6ES4
| A cryptic RNA-binding domain mediates Syncrip recognition and exosomal partitioning of miRNA targets | 分子名称: | 1,2-ETHANEDIOL, SULFATE ION, Syncrip, ... | 著者 | Hobor, F, Dallmann, A, Ball, N.J, Cicchini, C, Battistelli, C, Ogrodowicz, R.W, Christodoulou, E, Martin, S.R, Castello, A, Tripodi, M, Taylor, I.A, Ramos, A. | 登録日 | 2017-10-19 | 公開日 | 2018-03-07 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | A cryptic RNA-binding domain mediates Syncrip recognition and exosomal partitioning of miRNA targets. Nat Commun, 9, 2018
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5Z1V
| Crystal structure of AvrPib | 分子名称: | AvrPib protein | 著者 | Zhang, X, He, D, Zhao, Y.X, Taylor, I.A, Peng, Y.L, Yang, J, Liu, J.F. | 登録日 | 2017-12-28 | 公開日 | 2018-09-05 | 最終更新日 | 2018-10-03 | 実験手法 | X-RAY DIFFRACTION (1.661 Å) | 主引用文献 | A positive-charged patch and stabilized hydrophobic core are essential for avirulence function of AvrPib in the rice blast fungus. Plant J., 96, 2018
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2V4X
| Crystal Structure of Jaagsiekte Sheep Retrovirus Capsid N-terminal domain | 分子名称: | CAPSID PROTEIN P27 | 著者 | Mortuza, G.B, Goldstone, D.C, Pashley, C, Haire, L.F, Palmarini, M, Taylor, W.R, Stoye, J.P, Taylor, I.A. | 登録日 | 2008-09-30 | 公開日 | 2008-11-25 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Structure of the Capsid Amino-Terminal Domain from the Betaretrovirus, Jaagsiekte Sheep Retrovirus. J.Mol.Biol., 386, 2009
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6XU1
| Crystal structure of tetrameric human H215A-SAMHD1 (residues 109-626) with GTP, dAMPNPP and Mg | 分子名称: | 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]adenosine, Deoxynucleoside triphosphate triphosphohydrolase SAMHD1, FE (III) ION, ... | 著者 | Morris, E.R, Kunzelmann, S, Caswell, S.J, Arnold, L.H, Purkiss, A.G, Kelly, G, Taylor, I.A. | 登録日 | 2020-01-17 | 公開日 | 2020-06-24 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Crystal structures of SAMHD1 inhibitor complexes reveal the mechanism of water-mediated dNTP hydrolysis. Nat Commun, 11, 2020
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6YOM
| Crystal structure of tetrameric human D137N-SAMHD1 (residues 109-626) with XTP, dATP, dCMPNPP, Mn and Mg | 分子名称: | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]cytidine, Deoxynucleoside triphosphate triphosphohydrolase SAMHD1, ... | 著者 | Morris, E.R, Kunzelmann, S, Caswell, S.J, Arnold, L.H, Purkiss, A.G, Kelly, G, Taylor, I.A. | 登録日 | 2020-04-14 | 公開日 | 2020-06-24 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (3.25 Å) | 主引用文献 | Crystal structures of SAMHD1 inhibitor complexes reveal the mechanism of water-mediated dNTP hydrolysis. Nat Commun, 11, 2020
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7NLH
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7NLI
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7NLG
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2NPI
| Clp1-ATP-Pcf11 complex | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Protein CLP1, ... | 著者 | Noble, C.G, Beuth, B, Taylor, I.A. | 登録日 | 2006-10-27 | 公開日 | 2006-12-19 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | 主引用文献 | Structure of a nucleotide-bound Clp1-Pcf11 polyadenylation factor Nucleic Acids Res., 35, 2007
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8COO
| Solution structure of Zipcode binding protein 1 (ZBP1) KH3(DD)KH4 domains in complex with N6-Methyladenosine containing RNA | 分子名称: | Insulin-like growth factor 2 mRNA-binding protein 1, RNA_(5'-R(*(UP*CP*GP*GP*(6MZ)P*CP*U)-3') | 著者 | Nicastro, G, Abis, G, Taylor, I.A, Ramos, A. | 登録日 | 2023-02-28 | 公開日 | 2024-02-07 | 実験手法 | SOLUTION NMR | 主引用文献 | Direct m6A recognition by IMP1 underlays an alternative model of target selection for non-canonical methyl-readers. Nucleic Acids Res., 51, 2023
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2X1A
| Structure of Rna15 RRM with RNA bound (G) | 分子名称: | 5'-R(*GP*UP*UP*GP*UP)-3', MAGNESIUM ION, MRNA 3'-END-PROCESSING PROTEIN RNA15 | 著者 | Pancevac, C, Goldstone, D.C, Ramos, A, Taylor, I.A. | 登録日 | 2010-01-06 | 公開日 | 2010-02-02 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | Structure of the RNA15 Rrm-RNA Complex Reveals the Molecular Basis of Gu Specificity in Transcriptional 3-End Processing Factors. Nucleic Acids Res., 38, 2010
