4G6F
 
 | | Crystal Structure of 10E8 Fab in Complex with an HIV-1 gp41 Peptide | | 分子名称: | 10E8 Heavy Chain, 10E8 Light Chain, gp41 MPER Peptide | | 著者 | Ofek, G, Huang, J, Connors, M, Kwong, P.D. | | 登録日 | 2012-07-19 | | 公開日 | 2012-09-26 | | 最終更新日 | 2017-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Broad and potent neutralization of HIV-1 by a gp41-specific human antibody.
Nature, 491, 2012
|
|
8FVS
 | |
8GA2
 | | Bromodomain of CBP liganded with inhibitor iCBP5 | | 分子名称: | (6S)-6-{(5M)-5-(3,5-dimethyl-1,2-oxazol-4-yl)-1-[(1s,4R)-4-methoxycyclohexyl]-1H-benzimidazol-2-yl}-1-phenylpiperidin-2-one, 1,2-ETHANEDIOL, CREB-binding protein | | 著者 | Schonbrunn, E, Bikowitz, M. | | 登録日 | 2023-02-22 | | 公開日 | 2024-02-28 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Group 3 medulloblastoma transcriptional networks collapse under domain specific EP300/CBP inhibition.
Nat Commun, 15, 2024
|
|
8I4S
 | | the complex structure of SARS-CoV-2 Mpro with D8 | | 分子名称: | 3-(4-fluoranyl-3-methyl-phenyl)-2-(2-methylpropyl)-5,6,7-tris(oxidanyl)quinazolin-4-one, ORF1a polyprotein | | 著者 | Lu, M. | | 登録日 | 2023-01-21 | | 公開日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Discovery of quinazolin-4-one-based non-covalent inhibitors targeting the severe acute respiratory syndrome coronavirus 2 main protease (SARS-CoV-2 M pro ).
Eur.J.Med.Chem., 257, 2023
|
|
7FCD
 | |
7FCE
 | | Structure of the SARS-CoV-2 A372T spike glycoprotein (closed) | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein | | 著者 | Wang, X, Zhang, S. | | 登録日 | 2021-07-14 | | 公開日 | 2022-01-26 | | 最終更新日 | 2022-03-16 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | Loss of Spike N370 glycosylation as an important evolutionary event for the enhanced infectivity of SARS-CoV-2.
Cell Res., 32, 2022
|
|
8K5N
 | |
6ZY3
 | | Cryo-EM structure of MlaFEDB in complex with phospholipid | | 分子名称: | 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, ABC transporter maintaining OM lipid asymmetry, cytoplasmic STAS component, ... | | 著者 | Dong, C.J, Dong, H.H. | | 登録日 | 2020-07-30 | | 公開日 | 2020-11-25 | | 最終更新日 | 2024-05-01 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Structural insights into outer membrane asymmetry maintenance in Gram-negative bacteria by MlaFEDB.
Nat.Struct.Mol.Biol., 28, 2021
|
|
6ZY2
 | | Cryo-EM structure of apo MlaFEDB | | 分子名称: | ABC transporter maintaining OM lipid asymmetry, cytoplasmic STAS component, Toluene tolerance protein Ttg2A, ... | | 著者 | Dong, C.J, Dong, H.H. | | 登録日 | 2020-07-30 | | 公開日 | 2020-11-25 | | 最終更新日 | 2024-05-01 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Structural insights into outer membrane asymmetry maintenance in Gram-negative bacteria by MlaFEDB.
Nat.Struct.Mol.Biol., 28, 2021
|
|
6ZY4
 | | Cryo-EM structure of MlaFEDB in complex with ADP | | 分子名称: | ABC transporter maintaining OM lipid asymmetry, cytoplasmic STAS component, ADENOSINE-5'-DIPHOSPHATE, ... | | 著者 | Dong, C.J, Dong, H.H. | | 登録日 | 2020-07-30 | | 公開日 | 2020-11-25 | | 最終更新日 | 2024-05-01 | | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | | 主引用文献 | Structural insights into outer membrane asymmetry maintenance in Gram-negative bacteria by MlaFEDB.
Nat.Struct.Mol.Biol., 28, 2021
|
|
6ZY9
 | | Cryo-EM structure of MlaFEDB in complex with AMP-PNP | | 分子名称: | ABC transporter maintaining OM lipid asymmetry, cytoplasmic STAS component, MAGNESIUM ION, ... | | 著者 | Dong, C.J, Dong, H.H. | | 登録日 | 2020-07-30 | | 公開日 | 2020-11-25 | | 最終更新日 | 2024-05-01 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Structural insights into outer membrane asymmetry maintenance in Gram-negative bacteria by MlaFEDB.
Nat.Struct.Mol.Biol., 28, 2021
|
|
3L2A
 | | Crystal structure of Reston Ebola VP35 interferon inhibitory domain | | 分子名称: | ACETIC ACID, GLYCEROL, Polymerase cofactor VP35 | | 著者 | Leung, D.W, Farahbakhsh, M, Borek, D.M, Prins, K.C, Basler, C.F, Amarasinghe, G.K. | | 登録日 | 2009-12-14 | | 公開日 | 2010-05-12 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.71 Å) | | 主引用文献 | Structural and Functional Characterization of Reston Ebola Virus VP35 Interferon Inhibitory Domain.
