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4Y29
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BU of 4y29 by Molmil
Identification of a novel PPARg ligand that regulates metabolism
Descriptor: 1,2-dimethoxy-12-methyl[1,3]benzodioxolo[5,6-c]phenanthridin-12-ium, Peptide from Nuclear receptor coactivator 1, Peroxisome proliferator-activated receptor gamma
Authors:Wang, R, Li, Y.
Deposit date:2015-02-09
Release date:2015-09-09
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:Selective targeting of PPAR gamma by the natural product chelerythrine with a unique binding mode and improved antidiabetic potency.
Sci Rep, 5, 2015
7C6Q
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BU of 7c6q by Molmil
Novel natural PPARalpha agonist with a unique binding mode
Descriptor: 13-methyl[1,3]benzodioxolo[5,6-c][1,3]dioxolo[4,5-i]phenanthridin-13-ium, LYS-ILE-LEU-HIS-ARG-LEU-LEU-GLN, Peroxisome proliferator-activated receptor alpha
Authors:Tian, S.Y, Wang, R, Zheng, W.L, Li, Y.
Deposit date:2020-05-22
Release date:2021-05-26
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.76 Å)
Cite:Structural Basis for PPARs Activation by The Dual PPAR alpha / gamma Agonist Sanguinarine: A Unique Mode of Ligand Recognition.
Molecules, 26, 2021

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