8HP7
 
 | | Crystal structure of (S)-2-haloacid dehalogenase K152A mutant trapped with (2R)-4-amino-2-hydroxybutanoic acid | | 分子名称: | (S)-2-haloacid dehalogenase, 1,2-ETHANEDIOL, GAMMA-AMINO-BUTANOIC ACID | | 著者 | Yang, Q, Wang, L, Xu, X, Xing, X, Zhou, J. | | 登録日 | 2022-12-12 | | 公開日 | 2023-06-21 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.43 Å) | | 主引用文献 | Enzymatic hydrolysis on L-azetidine-2-carboxylate ring opening
Catalysis Science And Technology, 2023
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8I4B
 | | Cryo-EM structure of apo-form ABCC4 | | 分子名称: | ATP-binding cassette sub-family C member 4 | | 著者 | Chen, Y, Wang, L, Hou, W.T, Zhou, C.Z, Chen, Y, Li, Q. | | 登録日 | 2023-01-19 | | 公開日 | 2023-05-24 | | 実験手法 | ELECTRON MICROSCOPY (3.13 Å) | | 主引用文献 | Cryo-EM structure ofABCC4
Nat Cardiovasc Res, 2023
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8I4C
 | | Cryo-EM structure of U46619-bound ABCC4 | | 分子名称: | (5Z)-7-{(1R,4S,5S,6R)-6-[(1E,3S)-3-hydroxyoct-1-en-1-yl]-2-oxabicyclo[2.2.1]hept-5-yl}hept-5-enoic acid, ATP-binding cassette sub-family C member 4 | | 著者 | Chen, Y, Wang, L, Hou, W.T, Zhou, C.Z, Chen, Y, Li, Q. | | 登録日 | 2023-01-19 | | 公開日 | 2023-05-24 | | 実験手法 | ELECTRON MICROSCOPY (3.08 Å) | | 主引用文献 | Cryo-EM structure ofABCC4
Nat Cardiovasc Res, 2023
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8I4A
 | | Cryo-EM structure of dipyridamole-bound ABCC4 | | 分子名称: | 2-[[2-[bis(2-hydroxyethyl)amino]-4,8-di(piperidin-1-yl)pyrimido[5,4-d]pyrimidin-6-yl]-(2-hydroxyethyl)amino]ethanol, ATP-binding cassette sub-family C member 4 | | 著者 | Chen, Y, Wang, L, Hou, W.T, Zhou, C.Z, Chen, Y, Li, Q. | | 登録日 | 2023-01-19 | | 公開日 | 2023-05-24 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Cryo-EM structure ofABCC4
Nat Cardiovasc Res, 2023
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8J3W
 | | Cryo-EM structure of aspirin-bound ABCC4 | | 分子名称: | 2-(ACETYLOXY)BENZOIC ACID, ATP-binding cassette sub-family C member 4 | | 著者 | Chen, Y, Wang, L, Hou, W.T, Zhou, C.Z, Chen, Y, Li, Q. | | 登録日 | 2023-04-18 | | 公開日 | 2023-05-24 | | 実験手法 | ELECTRON MICROSCOPY (3.07 Å) | | 主引用文献 | Cryo-EM structure ofABCC4
Nat Cardiovasc Res, 2023
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8J3Z
 | | Cryo-EM structure of ATP-U46619-bound ABCC4 | | 分子名称: | (5Z)-7-{(1R,4S,5S,6R)-6-[(1E,3S)-3-hydroxyoct-1-en-1-yl]-2-oxabicyclo[2.2.1]hept-5-yl}hept-5-enoic acid, ADENOSINE-5'-TRIPHOSPHATE, ATP-binding cassette sub-family C member 4, ... | | 著者 | Chen, Y, Wang, L, Hou, W.T, Zhou, C.Z, Chen, Y, Li, Q. | | 登録日 | 2023-04-18 | | 公開日 | 2023-05-24 | | 実験手法 | ELECTRON MICROSCOPY (3.17 Å) | | 主引用文献 | Cryo-EM structure ofABCC4
Nat Cardiovasc Res, 2023
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8ISY
 | | Cryo-EM structure of free-state Crt-SPARTA | | 分子名称: | Piwi domain-containing protein, TIR domain-containing protein | | 著者 | Gao, X, Shang, K, Zhu, K, Wang, L, Mu, Z, Fu, X, Yu, X, Qin, B, Zhu, H, Ding, W, Cui, S. | | 登録日 | 2023-03-21 | | 公開日 | 2023-10-18 | | 最終更新日 | 2024-02-07 | | 実験手法 | ELECTRON MICROSCOPY (3.27 Å) | | 主引用文献 | Nucleic-acid-triggered NADase activation of a short prokaryotic Argonaute.