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2X1F
| Structure of Rna15 RRM with bound RNA (GU) | 分子名称: | 5'-R(*GP*UP*UP*GP*UP)-3', MRNA 3'-END-PROCESSING PROTEIN RNA15 | 著者 | Pancevac, C, Goldstone, D.C, Ramos, A, Taylor, I.A. | 登録日 | 2010-01-06 | 公開日 | 2010-02-02 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Structure of the RNA15 Rrm-RNA Complex Reveals the Molecular Basis of Gu Specificity in Transcriptional 3-End Processing Factors. Nucleic Acids Res., 38, 2010
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2Y4Z
| Structure of the amino-terminal capsid restriction escape mutation N- MLV L10W | 分子名称: | CAPSID PROTEIN P30, GLYCEROL | 著者 | Goldstone, D.C, Holden-Dye, K, Ohkura, S, Stoye, J.P, Taylor, I.A. | 登録日 | 2011-01-11 | 公開日 | 2011-11-23 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.001 Å) | 主引用文献 | Novel Escape Mutants Suggest an Extensive Trim5Alpha Binding Site Spanning the Entire Outer Surface of the Murine Leukemia Virus Capsid Protein. Plos Pathog., 7, 2011
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1G6G
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3BP9
| Structure of B-tropic MLV capsid N-terminal domain | 分子名称: | GLYCEROL, Gag protein, ISOPROPYL ALCOHOL | 著者 | Gulnahar, M.B, Dodding, M.P, Goldstone, D.C, Haire, L.F, Stoye, J.P, Taylor, I.A. | 登録日 | 2007-12-18 | 公開日 | 2008-02-12 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Structure of B-MLV capsid amino-terminal domain reveals key features of viral tropism, gag assembly and core formation J.Mol.Biol., 376, 2008
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5AJA
| Crystal structure of mandrill SAMHD1 (amino acid residues 1-114) bound to Vpx isolated from mandrill and human DCAF1 (amino acid residues 1058-1396) | 分子名称: | PROTEIN VPRBP, SAM DOMAIN AND HD DOMAIN-CONTAINING PROTEIN, VPX PROTEIN, ... | 著者 | Schwefel, D, Boucherit, V.C, Christodoulou, E, Walker, P.A, Stoye, J.P, Bishop, K.N, Taylor, I.A. | 登録日 | 2015-02-20 | 公開日 | 2015-04-22 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.649 Å) | 主引用文献 | Molecular Determinants for Recognition of Divergent Samhd1 Proteins by the Lentiviral Accessory Protein Vpx. Cell Host Microbe., 17, 2015
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5AO1
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5AO0
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5AO2
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5AO3
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5AO4
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2ASB
| Structure of a Mycobacterium tuberculosis NusA-RNA complex | 分子名称: | Transcription elongation protein nusA, ribosomal RNA (5'- GAACUCAAUAG -3') | 著者 | Beuth, B, Pennell, S, Arnvig, K.B, Martin, S.R, Taylor, I.A. | 登録日 | 2005-08-23 | 公開日 | 2005-10-11 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Structure of a Mycobacterium tuberculosis NusA-RNA complex. Embo J., 24, 2005
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2ATW
| Structure of a Mycobacterium tuberculosis NusA-RNA complex | 分子名称: | Transcription elongation protein nusA, ribosomal RNA (5'- AGAACUCAAUAG -3') | 著者 | Beuth, B, Pennell, S, Arnvig, K.B, Martin, S.R, Taylor, I.A. | 登録日 | 2005-08-26 | 公開日 | 2005-10-11 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | Structure of a Mycobacterium tuberculosis NusA-RNA complex. Embo J., 24, 2005
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2BF0
| crystal structure of the rpr of pcf11 | 分子名称: | CALCIUM ION, PCF11 | 著者 | Noble, C.G, Hollingworth, D, Martin, S.R, Adeniran, V.E, Smerdon, S.J, Kelly, G, Taylor, I.A, Ramos, A. | 登録日 | 2004-12-02 | 公開日 | 2005-01-18 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Key Features of the Interaction between Pcf11 Cid and RNA Polymerase II Ctd. Nat.Struct.Mol.Biol., 12, 2005
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6SSJ
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