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Crystal Structure of VN01H1 Fab in complex with SARS-CoV-2 S fusion peptide
Descriptor:	Heavy chain of VN01H1 Fab, Light chain of VN01H1 Fab, PRO-SER-LYS-ARG-SER-PHE-ILE-GLU-ASP-LEU-LEU-PHE-ASN
Authors:	Tortorici, M.A, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2021-10-22
Release date:	2022-07-20
Last modified:	2023-10-18
Method:	X-RAY DIFFRACTION (1.86 Å)
Cite:	ACE2-binding exposes the SARS-CoV-2 fusion peptide to broadly neutralizing coronavirus antibodies. Science, 377, 2022

7SO9

SARS-CoV-2 S B.1.617.2 delta variant + S2M11 + S2L20 Global Refinement
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, S2L20 Fab heavy chain, S2L20 Fab light chain, ...
Authors:	McCallum, M, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2021-10-29
Release date:	2021-11-17
Last modified:	2022-01-05
Method:	ELECTRON MICROSCOPY (2.4 Å)
Cite:	Molecular basis of immune evasion by the Delta and Kappa SARS-CoV-2 variants. Science, 374, 2021

7SOC

SARS-CoV-2 S RBD B.1.617.1 kappa variant S309 Local Refinement
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, S309 Fab heavy chain, S309 Fab light chain, ...
Authors:	McCallum, M, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2021-10-29
Release date:	2021-11-17
Last modified:	2022-01-05
Method:	ELECTRON MICROSCOPY (3.3 Å)
Cite:	Molecular basis of immune evasion by the Delta and Kappa SARS-CoV-2 variants. Science, 374, 2021

7SOD

SARS-CoV-2 S NTD B.1.617.1 kappa variant S2L20 Local Refinement
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, S2L20 Fab heavy chain, ...
Authors:	McCallum, M, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2021-10-29
Release date:	2021-11-17
Last modified:	2022-01-05
Method:	ELECTRON MICROSCOPY (3.2 Å)
Cite:	Molecular basis of immune evasion by the Delta and Kappa SARS-CoV-2 variants. Science, 374, 2021

8ERQ

SARS-CoV-2 BA.1 spike ectodomain trimer in complex with the S2X324 neutralizing antibody Fab fragment (local refinement of the RBD and S2X324)
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, S2X324 Fab heavy chain, S2X324 Fab light chain, ...
Authors:	Park, Y.J, Seattle Structural Genomics Center for Infectious Disease (SSGCID), Veesler, D.
Deposit date:	2022-10-12
Release date:	2022-10-26
Last modified:	2022-11-23
Method:	ELECTRON MICROSCOPY (3.3 Å)
Cite:	Imprinted antibody responses against SARS-CoV-2 Omicron sublineages. Science, 378, 2022

8DYA

Structure of the SARS-CoV-2 spike glycoprotein S2 subunit
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
Authors:	Park, Y.J, Seattle Structural Genomics Center for Infectious Disease (SSGCID), Veesler, D.
Deposit date:	2022-08-03
Release date:	2022-11-30
Last modified:	2023-01-11
Method:	ELECTRON MICROSCOPY (3.67 Å)
Cite:	SARS-CoV-2 spike conformation determines plasma neutralizing activity elicited by a wide panel of human vaccines. Sci Immunol, 7, 2022

7TLZ

SARS-CoV-2 S NTD B.1.1.529 Omicron variant + S309 Local Refinement
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, S2L20 Fab heavy chain, S2L20 Fab light chain, ...
Authors:	McCallum, M, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2022-01-19
Release date:	2022-02-02
Last modified:	2022-03-09
Method:	ELECTRON MICROSCOPY (3.3 Å)
Cite:	Structural basis of SARS-CoV-2 Omicron immune evasion and receptor engagement. Science, 375, 2022

7TAT

SARS-CoV-2 spike in complex with the S2K146 neutralizing antibody Fab fragment (two receptor-binding domains open)
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, S2K146 Fab heavy chain, ...
Authors:	Park, Y.J, Seattle Structural Genomics Center for Infectious Disease (SSGCID), Veesler, D.
Deposit date:	2021-12-21
Release date:	2022-01-12
Last modified:	2022-02-09
Method:	ELECTRON MICROSCOPY (3.2 Å)
Cite:	Antibody-mediated broad sarbecovirus neutralization through ACE2 molecular mimicry. Science, 375, 2022

