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6NI3
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BU of 6ni3 by Molmil
B2V2R-Gs protein subcomplex of a GPCR-G protein-beta-arrestin mega-complex
Descriptor: 8-[(1R)-2-{[1,1-dimethyl-2-(2-methylphenyl)ethyl]amino}-1-hydroxyethyl]-5-hydroxy-2H-1,4-benzoxazin-3(4H)-one, Endolysin,Beta-2 adrenergic receptor chimera, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
Authors:Nguyen, A.H, Thomsen, A.R.B, Cahill, T.J, des Georges, A, Lefkowitz, R.J.
Deposit date:2018-12-26
Release date:2019-11-20
Last modified:2024-10-16
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Structure of an endosomal signaling GPCR-G protein-beta-arrestin megacomplex.
Nat.Struct.Mol.Biol., 26, 2019
6NI2
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BU of 6ni2 by Molmil
Stabilized beta-arrestin 1-V2T subcomplex of a GPCR-G protein-beta-arrestin mega-complex
Descriptor: Beta-arrestin-1, Fab30 Heavy Chain, Fab30 Light Chain, ...
Authors:Nguyen, A.H, Thomsen, A.R.B, Cahill, T.J, des Georges, A, Lefkowitz, R.J.
Deposit date:2018-12-26
Release date:2019-11-20
Last modified:2024-11-20
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Structure of an endosomal signaling GPCR-G protein-beta-arrestin megacomplex.
Nat.Struct.Mol.Biol., 26, 2019
9DNG
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BU of 9dng by Molmil
Structure of rat beta-arrestin 1 by fiducial-assisted cryo-EM
Descriptor: Beta-arrestin-1,Soluble cytochrome b562, anti-BRIL Fab Heavy chain, anti-BRIL Fab LIGHT chain
Authors:Pakharukova, N, Kahsai, A.W, Masoudi, A, Lefkowitz, R.J.
Deposit date:2024-09-17
Release date:2025-01-22
Method:ELECTRON MICROSCOPY (3.52 Å)
Cite:Small Molecule Modulators of beta-arrestins.
Biorxiv, 2024
9DNM
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BU of 9dnm by Molmil
Structure of rat beta-arrestin 1 bound to allosteric inhibitor
Descriptor: (1beta,6beta,7beta,8alpha,9beta,10alpha,13alpha,14R,16beta)-1,6,7,14-tetrahydroxy-7,20-epoxykauran-15-one, Beta-arrestin-1,Soluble cytochrome b562, anti-BRIL Fab Heavy chain, ...
Authors:Pakharukova, N, Kahsai, A.W, Masoudi, A, Lefkowitz, R.J.
Deposit date:2024-09-17
Release date:2025-01-22
Method:ELECTRON MICROSCOPY (3.47 Å)
Cite:Small Molecule Modulators of beta-arrestins.
Biorxiv, 2024

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PDB entries from 2025-06-04

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