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1B3B
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BU of 1b3b by Molmil
THERMOTOGA MARITIMA GLUTAMATE DEHYDROGENASE MUTANT N97D, G376K
分子名称: PROTEIN (GLUTAMATE DEHYDROGENASE)
著者Knapp, S, Lebbink, J.H.G, Van Der Oost, J, Devos, W.M, Rice, D, Ladenstein, R.
登録日1998-12-07
公開日1999-12-08
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Engineering activity and stability of Thermotoga maritima glutamate dehydrogenase. I. Introduction of a six-residue ion-pair network in the hinge region.
J.Mol.Biol., 280, 1998
5NG6
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BU of 5ng6 by Molmil
Crystal structure of FnCas12a bound to a crRNA
分子名称: CRISPR-associated endonuclease Cpf1, MAGNESIUM ION, crRNA
著者Swarts, D.C, van der Oost, J, Jinek, M.
登録日2017-03-16
公開日2017-06-14
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (3.342 Å)
主引用文献Structural Basis for Guide RNA Processing and Seed-Dependent DNA Targeting by CRISPR-Cas12a.
Mol. Cell, 66, 2017
5FRD
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BU of 5frd by Molmil
Structure of a thermophilic esterase
分子名称: CARBOXYLESTERASE (EST-2), CHLORIDE ION, CITRATE ANION, ...
著者Sayer, C, Finnigan, W, Isupov, M.N, Levisson, M, Kengen, S.W.M, van der Oost, J, Harmer, N, Littlechild, J.A.
登録日2015-12-17
公開日2016-05-25
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Structural and Biochemical Characterisation of Archaeoglobus Fulgidus Esterase Reveals a Bound Coa Molecule in the Vicinity of the Active Site.
Sci.Rep., 6, 2016
6QZK
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BU of 6qzk by Molmil
Structure of Clostridium butyricum Argonaute bound to a guide DNA (5' deoxycytidine) and a 19-mer target DNA
分子名称: Clostridium butyricum Argonaute, DNA target (5'-D(T*AP*TP*AP*CP*AP*AP*CP*CP*TP*AP*CP*TP*AP*CP*CP*TP*CP*T)-3'), FORMIC ACID, ...
著者Swarts, D.C, Jinek, M, Hegge, J.W, Van der Oost, J.
登録日2019-03-11
公開日2019-04-24
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (3.548 Å)
主引用文献DNA-guided DNA cleavage at moderate temperatures by Clostridium butyricum Argonaute.
Nucleic Acids Res., 47, 2019
1I9B
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BU of 1i9b by Molmil
X-RAY STRUCTURE OF ACETYLCHOLINE BINDING PROTEIN (ACHBP)
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ACETYLCHOLINE BINDING PROTEIN, CALCIUM ION
著者Brejc, K, van Dijk, W.J, Klaassen, R, Schuurmans, M, van der Oost, J, Smit, A.B, Sixma, T.K.
登録日2001-03-18
公開日2001-05-16
最終更新日2018-03-07
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Crystal structure of an ACh-binding protein reveals the ligand-binding domain of nicotinic receptors.
Nature, 411, 2001
5NFV
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BU of 5nfv by Molmil
Crystal structure of catalytically inactive FnCas12 mutant bound to an R-loop structure containing a pre-crRNA mimic and full-length DNA target
分子名称: 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CRISPR-associated endonuclease Cpf1, DNA non-target strand, ...
著者Swarts, D.C, van der Oost, J, Jinek, M.
登録日2017-03-16
公開日2017-06-14
実験手法X-RAY DIFFRACTION (2.501 Å)
主引用文献Structural Basis for Guide RNA Processing and Seed-Dependent DNA Targeting by CRISPR-Cas12a.
