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4ZI2
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BU of 4zi2 by Molmil
BART-like domain of BARTL1/CCDC104 in complex with Arl3FL bound to GppNHp in P21 21 21
Descriptor: ADP-ribosylation factor-like protein 3, Cilia- and flagella-associated protein 36, MAGNESIUM ION, ...
Authors:Lokaj, M, Koerner, C, Koesling, S, Wittinghofer, A.
Deposit date:2015-04-27
Release date:2015-11-11
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The Interaction of CCDC104/BARTL1 with Arl3 and Implications for Ciliary Function.
Structure, 23, 2015
1YRG
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BU of 1yrg by Molmil
THE CRYSTAL STRUCTURE OF RNA1P: A NEW FOLD FOR A GTPASE-ACTIVATING PROTEIN
Descriptor: GTPASE-ACTIVATING PROTEIN RNA1_SCHPO
Authors:Hillig, R.C, Renault, L, Vetter, I.R, Drell, T, Wittinghofer, A, Becker, J.
Deposit date:1999-03-29
Release date:2000-03-29
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.66 Å)
Cite:The crystal structure of rna1p: a new fold for a GTPase-activating protein.
Mol.Cell, 3, 1999
1SRQ
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BU of 1srq by Molmil
Crystal Structure of the Rap1GAP catalytic domain
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, GTPase-activating protein 1, SULFATE ION
Authors:Daumke, O, Weyand, M, Chakrabarti, P.P, Vetter, I.R, Wittinghofer, A.
Deposit date:2004-03-23
Release date:2004-05-25
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:The GTPase activating protein Rap1GAP uses a catalytic asparagine
Nature, 429, 2004
5DE3
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BU of 5de3 by Molmil
The Crystal structure of Chlamydomonas reinhardtii Arl3 bound to GppNHp
Descriptor: ADP-ribosylation factor-like protein 3, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER
Authors:Gotthardt, K, Lokaj, M, Wittinghofer, A.
Deposit date:2015-08-25
Release date:2016-09-14
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.417 Å)
Cite:The Crystal structure of Chlamydomonas reinhardtii Arl3 bound to GppNHp
To Be Published
1Z2C
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BU of 1z2c by Molmil
Crystal structure of mDIA1 GBD-FH3 in complex with RhoC-GMPPNP
Descriptor: Diaphanous protein homolog 1, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ...
Authors:Rose, R, Weyand, M, Lammers, M, Ishizaki, T, Ahmadian, M.R, Wittinghofer, A.
Deposit date:2005-03-08
Release date:2005-05-10
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural and mechanistic insights into the interaction between Rho and mammalian Dia.
Nature, 435, 2005
5E8F
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BU of 5e8f by Molmil
Structure of Fully modified geranylgeranylated PDE6C Peptide in complex with PDE6D
Descriptor: Cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha', GERAN-8-YL GERAN, Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta
Authors:Fansa, E.K, O'Reilly, N.J, Ismail, S.A, Wittinghofer, A.
Deposit date:2015-10-14
Release date:2015-11-18
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The N- and C-terminal ends of RPGR can bind to PDE6 delta.
Embo Rep., 16, 2015
1XZP
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BU of 1xzp by Molmil
Structure of the GTP-binding protein TrmE from Thermotoga maritima
Descriptor: Probable tRNA modification GTPase trmE, SULFATE ION
Authors:Scrima, A, Vetter, I.R, Armengod, M.E, Wittinghofer, A.
Deposit date:2004-11-12
Release date:2005-01-04
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The structure of the TrmE GTP-binding protein and its implications for tRNA modification
Embo J., 24, 2005
1XZQ
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BU of 1xzq by Molmil
Structure of the GTP-binding protein TrmE from Thermotoga maritima complexed with 5-formyl-THF
Descriptor: N-{[4-({[(6R)-2-amino-5-formyl-4-oxo-1,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)phenyl]carbonyl}-L-glutamic acid, Probable tRNA modification GTPase trmE
Authors:Scrima, A, Vetter, I.R, Armengod, M.E, Wittinghofer, A.
Deposit date:2004-11-12
Release date:2005-01-04
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:The structure of the TrmE GTP-binding protein and its implications for tRNA modification
Embo J., 24, 2005
1FZQ
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BU of 1fzq by Molmil
CRYSTAL STRUCTURE OF MURINE ARL3-GDP
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 3, AMMONIUM ION, ...
