W
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BU of 4n3w by Molmil
Crystal Structure of the Bromodomain-PHD Finger Module of Human Transcriptional Co-Activator CBP in complex with Acetylated Histone 4 Peptide (H4K20ac).
Descriptor: CREB-binding protein, Histone H4 peptide, ZINC ION
Authors:Plotnikov, A.N, Yang, S, Zhou, M.-M.
Deposit date:2013-10-07
Release date:2014-01-29
Last modified:2018-02-14
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural Insights into Acetylated-Histone H4 Recognition by the Bromodomain-PHD Finger Module of Human Transcriptional Coactivator CBP.
Structure, 22, 2014
6MNL
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BU of 6mnl by Molmil
NMR solution structures of second bromodomain of BRD4 with FOXO3a peptide
Descriptor: Bromodomain-containing protein 4, FOXO3a peptide
Authors:Zeng, L, Zhou, M.-M.
Deposit date:2018-10-02
Release date:2018-10-31
Last modified:2023-11-15
Method:SOLUTION NMR
Cite:Targeting the BRD4/FOXO3a/CDK6 axis sensitizes AKT inhibition in luminal breast cancer.
Nat Commun, 9, 2018
2RO1
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BU of 2ro1 by Molmil
NMR Solution Structures of Human KAP1 PHD finger-bromodomain
Descriptor: Transcription intermediary factor 1-beta, ZINC ION
Authors:Zeng, L, Yap, K.L, Ivanov, A.V, Wang, X, Mujtaba, S, Plotnikova, O, Rauscher, F.J.
Deposit date:2008-03-04
Release date:2008-05-20
Last modified:2022-03-16
Method:SOLUTION NMR
Cite:Structural insights into human KAP1 PHD finger-bromodomain and its role in gene silencing
Nat.Struct.Mol.Biol., 15, 2008
8I60
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BU of 8i60 by Molmil
Crystal structure of GAS41 YEATS domain in complex with histone H3K27cr
Descriptor: ALA-ARG-KCR-SER-ALA-PRO, GLYCEROL, SULFATE ION, ...
Authors:Konuma, T, Zhou, M.-M.
Deposit date:2023-01-26
Release date:2023-07-26
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Histone H3 lysine 27 crotonylation mediates gene transcriptional repression in chromatin.
Mol.Cell, 83, 2023
7CNA
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BU of 7cna by Molmil
Crystal structure of Spindlin1/C11orf84 complex bound to histone H3K4me3K9me3 peptide
Descriptor: ALA-ARG-THR-M3L-GLN-THR-ALA-ARG-M3L-SER-GLY, ALA-ARG-THR-M3L-GLN-THR-ALA-ARG-M3L-SER-THR, BENZAMIDINE, ...
Authors:Qian, C.M.
Deposit date:2020-07-30
Release date:2021-01-13
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structural mechanism of bivalent histone H3K4me3K9me3 recognition by the Spindlin1/C11orf84 complex in rRNA transcription activation.
Nat Commun, 12, 2021
5Z9C
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BU of 5z9c by Molmil
Solution NMR structures of BRD4 first bromodomain with small compound MMQO
Descriptor: 8-methoxy-6-methylquinolin-4(1H)-one, Bromodomain-containing protein 4
Authors:Zeng, L, Zhou, M.-M.
Deposit date:2018-02-02
Release date:2018-02-14
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:A New Quinoline BRD4 Inhibitor Targets a Distinct Latent HIV-1 Reservoir for Reactivation from Other "Shock" Drugs.
J. Virol., 92, 2018
3QB8
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BU of 3qb8 by Molmil
Paramecium Chlorella Bursaria Virus1 Putative ORF A654L is a Polyamine Acetyltransferase
Descriptor: A654L protein, COENZYME A, IMIDAZOLE
Authors:Charlop-Powers, Z, Zhou, M.-M, Jakoncic, J, Gurnon, J, Van Etten, J.
Deposit date:2011-01-12
Release date:2012-01-25
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Paramecium bursaria chlorella virus 1 encodes a polyamine acetyltransferase.
J. Biol. Chem., 287, 2012
4QB3
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BU of 4qb3 by Molmil
Crystal structure of the first bromodomain of human BRD4 in complex with Olinone
Descriptor: 1,2-ETHANEDIOL, Bromodomain-containing protein 4, N-[4-(1-oxo-1,2,3,4-tetrahydro-5H-pyrido[4,3-b]indol-5-yl)butyl]acetamide
Authors:Plotnikov, A.N, Joshua, J, Zhou, M.-M.
Deposit date:2014-05-06
Release date:2015-04-22
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (0.94 Å)
Cite:Selective chemical modulation of gene transcription favors oligodendrocyte lineage progression.
Chem.Biol., 21, 2014
2KTB
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BU of 2ktb by Molmil
Solution Structure of the Second Bromodomain of Human Polybromo in complex with an acetylated peptide from Histone 3
Descriptor: H3_Peptide, Protein polybromo-1
Authors:Charlop-Powers, Z, Zhang, Q, Zeng, L.
Deposit date:2010-01-26
Release date:2010-05-12
Last modified:2023-11-15
Method:SOLUTION NMR
Cite:Structural insights into selective histone H3 recognition by the human Polybromo bromodomain 2.
Cell Res., 20, 2010
2LXE
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BU of 2lxe by Molmil
S4wyild
Descriptor: Histone-lysine N-methyltransferase SUVR4
Authors:Kristiansen, P, Rahman, M.A, Aalen, R.B.
Deposit date:2012-08-20
Release date:2013-11-20
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:The arabidopsis histone methyltransferase SUVR4 binds ubiquitin via a domain with a four-helix bundle structure.
Biochemistry, 53, 2014
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