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Crystal structure of S. pombe Dcp1 in complex with the decapping enhancer EDC
分子名称:	Uncharacterized protein C18G6.09c, mRNA-decapping enzyme subunit 1
著者	Wurm, J.P, Sprangers, R.
登録日	2016-05-03
公開日	2016-06-01
最終更新日	2024-02-07
実験手法	X-RAY DIFFRACTION (2.043 Å)
主引用文献	The S. pombe mRNA decapping complex recruits cofactors and an Edc1-like activator through a single dynamic surface. Rna, 22, 2016

7PMM

DEAD-box helicase DbpA in the active conformation bound to a ss/dsRNA junction and ADP/BeF3
分子名称:	ADENOSINE-5'-DIPHOSPHATE, ATP-dependent RNA helicase DbpA, BERYLLIUM TRIFLUORIDE ION, ...
著者	Wurm, J.P.
登録日	2021-09-02
公開日	2022-09-14
最終更新日	2023-09-20
実験手法	X-RAY DIFFRACTION (3 Å)
主引用文献	Structural basis for RNA-duplex unwinding by the DEAD-box helicase DbpA. Rna, 29, 2023

7PMQ

DEAD-box helicase DbpA in the active conformation bound to a hairpin loop RNA and ADP/BeF3
分子名称:	ADENOSINE-5'-DIPHOSPHATE, ATP-dependent RNA helicase DbpA, BERYLLIUM TRIFLUORIDE ION, ...
著者	Wurm, J.P.
登録日	2021-09-02
公開日	2022-09-14
最終更新日	2024-01-31
実験手法	X-RAY DIFFRACTION (3.22 Å)
主引用文献	Structural basis for RNA-duplex unwinding by the DEAD-box helicase DbpA. Rna, 29, 2023

7BBB

Solution structure of C-terminal RecA and RRM domains of the DEAD box helicase DbpA
分子名称:	ATP-dependent RNA helicase DbpA
著者	Wurm, J.P, Sprangers, R.
登録日	2020-12-17
公開日	2021-07-14
最終更新日	2023-06-14
実験手法	SOLUTION NMR
主引用文献	Structural basis for the activation of the DEAD-box RNA helicase DbpA by the nascent ribosome. Proc.Natl.Acad.Sci.USA, 118, 2021

7PLI

DEAD-box helicase DbpA bound to single stranded RNA and ADP/BeF3
分子名称:	ADENOSINE-5'-DIPHOSPHATE, ATP-dependent RNA helicase DbpA, BERYLLIUM TRIFLUORIDE ION, ...
著者	Wurm, J.P.
登録日	2021-08-31
公開日	2022-09-07
最終更新日	2024-01-31
実験手法	X-RAY DIFFRACTION (2.5 Å)
主引用文献	Structural basis for RNA-duplex unwinding by the DEAD-box helicase DbpA. Rna, 29, 2023

5APG

Structure of the SAM-dependent rRNA:acp-transferase Tsr3 from Vulcanisaeta distributa
分子名称:	2-(N-MORPHOLINO)-ETHANESULFONIC ACID, TSR3, [(3S)-3-amino-4-hydroxy-4-oxo-butyl]-[[(2S,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxy-oxolan-2-yl]methyl]-methyl-selanium
著者	Wurm, J.P, Immer, C, Pogoryelov, D, Meyer, B, Koetter, P, Entian, K.-D, Woehnert, J.
登録日	2015-09-15
公開日	2016-04-27
最終更新日	2016-06-01
実験手法	X-RAY DIFFRACTION (1.6 Å)
主引用文献	Ribosome Biogenesis Factor Tsr3 is the Aminocarboxypropyl Transferase Responsible for 18S Rrna Hypermodification in Yeast and Humans Nucleic Acids Res., 44, 2016

