5ZFM
| Ketoreductase LbCR mutant - M6 | 分子名称: | 3-oxoacyl-acyl carrier protein reductase | 著者 | Gong, X.M, Zheng, G.W, Xu, J.H. | 登録日 | 2018-03-06 | 公開日 | 2019-01-16 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Development of an Engineered Ketoreductase with Simultaneously Improved Thermostability and Activity for Making a Bulky Atorvastatin Precursor Acs Catalysis, 9, 2019
|
|
5ZI0
| Ketoreductase LbCR mutant - M8 | 分子名称: | 3-oxoacyl-acyl carrier protein reductase | 著者 | Gong, X.M, Zheng, G.W, Xu, J.H. | 登録日 | 2018-03-14 | 公開日 | 2019-01-16 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (2.302 Å) | 主引用文献 | Development of an Engineered Ketoreductase with Simultaneously Improved Thermostability and Activity for Making a Bulky Atorvastatin Precursor Acs Catalysis, 9, 2019
|
|
6JIT
| Complex structure of an imine reductase at 2.05 Angstrom resolution | 分子名称: | 1-(2-phenylethyl)-3,4-dihydroisoquinoline, 6-phosphogluconate dehydrogenase NAD-binding protein, CHLORIDE ION, ... | 著者 | Li, H, Wu, L, Zheng, G.W, Zhou, J.H. | 登録日 | 2019-02-23 | 公開日 | 2020-02-26 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.052 Å) | 主引用文献 | Complex structure of an imine reductase at 2.05 Angstrom resolution To Be Published
|
|
6JIZ
| Apo structure of an imine reductase at 1.76 Angstrom resolution | 分子名称: | 1,2-ETHANEDIOL, 3-ethylheptane, 6-phosphogluconate dehydrogenase NAD-binding protein, ... | 著者 | Li, H, Wu, L, Zheng, G.W, Zhou, J.H. | 登録日 | 2019-02-24 | 公開日 | 2020-02-26 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (1.763 Å) | 主引用文献 | Apo structure of an imine reductase at 1.76 Angstrom resolution To Be Published
|
|
8HWY
| Ancestral imine reductase mutant N559_M6 | 分子名称: | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ancestral imine reductase mutant N559_M6 | 著者 | Zhu, X.X. | 登録日 | 2023-01-03 | 公開日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.32 Å) | 主引用文献 | The evolution of stereoselectivity in imine reductase To Be Published
|
|
8JYT
| Ancestral imine reducatase N560 | 分子名称: | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ancestra imine reductase | 著者 | Zhu, X.X. | 登録日 | 2023-07-03 | 公開日 | 2023-10-11 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.79 Å) | 主引用文献 | The structure of ancestral imine reductase N560. To Be Published
|
|
7Y8M
| Structure of ScIRED-R2-V3 from Streptomyces clavuligerus in complex with 5-(3-fluorophenyl)-3,4-dihydro-2H-pyrrole | 分子名称: | 2-[2,5-bis(fluoranyl)phenyl]pyrrolidine, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, reductase | 著者 | Zhang, L.L, Liu, W.D, Shi, M, Huang, J.W, Yang, Y, Chen, C.C, Guo, R.T. | 登録日 | 2022-06-24 | 公開日 | 2023-06-28 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.28 Å) | 主引用文献 | Engineered Imine Reductase for Larotrectinib Intermediate Manufacture Acs Catalysis, 12, 2022
|
|
8JKU
| Ancestal imine reductase | 分子名称: | Ancestral imine reductase N559, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | 著者 | Zhu, X.X, Zheng, G.W. | 登録日 | 2023-06-01 | 公開日 | 2023-08-09 | 実験手法 | X-RAY DIFFRACTION (2.57 Å) | 主引用文献 | Structure of ancestral imine reductase at 2.56 Angstroms resolution. To Be Published
|
|
7Y8L
| Structure of ScIRED-R2-V3 from Streptomyces clavuligerus in complex with 5-(2,5-difluorophenyl)-3,4-dihydro-2H-pyrrole | 分子名称: | 5-[2,5-bis(fluoranyl)phenyl]-3,4-dihydro-2~{H}-pyrrole, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | 著者 | Zhang, L.L, Liu, W.D, Shi, M, Huang, J.W, Yang, Y, Chen, C.C, Guo, R.T. | 登録日 | 2022-06-24 | 公開日 | 2023-06-28 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.41 Å) | 主引用文献 | Engineered Imine Reductase for Larotrectinib Intermediate Manufacture Acs Catalysis, 12, 2022
|
|
7Y8K
| Structure of ScIRED wild-type from Streptomyces clavuligerus | 分子名称: | Beta-hydroxyacid dehydrogenase, 3-hydroxyisobutyrate dehydrogenase | 著者 | Zhang, L.L, Liu, W.D, Shi, M, Huang, J.W, Yang, Y, Chen, C.C, Guo, R.T. | 登録日 | 2022-06-24 | 公開日 | 2023-03-22 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.08 Å) | 主引用文献 | Engineered Imine Reductase for Larotrectinib Intermediate Manufacture Acs Catalysis, 12, 2022
|
|
7Y8N
| Structure of ScIRED-R3-V4 from Streptomyces clavuligerus in complex with 5-(2,5-difluorophenyl)-3,4-dihydro-2H-pyrrole | 分子名称: | 5-[2,5-bis(fluoranyl)phenyl]-3,4-dihydro-2~{H}-pyrrole, Beta-hydroxyacid dehydrogenase, 3-hydroxyisobutyrate dehydrogenase, ... | 著者 | Zhang, L.L, Liu, W.D, Shi, M, Huang, J.W, Yang, Y, Chen, C.C, Guo, R.T. | 登録日 | 2022-06-24 | 公開日 | 2023-05-03 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Engineered Imine Reductase for Larotrectinib Intermediate Manufacture Acs Catalysis, 12, 2022
|
|
7Y8O
| Structure of ScIRED-R3-V4 from Streptomyces clavuligerus in complex with 5-(3-fluorophenyl)-3,4-dihydro-2H-pyrrole | 分子名称: | 2-[2,5-bis(fluoranyl)phenyl]pyrrolidine, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, SciR | 著者 | Zhang, L.L, Liu, W.D, Shi, M, Huang, J.W, Yang, Y, Chen, C.C, Guo, R.T. | 登録日 | 2022-06-24 | 公開日 | 2023-03-22 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structure of ScIRED-R3-V4 from Streptomyces clavuligerus in complex with 5-(3-fluorophenyl)-3,4-dihydro-2H-pyrrole to be published
|
|