Mol. Cell, 66, 2017
3JUR
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BU of 3jur by Molmil
The crystal structure of a hyperthermoactive Exopolygalacturonase from Thermotoga maritima
分子名称: Exo-poly-alpha-D-galacturonosidase
著者Pijning, T, van Pouderoyen, G, Kluskens, L.D, van der Oost, J, Dijkstra, B.W.
登録日2009-09-15
公開日2009-11-17
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献The crystal structure of a hyperthermoactive exopolygalacturonase from Thermotoga maritima reveals a unique tetramer
Febs Lett., 2009
2CG4
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BU of 2cg4 by Molmil
Structure of E.coli AsnC
分子名称: ASPARAGINE, MAGNESIUM ION, REGULATORY PROTEIN ASNC
著者Thaw, P, Sedelnikova, S.E, Muranova, T, Wiese, S, Ayora, S, Alonso, J.C, Brinkman, A.B, Akerboom, J, van der Oost, J, Rafferty, J.B.
登録日2006-02-27
公開日2006-04-04
最終更新日2021-04-28
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural Insight Into Gene Transcriptional Regulation and Effector Binding by the Lrp/Asnc Family.
Nucleic Acids Res., 34, 2006
2HTN
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BU of 2htn by Molmil
E. coli bacterioferritin in its as-isolated form
分子名称: Bacterioferritin, FE (III) ION, PROTOPORPHYRIN IX CONTAINING FE
著者van Eerde, A, Wolterink-Van Loo, S, Van Der Oost, J, Dijkstra, B.W.
登録日2006-07-26
公開日2006-11-21
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Fortuitous structure determination of 'as-isolated' Escherichia coli bacterioferritin in a novel crystal form.
Acta Crystallogr.,Sect.F, 62, 2006
1I1G
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BU of 1i1g by Molmil
CRYSTAL STRUCTURE OF THE LRP-LIKE TRANSCRIPTIONAL REGULATOR FROM THE ARCHAEON PYROCOCCUS FURIOSUS
分子名称: TRANSCRIPTIONAL REGULATOR LRPA
著者Leonard, P.M, Smits, S.H.J, Sedelnikova, S.E, Brinkman, A.B, de Vos, W.M, van der Oost, J, Rice, D.W, Rafferty, J.B.
登録日2001-02-01
公開日2002-02-06
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Crystal structure of the Lrp-like transcriptional regulator from the archaeon Pyrococcus furiosus.
EMBO J., 20, 2001
3DOH
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BU of 3doh by Molmil
Crystal Structure of a Thermostable Esterase
分子名称: SULFATE ION, esterase
著者Levisson, M, Sun, L, Hendriks, S, Dijkstra, B.W, Van der Oost, J, Kengen, S.W.M.
登録日2008-07-04
公開日2009-02-17
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Crystal structure and biochemical properties of a novel thermostable esterase containing an immunoglobulin-like domain.
J.Mol.Biol., 385, 2009
3DOI
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BU of 3doi by Molmil
Crystal Structure of a Thermostable Esterase complex with paraoxon
分子名称: DIETHYL PHOSPHONATE, esterase
著者Levisson, M, Sun, L, Hendriks, S, Dijkstra, B.W, Van der Oost, J, Kengen, S.W.M.
登録日2008-07-04
公開日2009-02-17
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Crystal structure and biochemical properties of a novel thermostable esterase containing an immunoglobulin-like domain.
J.Mol.Biol., 385, 2009
2H6E
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BU of 2h6e by Molmil
Crystal structure of the D-arabinose dehydrogenase from Sulfolobus solfataricus
分子名称: D-arabinose 1-dehydrogenase, ZINC ION
著者Brouns, S.J.J, Turnbull, A.P, Akerboom, J, Willemen, H.L.D.M, De Vos, W.M, Van der Oost, J.