5AP8

Structure of the SAM-dependent rRNA:acp-transferase Tsr3 from S. solfataricus
分子名称:	TSR3
著者	Wurm, J.P, Immer, C, Pogoryelov, D, Meyer, B, Koetter, P, Entian, K.-D, Woehnert, J.
登録日	2015-09-14
公開日	2016-04-27
最終更新日	2016-06-01
実験手法	X-RAY DIFFRACTION (2.246 Å)
主引用文献	Ribosome Biogenesis Factor Tsr3 is the Aminocarboxypropyl Transferase Responsible for 18S Rrna Hypermodification in Yeast and Humans Nucleic Acids Res., 44, 2016

2LCQ

Solution structure of the endonuclease Nob1 from P.horikoshii
分子名称:	Putative toxin VapC6, ZINC ION
著者	Veith, T, Martin, R, Wurm, J.P, Weis, B, Duchardt-Ferner, E, Safferthal, C, Hennig, R, Mirus, O, Bohnsack, M.T, Woehnert, J, Schleiff, E.
登録日	2011-05-05
公開日	2011-12-14
最終更新日	2012-05-09
実験手法	SOLUTION NMR
主引用文献	Structural and functional analysis of the archaeal endonuclease Nob1. Nucleic Acids Res., 40, 2012

7PVM

NMR structure of the C. thermophilum Xrn2 zinc finger
分子名称:	5'-3' exoribonuclease, ZINC ION
著者	Overbeck, J.H, Sprangers, R, Wurm, J.P.
登録日	2021-10-05
公開日	2022-07-06
最終更新日	2023-06-14
実験手法	SOLUTION NMR
主引用文献	Observation of conformational changes that underlie the catalytic cycle of Xrn2. Nat.Chem.Biol., 18, 2022

7AC8

Molecular basis for the unique allosteric activation mechanism of the heterodimeric imidazole glycerol phosphate synthase complex.
分子名称:	GLUTAMINE, Imidazole glycerol phosphate synthase subunit HisF, Imidazole glycerol phosphate synthase subunit HisH, ...
著者	Sung, S, Wilmanns, M.
登録日	2020-09-10
公開日	2021-05-19
最終更新日	2024-01-31
実験手法	X-RAY DIFFRACTION (2.06 Å)
主引用文献	Molecular basis for the allosteric activation mechanism of the heterodimeric imidazole glycerol phosphate synthase complex. Nat Commun, 12, 2021

5N2V

Changes in conformational equilibria regulate the activity of the Dcp2 decapping enzyme
分子名称:	7N-METHYL-8-HYDROGUANOSINE-5'-DIPHOSPHATE, Edc1, MAGNESIUM ION, ...
著者	Holdermann, I, Sprangers, R.
登録日	2017-02-08
公開日	2017-05-24
最終更新日	2024-02-28
実験手法	X-RAY DIFFRACTION (3.1 Å)
主引用文献	Changes in conformational equilibria regulate the activity of the Dcp2 decapping enzyme. Proc. Natl. Acad. Sci. U.S.A., 114, 2017

4QVK

Apo-crystal structure of Podospora anserina methyltransferase PaMTH1
分子名称:	1,2-ETHANEDIOL, PaMTH1 Methyltransferase
著者	Kudlinzki, D, Linhard, V.L, Chatterjee, D, Saxena, K, Sreeramulu, S, Schwalbe, H.
登録日	2014-07-15
公開日	2015-05-27
最終更新日	2024-02-28
実験手法	X-RAY DIFFRACTION (1.97 Å)
主引用文献	Structure and Biophysical Characterization of the S-Adenosylmethionine-dependent O-Methyltransferase PaMTH1, a Putative Enzyme Accumulating during Senescence of Podospora anserina. J.Biol.Chem., 290, 2015

