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6WPT
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Structure of the SARS-CoV-2 spike glycoprotein in complex with the S309 neutralizing antibody Fab fragment (open state)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, S309 neutralizing antibody heavy chain, ...
著者Pinto, D, Park, Y.J, Beltramello, M, Walls, A.C, Tortorici, M.A, Bianchi, S, Jaconi, S, Culap, K, Zatta, F, De Marco, A, Peter, A, Guarino, B, Spreafico, R, Cameroni, E, Case, J.B, Chen, R.E, Havenar-Daughton, C, Snell, G, Virgin, H.W, Lanzavecchia, A, Diamond, M.S, Fink, K, Veesler, D, Corti, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2020-04-27
公開日2020-05-27
最終更新日2021-05-19
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Cross-neutralization of SARS-CoV-2 by a human monoclonal SARS-CoV antibody.
Nature, 583, 2020
6WPS
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BU of 6wps by Molmil
Structure of the SARS-CoV-2 spike glycoprotein in complex with the S309 neutralizing antibody Fab fragment
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, S309 neutralizing antibody heavy chain, ...
著者Pinto, D, Park, Y.J, Beltramello, M, Walls, A.C, Tortorici, M.A, Bianchi, S, Jaconi, S, Culap, K, Zatta, F, De Marco, A, Peter, A, Guarino, B, Spreafico, R, Cameroni, E, Case, J.B, Chen, R.E, Havenar-Daughton, C, Snell, G, Virgin, H.W, Lanzavecchia, A, Diamond, M.S, Fink, K, Veesler, D, Corti, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2020-04-27
公開日2020-05-27
最終更新日2021-05-19
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Cross-neutralization of SARS-CoV-2 by a human monoclonal SARS-CoV antibody.
Nature, 583, 2020
6WS6
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Structural and functional analysis of a potent sarbecovirus neutralizing antibody
分子名称: O-(O-(2-AMINOPROPYL)-O'-(2-METHOXYETHYL)POLYPROPYLENE GLYCOL 500), S309 antigen-binding (Fab) fragment, heavy chain, ...
著者Pinto, D, Park, Y.J, Beltramello, M, Walls, A.C, Tortorici, M.A, Bianchi, S, Jaconi, S, Culap, K, Zatta, F, Marco, A.D, Peter, A, Guarino, B, Spreafico, R, Cameroni, E, Case, J.B, Chen, R.E, Havenar-Daughton, C, Snell, G, Telenti, A, Virgin, H.W, Lanzavecchia, A, Diamond, M.S, Fink, K, Veesler, D, Corti, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2020-04-30
公開日2020-05-27
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Cross-neutralization of SARS-CoV-2 by a human monoclonal SARS-CoV antibody.
Nature, 583, 2020
2ABO
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BU of 2abo by Molmil
NMR structure of gamma herpesvirus 68 a viral Bcl-2 homolog
分子名称: bcl-2 homolog
著者Loh, J, Huang, Q, Petros, A.M, Nettesheim, D, van Dyk, L.F, Labrada, L, Speck, S.H, Levine, B, Olejniczak, E.T, Virgin, H.W.
登録日2005-07-15
公開日2006-05-16
最終更新日2022-03-09
実験手法SOLUTION NMR
主引用文献A surface groove essential for viral Bcl-2 function during chronic infection in vivo.
Plos Pathog., 1, 2005
1Q59
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BU of 1q59 by Molmil
Solution Structure of the BHRF1 Protein From Epstein-Barr Virus, a Homolog of Human Bcl-2
分子名称: Early antigen protein R
著者Huang, Q, Petros, A.M, Virgin, H.W, Fesik, S.W, Olejniczak, E.T.
登録日2003-08-06
公開日2003-09-23
最終更新日2022-03-02
実験手法SOLUTION NMR
主引用文献Solution Structure of the BHRF1 Protein From Epstein-Barr Virus, a Homolog of Human Bcl-2
J.Mol.Biol., 332, 2003
1K3K
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BU of 1k3k by Molmil
Solution Structure of a Bcl-2 Homolog from Kaposi's Sarcoma Virus
分子名称: functional anti-apoptotic factor vBCL-2 homolog
著者Huang, Q, Petros, A.M, Virgin, H.W, Fesik, S.W, Olejniczak, E.T.
登録日2001-10-03
公開日2002-04-10
最終更新日2021-10-27
実験手法SOLUTION NMR
主引用文献Solution structure of a Bcl-2 homolog from Kaposi sarcoma virus.
Proc.Natl.Acad.Sci.USA, 99, 2002
6CRJ
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BU of 6crj by Molmil
Mouse norovirus model using the crystal structure of MNV P domain and the Norwalkvirus shell domain
分子名称: Norwalk virus, MNV-1 capsid protein chimera
著者Smith, T.J.