登録日2006-05-31
公開日2007-06-05
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal Structure and Biochemical Properties of the d-Arabinose Dehydrogenase from Sulfolobus solfataricus
J.Mol.Biol., 371, 2007
1X82
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BU of 1x82 by Molmil
CRYSTAL STRUCTURE OF PHOSPHOGLUCOSE ISOMERASE FROM PYROCOCCUS FURIOSUS WITH BOUND 5-phospho-D-arabinonate
分子名称: 5-PHOSPHOARABINONIC ACID, Glucose-6-phosphate isomerase
著者Berrisford, J.M, Akerboom, J, Brouns, S, Sedelnikova, S.E, Turnbull, A.P, van der Oost, J, Salmon, L, Hardre, R, Murray, I.A, Blackburn, G.M, Rice, D.W, Baker, P.J.
登録日2004-08-17
公開日2004-10-12
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献The structures of inhibitor complexes of Pyrococcus furiosus phosphoglucose isomerase provide insights into substrate binding and catalysis.
J.Mol.Biol., 343, 2004
1X7N
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BU of 1x7n by Molmil
The crystal structure of Pyrococcus furiosus phosphoglucose isomerase with bound 5-phospho-D-arabinonate and Manganese
分子名称: 5-PHOSPHOARABINONIC ACID, Glucose-6-phosphate isomerase, MANGANESE (II) ION
著者Berrisford, J.M, Akerboom, J, Brouns, S, Sedelnikova, S.E, Turnbull, A.P, van der Oost, J, Salmon, L, Hardre, R, Murray, I.A, Blackburn, G.M, Rice, D.W, Baker, P.J.
登録日2004-08-16
公開日2004-10-12
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.89 Å)
主引用文献The structures of inhibitor complexes of Pyrococcus furiosus phosphoglucose isomerase provide insights into substrate binding and catalysis.
J.Mol.Biol., 343, 2004
1X8E
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BU of 1x8e by Molmil
Crystal structure of Pyrococcus furiosus phosphoglucose isomerase free enzyme
分子名称: Glucose-6-phosphate isomerase
著者Berrisford, J.M, Akerboom, J, Brouns, S, Sedelnikova, S.E, Turnbull, A.P, van der Oost, J, Salmon, L, Hardre, R, Murray, I.A, Blackburn, G.M, Rice, D.W, Baker, P.J.
登録日2004-08-18
公開日2004-10-12
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献The structures of inhibitor complexes of Pyrococcus furiosus phosphoglucose isomerase provide insights into substrate binding and catalysis.
J.Mol.Biol., 343, 2004
1XRK
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BU of 1xrk by Molmil
Crystal structure of a mutant bleomycin binding protein from Streptoalloteichus hindustanus displaying increased thermostability
分子名称: BLEOMYCIN A2, Bleomycin resistance protein, SULFATE ION
著者Brouns, S.J.J, Wu, H, Akerboom, J, Turnbull, A.P, de Vos, W.M, Van der Oost, J.
登録日2004-10-15
公開日2005-01-11
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Engineering a selectable marker for hyperthermophiles
J.Biol.Chem., 280, 2005
4Q2C
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BU of 4q2c by Molmil
Crystal structure of CRISPR-associated protein
分子名称: CRISPR-associated helicase Cas3, NICKEL (II) ION
著者Gong, B, Shin, M, Sun, J, van der Oost, J, Kim, J.-S.
登録日2014-04-07
公開日2014-11-19
最終更新日2022-08-24
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Molecular insights into DNA interference by CRISPR-associated nuclease-helicase Cas3.
Proc.Natl.Acad.Sci.USA, 111, 2014
4Q2D
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BU of 4q2d by Molmil
Crystal Structure of CRISPR-Associated protein in complex with 2'-Deoxyadenosine 5'-Triphosphate
分子名称: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CRISPR-associated helicase Cas3, MAGNESIUM ION, ...
著者Gong, B, Shin, M, Sun, J, van der Oost, J, Kim, J.-S.
登録日2014-04-07
公開日2014-11-19
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (2.771 Å)
主引用文献Molecular insights into DNA interference by CRISPR-associated nuclease-helicase Cas3.