6TRQ

S.c. Scavenger Decapping Enzyme DcpS in complex with the capped RNA dinucleotide m7G-GU
分子名称:	7N-METHYL-8-HYDROGUANOSINE-5'-DIPHOSPHATE, L-GUANOSINE-5'-MONOPHOSPHATE, PHOSPHONATE, ...
著者	Fuchs, A.-L, Neu, A, Sprangers, R.
登録日	2019-12-19
公開日	2020-07-22
最終更新日	2024-03-06
実験手法	X-RAY DIFFRACTION (2.944 Å)
主引用文献	Molecular basis of the selective processing of short mRNA substrates by the DcpS mRNA decapping enzyme. Proc.Natl.Acad.Sci.USA, 117, 2020

7OPK

Crystal structure of C. thermophilum Xrn2
分子名称:	5'-3' exoribonuclease, MAGNESIUM ION
著者	Overbeck, J.H, Sprangers, R.
登録日	2021-06-01
公開日	2022-07-06
最終更新日	2024-01-31
実験手法	X-RAY DIFFRACTION (3 Å)
主引用文献	Observation of conformational changes that underlie the catalytic cycle of Xrn2. Nat.Chem.Biol., 18, 2022

2N0J

Solution NMR Structure of the 27 nucleotide engineered neomycin sensing riboswitch RNA-ribostamycin complex
分子名称:	RIBOSTAMYCIN, RNA_(27-MER)
著者	Duchardt-Ferner, E, Gottstein-Schmidtke, S.R, Weigand, J.E, Ohlenschlaeger, O.E, Wurm, J, Hammann, C, Suess, B, Woehnert, J.
登録日	2015-03-09
公開日	2016-02-03
実験手法	SOLUTION NMR
主引用文献	What a Difference an OH Makes: Conformational Dynamics as the Basis for the Ligand Specificity of the Neomycin-Sensing Riboswitch. Angew.Chem.Int.Ed.Engl., 55, 2016

6HAG

The structure of the SAM/SAH-binding riboswitch.
分子名称:	S-ADENOSYL-L-HOMOCYSTEINE, SAM Riboswitch
著者	Weickhmann, A.K.
登録日	2018-08-07
公開日	2019-01-09
最終更新日	2020-01-29
実験手法	SOLUTION NMR
主引用文献	The structure of the SAM/SAH-binding riboswitch. Nucleic Acids Res., 47, 2019

6HTJ

Crystal structure of the translation recovery factor Trf from Sulfolobus solfataricus
分子名称:	Nucleic-acid-binding protein containing a Zn-ribbon, ZINC ION
著者	Woehnert, J, Pogoryelov, D, Kaiser, M.
登録日	2018-10-04
公開日	2019-10-16
最終更新日	2019-12-18
実験手法	X-RAY DIFFRACTION (1.65 Å)
主引用文献	Crystal structure of the translation recovery factor Trf from Sulfolobus solfataricus. Febs Open Bio, 2019

4YMG

Crystal structure of SAM-bound Podospora anserina methyltransferase PaMTH1
分子名称:	MAGNESIUM ION, PHOSPHATE ION, Putative SAM-dependent O-methyltranferase, ...
著者	Kudlinzki, D, Linhard, V.L, Chatterjee, D, Saxena, K, Sreeramulu, S, Schwalbe, H.
登録日	2015-03-06
公開日	2015-05-27
最終更新日	2024-01-10
実験手法	X-RAY DIFFRACTION (1.899 Å)
主引用文献	Structure and Biophysical Characterization of the S-Adenosylmethionine-dependent O-Methyltransferase PaMTH1, a Putative Enzyme Accumulating during Senescence of Podospora anserina. J.Biol.Chem., 290, 2015

4YMH

Crystal structure of SAH-bound Podospora anserina methyltransferase PaMTH1
分子名称:	DI(HYDROXYETHYL)ETHER, Putative SAM-dependent O-methyltranferase, S-ADENOSYL-L-HOMOCYSTEINE
著者	Kudlinzki, D, Linhard, V.L, Chatterjee, D, Saxena, K, Sreeramulu, S, Schwalbe, H.
登録日	2015-03-06
公開日	2015-05-27
最終更新日	2024-01-10
実験手法	X-RAY DIFFRACTION (1.876 Å)
主引用文献	Structure and Biophysical Characterization of the S-Adenosylmethionine-dependent O-Methyltransferase PaMTH1, a Putative Enzyme Accumulating during Senescence of Podospora anserina. J.Biol.Chem., 290, 2015

