8HLP
 
 | | Cryo-EM structure of human high-voltage activated L-type calcium channel CaV1.2 (apo) | | 分子名称: | 1,2-Distearoyl-sn-glycerophosphoethanolamine, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | | 著者 | Wei, Y, Yu, Z, Zhao, Y. | | 登録日 | 2022-11-30 | | 公開日 | 2024-04-24 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Structural bases of inhibitory mechanism of Ca V 1.2 channel inhibitors.
Nat Commun, 15, 2024
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8HMA
 | | Cryo-EM structure of human high-voltage activated L-type calcium channel CaV1.2 in complex with tetrandrine (TET) | | 分子名称: | 1,2-Distearoyl-sn-glycerophosphoethanolamine, 2-acetamido-2-deoxy-beta-D-glucopyranose, 6,6',7,12-tetramethoxy-2,2'-dimethyl-1beta-3,4-didehydroberbaman, ... | | 著者 | Wei, Y, Yu, Z, Zhao, Y. | | 登録日 | 2022-12-02 | | 公開日 | 2024-04-24 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Structural bases of inhibitory mechanism of Ca V 1.2 channel inhibitors.
Nat Commun, 15, 2024
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8HMB
 | | Cryo-EM structure of human high-voltage activated L-type calcium channel CaV1.2 in complex with benidipine (BEN) | | 分子名称: | (3R)-1-benzylpiperidin-3-yl methyl (2R,3R,4R,5R,6S)-2,6-dimethyl-4-(3-nitrophenyl)piperidine-3,5-dicarboxylate, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Wei, Y, Yu, Z, Zhao, Y. | | 登録日 | 2022-12-02 | | 公開日 | 2024-04-24 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Structural bases of inhibitory mechanism of Ca V 1.2 channel inhibitors.
Nat Commun, 15, 2024
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8WFK
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8WFI
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8WFL
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8WFJ
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6E16
 | | Ternary structure of c-Myc-TBP-TAF1 | | 分子名称: | Transcription initiation factor TFIID subunit 1,Myc proto-oncogene protein,TATA-box-binding protein | | 著者 | Wei, Y, Dong, A, Sunnerhagen, M, Penn, L, Tong, Y, Edwards, A.M, Arrowsmith, C.H, Structural Genomics Consortium (SGC) | | 登録日 | 2018-07-09 | | 公開日 | 2019-10-02 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Multiple direct interactions of TBP with the MYC oncoprotein.
Nat.Struct.Mol.Biol., 26, 2019
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6E24
 | | Ternary structure of c-Myc-TBP-TAF1 | | 分子名称: | Transcription initiation factor TFIID subunit 1,Myc proto-oncogene protein,TATA-box-binding protein | | 著者 | Wei, Y, Dong, A, Sunnerhagen, M, Penn, L, Tong, Y, Edwards, A.M, Arrowsmith, C.H, Structural Genomics Consortium (SGC) | | 登録日 | 2018-07-10 | | 公開日 | 2019-10-02 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (3.001 Å) | | 主引用文献 | Multiple direct interactions of TBP with the MYC oncoprotein.
Nat.Struct.Mol.Biol., 26, 2019
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2PP4
 | | Solution Structure of ETO-TAFH refined in explicit solvent | | 分子名称: | Protein ETO | | 著者 | Wei, Y, Liu, S, Lausen, J, Woodrell, C, Cho, S, Biris, N, Kobayashi, N, Yokoyama, S, Werner, M.H. | | 登録日 | 2007-04-27 | | 公開日 | 2007-06-19 | | 最終更新日 | 2021-10-20 | | 実験手法 | SOLUTION NMR | | 主引用文献 | A TAF4-homology domain from the corepressor ETO is a docking platform for positive and negative regulators of transcription
Nat.Struct.Mol.Biol., 14, 2007
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1FTN
 | | CRYSTAL STRUCTURE OF THE HUMAN RHOA/GDP COMPLEX | | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, TRANSFORMING PROTEIN RHOA (H12) | | 著者 | Wei, Y, Zhang, Y, Derewenda, U, Liu, X, Minor, W, Nakamoto, R.K, Somlyo, A.V, Somlyo, A.P, Derewenda, Z.S. | | 登録日 | 1997-03-13 | | 公開日 | 1998-03-18 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Crystal structure of RhoA-GDP and its functional implications.