Authors:Hillig, R.C, Hanzal-Bayer, M, Linari, M, Becker, J, Wittinghofer, A, Renault, L.
Deposit date:2000-10-04
Release date:2000-12-06
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural and biochemical properties show ARL3-GDP as a distinct GTP binding protein.
Structure Fold.Des., 8, 2000
1HE1
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BU of 1he1 by Molmil
Crystal structure of the complex between the GAP domain of the Pseudomonas aeruginosa ExoS toxin and human Rac
Descriptor: ALUMINUM FLUORIDE, EXOENZYME S, GUANOSINE-5'-DIPHOSPHATE, ...
Authors:Wurtele, M, Wolf, E, Pederson, K.J, Buchwald, G, Ahmadian, M.R, Barbieri, J.T, Wittinghofer, A.
Deposit date:2000-11-18
Release date:2001-01-02
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:How the Pseudomonas Aeruginosa Exos Toxin Downregulates Rac
Nat.Struct.Biol., 8, 2001
1HE9
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BU of 1he9 by Molmil
Crystal structure of the GAP domain of the Pseudomonas aeruginosa ExoS toxin
Descriptor: EXOENZYME S
Authors:Wurtele, M, Renault, L, Barbieri, J.T, Wittinghofer, A, Wolf, E.
Deposit date:2000-11-21
Release date:2001-03-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structure of the Exos Gtpase Activating Domain
FEBS Lett., 491, 2001
1IAQ
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BU of 1iaq by Molmil
C-H-RAS P21 PROTEIN MUTANT WITH THR 35 REPLACED BY SER (T35S) COMPLEXED WITH GUANOSINE-5'-[B,G-IMIDO] TRIPHOSPHATE
Descriptor: MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, TRANSFORMING PROTEIN P21/H-RAS-1
Authors:Spoerner, M, Herrmann, C, Vetter, I.R, Kalbitzer, H.R, Wittinghofer, A.
Deposit date:2001-03-23
Release date:2001-06-06
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Dynamic properties of the Ras switch I region and its importance for binding to effectors.
Proc.Natl.Acad.Sci.USA, 98, 2001
3T1Q
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BU of 3t1q by Molmil
MglA bound to GppNHp in complex with MglB
Descriptor: Gliding protein MglB, Gliding protein mglA, MAGNESIUM ION, ...
Authors:Miertzschke, M, Vetter, I.R, Koerner, C, Wittinghofer, A.
Deposit date:2011-07-22
Release date:2011-08-31
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural analysis of the Ras-like G protein MglA and its cognate GAP MglB and implications for bacterial polarity.
Embo J., 30, 2011
3T1T
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BU of 3t1t by Molmil
MglA bound to GDP in P1 tetrameric arrangement
Descriptor: GUANOSINE-5'-DIPHOSPHATE, Gliding protein mglA
Authors:Miertzschke, M, Vetter, I.R, Koerner, C, Wittinghofer, A.
Deposit date:2011-07-22
Release date:2011-08-31
Last modified:2011-11-02
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural analysis of the Ras-like G protein MglA and its cognate GAP MglB and implications for bacterial polarity.
Embo J., 30, 2011
3T1X
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BU of 3t1x by Molmil
MglB R124A E127A Monomer
Descriptor: Gliding protein MglB
Authors:Miertzschke, M, Vetter, I.R, Koerner, C, Wittinghofer, A.
Deposit date:2011-07-22
Release date:2011-08-31
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.91 Å)
Cite:Structural analysis of the Ras-like G protein MglA and its cognate GAP MglB and implications for bacterial polarity.
Embo J., 30, 2011
3T1S
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BU of 3t1s by Molmil
MglB Homodimer
Descriptor: Gliding protein MglB
Authors:Miertzschke, M, Vetter, I.R, Koerner, C, Wittinghofer, A.
Deposit date:2011-07-22
Release date:2011-08-31
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.67 Å)
Cite:Structural analysis of the Ras-like G protein MglA and its cognate GAP MglB and implications for bacterial polarity.
Embo J., 30, 2011
3T5D
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BU of 3t5d by Molmil
Crystal structure of Septin 7 in complex with GDP
Descriptor: GUANOSINE-5'-DIPHOSPHATE, Septin-7
Authors:Zent, E, Wittinghofer, A.
