2MXS

Solution NMR-structure of the neomycin sensing riboswitch RNA bound to paromomycin

Summary for 2MXS

• Entry DOI: 10.2210/pdb2mxs/pdb
• Related: 2kxm
• NMR Information: BMRB: 25427
• Descriptor: RNA (27-MER), PAROMOMYCIN (2 entities in total)
• Functional Keywords: rna, riboswitch, aminoglycoside
• Total number of polymer chains: 1
• Total formula weight: 9172.66

Authors

Schmidtke, S.,Duchardt-Ferner, E.,Ohlenschlaeger, O.,Gottstein, D.,Wohnert, J. (deposition date: 2015-01-14, release date: 2015-12-09, Last modification date: 2016-02-03)

• Primary citation: Duchardt-Ferner, E.,Gottstein-Schmidtke, S.R.,Weigand, J.E.,Ohlenschlager, O.,Wurm, J.P.,Hammann, C.,Suess, B.,Wohnert, J.; What a Difference an OH Makes: Conformational Dynamics as the Basis for the Ligand Specificity of the Neomycin-Sensing Riboswitch.; Angew.Chem.Int.Ed.Engl., 55:1527-1530, 2016; PubMed: 26661511; DOI: 10.1002/anie.201507365

Experimental method

SOLUTION NMR