7XNA
| Crystal structure of somatostatin receptor 2 (SSTR2) with peptide antagonist CYN 154806 | 分子名称: | CYN 154806, Somatostatin receptor type 2,Endo-1,4-beta-xylanase | 著者 | Zhao, W, Han, S, Qiu, N, Feng, W, Lu, M, Yang, D, Wang, M.-W, Wu, B, Zhao, Q. | 登録日 | 2022-04-28 | 公開日 | 2022-08-03 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | 主引用文献 | Structural insights into ligand recognition and selectivity of somatostatin receptors. Cell Res., 32, 2022
|
|
7XN9
| Crystal structure of SSTR2 and L-054,522 complex | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Somatostatin receptor type 2,Endo-1,4-beta-xylanase, tert-butyl (2S)-6-azanyl-2-[[(2R,3S)-3-(1H-indol-3-yl)-2-[[4-(2-oxidanylidene-3H-benzimidazol-1-yl)piperidin-1-yl]carbonylamino]butanoyl]amino]hexanoate | 著者 | Zhao, W, Han, S, Qiu, N, Feng, W, Lu, M, Yang, D, Wang, M.-W, Wu, B, Zhao, Q. | 登録日 | 2022-04-28 | 公開日 | 2022-08-03 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Structural insights into ligand recognition and selectivity of somatostatin receptors. Cell Res., 32, 2022
|
|
7XK8
| Cryo-EM structure of the Neuromedin U receptor 2 (NMUR2) in complex with G Protein and its endogeneous Peptide-Agonist NMU25 | 分子名称: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ... | 著者 | Zhao, W, Wenru, Z, Mu, W, Minmin, L, Shutian, C, Tingting, T, Gisela, S, Holger, W, Albert, B, Cuiying, Y, Xiaojing, C, Han, S, Wu, B, Zhao, Q. | 登録日 | 2022-04-19 | 公開日 | 2023-02-22 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Ligand recognition and activation of neuromedin U receptor 2. Nat Commun, 13, 2022
|
|
5JCB
| Microtubule depolymerizing agent podophyllotoxin derivative YJTSF1 | 分子名称: | (5R,5aR,8aS,9R)-9-[(4H-1,2,4-triazol-3-yl)sulfanyl]-5-(3,4,5-trimethoxyphenyl)-5,8,8a,9-tetrahydro-2H-furo[3',4':6,7]naphtho[2,3-d][1,3]dioxol-6(5aH)-one, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, ... | 著者 | Guan, Z, Zhao, W, Yin, P. | 登録日 | 2016-04-14 | 公開日 | 2017-09-27 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structural Insights into the Inhibition of Tubulin by the Antitumor Agent 4 beta-(1,2,4-triazol-3-ylthio)-4-deoxypodophyllotoxin. ACS Chem. Biol., 12, 2017
|
|
4UX5
| Structure of DNA complex of PCG2 | 分子名称: | 5'-D(*CP*AP*AP*TP*GP*AP*CP*GP*CP*GP*TP*AP*AP*GP)-3', 5'-D(*CP*TP*TP*AP*CP*GP*CP*GP*TP*CP*AP*TP*TP*GP)-3', TRANSCRIPTION FACTOR MBP1 | 著者 | Liu, J, Huang, J, Zhao, Y, Liu, H, Wang, D, Yang, J, Zhao, W, Taylor, I.A, Peng, Y. | 登録日 | 2014-08-19 | 公開日 | 2015-01-14 | 最終更新日 | 2015-02-04 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structural Basis of DNA Recognition by Pcg2 Reveals a Novel DNA Binding Mode for Winged Helix-Turn-Helix Domains. Nucleic Acids Res., 43, 2015
|
|
5H1B
| Human RAD51 presynaptic complex | 分子名称: | DNA (5'-D(P*TP*TP*TP*TP*TP*TP*TP*TP*T)-3'), DNA repair protein RAD51 homolog 1, MAGNESIUM ION, ... | 著者 | Xu, J, Zhao, L, Xu, Y, Zhao, W, Sung, P, Wang, H.W. | 登録日 | 2016-10-08 | 公開日 | 2016-12-21 | 最終更新日 | 2022-03-23 | 実験手法 | ELECTRON MICROSCOPY (4.4 Å) | 主引用文献 | Cryo-EM structures of human RAD51 recombinase filaments during catalysis of DNA-strand exchange Nat. Struct. Mol. Biol., 24, 2017