登録日2018-03-19
公開日2018-04-04
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (8 Å)
主引用文献Structural basis for murine norovirus engagement of bile acids and the CD300lf receptor.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
7R6X
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SARS-CoV-2 spike receptor-binding domain (RBD) in complex with S2E12 Fab, S309 Fab, and S304 Fab
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, Monoclonal antibody S2E12 Fab heavy chain, ...
著者Snell, G, Czudnochowski, N, Croll, T.I, Nix, J.C, Corti, D, Cameroni, E, Pinto, D, Beltramello, M.
登録日2021-06-23
公開日2021-07-21
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献SARS-CoV-2 RBD antibodies that maximize breadth and resistance to escape.
Nature, 597, 2021
5FFL
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BU of 5ffl by Molmil
Crystal structure of mouse CD300lf at 1.6 Angstroms resolution.
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CD300 antigen-like family member F, ...
著者Nelson, C.A, Fremont, D.H.
登録日2015-12-18
公開日2016-08-31
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.602 Å)
主引用文献Discovery of a proteinaceous cellular receptor for a norovirus.
Science, 353, 2016
6E47
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BU of 6e47 by Molmil
Crystal Structure of the Murine Norovirus VP1 P domain in complex with the CD300lf Receptor and Glycochenodeoxycholic Acid
分子名称: 1,2-ETHANEDIOL, CMRF35-like molecule 1, GLYCOCHENODEOXYCHOLIC ACID, ...
著者Nelson, C.A, Fremont, D.H.
登録日2018-07-16
公開日2018-09-12
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structural basis for murine norovirus engagement of bile acids and the CD300lf receptor.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6E48
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BU of 6e48 by Molmil
Crystal Structure of the Murine Norovirus VP1 P domain in complex with the CD300lf Receptor and Lithocholic Acid
分子名称: (3beta,5beta,14beta,17alpha)-3-hydroxycholan-24-oic acid, 1,2-ETHANEDIOL, CALCIUM ION, ...
著者Nelson, C.A, Fremont, D.H.
登録日2018-07-16
公開日2018-09-12
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.801 Å)
主引用文献Structural basis for murine norovirus engagement of bile acids and the CD300lf receptor.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6P4L
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BU of 6p4l by Molmil
Bile salts alter the mouse norovirus capsid conformation; possible implications for cell attachment and immune evasion.
分子名称: Capsid protein
著者Smith, T.J.
登録日2019-05-28
公開日2019-08-07
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Bile Salts Alter the Mouse Norovirus Capsid Conformation: Possible Implications for Cell Attachment and Immune Evasion.
J.Virol., 93, 2019
6P4J
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BU of 6p4j by Molmil
Mouse norovirus complexed with GCDCA
分子名称: Capsid protein, GLYCOCHENODEOXYCHOLIC ACID
著者Smith, T.J, Smith, T.J.
登録日2019-05-27
公開日2019-08-07
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Bile Salts Alter the Mouse Norovirus Capsid Conformation: Possible Implications for Cell Attachment and Immune Evasion.
J.Virol., 93, 2019
6P4K
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BU of 6p4k by Molmil
mouse norovirus complexed with TCA
分子名称: Capsid protein, TAUROCHOLIC ACID
著者Smith, T.J.
登録日2019-05-27
公開日2019-08-07
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Bile Salts Alter the Mouse Norovirus Capsid Conformation: Possible Implications for Cell Attachment and Immune Evasion.
J.Virol., 93, 2019
7N8I
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BU of 7n8i by Molmil
SARS-CoV-2 S (B.1.429 / epsilon variant) + S2M11 + S2L20 (Local Refinement of the NTD/S2L20)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, S2L20 Fab Heavy Chain Variable Region, S2L20 Fab Light Chain Variable Region, ...
著者McCallum, M, Seattle Structural Genomics Center for Infectious Disease (SSGCID), Veesler, D.
登録日2021-06-14
公開日2021-07-14
最終更新日2021-08-18
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献SARS-CoV-2 immune evasion by the B.1.427/B.1.429 variant of concern.
Science, 373, 2021
7N8H
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BU of 7n8h by Molmil
SARS-CoV-2 S (B.1.429 / epsilon variant) + S2M11 + S2L20 Global Refinement
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者McCallum, M, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2021-06-14
公開日2021-07-14
最終更新日2021-08-18
実験手法ELECTRON MICROSCOPY (2.3 Å)
主引用文献SARS-CoV-2 immune evasion by the B.1.427/B.1.429 variant of concern.
