1VTD
| UNUSUAL HELICAL PACKING IN CRYSTALS OF DNA BEARING A MUTATION HOT SPOT | Descriptor: | DNA (5'-D(*AP*CP*CP*GP*GP*CP*GP*CP*CP*AP*CP*A)-3'), DNA (5'-D(*TP*GP*TP*GP*GP*CP*GP*CP*CP*GP*GP*T)-3') | Authors: | Timsit, Y, Westhof, E, Fuchs, R.P.P, Moras, D. | Deposit date: | 1996-12-12 | Release date: | 2011-07-13 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Unusual helical packing in crystals of DNA bearing a mutation hot spot. Nature, 341, 1989
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1RMN
| A THREE-DIMENSIONAL MODEL FOR THE HAMMERHEAD RIBOZYME BASED ON FLUORESCENCE MEASUREMENTS | Descriptor: | RNA (49-MER) | Authors: | Tuschl, T, Gohlke, C, Jovin, T.M, Westhof, E, Eckstein, F. | Deposit date: | 1994-10-20 | Release date: | 1995-01-26 | Last modified: | 2024-02-14 | Method: | FLUORESCENCE TRANSFER | Cite: | A three-dimensional model for the hammerhead ribozyme based on fluorescence measurements. Science, 266, 1994
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4P20
| Crystal structures of the bacterial ribosomal decoding site complexed with amikacin | Descriptor: | (2S)-N-[(1R,2S,3S,4R,5S)-4-[(2R,3R,4S,5S,6R)-6-(aminomethyl)-3,4,5-tris(oxidanyl)oxan-2-yl]oxy-5-azanyl-2-[(2S,3R,4S,5S ,6R)-4-azanyl-6-(hydroxymethyl)-3,5-bis(oxidanyl)oxan-2-yl]oxy-3-oxidanyl-cyclohexyl]-4-azanyl-2-oxidanyl-butanamide, 5'-R(*UP*UP*GP*CP*GP*UP*CP*AP*CP*AP*CP*CP*GP*GP*UP*GP*AP*AP*GP*UP*CP*GP*C)-3' | Authors: | Kondo, J, Francois, B, Russell, R.J.M, Murray, J.B, Westhof, E. | Deposit date: | 2014-02-28 | Release date: | 2014-05-07 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Crystal structure of the bacterial ribosomal decoding site complexed with amikacin containing the gamma-amino-alpha-hydroxybutyryl (haba) group. Biochimie, 88, 2006
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4P9R
| Speciation of a group I intron into a lariat capping ribozyme (Heavy atom derivative) | Descriptor: | IRIDIUM HEXAMMINE ION, MAGNESIUM ION, RNA (189-MER) | Authors: | Meyer, M, Nielsen, H, Olieric, V, Roblin, P, Johansen, S.D, Westhof, E, Masquida, B. | Deposit date: | 2014-04-04 | Release date: | 2014-05-28 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.703 Å) | Cite: | Speciation of a group I intron into a lariat capping ribozyme. Proc.Natl.Acad.Sci.USA, 111, 2014
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4P8Z
| Speciation of a group I intron into a lariat capping ribozyme | Descriptor: | Didymium iridis partial IGS, 18S rRNA gene, I-DirI gene and partial ITS1 | Authors: | Meyer, M, Nielsen, H, Olieric, V, Roblin, P, Johansen, S.D, Westhof, E, Masquida, B. | Deposit date: | 2014-04-01 | Release date: | 2014-05-28 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (3.85 Å) | Cite: | Speciation of a group I intron into a lariat capping ribozyme. Proc.Natl.Acad.Sci.USA, 111, 2014
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4V8M
| High-resolution cryo-electron microscopy structure of the Trypanosoma brucei ribosome | Descriptor: | 18S RRNA OF THE SMALL RIBOSOMAL SUBUNIT, 40S RIBOSOMAL PROTEIN S10, PUTATIVE, ... | Authors: | Hashem, Y, des Georges, A, Fu, J, Buss, S.N, Jossinet, F, Jobe, A, Zhang, Q, Liao, H.Y, Grassucci, R.A, Bajaj, C, Westhof, E, Madison-Antenucci, S, Frank, J. | Deposit date: | 2012-12-09 | Release date: | 2014-07-09 | Last modified: | 2019-12-11 | Method: | ELECTRON MICROSCOPY (5.57 Å) | Cite: | High-Resolution Cryo-Electron Microscopy Structure of the Trypanosoma Brucei Ribosome. Nature, 494, 2013
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2BEE