|
|
5H1C
| Human RAD51 post-synaptic complexes | 分子名称: | DNA (5'-D(P*AP*AP*AP*AP*AP*AP*AP*AP*A)-3'), DNA (5'-D(P*TP*TP*TP*TP*TP*TP*TP*TP*T)-3'), DNA repair protein RAD51 homolog 1, ... | 著者 | Xu, J, Zhao, L, Xu, Y, Zhao, W, Sung, P, Wang, H.W. | 登録日 | 2016-10-08 | 公開日 | 2016-12-21 | 最終更新日 | 2022-03-23 | 実験手法 | ELECTRON MICROSCOPY (4.5 Å) | 主引用文献 | Cryo-EM structures of human RAD51 recombinase filaments during catalysis of DNA-strand exchange Nat. Struct. Mol. Biol., 24, 2017
|
|
7RSP
| Structure of the VPS34 kinase domain with compound 14 | 分子名称: | (7R,8R)-2-[(3R)-3-methylmorpholin-4-yl]-7-(propan-2-yl)-6,7-dihydropyrazolo[1,5-a]pyrazin-4(5H)-one, GLYCEROL, Phosphatidylinositol 3-kinase catalytic subunit type 3 | 著者 | Hu, D.X, Patel, S, Chen, H, Wang, S, Staben, S, Dimitrova, Y.N, Wallweber, H.A, Lee, J.Y, Chan, G.K.Y, Sneeringer, C.J, Prangley, M.S, Moffat, J.G, Wu, C, Schutt, L.K, Salphati, L, Pang, J, McNamara, E, Huang, H, Chen, Y, Wang, Y, Zhao, W, Lim, J, Murthy, A, Siu, M. | 登録日 | 2021-08-11 | 公開日 | 2021-11-24 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.67 Å) | 主引用文献 | Structure-Based Design of Potent, Selective, and Orally Bioavailable VPS34 Kinase Inhibitors. J.Med.Chem., 65, 2022
|
|
7RSV
| Structure of the VPS34 kinase domain with compound 5 | 分子名称: | (5aS,8aR,9S)-2-[(3R)-3-methylmorpholin-4-yl]-5,5a,6,7,8,8a-hexahydro-4H-cyclopenta[e]pyrazolo[1,5-a]pyrazin-4-one, GLYCEROL, Phosphatidylinositol 3-kinase catalytic subunit type 3, ... | 著者 | Hu, D.X, Patel, S, Chen, H, Wang, S, Staben, S, Dimitrova, Y.N, Wallweber, H.A, Lee, J.Y, Chan, G.K.Y, Sneeringer, C.J, Prangley, M.S, Moffat, J.G, Wu, C, Schutt, L.K, Salphati, L, Pang, J, McNamara, E, Huang, H, Chen, Y, Wang, Y, Zhao, W, Lim, J, Murthy, A, Siu, M. | 登録日 | 2021-08-11 | 公開日 | 2021-11-24 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.78 Å) | 主引用文献 | Structure-Based Design of Potent, Selective, and Orally Bioavailable VPS34 Kinase Inhibitors. J.Med.Chem., 65, 2022
|
|
7RSJ
| Structure of the VPS34 kinase domain with compound 14 | 分子名称: | 1,2-ETHANEDIOL, GLYCEROL, N-{4-[(7R,8R)-4-oxo-7-(propan-2-yl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrazin-2-yl]pyridin-2-yl}cyclopropanecarboxamide, ... | 著者 | Hu, D.X, Patel, S, Chen, H, Wang, S, Staben, S, Dimitrova, Y.N, Wallweber, H.A, Lee, J.Y, Chan, G.K.Y, Sneeringer, C.J, Prangley, M.S, Moffat, J.G, Wu, C, Schutt, L.K, Salphati, L, Pang, J, McNamara, E, Huang, H, Chen, Y, Wang, Y, Zhao, W, Lim, J, Murthy, A, Siu, M. | 登録日 | 2021-08-11 | 公開日 | 2021-11-24 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.881 Å) | 主引用文献 | Structure-Based Design of Potent, Selective, and Orally Bioavailable VPS34 Kinase Inhibitors. J.Med.Chem., 65, 2022
|
|
4EJS
