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6DKF
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BU of 6dkf by Molmil
Caseinolytic protease (ClpP) from Staphylococcus aureus mutant - V7A
Descriptor: ATP-dependent Clp protease proteolytic subunit
Authors:Ripstein, Z.A, Vahidi, S, Kay, L.E, Rubinstein, J.L.
Deposit date:2018-05-29
Release date:2018-06-27
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Reversible inhibition of the ClpP protease via an N-terminal conformational switch.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6VGQ
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BU of 6vgq by Molmil
ClpP1P2 complex from M. tuberculosis with GLF-CMK bound to ClpP1
Descriptor: ATP-dependent Clp protease proteolytic subunit, ATP-dependent Clp protease proteolytic subunit 1, Z-Gly-leu-phe-CH2Cl
Authors:Ripstein, Z.A, Vahidi, S, Rubinstein, J.L, Kay, L.E.
Deposit date:2020-01-08
Release date:2020-03-18
Last modified:2020-04-01
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:An allosteric switch regulatesMycobacterium tuberculosisClpP1P2 protease function as established by cryo-EM and methyl-TROSY NMR.
Proc.Natl.Acad.Sci.USA, 117, 2020
6VGK
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BU of 6vgk by Molmil
ClpP1P2 complex from M. tuberculosis
Descriptor: ATP-dependent Clp protease proteolytic subunit 1, ATP-dependent Clp protease proteolytic subunit 2
Authors:Ripstein, Z.A, Vahidi, S, Rubinstein, J.L, Kay, L.E.
Deposit date:2020-01-08
Release date:2020-03-18
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:An allosteric switch regulatesMycobacterium tuberculosisClpP1P2 protease function as established by cryo-EM and methyl-TROSY NMR.
Proc.Natl.Acad.Sci.USA, 117, 2020
6VGN
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BU of 6vgn by Molmil
ClpP1P2 complex from M. tuberculosis bound to ADEP
Descriptor: ATP-dependent Clp protease proteolytic subunit, ATP-dependent Clp protease proteolytic subunit 1, R0M-WFP-ALO-PRO-YCP-ALA-MP8
Authors:Ripstein, Z.A, Vahidi, S, Rubinstein, J.L, Kay, L.E.
Deposit date:2020-01-08
Release date:2020-03-18
Last modified:2020-04-01
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:An allosteric switch regulatesMycobacterium tuberculosisClpP1P2 protease function as established by cryo-EM and methyl-TROSY NMR.
Proc.Natl.Acad.Sci.USA, 117, 2020
7KR2
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BU of 7kr2 by Molmil
ClpP from Neisseria meningitidis - Compressed conformation
Descriptor: ATP-dependent Clp protease proteolytic subunit
Authors:Ripstein, Z.A, Vahidi, S, Rubinstein, J.L, Kay, L.E.
Deposit date:2020-11-18
Release date:2021-11-24
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:A pH-Dependent Conformational Switch Controls N. meningitidis ClpP Protease Function
To Be Published
6VFX
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BU of 6vfx by Molmil
ClpXP from Neisseria meningitidis - Conformation B
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP-dependent Clp protease ATP-binding subunit ClpX, ...
Authors:Ripstein, Z.A, Vahidi, S, Houry, W.A, Rubinstein, J.L, Kay, L.E.
Deposit date:2020-01-06
Release date:2020-01-22
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:A processive rotary mechanism couples substrate unfolding and proteolysis in the ClpXP degradation machinery.
Elife, 9, 2020
6VFS
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BU of 6vfs by Molmil
ClpXP from Neisseria meningitidis - Conformation A
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP-dependent Clp protease ATP-binding subunit ClpX, ...
Authors:Ripstein, Z.A, Vahidi, S, Houry, W.A, Rubinstein, J.L, Kay, L.E.
Deposit date:2020-01-06
Release date:2020-01-22
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:A processive rotary mechanism couples substrate unfolding and proteolysis in the ClpXP degradation machinery.
Elife, 9, 2020
8E9H
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BU of 8e9h by Molmil
Mycobacterial respiratory complex I, fully-inserted quinone
Descriptor: (2R)-3-{[(R)-hydroxy({(1S,2R,3R,4R,5S,6S)-3,4,5-trihydroxy-2-(alpha-D-mannopyranosyloxy)-6-[(6-O-undecanoyl-beta-D-mannopyranosyl)oxy]cyclohexyl}oxy)phosphoryl]oxy}-2-(octanoyloxy)propyl undecanoate, FE2/S2 (INORGANIC) CLUSTER, FLAVIN MONONUCLEOTIDE, ...
Authors:Liang, Y, Rubinstein, J.L.
Deposit date:2022-08-26
Release date:2022-10-12
Last modified:2023-04-05
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:Structure of mycobacterial respiratory complex I.
Proc.Natl.Acad.Sci.USA, 120, 2023
8E9G
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BU of 8e9g by Molmil
Mycobacterial respiratory complex I with both quinone positions modelled
Descriptor: (2R)-3-{[(R)-hydroxy({(1S,2R,3R,4R,5S,6S)-3,4,5-trihydroxy-2-(alpha-D-mannopyranosyloxy)-6-[(6-O-undecanoyl-beta-D-mannopyranosyl)oxy]cyclohexyl}oxy)phosphoryl]oxy}-2-(octanoyloxy)propyl undecanoate, FE2/S2 (INORGANIC) CLUSTER, FLAVIN MONONUCLEOTIDE, ...