Science, 373, 2021
7R6W
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BU of 7r6w by Molmil
SARS-CoV-2 spike receptor-binding domain (RBD) in complex with S2X35 Fab and S309 Fab
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, GLYCEROL, ...
著者Snell, G, Czudnochowski, N, Hernandez, P, Nix, J.C, Croll, T.I, Corti, D, Cameroni, E, Pinto, D, Beltramello, M.
登録日2021-06-23
公開日2021-07-21
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.83 Å)
主引用文献SARS-CoV-2 RBD antibodies that maximize breadth and resistance to escape.
Nature, 597, 2021
7R7N
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BU of 7r7n by Molmil
SARS-CoV-2 spike in complex with the S2D106 neutralizing antibody Fab fragment (local refinement of the RBD and S2D106)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, S2D106 FAB heavy chain, S2D106 FAB light chain, ...
著者Park, Y.J, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2021-06-25
公開日2021-07-21
最終更新日2021-09-15
実験手法ELECTRON MICROSCOPY (3.95 Å)
主引用文献SARS-CoV-2 RBD antibodies that maximize breadth and resistance to escape.
Nature, 597, 2021
7RA8
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BU of 7ra8 by Molmil
SARS-CoV-2 S glycoprotein in complex with S2X259 Fab
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain Fab S2X259 Fab variable domain, ...
著者Veesler, D, Tortorici, M.A, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2021-06-30
公開日2021-08-04
最終更新日2021-09-15
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Broad sarbecovirus neutralization by a human monoclonal antibody.
Nature, 597, 2021
7RAL
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BU of 7ral by Molmil
SARS-CoV-2 S bound to S2X259 Fab (local refinement of the RBD/S2X259 variable domains)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, S2X259 Fab heavy chain, S2X259 Fab light chain, ...
著者Veesler, D, Tortorici, M.A, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2021-07-01
公開日2021-08-04
最終更新日2021-09-15
実験手法ELECTRON MICROSCOPY
主引用文献Broad sarbecovirus neutralization by a human monoclonal antibody.
Nature, 597, 2021
7RNJ
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S2P6 Fab fragment bound to the SARS-CoV/SARS-CoV-2 spike stem helix peptide
分子名称: Monoclonal antibody S2P6 Fab heavy chain, Monoclonal antibody S2P6 Fab light chain, SULFATE ION, ...
著者Snell, G, Czudnochowski, N, Croll, T.I, Nix, J.C, Corti, D, Cameroni, E, Pinto, D, Beltramello, M, Sauer, M.M, Veesler, D.
登録日2021-07-29
公開日2021-08-11
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.67 Å)
主引用文献Broad betacoronavirus neutralization by a stem helix-specific human antibody.
Science, 373, 2021
1ML0
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BU of 1ml0 by Molmil
VIRAL CHEMOKINE BINDING PROTEIN M3 FROM MURINE GAMMAHERPESVIRUS68 IN COMPLEX WITH THE P8A VARIANT OF CC-CHEMOKINE MCP-1
分子名称: M3 Protein, Small Inducible Cytokine
著者Alexander, J.M, Fremont, D.H.
登録日2002-08-29
公開日2002-11-13
最終更新日2021-10-27
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural Basis of Chemokine Sequestration by a Herpesvirus Decoy Receptor
Cell(Cambridge,Mass.), 111, 2002
1MKF
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VIRAL CHEMOKINE BINDING PROTEIN M3 FROM MURINE GAMMAHERPESVIRUS 68
分子名称: M3
著者Alexander, J.M, Fremont, D.H, Midwest Center for Structural Genomics (MCSG)
登録日2002-08-29
公開日2002-11-13
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural Basis of Chemokine Sequestration by a Herpesvirus Decoy Receptor
Cell(Cambridge,Mass.), 111, 2002
2MCD
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BU of 2mcd by Molmil
Backbone 1H, 13C, and 15N Chemical Shift Assignments for murine norovirus NS1/2 D94E mutant
分子名称: Murine norovirus 1
著者Borin, B, Krezel, A.M.
登録日2013-08-18
公開日2013-12-18
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Murine norovirus protein NS1/2 aspartate to glutamate mutation, sufficient for persistence, reorients side chain of surface exposed tryptophan within a novel structured domain.
Proteins, 82, 2014
2MCH
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Backbone 1H, 13C, and 15N Chemical Shift Assignments for murine norovirus NS1/2 CW3 WT
分子名称: Murine norovirus 1
著者Borin, B, Krezel, A.M.
登録日2013-08-20
公開日2013-12-18
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Murine norovirus protein NS1/2 aspartate to glutamate mutation, sufficient for persistence, reorients side chain of surface exposed tryptophan within a novel structured domain.
Proteins, 82, 2014

 

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