7Y8K

Structure of ScIRED wild-type from Streptomyces clavuligerus

Summary for 7Y8K

• Entry DOI: 10.2210/pdb7y8k/pdb
• Descriptor: Beta-hydroxyacid dehydrogenase, 3-hydroxyisobutyrate dehydrogenase (2 entities in total)
• Functional Keywords: substrate binding, hydrolase
• Biological source: Streptomyces clavuligerus
• Total number of polymer chains: 2
• Total formula weight: 60937.11

Authors

Zhang, L.L.,Liu, W.D.,Shi, M.,Huang, J.W.,Yang, Y.,Chen, C.C.,Guo, R.T. (deposition date: 2022-06-24, release date: 2023-03-22, Last modification date: 2023-11-29)

• Primary citation: Chen, Q.,Li, B.B.,Zhang, L.,Chen, X.R.,Zhu, X.X.,Chen, F.F.,Shi, M.,Chen, C.C.,Yang, Y.,Guo, R.T.,Liu, W.,Xu, J.H.,Zheng, G.W.; Engineered Imine Reductase for Larotrectinib Intermediate Manufacture; Acs Catalysis, 12:14795-14803, 2022; DOI: 10.1021/acscatal.2c03783

Experimental method

X-RAY DIFFRACTION (2.08 Å)