Proc.Natl.Acad.Sci.USA, 111, 2014
2QTF
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BU of 2qtf by Molmil
Crystal structure of a GTP-binding protein from the hyperthermophilic archaeon Sulfolobus solfataricus
分子名称: ACETATE ION, CADMIUM ION, GTP-binding protein, ...
著者Wu, H, Sun, L, Brouns, S.J, Fu, S, Rao, Z, Van der Oost, J.
登録日2007-08-02
公開日2008-08-19
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structure of a GTP-binding protein from the hyperthermophilic archaeon Sulfolobus solfataricus.
To be Published
2QTH
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BU of 2qth by Molmil
Crystal structure of a GTP-binding protein from the hyperthermophilic archaeon Sulfolobus solfataricus in complex with GDP
分子名称: ACETATE ION, CADMIUM ION, GTP-binding protein, ...
著者Wu, H, Sun, L, Brouns, S.J, Fu, S, Rao, Z, Van der Oost, J.
登録日2007-08-02
公開日2008-08-19
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structure of a GTP-binding protein from the hyperthermophilic archaeon Sulfolobus solfataricus.
To be Published
2TMG
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BU of 2tmg by Molmil
THERMOTOGA MARITIMA GLUTAMATE DEHYDROGENASE MUTANT S128R, T158E, N117R, S160E
分子名称: PROTEIN (GLUTAMATE DEHYDROGENASE)
著者Knapp, S, Lebbink, J.H.G, van der Oost, J, de Vos, W.M, Rice, D, Ladenstein, R.
登録日1998-12-04
公開日1999-12-08
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Engineering activity and stability of Thermotoga maritima glutamate dehydrogenase. II: construction of a 16-residue ion-pair network at the subunit interface.
J.Mol.Biol., 289, 1999
1R6V
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BU of 1r6v by Molmil
Crystal structure of fervidolysin from Fervidobacterium pennivorans, a keratinolytic enzyme related to subtilisin
分子名称: CALCIUM ION, subtilisin-like serine protease
著者Kim, J.S, Kluskens, L.D, de Vos, W.M, Huber, R, van der Oost, J.
登録日2003-10-17
公開日2004-10-19
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Crystal structure of fervidolysin from Fervidobacterium pennivorans, a keratinolytic enzyme related to subtilisin.
J.Mol.Biol., 335, 2004
1S4E
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BU of 1s4e by Molmil
Pyrococcus furiosus galactokinase in complex with galactose, ADP and magnesium
分子名称: ADENOSINE-5'-DIPHOSPHATE, Galactokinase, MAGNESIUM ION, ...
著者Hartley, A, Glynn, S.E, Barynin, V, Baker, P.J, Sedelnikova, S.E, Verhees, C, de Geus, D, van der Oost, J, Timson, D.J, Reece, R.J, Rice, D.W.
登録日2004-01-16
公開日2004-04-06
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Substrate specificity and mechanism from the structure of Pyrococcus furiosus galactokinase
J.Mol.Biol., 337, 2004
8HHM
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BU of 8hhm by Molmil
Cryo-EM structure of the Cas12m2-crRNA-target DNA ternary complex intermediate state
分子名称: Cas12m2, DNA (36-MER), GUANOSINE-5'-MONOPHOSPHATE, ...
著者Omura, N.S, Nakagawa, R, Wu, Y.W, Sudfeld, C, Warren, V.R, Hirano, H, Kusakizako, T, Kise, Y, Lebbink, H.G.J, Itoh, Y, Oost, V.D.J, Nureki, O.
登録日2022-11-16
公開日2023-04-12
最終更新日2023-08-30
実験手法ELECTRON MICROSCOPY (3.08 Å)
主引用文献Mechanistic and evolutionary insights into a type V-M CRISPR-Cas effector enzyme.
Nat.Struct.Mol.Biol., 30, 2023

 

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