| Structure of yeast elongator subcomplex Elp456 | 分子名称: | Elongator complex protein 4, Elongator complex protein 5, Elongator complex protein 6 | 著者 | Lin, Z, Zhao, W, Long, J, Shen, Y. | 登録日 | 2012-04-07 | 公開日 | 2012-05-02 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.606 Å) | 主引用文献 | Crystal structure of elongator subcomplex Elp4-6 J.Biol.Chem., 287, 2012
|
|
6PKM
| MicroED structure of proteinase K from an uncoated, single lamella at 2.17A resolution (#8) | 分子名称: | Proteinase K | 著者 | Martynowycz, M.W, Zhao, W, Hattne, J, Jensen, G.J, Gonen, T. | 登録日 | 2019-06-29 | 公開日 | 2019-09-04 | 最終更新日 | 2019-12-18 | 実験手法 | ELECTRON CRYSTALLOGRAPHY (2.17 Å) | 主引用文献 | Qualitative Analyses of Polishing and Precoating FIB Milled Crystals for MicroED. Structure, 27, 2019
|
|
6PKQ
| MicroED structure of proteinase K from a platinum-coated, polished, single lamella at 1.85A resolution (#11) | 分子名称: | Proteinase K | 著者 | Martynowycz, M.W, Zhao, W, Hattne, J, Jensen, G.J, Gonen, T. | 登録日 | 2019-06-29 | 公開日 | 2019-09-04 | 最終更新日 | 2019-12-18 | 実験手法 | ELECTRON CRYSTALLOGRAPHY (1.85 Å) | 主引用文献 | Qualitative Analyses of Polishing and Precoating FIB Milled Crystals for MicroED. Structure, 27, 2019
|
|
6PKS
| MicroED structure of proteinase K from low-dose merged lamellae that were not pre-coated with platinum 2.16A resolution (LD) | 分子名称: | Proteinase K | 著者 | Martynowycz, M.W, Zhao, W, Hattne, J, Jensen, G.J, Gonen, T. | 登録日 | 2019-06-29 | 公開日 | 2019-09-04 | 最終更新日 | 2019-12-18 | 実験手法 | ELECTRON CRYSTALLOGRAPHY (2.16 Å) | 主引用文献 | Qualitative Analyses of Polishing and Precoating FIB Milled Crystals for MicroED. Structure, 27, 2019
|
|
6PKL
| MicroED structure of proteinase K from an uncoated, single lamella at 2.59A resolution (#7) | 分子名称: | Proteinase K | 著者 | Martynowycz, M.W, Zhao, W, Hattne, J, Jensen, G.J, Gonen, T. | 登録日 | 2019-06-29 | 公開日 | 2019-09-04 | 最終更新日 | 2019-12-18 | 実験手法 | ELECTRON CRYSTALLOGRAPHY (2.59 Å) | 主引用文献 | Qualitative Analyses of Polishing and Precoating FIB Milled Crystals for MicroED. Structure, 27, 2019
|
|
6PKT
| MicroED structure of proteinase K from merging low-dose, platinum pre-coated lamellae at 1.85A resolution (LDPT) | 分子名称: | Proteinase K | 著者 | Martynowycz, M.W, Zhao, W, Hattne, J, Jensen, G.J, Gonen, T. | 登録日 | 2019-06-29 | 公開日 | 2019-09-04 | 最終更新日 | 2019-12-18 | 実験手法 | ELECTRON CRYSTALLOGRAPHY (1.85 Å) | 主引用文献 | Qualitative Analyses of Polishing and Precoating FIB Milled Crystals for MicroED. Structure, 27, 2019
|
|
6PKJ
| MicroED structure of proteinase K from an uncoated, single lamella at 2.17A resolution (#2) | 分子名称: | Proteinase K | 著者 | Martynowycz, M.W, Zhao, W, Hattne, J, Jensen, G.J, Gonen, T. | 登録日 | 2019-06-29 | 公開日 | 2019-09-04 | 最終更新日 | 2019-12-18 | 実験手法 | ELECTRON CRYSTALLOGRAPHY (2.176 Å) | 主引用文献 | Qualitative Analyses of Polishing and Precoating FIB Milled Crystals for MicroED. Structure, 27, 2019
|
|
6PKO
| MicroED structure of proteinase K from a platinum coated, unpolished, single lamella at 2.07A resolution (#12) | 分子名称: | Proteinase K | 著者 | Martynowycz, M.W, Zhao, W, Hattne, J, Jensen, G.J, Gonen, T. | 登録日 | 2019-06-29 | 公開日 | 2019-09-04 | 最終更新日 | 2019-12-18 | 実験手法 | ELECTRON CRYSTALLOGRAPHY (2.07 Å) | 主引用文献 | Qualitative Analyses of Polishing and Precoating FIB Milled Crystals for MicroED. Structure, 27, 2019