Nature, 625, 2024
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8IT0
 | | Cryo-EM structure of Crt-SPARTA-gRNA-tDNA dimer (conformation-2) | | 分子名称: | DNA (45-mer), Piwi domain-containing protein, RNA (5'-R(P*UP*GP*AP*GP*GP*UP*AP*GP*UP*AP*GP*GP*UP*UP*GP*UP*AP*UP*AP*GP*U)-3'), ... | | 著者 | Gao, X, Shang, K, Zhu, K, Wang, L, Mu, Z, Fu, X, Yu, X, Qin, B, Zhu, H, Ding, W, Cui, S. | | 登録日 | 2023-03-21 | | 公開日 | 2023-10-18 | | 最終更新日 | 2024-02-07 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Nucleic-acid-triggered NADase activation of a short prokaryotic Argonaute.
Nature, 625, 2024
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8ISZ
 | | Cryo-EM structure of Crt-SPARTA-gRNA-tDNA monomer | | 分子名称: | DNA (45-mer), Piwi domain-containing protein, RNA (5'-R(P*UP*GP*AP*GP*GP*UP*AP*GP*UP*AP*GP*GP*UP*UP*GP*UP*AP*UP*AP*GP*U)-3'), ... | | 著者 | Gao, X, Shang, K, Zhu, K, Wang, L, Mu, Z, Fu, X, Yu, X, Qin, B, Zhu, H, Ding, W, Cui, S. | | 登録日 | 2023-03-21 | | 公開日 | 2023-10-18 | | 最終更新日 | 2024-02-07 | | 実験手法 | ELECTRON MICROSCOPY (3.27 Å) | | 主引用文献 | Nucleic-acid-triggered NADase activation of a short prokaryotic Argonaute.
Nature, 625, 2024
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8IT1
 | | Cryo-EM structure of Crt-SPARTA-gRNA-tDNA tetramer (NADase active form) | | 分子名称: | DNA (45-mer), Piwi domain-containing protein, RNA (5'-R(P*UP*GP*AP*GP*GP*UP*AP*GP*UP*AP*GP*GP*UP*UP*GP*UP*AP*UP*AP*GP*U)-3'), ... | | 著者 | Gao, X, Shang, K, Zhu, K, Wang, L, Mu, Z, Fu, X, Yu, X, Qin, B, Zhu, H, Ding, W, Cui, S. | | 登録日 | 2023-03-21 | | 公開日 | 2023-11-08 | | 最終更新日 | 2024-02-07 | | 実験手法 | ELECTRON MICROSCOPY (3.41 Å) | | 主引用文献 | Nucleic-acid-triggered NADase activation of a short prokaryotic Argonaute.
Nature, 625, 2024
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8J1K
 | | co-crystal structure of non-carboxylic acid inhibitor with PHD2 | | 分子名称: | Egl nine homolog 1, MANGANESE (II) ION, N-[(6-cyanopyridin-3-yl)methyl]-5-oxidanyl-2-[(3R)-3-oxidanylpyrrolidin-1-yl]-1,7-naphthyridine-6-carboxamide | | 著者 | Xu, J, Fu, Y, Ding, X, Meng, Q, Wang, L, Zhang, M, Ding, X, Ren, F, Zhavoronkov, A. | | 登録日 | 2023-04-13 | | 公開日 | 2024-04-17 | | 実験手法 | X-RAY DIFFRACTION (2.451 Å) | | 主引用文献 | co-crystal structure of non-carboxylic acid inhibitor with PHD2
To Be Published
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8K4W
 | | Structure of a triple-helix region of human collagen type I from Trautec | | 分子名称: | CHLORIDE ION, triple-helix region of human collagen type I | | 著者 | Chu, Y, Zhai, Y, Fan, X, Li, J, Wang, L, Fu, S, Feng, P, Qian, S. | | 登録日 | 2023-07-20 | | 公開日 | 2023-08-02 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Structure of a triple-helix region of human collagen type I from Trautec.