4I68

Crystal structure of the R444A / R449A double mutant of the HERA RNA helicase RRM domain
分子名称:	CHLORIDE ION, Heat resistant RNA dependent ATPase, ZINC ION
著者	Rudolph, M.G, Klostermeier, D.
登録日	2012-11-29
公開日	2013-04-24
最終更新日	2023-09-20
実験手法	X-RAY DIFFRACTION (1.63 Å)
主引用文献	Recognition of two distinct elements in the RNA substrate by the RNA-binding domain of the T. thermophilus DEAD box helicase Hera. Nucleic Acids Res., 41, 2013

4I67

Crystal structure of the RRM domain of RNA helicase HERA from T. thermophilus in complex with GGGC RNA
分子名称:	5'-R(PGPGPGP(RPC))-3', Heat resistant RNA dependent ATPase
著者	Rudolph, M.G, Klostermeier, D.
登録日	2012-11-29
公開日	2013-04-24
最終更新日	2023-09-20
実験手法	X-RAY DIFFRACTION (2.33 Å)
主引用文献	Recognition of two distinct elements in the RNA substrate by the RNA-binding domain of the T. thermophilus DEAD box helicase Hera. Nucleic Acids Res., 41, 2013

4I69

Crystal structure of the K463A mutant of the RRM domain of RNA helicase HERA from T. thermophilus
分子名称:	CHLORIDE ION, Heat resistant RNA dependent ATPase
著者	Rudolph, M.G, Klostermeier, D.
登録日	2012-11-29
公開日	2013-04-24
最終更新日	2023-09-20
実験手法	X-RAY DIFFRACTION (1.79 Å)
主引用文献	Recognition of two distinct elements in the RNA substrate by the RNA-binding domain of the T. thermophilus DEAD box helicase Hera. Nucleic Acids Res., 41, 2013

2MXS

Solution NMR-structure of the neomycin sensing riboswitch RNA bound to paromomycin
分子名称:	PAROMOMYCIN, RNA (27-MER)
著者	Schmidtke, S, Duchardt-Ferner, E, Ohlenschlaeger, O, Gottstein, D, Wohnert, J.
登録日	2015-01-14
公開日	2015-12-09
最終更新日	2016-02-03
実験手法	SOLUTION NMR
主引用文献	What a Difference an OH Makes: Conformational Dynamics as the Basis for the Ligand Specificity of the Neomycin-Sensing Riboswitch. Angew.Chem.Int.Ed.Engl., 55, 2016

6EWT

Solution Structure of Rhabdopeptide NRPS Docking Domain Kj12B-NDD
分子名称:	NRPS Kj12B-NDD
著者	Hacker, C, Cai, X, Kegler, C, Zhao, L, Weickhmann, A.K, Bode, H.B, Woehnert, J.
登録日	2017-11-06
公開日	2018-10-31
最終更新日	2023-06-14
実験手法	SOLUTION NMR
主引用文献	Structure-based redesign of docking domain interactions modulates the product spectrum of a rhabdopeptide-synthesizing NRPS. Nat Commun, 9, 2018

6EWV

Solution Structure of Docking Domain Complex of RXP NRPS: Kj12C NDD - Kj12B CDD
分子名称:	NRPS Kj12C-NDD, NRPS Kj12B-CDD
著者	Hacker, C, Cai, X, Kegler, C, Zhao, L, Weickhmann, A.K, Bode, H.B, Woehnert, J.
登録日	2017-11-06
公開日	2018-10-31
最終更新日	2023-06-14
実験手法	SOLUTION NMR
主引用文献	Structure-based redesign of docking domain interactions modulates the product spectrum of a rhabdopeptide-synthesizing NRPS. Nat Commun, 9, 2018

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