|
|
6PKN
| MicroED structure of proteinase K from an unpolished, platinum-coated, single lamella at 2.08A resolution (#9) | 分子名称: | Proteinase K | 著者 | Martynowycz, M.W, Zhao, W, Hattne, J, Jensen, G.J, Gonen, T. | 登録日 | 2019-06-29 | 公開日 | 2019-09-04 | 最終更新日 | 2019-12-18 | 実験手法 | ELECTRON CRYSTALLOGRAPHY (2.08 Å) | 主引用文献 | Qualitative Analyses of Polishing and Precoating FIB Milled Crystals for MicroED. Structure, 27, 2019
|
|
6PKK
| MicroED structure of proteinase K from an uncoated, single lamella at 2.18A resolution (#5) | 分子名称: | Proteinase K | 著者 | Martynowycz, M.W, Zhao, W, Hattne, J, Jensen, G.J, Gonen, T. | 登録日 | 2019-06-29 | 公開日 | 2019-09-04 | 最終更新日 | 2019-12-18 | 実験手法 | ELECTRON CRYSTALLOGRAPHY (2.176 Å) | 主引用文献 | Qualitative Analyses of Polishing and Precoating FIB Milled Crystals for MicroED. Structure, 27, 2019
|
|
6PKP
| MicroED structure of proteinase K from a platinum-coated, polished, single lamella at 1.91A resolution (#10) | 分子名称: | Proteinase K | 著者 | Martynowycz, M.W, Zhao, W, Hattne, J, Jensen, G.J, Gonen, T. | 登録日 | 2019-06-29 | 公開日 | 2019-09-04 | 最終更新日 | 2019-12-18 | 実験手法 | ELECTRON CRYSTALLOGRAPHY (1.91 Å) | 主引用文献 | Qualitative Analyses of Polishing and Precoating FIB Milled Crystals for MicroED. Structure, 27, 2019
|
|
6PKR
| MicroED structure of proteinase K from a platinum-coated, polished, single lamella at 1.79A resolution (#13) | 分子名称: | Proteinase K | 著者 | Martynowycz, M.W, Zhao, W, Hattne, J, Jensen, G.J, Gonen, T. | 登録日 | 2019-06-29 | 公開日 | 2019-09-04 | 最終更新日 | 2019-12-18 | 実験手法 | ELECTRON CRYSTALLOGRAPHY (1.79 Å) | 主引用文献 | Qualitative Analyses of Polishing and Precoating FIB Milled Crystals for MicroED. Structure, 27, 2019
|
|
1YOP
| The solution structure of Kti11p | 分子名称: | Kti11p, ZINC ION | 著者 | Sun, J, Zhang, J, Wu, F, Xu, C, Li, S, Zhao, W, Wu, Z, Wu, J, Zhou, C.-Z, Shi, Y. | 登録日 | 2005-01-28 | 公開日 | 2005-04-05 | 最終更新日 | 2022-03-02 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure of Kti11p from Saccharomyces cerevisiae reveals a novel zinc-binding module. Biochemistry, 44, 2005
|
|
6U5G
| MicroED structure of a FIB-milled CypA Crystal | 分子名称: | Peptidyl-prolyl cis-trans isomerase A | 著者 | Wolff, A.M, Martynowycz, M.W, Zhao, W, Gonen, T, Fraser, J.S, Thompson, M.C. | 登録日 | 2019-08-27 | 公開日 | 2020-01-29 | 最終更新日 | 2023-10-11 | 実験手法 | ELECTRON CRYSTALLOGRAPHY (2.5 Å) | 主引用文献 | Comparing serial X-ray crystallography and microcrystal electron diffraction (MicroED) as methods for routine structure determination from small macromolecular crystals Iucrj, 7, 2020
|
|
3S69
| Crystal structure of saxthrombin | 分子名称: | CALCIUM ION, Thrombin-like enzyme defibrase | 著者 | Huang, K, Zhao, W, Teng, M, Niu, L. | 登録日 | 2011-05-25 | 公開日 | 2012-05-23 | 実験手法 | X-RAY DIFFRACTION (1.43 Å) | 主引用文献 | Structure of saxthrombin, a thrombin-like enzyme from Gloydius saxatilis. Acta Crystallogr.,Sect.F, 67, 2011
|
|