| Complex Between Paromomycin derivative JS4 and the 16S-Rrna A Site | Descriptor: | (2S,3S,4R,5R,6R)-5-AMINO-2-(AMINOMETHYL)-6-((2R,3R,4R,5S)-4-(2-(3-AMINOPROPYLAMINO)ETHOXY)-5-((1R,2R,3S,5R,6S)-3,5-DIAM INO-2-((2S,3R,4R,5S,6R)-3-AMINO-4,5-DIHYDROXY-6-(HYDROXYMETHYL)-TETRAHYDRO-2H-PYRAN-2-YLOXY)-6-HYDROXYCYCLOHEXYLOXY)-2-( HYDROXYMETHYL)-TETRAHYDROFURAN-3-YLOXY)-TETRAHYDRO-2H-PYRAN-3,4-DIOL, 5'-R(*CP*GP*CP*GP*UP*CP*AP*CP*AP*CP*CP*GP*GP*UP*GP*AP*AP*GP*UP*CP*GP*C)-3' | Authors: | Francois, B, Westhof, E. | Deposit date: | 2005-10-24 | Release date: | 2005-12-20 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Antibacterial aminoglycosides with a modified mode of binding to the ribosomal-RNA decoding site ANGEW.CHEM.INT.ED.ENGL., 43, 2004
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5J02
| Structure of the lariat form of a chimeric derivative of the Oceanobacillus iheyensis group II intron in the presence of NH4+, MG2+ and an inactive 5' exon. | Descriptor: | 5' EXON ANALOG (5'-R(*CP*UP*GP*UP*UP*AP*(5MU))-3'), AMMONIUM ION, GROUP II INTRON LARIAT, ... | Authors: | Costa, M, Walbott, H, Monachello, D, Westhof, E, Michel, F. | Deposit date: | 2016-03-26 | Release date: | 2016-12-14 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (3.493 Å) | Cite: | Crystal structures of a group II intron lariat primed for reverse splicing. Science, 354, 2016
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2BE0
| Complex Between Paromomycin Derivative JS5-39 and the 16S-Rrna A-Site. | Descriptor: | (2S,3S,4R,5R,6R)-5-AMINO-2-(AMINOMETHYL)-6-((2R,3R,4R,5S)-5-((1R,2R,3S,5R,6S)-3,5-DIAMINO-2-((2S,3R,4R,5S,6R)-3-AMINO-4 ,5-DIHYDROXY-6-(HYDROXYMETHYL)-TETRAHYDRO-2H-PYRAN-2-YLOXY)-6-HYDROXYCYCLOHEXYLOXY)-2-(HYDROXYMETHYL)-4-(2-((R)-PIPERIDI N-3-YLMETHYLAMINO)ETHOXY)-TETRAHYDROFURAN-3-YLOXY)-TETRAHYDRO-2H-PYRAN-3,4-DIOL, 5'-R(*CP*GP*CP*GP*UP*CP*AP*CP*AP*CP*CP*GP*GP*UP*GP*AP*AP*GP*UP*CP*GP*C)-3' | Authors: | Francois, B, Westhof, E. | Deposit date: | 2005-10-21 | Release date: | 2005-12-20 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.63 Å) | Cite: | Antibacterial aminoglycosides with a modified mode of binding to the ribosomal-RNA decoding site ANGEW.CHEM.INT.ED.ENGL., 43, 2004
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5J01
| Structure of the lariat form of a chimeric derivative of the Oceanobacillus iheyensis group II intron in the presence of NH4+ and MG2+. | Descriptor: | AMMONIUM ION, MAGNESIUM ION, group II intron lariat | Authors: | Costa, M, Walbott, H, Monachello, D, Westhof, E, Michel, F. | Deposit date: | 2016-03-26 | Release date: | 2016-12-14 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (3.39 Å) | Cite: | Crystal structures of a group II intron lariat primed for reverse splicing. Science, 354, 2016
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1LC4
| Crystal Structure of Tobramycin Bound to the Eubacterial 16S rRNA A Site | Descriptor: | 5'-R(*UP*UP*GP*CP*GP*UP*CP*AP*CP*AP*CP*CP*GP*GP*UP*GP*AP*AP*GP*UP*CP*GP*C)-3', TOBRAMYCIN | Authors: | Vicens, Q, Westhof, E. | Deposit date: | 2002-04-05 | Release date: | 2003-04-08 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.54 Å) | Cite: | Crystal Structure of a Complex between the Aminoglycoside Tobramycin and an
Oligonucleotide Containing the Ribosomal Decoding A Site Chem.Biol., 9, 2002
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1KOD
| RNA APTAMER COMPLEXED WITH CITRULLINE, NMR | Descriptor: | CITRULLINE, RNA (5'-R(P*AP*CP*GP*GP*UP*UP*AP*GP*GP*UP*CP*GP*CP*U)-3'), RNA (5'-R(P*AP*GP*AP*AP*GP*GP*AP*GP*UP*GP*U)-3') | Authors: | Yang, Y.S, Kochoyan, M, Burgstaller, P, Westhof, E, Famulok, M. | Deposit date: | 1996-03-28 | Release date: | 1996-11-08 | Last modified: | 2023-11-15 | Method: | SOLUTION NMR | Cite: | Structural basis of ligand discrimination by two related RNA aptamers resolved by NMR spectroscopy. Science, 272, 1996
