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3LCP
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BU of 3lcp by Molmil
Crystal structure of the carbohydrate recognition domain of LMAN1 in complex with MCFD2
Descriptor: CALCIUM ION, Multiple coagulation factor deficiency protein 2, Protein ERGIC-53
Authors:Wigren, E, Bourhis, J.M, Kursula, I, Guy, J.E, Lindqvist, Y.
Deposit date:2010-01-11
Release date:2010-01-26
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Crystal structure of the LMAN1-CRD/MCFD2 transport receptor complex provides insight into combined deficiency of factor V and factor VIII.
Febs Lett., 584, 2010
6Y6C
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BU of 6y6c by Molmil
TREM2 extracellular domain (19-174) in complex with single-chain variable fragment (scFv-4)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Single chain variable, Triggering receptor expressed on myeloid cells 2
Authors:Szykowska, A, Preger, C, Williams, E, Mukhopadhyay, S.M.M, McKinley, G, Gruslund, S, Wigren, E, Persson, H, Arrowsmith, C.H, Edwards, A, von Delft, F, Bountra, C, Davis, J.B, Di Daniel, E, Burgess-Brown, N, Bullock, A.
Deposit date:2020-02-26
Release date:2021-02-17
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.26 Å)
Cite:Selection and structural characterization of anti-TREM2 scFvs that reduce levels of shed ectodomain.
Structure, 29, 2021
6YMQ
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BU of 6ymq by Molmil
TREM2 extracellular domain (19-131) in complex with single-chain variable 4 (scFv-4)
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Single-chain variable 4, ...
Authors:Szykowska, A, Preger, C, Scacioc, A, Mukhopadhyay, S.M.M, McKinley, G, Graslund, S, Wigren, E, Persson, H, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Di Daniel, E, Davis, J.B, Burgess-Brown, N, Bullock, A.
Deposit date:2020-04-09
Release date:2021-02-17
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (3.07 Å)
Cite:Selection and structural characterization of anti-TREM2 scFvs that reduce levels of shed ectodomain.
Structure, 29, 2021
6YYE
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BU of 6yye by Molmil
TREM2 extracellular domain (19-131) in complex with single-chain variable fragment (scFv-2)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, TREM2 Single chain variable 2, Triggering receptor expressed on myeloid cells 2
Authors:Szykowska, A, Preger, C, Krojer, T, Mukhopadhyay, S.M.M, McKinley, G, Graslund, S, Wigren, E, Persson, H, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Di Daniel, E, Burgess-Brown, N, Bullock, A.
Deposit date:2020-05-04
Release date:2021-02-17
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (3.36 Å)
Cite:Selection and structural characterization of anti-TREM2 scFvs that reduce levels of shed ectodomain.
Structure, 29, 2021
6G8R
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BU of 6g8r by Molmil
SP140 PHD-Bromodomain complex with scFv
Descriptor: 1,2-ETHANEDIOL, Nuclear body protein SP140, ZINC ION, ...
Authors:Fairhead, M, Graslund, S, Strain-Damerell, C, Picaud, S.S, Pike, A.C.W, Pinkas, D.M, Wigren, E, Preger, C, Persson Lotsholm, H, Ossipova, E, Filippakopoulos, P, Burgess-Brown, N.A, Arrowsmith, C.H, Edwards, A.M, Bountra, C, von Delft, F, Structural Genomics Consortium (SGC)
Deposit date:2018-04-09
Release date:2018-04-18
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.74 Å)
Cite:SP140 PHD-Bromodomain complex with scFv
To Be Published
2VRG
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BU of 2vrg by Molmil
Structure of human MCFD2
Descriptor: CALCIUM ION, MULTIPLE COAGULATION FACTOR DEFICIENCY PROTEIN 2
Authors:Guy, J.E, Wigren, E, Svard, M, Hard, T, Lindqvist, Y.
Deposit date:2008-04-04
Release date:2008-07-15
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:New insights into multiple coagulation factor deficiency from the solution structure of human MCFD2.
J. Mol. Biol., 381, 2008
4GKY
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BU of 4gky by Molmil
Crystal structure of a carbohydrate-binding domain
Descriptor: CALCIUM ION, GLYCEROL, Protein ERGIC-53, ...
Authors:Page, R.C, Zheng, C, Nix, J.C, Misra, S, Zhang, B.
Deposit date:2012-08-13
Release date:2013-06-05
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.4201 Å)
Cite:Structural Characterization of Carbohydrate Binding by LMAN1 Protein Provides New Insight into the Endoplasmic Reticulum Export of Factors V (FV) and VIII (FVIII).
J.Biol.Chem., 288, 2013
4GKX
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BU of 4gkx by Molmil
Crystal structure of a carbohydrate-binding domain
Descriptor: CALCIUM ION, GLYCEROL, Protein ERGIC-53, ...
Authors:Page, R.C, Zheng, C, Nix, J.C, Misra, S, Zhang, B.
Deposit date:2012-08-13
Release date:2013-06-05
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural Characterization of Carbohydrate Binding by LMAN1 Protein Provides New Insight into the Endoplasmic Reticulum Export of Factors V (FV) and VIII (FVIII).
J.Biol.Chem., 288, 2013

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