Nat.Struct.Biol., 4, 1997
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1ESC
 | | THE MOLECULAR MECHANISM OF ENANTIORECOGNITION BY ESTERASES | | 分子名称: | ESTERASE | | 著者 | Wei, Y, Schottel, J.L, Derewenda, U, Swenson, L, Patkar, S, Derewenda, Z.S. | | 登録日 | 1994-10-07 | | 公開日 | 1995-10-15 | | 最終更新日 | 2019-08-14 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | A novel variant of the catalytic triad in the Streptomyces scabies esterase.
Nat.Struct.Biol., 2, 1995
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6E7O
 | | Crystal structure of deglycosylated human EPDR1 | | 分子名称: | Mammalian ependymin-related protein 1 | | 著者 | Wei, Y, Prive, G.G. | | 登録日 | 2018-07-27 | | 公開日 | 2019-01-23 | | 最終更新日 | 2020-01-08 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Crystal structures of human lysosomal EPDR1 reveal homology with the superfamily of bacterial lipoprotein transporters.
Commun Biol, 2, 2019
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6E8N
 | | Crystal structure of glycosylated human EPDR1 | | 分子名称: | Mammalian ependymin-related protein 1, NONAETHYLENE GLYCOL | | 著者 | Wei, Y, Prive, G.G. | | 登録日 | 2018-07-30 | | 公開日 | 2019-01-23 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Crystal structures of human lysosomal EPDR1 reveal homology with the superfamily of bacterial lipoprotein transporters.
Commun Biol, 2, 2019
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1JKM
 | | BREFELDIN A ESTERASE, A BACTERIAL HOMOLOGUE OF HUMAN HORMONE SENSITIVE LIPASE | | 分子名称: | BREFELDIN A ESTERASE | | 著者 | Wei, Y, Contreras, A.J, Sheffield, P, Osterlund, T, Derewenda, U, Matern, U.O, Derewenda, Z.S. | | 登録日 | 1998-02-04 | | 公開日 | 1999-02-16 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Crystal structure of brefeldin A esterase, a bacterial homolog of the mammalian hormone-sensitive lipase.
Nat.Struct.Biol., 6, 1999
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1P68
 | | Solution structure of S-824, a de novo designed four helix bundle | | 分子名称: | De novo designed protein S-824 | | 著者 | Wei, Y, Kim, S, Fela, D, Baum, J, Hecht, M.H. | | 登録日 | 2003-04-29 | | 公開日 | 2003-11-11 | | 最終更新日 | 2022-02-23 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of a de novo protein from a designed combinatorial library.
Proc.Natl.Acad.Sci.Usa, 100, 2003
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1ESE
 | | THE MOLECULAR MECHANISM OF ENANTIORECOGNITION BY ESTERASES | | 分子名称: | DIETHYL PHOSPHONATE, ESTERASE | | 著者 | Wei, Y, Schottel, J.L, Derewenda, U, Swenson, L, Patkar, S, Derewenda, Z.S. | | 登録日 | 1994-10-07 | | 公開日 | 1995-10-15 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | A novel variant of the catalytic triad in the Streptomyces scabies esterase.
Nat.Struct.Biol., 2, 1995
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1ESD
 | | THE MOLECULAR MECHANISM OF ENANTIORECOGNITION BY ESTERASES | | 分子名称: | ESTERASE, METHYLPHOSPHONIC ACID ESTER GROUP | | 著者 | Wei, Y, Schottel, J.L, Derewenda, U, Swenson, L, Patkar, S, Derewenda, Z.S. | | 登録日 | 1994-10-07 | | 公開日 | 1995-10-15 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | A novel variant of the catalytic triad in the Streptomyces scabies esterase.
Nat.Struct.Biol., 2, 1995
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1F1J
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4I8O
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3FV5
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2QV1
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5I8J
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1JFR
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7LQT
 | | Solution NMR structure of the PNUTS amino-terminal Domain fused to Myc Homology Box 0 | | 分子名称: | Serine/threonine-protein phosphatase 1 regulatory subunit 10,Myc proto-oncogene protein fusion | | 著者 | Lemak, A, Wei, Y, Duan, S, Houliston, S, Penn, L.Z, Arrowsmith, C.H. | | 登録日 | 2021-02-15 | | 公開日 | 2021-03-03 | | 最終更新日 | 2023-06-14 | | 実験手法 | SOLUTION NMR | | 主引用文献 | The MYC oncoprotein directly interacts with its chromatin cofactor PNUTS to recruit PP1 phosphatase.
Nucleic Acids Res., 50, 2022
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