7TAS

SARS-CoV-2 spike in complex with the S2K146 neutralizing antibody Fab fragment (local refinement of the RBD and S2K146)
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, S2K146 Fab heavy chain, S2K146 Fab light chain, ...
Authors:	Park, Y.J, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2021-12-21
Release date:	2022-01-12
Last modified:	2022-02-09
Method:	ELECTRON MICROSCOPY (3.2 Å)
Cite:	Antibody-mediated broad sarbecovirus neutralization through ACE2 molecular mimicry. Science, 375, 2022

7TLY

SARS-CoV-2 S B.1.1.529 Omicron variant (RBD + S309 Local Refinement)
Descriptor:	S309 Fab heavy chain, S309 Fab light chain, Spike glycoprotein, ...
Authors:	McCallum, M, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2022-01-19
Release date:	2022-02-02
Last modified:	2022-03-09
Method:	ELECTRON MICROSCOPY (3 Å)
Cite:	Structural basis of SARS-CoV-2 Omicron immune evasion and receptor engagement. Science, 375, 2022

7TM0

SARS-CoV-2 S B.1.1.529 Omicron variant + S309 + S2L20 Global Refinement
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, S2L20 Fab heavy chain, ...
Authors:	McCallum, M, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2022-01-19
Release date:	2022-02-02
Last modified:	2022-03-09
Method:	ELECTRON MICROSCOPY (3.1 Å)
Cite:	Structural basis of SARS-CoV-2 Omicron immune evasion and receptor engagement. Science, 375, 2022

7TN0

SARS-CoV-2 Omicron RBD in complex with human ACE2 and S304 Fab and S309 Fab
Descriptor:	1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, ...
Authors:	McCallum, M, Czudnochowski, N, Nix, J.C, Croll, T.I, SSGCID, Dillen, J.R, Snell, G, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2022-01-20
Release date:	2022-02-02
Last modified:	2023-10-18
Method:	X-RAY DIFFRACTION (2.85 Å)
Cite:	Structural basis of SARS-CoV-2 Omicron immune evasion and receptor engagement. Science, 375, 2022

7U0A

Crystal Structure of C77G12 Fab in complex with SARS-CoV-2 S fusion peptide
Descriptor:	CHLORIDE ION, Heavy chain Fab C77G12, Light chain Fab C77G12, ...
Authors:	Tortorici, M.A, Veesler, D.
Deposit date:	2022-02-17
Release date:	2022-08-03
Last modified:	2023-10-18
Method:	X-RAY DIFFRACTION (1.7 Å)
Cite:	ACE2-binding exposes the SARS-CoV-2 fusion peptide to broadly neutralizing coronavirus antibodies. Science, 377, 2022

7U0E

Crystal Structure of C13C9 Fab in complex with SARS-CoV-2 S fusion peptide
Descriptor:	Heavy chain Fab C13C9, Light chain Fab C13C9, SARS-CoV-2 S fusion peptide
Authors:	Tortorici, M.A, Veesler, D.
Deposit date:	2022-02-18
Release date:	2022-08-03
Last modified:	2023-10-18
Method:	X-RAY DIFFRACTION (2.1 Å)
Cite:	ACE2-binding exposes the SARS-CoV-2 fusion peptide to broadly neutralizing coronavirus antibodies. Science, 377, 2022

7U09

Crystal Structure of C13B8 Fab in complex with SARS-CoV-2 S fusion peptide
Descriptor:	Heavy chain Fab C13B8, Light chain Fab C13B8, SARS-CoV-2 S fusion peptide
Authors:	Tortorici, M.A, Veesler, D.
Deposit date:	2022-02-17
Release date:	2022-08-03
Last modified:	2023-10-18
Method:	X-RAY DIFFRACTION (2.1 Å)
Cite:	ACE2-binding exposes the SARS-CoV-2 fusion peptide to broadly neutralizing coronavirus antibodies. Science, 377, 2022