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1KOC
| RNA APTAMER COMPLEXED WITH ARGININE, NMR | Descriptor: | ARGININE, RNA (5'-R(P*AP*CP*AP*GP*GP*UP*AP*GP*GP*UP*CP*GP*CP*U)-3'), RNA (5'-R(P*AP*GP*AP*AP*GP*GP*AP*GP*CP*GP*U)-3') | Authors: | Yang, Y.S, Kochoyan, M, Burgstaller, P, Westhof, E, Famulok, M. | Deposit date: | 1996-03-28 | Release date: | 1996-08-17 | Last modified: | 2022-02-23 | Method: | SOLUTION NMR | Cite: | Structural basis of ligand discrimination by two related RNA aptamers resolved by NMR spectroscopy. Science, 272, 1996
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1DN5
| SOLVATION OF THE LEFT-HANDED HEXAMER D(5BRC-G-5BRC-G-5BRC-G) IN CRYSTALS GROWN AT TWO TEMPERATURES | Descriptor: | DNA (5'-D(*(CBR)P*GP*(CBR)P*GP*(CBR)P*G)-3') | Authors: | Chevrier, B, Dock, A.C, Hartmann, B, Leng, M, Moras, D, Thuong, M.T, Westhof, E. | Deposit date: | 1986-12-01 | Release date: | 1987-04-16 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Solvation of the left-handed hexamer d(5BrC-G-5BrC-G-5 BrC-G) in crystals grown at two temperatures. J.Mol.Biol., 188, 1986
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1DN4
| SOLVATION OF THE LEFT-HANDED HEXAMER D(5BRC-G-5BRC-G-5BRC-G) IN CRYSTALS GROWN AT TWO TEMPERATURES | Descriptor: | DNA (5'-D(*(CBR)P*GP*(CBR)P*GP*(CBR)P*G)-3') | Authors: | Chevrier, B, Dock, A.C, Hartmann, B, Leng, M, Moras, D, Thuong, M.T, Westhof, E. | Deposit date: | 1986-12-01 | Release date: | 1987-04-16 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Solvation of the left-handed hexamer d(5BrC-G-5BrC-G-5 BrC-G) in crystals grown at two temperatures. J.Mol.Biol., 188, 1986
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1DN8
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1FQZ
| NMR VALIDATED MODEL OF DOMAIN IIID OF HEPATITIS C VIRUS INTERNAL RIBOSOME ENTRY SITE | Descriptor: | HEPATITIS C VIRUS IRES DOMAIN IIID | Authors: | Klinck, R, Westhof, E, Walker, S, Afshar, M, Collier, A, Aboul-ela, F. | Deposit date: | 2000-09-07 | Release date: | 2001-01-17 | Last modified: | 2022-02-23 | Method: | SOLUTION NMR | Cite: | A potential RNA drug target in the hepatitis C virus internal ribosomal entry site. RNA, 6, 2000
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6GYV
| Lariat-capping ribozyme (circular permutation form) | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Lariat-capping ribozyme, MAGNESIUM ION, ... | Authors: | Masquida, B, Meyer, M, Nielsen, H, Olieric, V, Roblin, P, Johansen, S.D, Westhof, E. | Deposit date: | 2018-07-02 | Release date: | 2018-08-22 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.50003624 Å) | Cite: | Speciation of a group I intron into a lariat capping ribozyme. Proc. Natl. Acad. Sci. U.S.A., 111, 2014
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1J7T
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3BNP
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3BNT
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3BNL
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3BNQ
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2NOQ
| Structure of ribosome-bound cricket paralysis virus IRES RNA | Descriptor: | 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S5, ... | Authors: | Schuler, M, Connell, S.R, Lescoute, A, Giesebrecht, J, Dabrowski, M, Schroeer, B, Mielke, T, Penczek, P.A, Westhof, E, Spahn, C.M.T. | Deposit date: | 2006-10-26 | Release date: | 2006-11-21 | Last modified: | 2023-12-27 | Method: | ELECTRON MICROSCOPY (7.3 Å) | Cite: | Structure of the ribosome-bound cricket paralysis virus IRES RNA. Nat.Struct.Mol.Biol., 13, 2006
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3BNO
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