To Be Published
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8K4Y
 | | Structure of a triple-helix region of human ReCol 3 from Trautec | | 分子名称: | SULFATE ION, triple-helix region of human ReCol 3 | | 著者 | Chu, Y, Zhai, Y, Fan, X, Li, J, Wang, L, Fu, S, Feng, P, Qian, S. | | 登録日 | 2023-07-20 | | 公開日 | 2023-08-02 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Structure of a triple-helix region of human ReCol 3 from Trautec.
To Be Published
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8K4X
 | | Structure of a triple-helix region of human Collagen type XVII from Trautec | | 分子名称: | triple-helix region of human Collagen type XVII | | 著者 | Chu, Y, Zhai, Y, Fan, X, Li, J, Wang, L, Fu, S, Feng, P, Qian, S. | | 登録日 | 2023-07-20 | | 公開日 | 2023-08-02 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | | 主引用文献 | Structure of a triple-helix region of human Collagen type XVII from Trautec.
To Be Published
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8K9G
 | | Cryo-EM structure of Crt-SPARTA-gRNA-tDNA dimer (conformation-1) | | 分子名称: | DNA (45-mer), Piwi domain-containing protein, RNA (5'-R(P*UP*GP*AP*GP*GP*UP*AP*GP*UP*AP*GP*GP*UP*UP*GP*UP*AP*UP*AP*GP*U)-3'), ... | | 著者 | Gao, X, Shang, K, Zhu, K, Wang, L, Mu, Z, Fu, X, Yu, X, Qin, B, Zhu, H, Ding, W, Cui, S. | | 登録日 | 2023-08-01 | | 公開日 | 2023-10-18 | | 最終更新日 | 2024-02-07 | | 実験手法 | ELECTRON MICROSCOPY (3.49 Å) | | 主引用文献 | Nucleic-acid-triggered NADase activation of a short prokaryotic Argonaute.
Nature, 625, 2024
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7XKC
 | | Crystal structure of Daucus Carrot hypoglycemic peptide (DCHP) | | 分子名称: | DCHP, SULFATE ION | | 著者 | Guo, T, Ren, J.Q, Wang, L, Shi, Y.W, Feng, W. | | 登録日 | 2022-04-19 | | 公開日 | 2022-05-18 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.56 Å) | | 主引用文献 | Characterization of a thermostable, protease-tolerant inhibitor of alpha-glycosidase from carrot: A potential oral additive for treatment of diabetes.
Int.J.Biol.Macromol., 209, 2022
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7VFB
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7VFA
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7VZB
 | | Cryo-EM structure of C22:0-CoA bound human very long-chain fatty acid ABC transporter ABCD1 | | 分子名称: | CHOLESTEROL HEMISUCCINATE, Peroxisomal Membrane Protein related,ATP-binding cassette sub-family D member 1, S-[2-[3-[[(2R)-4-[[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-4-oxidanyl-3-phosphonooxy-oxolan-2-yl]methoxy-oxidanyl-phosphoryl]oxy-oxidanyl-phosphoryl]oxy-3,3-dimethyl-2-oxidanyl-butanoyl]amino]propanoylamino]ethyl] docosanethioate | | 著者 | Chen, Z.P, Xu, D, Wang, L, Mao, Y.X, Yang, L, Cheng, M.T, Hou, W.T, Chen, Y.X, Zhou, C.Z. | | 登録日 | 2021-11-15 | | 公開日 | 2022-05-18 | | 最終更新日 | 2022-06-22 | | 実験手法 | ELECTRON MICROSCOPY (3.59 Å) | | 主引用文献 | Structural basis of substrate recognition and translocation by human very long-chain fatty acid transporter ABCD1.
