2EDV
 
 | | Solution structure of the PDZ domain from human FERM and PDZ domain containing 1 | | 分子名称: | FERM and PDZ domain-containing protein 1 | | 著者 | Seimiya, K, Kurosaki, C, Yoshida, M, Hayashi, F, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2007-02-15 | | 公開日 | 2007-08-21 | | 最終更新日 | 2024-05-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of the PDZ domain from human FERM and PDZ domain containing 1
to be published
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2EL4
 | | Solution structure of the 15th zf-C2H2 domain from human Zinc finger protein 268 | | 分子名称: | ZINC ION, Zinc finger protein 268 | | 著者 | Kurosaki, C, Nagashima, T, Yoshida, M, Hayashi, F, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2007-03-26 | | 公開日 | 2007-10-02 | | 最終更新日 | 2024-05-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of the 15th zf-C2H2 domain from human Zinc finger protein 268
To be Published
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2ELY
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2EDW
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2EDJ
 | | Solution structure of the fifth ig-like domain from human Roundabout homolog 2 | | 分子名称: | Roundabout homolog 2 | | 著者 | Kurosaki, C, Izumi, K, Yoshida, M, Hayashi, F, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2007-02-14 | | 公開日 | 2007-08-14 | | 最終更新日 | 2022-03-09 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of the fifth ig-like domain from human Roundabout homolog 2
to be published
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2EDR
 | | Solution structure of the ig-like domain (3361-3449) of human obscurin | | 分子名称: | Obscurin | | 著者 | Kurosaki, C, Izumi, K, Yoshida, M, Hayashi, F, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2007-02-14 | | 公開日 | 2007-08-14 | | 最終更新日 | 2024-05-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of the ig-like domain (3361-3449) of human obscurin
To be Published
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2EDO
 | | Solution structure of the first ig-like domain from human CD48 antigen | | 分子名称: | CD48 antigen | | 著者 | Nagashima, K, Nagashima, T, Yoshida, M, Hayashi, F, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2007-02-14 | | 公開日 | 2007-08-14 | | 最終更新日 | 2024-05-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of the first ig-like domain from human CD48 antigen
To be Published
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2ENY
 | | Solution structure of the ig-like domain (2735-2825) of human obscurin | | 分子名称: | Obscurin | | 著者 | Nagashima, K, Izumi, K, Yoshida, M, Hayashi, F, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2007-03-28 | | 公開日 | 2007-10-02 | | 最終更新日 | 2024-05-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of the ig-like domain (2735-2825) of human obscurin
To be Published
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2ENQ
 | | Solution structure of the C2 domain from human PI3-kinase p110 subunit alpha | | 分子名称: | Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha isoform | | 著者 | Endo, H, Nagashima, T, Yoshida, M, Hayashi, F, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2007-03-28 | | 公開日 | 2008-04-01 | | 最終更新日 | 2024-05-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of the C2 domain from human PI3-kinase p110 subunit alpha
To be Published
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2ENO
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2EO9
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2EOB
 | | Solution structure of the second SH2 domain from rat PLC gamma-2 | | 分子名称: | 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 2 | | 著者 | Sano, R, Hayashi, F, Nagashima, T, Yoshida, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2007-03-29 | | 公開日 | 2008-04-01 | | 最終更新日 | 2024-05-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of the second SH2 domain from rat PLC gamma-2
To be Published
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2EO6
 | | Solution structure of the SH2 domain from mouse B-cell linker protein BLNK | | 分子名称: | B-cell linker protein | | 著者 | Sano, R, Hayashi, F, Kurosaki, C, Yoshida, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2007-03-29 | | 公開日 | 2008-04-01 | | 最終更新日 | 2024-05-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of the SH2 domain from mouse B-cell linker protein BLNK
To be Published
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2EPA
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2EQZ
 | | Solution structure of the first HMG-box domain from high mobility group protein B3 | | 分子名称: | High mobility group protein B3 | | 著者 | Qin, X.R, Kurosaki, C, Yoshida, M, Hayahsi, F, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2007-03-30 | | 公開日 | 2008-04-01 | | 最終更新日 | 2024-05-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of the first HMG-box domain from high mobility group protein B3
To be Published
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5ZQR
 | | Tankyrase-2 in complex with compound 40c | | 分子名称: | 2-[4,6-difluoro-1-(2-hydroxyethyl)-1,2-dihydro-1'H-spiro[indole-3,4'-piperidin]-1'-yl]-5,6,7,8-tetrahydroquinazolin-4(3H)-one, GLYCEROL, PHOSPHATE ION, ... | | 著者 | Niwa, H, Shirai, F, Sato, S, Yoshimoto, N, Tsumura, T, Okue, M, Shirouzu, M, Seimiya, H, Umehara, T. | | 登録日 | 2018-04-19 | | 公開日 | 2019-04-03 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Discovery of Novel Spiroindoline Derivatives as Selective Tankyrase Inhibitors.
J. Med. Chem., 62, 2019
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6A84
 | | Tankyrase-2 in complex with compound 15d | | 分子名称: | 2-(4-chloro-1,2-dihydro-1'H-spiro[indole-3,4'-piperidin]-1'-yl)-5,6,7,8-tetrahydroquinazolin-4(3H)-one, GLYCEROL, PHOSPHATE ION, ... | | 著者 | Niwa, H, Shirai, F, Sato, S, Yoshimoto, N, Tsumura, T, Okue, M, Shirouzu, M, Seimiya, H, Umehara, T. | | 登録日 | 2018-07-06 | | 公開日 | 2019-04-03 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.98 Å) | | 主引用文献 | Discovery of Novel Spiroindoline Derivatives as Selective Tankyrase Inhibitors.
J. Med. Chem., 62, 2019
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6OVA
 | | Crystal Structure of TYK2 with novel pyrrolidinone inhibitor | | 分子名称: | 6-({4-[(3S)-3-cyano-3-cyclopropyl-2-oxopyrrolidin-1-yl]pyridin-2-yl}amino)-N,N-dimethylpyridine-3-carboxamide, Non-receptor tyrosine-protein kinase TYK2 | | 著者 | Skene, R.J, Hoffman, I.D. | | 登録日 | 2019-05-07 | | 公開日 | 2020-02-12 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Efficient synthesis of tert-butyl 3-cyano-3-cyclopropyl-2-oxopyrrolidine-4-carboxylates: Highly functionalized 2-pyrrolidinone enabling access to novel macrocyclic Tyk2 inhibitors.
Bioorg.Med.Chem.Lett., 30, 2020
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7QWM
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7QVF
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7QVC
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7QWL
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7QWG
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7NCI
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7NCJ
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