Authors:Liang, Y, Rubinstein, J.L.
Deposit date:2022-08-26
Release date:2022-10-12
Last modified:2023-04-05
Method:ELECTRON MICROSCOPY (2.6 Å)
Cite:Structure of mycobacterial respiratory complex I.
Proc.Natl.Acad.Sci.USA, 120, 2023
8E9I
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BU of 8e9i by Molmil
Mycobacterial respiratory complex I, semi-inserted quinone
Descriptor: (2R)-3-{[(R)-hydroxy({(1S,2R,3R,4R,5S,6S)-3,4,5-trihydroxy-2-(alpha-D-mannopyranosyloxy)-6-[(6-O-undecanoyl-beta-D-mannopyranosyl)oxy]cyclohexyl}oxy)phosphoryl]oxy}-2-(octanoyloxy)propyl undecanoate, FE2/S2 (INORGANIC) CLUSTER, FLAVIN MONONUCLEOTIDE, ...
Authors:Liang, Y, Rubinstein, J.L.
Deposit date:2022-08-26
Release date:2022-10-12
Last modified:2023-04-05
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Structure of mycobacterial respiratory complex I.
Proc.Natl.Acad.Sci.USA, 120, 2023
6NB1
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BU of 6nb1 by Molmil
Crystal structure of Escherichia coli ClpP protease complexed with small molecule activator, ACP1-06
Descriptor: ATP-dependent Clp protease proteolytic subunit, GLYCEROL, N-{2-[(2-chlorophenyl)sulfanyl]ethyl}-2-methyl-2-{[5-(trifluoromethyl)pyridin-2-yl]sulfonyl}propanamide
Authors:Mabanglo, M.F, Houry, W.A, Eger, B.T, Bryson, S, Pai, E.F.
Deposit date:2018-12-06
Release date:2019-11-13
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:ClpP protease activation results from the reorganization of the electrostatic interaction networks at the entrance pores.
Commun Biol, 2, 2019
6NAQ
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BU of 6naq by Molmil
Crystal structure of Neisseria meningitidis ClpP protease in Apo form
Descriptor: ATP-dependent Clp protease proteolytic subunit, POTASSIUM ION
Authors:Houry, W.A, Mabanglo, M.F, Pai, E.F, Eger, B.T, Bryson, S.
Deposit date:2018-12-06
Release date:2019-11-13
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.022 Å)
Cite:ClpP protease activation results from the reorganization of the electrostatic interaction networks at the entrance pores.
Commun Biol, 2, 2019
6NAY
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BU of 6nay by Molmil
Crystal structure of Neisseria meningitidis ClpP protease E31A+E58A activated double mutant
Descriptor: ATP-dependent Clp protease proteolytic subunit
Authors:Mabanglo, M.F, Houry, W.A.
Deposit date:2018-12-06
Release date:2019-11-13
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.199 Å)
Cite:ClpP protease activation results from the reorganization of the electrostatic interaction networks at the entrance pores.
Commun Biol, 2, 2019
6NAH
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BU of 6nah by Molmil
Crystal structure of Neisseria meningitidis ClpP protease in complex with Acyldepsipeptide-14 (ADEP-14)
Descriptor: ATP-dependent Clp protease proteolytic subunit, Acyldepsipeptide-14, OCTANOIC ACID (CAPRYLIC ACID)
Authors:Mabanglo, M.F, Houry, W.A.
Deposit date:2018-12-05
Release date:2019-11-13
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:ClpP protease activation results from the reorganization of the electrostatic interaction networks at the entrance pores.
Commun Biol, 2, 2019
6NAW
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BU of 6naw by Molmil
Crystal structure of Neisseria meningitidis ClpP E58A activated mutant
Descriptor: ATP-dependent Clp protease proteolytic subunit
Authors:Mabanglo, M.F, Houry, W.A.
Deposit date:2018-12-06
Release date:2019-11-13
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.399 Å)
Cite:ClpP protease activation results from the reorganization of the electrostatic interaction networks at the entrance pores.
Commun Biol, 2, 2019
8SNH
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BU of 8snh by Molmil
cytochrome bc1-cbb3 supercomplex from Pseudomonas aeruginosa
Descriptor: (2R)-2-(methoxymethyl)-4-{[(25R)-spirost-5-en-3beta-yl]oxy}butyl 4-O-alpha-D-glucopyranosyl-beta-D-glucopyranoside, CALCIUM ION, COPPER (II) ION, ...
Authors:Di Trani, J.M, Rubinstein, J.L.
Deposit date:2023-04-27
Release date:2023-10-11
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:Structure of the bc 1 - cbb 3 respiratory supercomplex from Pseudomonas aeruginosa.
Proc.Natl.Acad.Sci.USA, 120, 2023
8SMR
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BU of 8smr by Molmil
cytochrome bc1-cbb3 supercomplex from Pseudomonas aeruginosa
Descriptor: (2R)-2-(methoxymethyl)-4-{[(25R)-spirost-5-en-3beta-yl]oxy}butyl 4-O-alpha-D-glucopyranosyl-beta-D-glucopyranoside, CALCIUM ION, COPPER (II) ION, ...
Authors:Di Trani, J.M, Rubinstein, J.L.
Deposit date:2023-04-26
Release date:2023-10-11
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:Structure of the bc 1 - cbb 3 respiratory supercomplex from Pseudomonas aeruginosa.
Proc.Natl.Acad.Sci.USA, 120, 2023

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