Nat Commun, 13, 2022
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7VWC
 | | Cryo-EM structure of human very long-chain fatty acid ABC transporter ABCD1 | | 分子名称: | Peroxisomal Membrane Protein related,ATP-binding cassette sub-family D member 1, [(2R)-3-[2-azanylethoxy(oxidanyl)phosphoryl]oxy-2-oxidanyl-propyl] octadecanoate | | 著者 | Chen, Z.P, Xu, D, Wang, L, Mao, Y.X, Yang, L, Cheng, M.T, Hou, W.T, Chen, Y.X, Zhou, C.Z. | | 登録日 | 2021-11-10 | | 公開日 | 2022-05-18 | | 最終更新日 | 2022-06-22 | | 実験手法 | ELECTRON MICROSCOPY (3.53 Å) | | 主引用文献 | Structural basis of substrate recognition and translocation by human very long-chain fatty acid transporter ABCD1.
Nat Commun, 13, 2022
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7VX8
 | | Cryo-EM structure of ATP-bound human very long-chain fatty acid ABC transporter ABCD1 | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Peroxisomal Membrane Protein related,ATP-binding cassette sub-family D member 1 | | 著者 | Chen, Z.P, Xu, D, Wang, L, Mao, Y.X, Yang, L, Cheng, M.T, Hou, W.T, Chen, Y.X, Zhou, C.Z. | | 登録日 | 2021-11-12 | | 公開日 | 2022-05-18 | | 最終更新日 | 2022-06-22 | | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | | 主引用文献 | Structural basis of substrate recognition and translocation by human very long-chain fatty acid transporter ABCD1.
Nat Commun, 13, 2022
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7D1G
 | | Crystal structure of Glyceraldehyde-3-Phosphate Dehydrogenase GAPDH from Clostridium beijerinckii | | 分子名称: | BETA-MERCAPTOETHANOL, Glyceraldehyde-3-phosphate dehydrogenase, MAGNESIUM ION | | 著者 | Chen, Y, Lan, J, Liu, W, Wang, L, Xu, Y. | | 登録日 | 2020-09-14 | | 公開日 | 2021-03-17 | | 実験手法 | X-RAY DIFFRACTION (1.58 Å) | | 主引用文献 | Crystal structure of Glyceraldehyde-3-Phosphate Dehydrogenase GAPDH from Clostridium beijerinckii
To Be Published
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7CYE
 | | Cryo-EM structure of sodium-dependent bicarbonate transporter SbtA from Synechocystis sp. PCC 6803 | | 分子名称: | Slr1512 protein | | 著者 | Liu, X.Y, Jiang, Y.L, Wang, L, Hou, W.T, Chen, Y, Zhou, C.Z. | | 登録日 | 2020-09-03 | | 公開日 | 2021-06-23 | | 最終更新日 | 2022-02-16 | | 実験手法 | ELECTRON MICROSCOPY (3.54 Å) | | 主引用文献 | Structures of cyanobacterial bicarbonate transporter SbtA and its complex with PII-like SbtB.
Cell Discov, 7, 2021
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7CYF
 | | Cryo-EM structure of bicarbonate transporter SbtA in complex with PII-like signaling protein SbtB from Synechocystis sp. PCC 6803 | | 分子名称: | ADENOSINE MONOPHOSPHATE, Membrane-associated protein slr1513, SODIUM ION, ... | | 著者 | Liu, X.Y, Jiang, Y.L, Wang, L, Hou, W.T, Chen, Y, Zhou, C.Z. | | 登録日 | 2020-09-03 | | 公開日 | 2021-06-23 | | 最終更新日 | 2022-02-16 | | 実験手法 | ELECTRON MICROSCOPY (3.15 Å) | | 主引用文献 | Structures of cyanobacterial bicarbonate transporter SbtA and its complex with PII-like SbtB.
Cell Discov, 7, 2021
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7DUO
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