5APG

Structure of the SAM-dependent rRNA:acp-transferase Tsr3 from Vulcanisaeta distributa

Summary for 5APG

• Entry DOI: 10.2210/pdb5apg/pdb
• Related: 5AP8
• Descriptor: TSR3, [(3S)-3-amino-4-hydroxy-4-oxo-butyl]-[[(2S,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxy-oxolan-2-yl]methyl]-methyl-selanium, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ... (4 entities in total)
• Functional Keywords: transferase, s-adenosylmethionine, s-adenosylmethionine dependent 3-amino-3-carboxypropyl transferase, rrna, pseudouridine, sam, spout-fold
• Biological source: VULCANISAETA DISTRIBUTA
• Cellular location: Cytoplasm : E1QU22
• Total number of polymer chains: 3
• Total formula weight: 65353.85

Authors

Wurm, J.P.,Immer, C.,Pogoryelov, D.,Meyer, B.,Koetter, P.,Entian, K.-D.,Woehnert, J. (deposition date: 2015-09-15, release date: 2016-04-27, Last modification date: 2016-06-01)

• Primary citation: Entian, K.-D.,Immer, C.,Koetter, P.,Lafontaine, D.,Britter, M.,Pogoryelov, D.,Sharma, S.,Wohnert, J.,Wurm, J.P.; Ribosome Biogenesis Factor Tsr3 is the Aminocarboxypropyl Transferase Responsible for 18S Rrna Hypermodification in Yeast and Humans; Nucleic Acids Res., 44:4304-, 2016; PubMed: 27084949; DOI: 10.1093/NAR/GKW244

Experimental method

X-RAY DIFFRACTION (1.6 Å)