5GJE
| Three-dimensional reconstruction of human LRP6 ectodomain complexed with Dkk1 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Matoba, K, Mihara, E, Tamura-Kawakami, K, Hirai, H, Thompson, S, Iwasaki, K, Takagi, J. | Deposit date: | 2016-06-29 | Release date: | 2017-01-18 | Last modified: | 2020-07-29 | Method: | ELECTRON MICROSCOPY (21 Å) | Cite: | Conformational Freedom of the LRP6 Ectodomain Is Regulated by N-glycosylation and the Binding of the Wnt Antagonist Dkk1 Cell Rep, 18, 2017
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4YNY
| Crystal structure of monoclonal anti-human podoplanin antibody NZ-1 | Descriptor: | Heavy chain of antigen binding fragment, Fab, Light chain of antigen binding fragment | Authors: | Fujii, Y, Kitago, Y, Arimori, T, Takagi, J. | Deposit date: | 2015-03-11 | Release date: | 2016-03-02 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.584 Å) | Cite: | Tailored placement of a turn-forming PA tag into the structured domain of a protein to probe its conformational state J.Cell.Sci., 129, 2016
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5B4Y
| Crystal structure of the LA12 fragment of ApoER2 | Descriptor: | CALCIUM ION, Low-density lipoprotein receptor-related protein 8 | Authors: | Nogi, T, Tabata, S, Hirai, H, Yasui, N, Takagi, J. | Deposit date: | 2016-04-20 | Release date: | 2017-04-26 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystal structure of the ectodomain from a LDLR close homologue in complex with its physiological ligand. To Be Published
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5AUM
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5B4W
| Crystal structure of Plexin inhibitor complex | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Plexin-B1, Synthesized cyclic peptide | Authors: | Matsunaga, Y, Kitago, Y, Arimori, T, Takagi, J. | Deposit date: | 2016-04-19 | Release date: | 2016-12-28 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Allosteric Inhibition of a Semaphorin 4D Receptor Plexin B1 by a High-Affinity Macrocyclic Peptide Cell Chem Biol, 23, 2016
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5B4X
| Crystal structure of the ApoER2 ectodomain in complex with the Reelin R56 fragment | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Low density lipoprotein receptor-related protein 8, ... | Authors: | Yasui, N, Hirai, H, Yamashita, K, Takagi, J, Nogi, T. | Deposit date: | 2016-04-20 | Release date: | 2017-04-26 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Crystal structure of the ectodomain from a LDLR close homologue in complex with its physiological ligand. To Be Published
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2DDU
| Crystal structure of the third repeat domain of reelin | Descriptor: | CALCIUM ION, CHLORIDE ION, MAGNESIUM ION, ... | Authors: | Nogi, T, Yasui, N, Takagi, J. | Deposit date: | 2006-02-03 | Release date: | 2006-09-26 | Last modified: | 2011-10-05 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Structure of a signaling-competent reelin fragment revealed by X-ray crystallography and electron tomography Embo J., 25, 2006
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6LZ9
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7VF3
| Plexin B1 extracellular fragment in complex with lasso-grafted PB1m7 peptide | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, DI(HYDROXYETHYL)ETHER, Plexin-B1, ... | Authors: | Sugano, N.N, Hirata, K, Yamashita, K, Yamamoto, M, Arimori, T, Takagi, J. | Deposit date: | 2021-09-10 | Release date: | 2022-08-17 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.29 Å) | Cite: | De novo Fc-based receptor dimerizers differentially modulate PlexinB1 function. Structure, 30, 2022
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7XOL
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7XOS
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7XOQ
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7XOK
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7XOP
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7XON
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7XOM
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7XOR
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7XOJ
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7XOO
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1L3Y
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1MQ8
| Crystal structure of alphaL I domain in complex with ICAM-1 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Integrin alpha-L, ... | Authors: | Shimaoka, M, Xiao, T, Liu, J.-H, Yang, Y, Dong, Y, Jun, C.-D, McCormack, A, Zhang, R, Joachimiak, A, Takagi, J, Wang, J.-H, Springer, T.A. | Deposit date: | 2002-09-15 | Release date: | 2003-01-14 | Last modified: | 2021-10-27 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | Structures of the aL I domain and its complex with ICAM-1 reveal a shape-shifting pathway for integrin regulation Cell(Cambridge,Mass.), 112, 2003
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1MQA
| Crystal structure of high affinity alphaL I domain in the absence of ligand or metal | Descriptor: | Integrin alpha-L | Authors: | Shimaoka, T, Xiao, T, Liu, J.-H, Yang, Y, Dong, Y, Jun, C.-D, Zhang, R, Takagi, J, Wang, J.-H, Springer, T.A. | Deposit date: | 2002-09-15 | Release date: | 2003-01-14 | Last modified: | 2021-10-27 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structures of the aL I domain and its complex with ICAM-1 reveal a shape-shifting pathway for integrin regulation Cell(Cambridge,Mass.), 112, 2003
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1MQ9
| Crystal structure of high affinity alphaL I domain with ligand mimetic crystal contact | Descriptor: | Integrin alpha-L, MANGANESE (II) ION | Authors: | Shimaoka, M, Xiao, T, Liu, J.-H, Yang, Y, Dong, Y, Jun, C.-D, McCormack, A, Zhang, R, Joachimiak, A, Takagi, J, Wang, J.-H, Springer, T.A. | Deposit date: | 2002-09-15 | Release date: | 2003-01-14 | Last modified: | 2021-10-27 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structures of the aL I domain and its complex with ICAM-1 reveal a shape-shifting pathway for integrin regulation Cell(Cambridge,Mass.), 112, 2003
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2E26
| Crystal structure of two repeat fragment of reelin | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, ... | Authors: | Yasui, N, Nogi, T, Kitao, T, Takagi, J. | Deposit date: | 2006-11-08 | Release date: | 2007-05-22 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structure of a receptor-binding fragment of reelin and mutational analysis reveal a recognition mechanism similar to endocytic receptors. Proc.Natl.Acad.Sci.Usa, 104, 2007
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1IJQ
| Crystal Structure of the LDL Receptor YWTD-EGF Domain Pair | Descriptor: | LOW-DENSITY LIPOPROTEIN RECEPTOR | Authors: | Jeon, H, Meng, W, Takagi, J, Eck, M.J, Springer, T.A, Blacklow, S.C. | Deposit date: | 2001-04-27 | Release date: | 2001-05-23 | Last modified: | 2018-04-04 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Implications for familial hypercholesterolemia from the structure of the LDL receptor YWTD-EGF domain pair. Nat.Struct.Biol., 8, 2001
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