J.Mol.Biol., 399, 2010
|
|
7CFS
 | | Cryo-EM strucutre of human acid-sensing ion channel 1a at pH 8.0 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Acid-sensing ion channel 1, CHOLESTEROL HEMISUCCINATE, ... | | 著者 | Sun, D.M, Liu, S.L, Li, S.Y, Yang, F, Tian, C.L. | | 登録日 | 2020-06-28 | | 公開日 | 2020-10-21 | | 実験手法 | ELECTRON MICROSCOPY (3.56 Å) | | 主引用文献 | Structural insights into human acid-sensing ion channel 1a inhibition by snake toxin mambalgin1.
Elife, 9, 2020
|
|
7CFT
 | | Cryo-EM strucutre of human acid-sensing ion channel 1a in complex with snake toxin Mambalgin1 at pH 8.0 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Acid-sensing ion channel 1, Mambalgin-1 | | 著者 | Sun, D.M, Liu, S.L, Li, S.Y, Yang, F, Tian, C.L. | | 登録日 | 2020-06-28 | | 公開日 | 2020-10-21 | | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | | 主引用文献 | Structural insights into human acid-sensing ion channel 1a inhibition by snake toxin mambalgin1.
Elife, 9, 2020
|
|
3RFZ
 | | Crystal structure of the FimD usher bound to its cognate FimC:FimH substrate | | 分子名称: | Chaperone protein fimC, Outer membrane usher protein, type 1 fimbrial synthesis, ... | | 著者 | Phan, G, Remaut, H, Lebedev, A, Geibel, S, Waksman, G. | | 登録日 | 2011-04-07 | | 公開日 | 2011-06-01 | | 最終更新日 | 2012-03-28 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Crystal structure of the FimD usher bound to its cognate FimC-FimH substrate.
Nature, 474, 2011
|
|
3MFE
 | |
3GBI
 | | The Rational Design and Structural Analysis of a Self-Assembled Three-Dimensional DNA Crystal | | 分子名称: | DNA (5'-D(*GP*AP*GP*CP*AP*GP*CP*CP*TP*GP*TP*AP*CP*GP*GP*AP*CP*AP*TP*CP*A)-3'), DNA (5'-D(*TP*CP*TP*GP*AP*TP*GP*T)-3'), DNA (5'-D(P*CP*CP*GP*TP*AP*CP*A)-3'), ... | | 著者 | Birktoft, J.J, Zheng, J, Seeman, N.C. | | 登録日 | 2009-02-19 | | 公開日 | 2009-09-01 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (4.018 Å) | | 主引用文献 | From molecular to macroscopic via the rational design of a self-assembled 3D DNA crystal.
Nature, 461, 2009
|
|
3MKA
 | |
3MGM
 | | Crystal structure of human NUDT16 | | 分子名称: | U8 snoRNA-decapping enzyme | | 著者 | Yan, J, Lu, G, Zhang, J, Qi, J, Li, Z, Gao, F. | | 登録日 | 2010-04-07 | | 公開日 | 2011-04-20 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.801 Å) | | 主引用文献 | Crystal structure and the template mRNA decapping activity of human NUDT16
To be Published
|
|
3MI0
 | | Crystal Structure of Mycobacterium Tuberculosis Proteasome at 2.2 A | | 分子名称: | (2R,3S,4R)-2-[(S)-(1S)-cyclohex-2-en-1-yl(hydroxy)methyl]-4-ethyl-3-hydroxy-3-methyl-5-oxopyrrolidine-2-carbaldehyde, DIMETHYLFORMAMIDE, Proteasome subunit alpha, ... | | 著者 | Li, D, Li, H. | | 登録日 | 2010-04-09 | | 公開日 | 2010-06-23 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structural basis for the assembly and gate closure mechanisms of the Mycobacterium tuberculosis 20S proteasome.
Embo J., 2010
|
|
7E80
 | | Cryo-EM structure of the flagellar rod with hook and export apparatus from Salmonella | | 分子名称: | Flagellar MS ring L1, Flagellar MS ring L2, Flagellar basal body rod protein FlgB, ... | | 著者 | Tan, J.X, Chang, S.H, Wang, X.F, Xu, C.H, Zhou, Y, Zhang, X, Zhu, Y.Q. | | 登録日 | 2021-02-28 | | 公開日 | 2021-04-28 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (3.67 Å) | | 主引用文献 | Structural basis of assembly and torque transmission of the bacterial flagellar motor.
Cell, 184, 2021
|
|
7E81
 | | Cryo-EM structure of the flagellar MS ring with FlgB-Dc loop and FliE-helix 1 from Salmonella | | 分子名称: | Flagellar M-ring protein, FlgB-Dc loop, FliE helix 1 | | 著者 | Tan, J.X, Chang, S.H, Wang, X.F, Xu, C.H, Zhou, Y, Zhang, X, Zhu, Y.Q. | | 登録日 | 2021-02-28 | | 公開日 | 2021-04-28 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (4.5 Å) | | 主引用文献 | Structural basis of assembly and torque transmission of the bacterial flagellar motor.
Cell, 184, 2021
|
|
7E82
 | | Cryo-EM structure of the flagellar rod with partial hook from Salmonella | | 分子名称: | Flagellar MS ring L1, Flagellar MS ring L2, Flagellar basal body rod protein FlgB, ... | | 著者 | Tan, J.X, Chang, S.H, Wang, X.F, Xu, C.H, Zhou, Y, Zhang, X, Zhu, Y.Q. | | 登録日 | 2021-02-28 | | 公開日 | 2021-04-28 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Structural basis of assembly and torque transmission of the bacterial flagellar motor.
Cell, 184, 2021
|
|
7WD8
 | |
7WD9
 | |