Deposit date:2011-07-27
Release date:2011-08-24
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Structural and biochemical properties of Sept7, a unique septin required for filament formation.
Biol.Chem., 392, 2011
1O9F
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BU of 1o9f by Molmil
Structural view of a fungal toxin acting on a 14-3-3 regulatory complex
Descriptor: 14-3-3-LIKE PROTEIN C, FUSICOCCIN, PLASMA MEMBRANE H+ ATPASE
Authors:Wurtele, M, Jelich-Ottmann, C, Wittinghofer, A, Oecking, C.
Deposit date:2002-12-12
Release date:2003-03-06
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural View of a Fungal Toxin Acting on a 14-3-3 Regulatory Complex
Embo J., 22, 2003
3T1O
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BU of 3t1o by Molmil
MglA bound to GDP
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, GUANOSINE-5'-DIPHOSPHATE, Gliding protein mglA, ...
Authors:Miertzschke, M, Vetter, I.R, Koerner, C, Wittinghofer, A.
Deposit date:2011-07-22
Release date:2011-08-31
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural analysis of the Ras-like G protein MglA and its cognate GAP MglB and implications for bacterial polarity.
Embo J., 30, 2011
3T1R
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BU of 3t1r by Molmil
MglB with tetrameric arrangement
Descriptor: Gliding protein MglB, MAGNESIUM ION
Authors:Miertzschke, M, Vetter, I.R, Koerner, C, Wittinghofer, A.
Deposit date:2011-07-22
Release date:2011-08-31
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural analysis of the Ras-like G protein MglA and its cognate GAP MglB and implications for bacterial polarity.
Embo J., 30, 2011
3T1V
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BU of 3t1v by Molmil
MglA bound to GDP in P2(1) tetrameric arrangement
Descriptor: GUANOSINE-5'-DIPHOSPHATE, Gliding protein mglA
Authors:Miertzschke, M, Vetter, I.R, Koerner, C, Wittinghofer, A.
Deposit date:2011-07-22
Release date:2011-08-31
Last modified:2011-11-02
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural analysis of the Ras-like G protein MglA and its cognate GAP MglB and implications for bacterial polarity.
Embo J., 30, 2011
3T12
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BU of 3t12 by Molmil
MglA in complex with MglB in transition state
Descriptor: GUANOSINE-5'-DIPHOSPHATE, Gliding protein MglB, Gliding protein mglA, ...
Authors:Miertzschke, M, Vetter, I.R, Koerner, C, Wittinghofer, A.
Deposit date:2011-07-21
Release date:2011-08-31
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural analysis of the Ras-like G protein MglA and its cognate GAP MglB and implications for bacterial polarity.
Embo J., 30, 2011
2BX6
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BU of 2bx6 by Molmil
Crystal Structure of the human Retinitis Pigmentosa protein 2 (RP2)
Descriptor: SULFATE ION, XRP2 PROTEIN
Authors:Kuhnel, K, Veltel, S, Schlichting, I, Wittinghofer, A.
Deposit date:2005-07-24
Release date:2006-01-18
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal Structure of the Human Retinitis Pigmentosa 2 Protein and its Interaction with Arl3
Structure, 14, 2006
3EG5
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BU of 3eg5 by Molmil
Crystal structure of MDIA1-TSH GBD-FH3 in complex with CDC42-GMPPNP
Descriptor: Cell division control protein 42 homolog, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ...
Authors:Lammers, M, Meyer, S, Kuehlmann, D, Wittinghofer, A.
Deposit date:2008-09-10
Release date:2008-10-14
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Specificity of Interactions between mDia Isoforms and Rho Proteins
J.Biol.Chem., 283, 2008
3E6Y
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BU of 3e6y by Molmil
Structure of 14-3-3 in complex with the differentiation-inducing agent Cotylenin A
Descriptor: 14-3-3-like protein C, CHLORIDE ION, Cotylenin A, ...
Authors:Ottmann, C, Weyand, M, Wittinghofer, A, Oecking, C.
Deposit date:2008-08-17
Release date:2009-03-10
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:A structural rationale for selective stabilization of anti-tumor interactions of 14-3-3 proteins by cotylenin A
J.Mol.Biol., 386, 2009

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