7U0L

Crystal structure of the CCoV-HuPn-2018 RBD (domain B) in complex with canine APN
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Aminopeptidase N, ...
Authors:	Tortorici, M.A, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2022-02-18
Release date:	2022-08-24
Last modified:	2023-10-18
Method:	X-RAY DIFFRACTION (3.3 Å)
Cite:	Structure, receptor recognition, and antigenicity of the human coronavirus CCoV-HuPn-2018 spike glycoprotein. Cell, 185, 2022

7U6R

Cryo-EM structure of PDF-2180 Spike glycoprotein
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, PDF-2180 Spike glycoprotein
Authors:	Tortorici, M.A, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2022-03-05
Release date:	2022-11-30
Last modified:	2023-01-04
Method:	ELECTRON MICROSCOPY (2.5 Å)
Cite:	Close relatives of MERS-CoV in bats use ACE2 as their functional receptors. Nature, 612, 2022

7USB

CCoV-HuPn-2018 S in the swung out conformation (local refinement of domain 0)
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
Authors:	Tortorici, M.A, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2022-04-23
Release date:	2022-08-24
Method:	ELECTRON MICROSCOPY (3.1 Å)
Cite:	Structure, receptor recognition, and antigenicity of the human coronavirus CCoV-HuPn-2018 spike glycoprotein. Cell, 185, 2022

7US9

CCoV-HuPn-2018 S in the proximal conformation (local refinement of domain 0)
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
Authors:	Tortorici, M.A, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2022-04-23
Release date:	2022-08-24
Method:	ELECTRON MICROSCOPY (3.8 Å)
Cite:	Structure, receptor recognition, and antigenicity of the human coronavirus CCoV-HuPn-2018 spike glycoprotein. Cell, 185, 2022

7USA

Structure of the human coronavirus CCoV-HuPn-2018 spike glycoprotein with domain 0 in the swung out conformation
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ...
Authors:	Tortorici, M.A, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2022-04-23
Release date:	2022-08-24
Method:	ELECTRON MICROSCOPY (2.8 Å)
Cite:	Structure, receptor recognition, and antigenicity of the human coronavirus CCoV-HuPn-2018 spike glycoprotein. Cell, 185, 2022

7US6

Structure of the human coronavirus CCoV-HuPn-2018 spike glycoprotein with domain 0 in the proximal conformation
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ...
Authors:	Tortorici, M.A, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2022-04-23
Release date:	2022-08-24
Method:	ELECTRON MICROSCOPY (3.8 Å)
Cite:	Structure, receptor recognition, and antigenicity of the human coronavirus CCoV-HuPn-2018 spike glycoprotein. Cell, 185, 2022

7JZL

SARS-CoV-2 spike in complex with LCB1 (2RBDs open)
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, LCB1, ...
Authors:	Park, Y.J, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2020-09-02
Release date:	2020-09-23
Last modified:	2020-11-04
Method:	ELECTRON MICROSCOPY (2.7 Å)
Cite:	De novo design of picomolar SARS-CoV-2 miniprotein inhibitors. Science, 370, 2020

7JZN

SARS-CoV-2 spike in complex with LCB3 (2RBDs open)
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, LCB3, ...
Authors:	Park, Y.J, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2020-09-02
Release date:	2020-09-23
Last modified:	2020-11-04
Method:	ELECTRON MICROSCOPY (3.1 Å)
Cite:	De novo design of picomolar SARS-CoV-2 miniprotein inhibitors. Science, 370, 2020

7JZM

SARS-CoV-2 spike in complex with LCB3 (local refinement of the RBD and LCB3)
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, LCB3, Spike glycoprotein
Authors:	Park, Y.J, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2020-09-02
Release date:	2020-09-23
Last modified:	2020-11-04
Method:	ELECTRON MICROSCOPY (3.5 Å)
Cite:	De novo design of picomolar SARS-CoV-2 miniprotein inhibitors. Science, 370, 2020

7JZU

SARS-CoV-2 spike in complex with LCB1 (local refinement of the RBD and LCB1)
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, LCB1, Spike glycoprotein
Authors:	Park, Y.J, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2020-09-02
Release date:	2020-09-23
Last modified:	2020-11-04
Method:	ELECTRON MICROSCOPY (3.1 Å)
Cite:	De novo design of picomolar SARS-CoV-2 miniprotein inhibitors. Science, 370, 2020

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