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8UDZ
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BU of 8udz by Molmil
The Structure of LTBP-49247 Fab Bound to TGFbeta1 Small Latent Complex
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, LTBP-49247 Fab Heavy Chain, LTBP-49247 Fab Light Chain, ...
Authors:Streich Jr, F.C, Nicholls, S.B, Boston, C.J, Ramachandran, S.
Deposit date:2023-09-29
Release date:2024-07-17
Method:X-RAY DIFFRACTION (2.21 Å)
Cite:An antibody that inhibits TGF-beta 1 release from latent extracellular matrix complexes attenuates the progression of renal fibrosis.
Sci.Signal., 17, 2024
6UMX
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BU of 6umx by Molmil
Structural basis for specific inhibition of extracellular activation of pro/latent myostatin by SRK-015
Descriptor: GL29H4-16 Fab Heavy Chain,GL29H4-16 Fab Heavy Chain, GL29H4-16 Fab Light Chain,GL29H4-16 Fab Light Chain, GLYCEROL, ...
Authors:Dagbay, K.B, Treece, E, Streich Jr, F.C, Jackson, J.W, Faucette, R.R, Nikiforov, A, Lin, S.C, Bostion, C.J, Nicholls, S.B, Capili, A.D, Carven, G.J.
Deposit date:2019-10-10
Release date:2020-02-26
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.79 Å)
Cite:Structural basis of specific inhibition of extracellular activation of pro- or latent myostatin by the monoclonal antibody SRK-015.
J.Biol.Chem., 295, 2020
5JNE
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BU of 5jne by Molmil
E2-SUMO-Siz1 E3-SUMO-PCNA complex
Descriptor: E3 SUMO-protein ligase SIZ1,Ubiquitin-like protein SMT3, GLYCEROL, Proliferating cell nuclear antigen, ...
Authors:Lima, C.D, Streich Jr, F.C.
Deposit date:2016-04-29
Release date:2016-08-10
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Capturing a substrate in an activated RING E3/E2-SUMO complex.
Nature, 536, 2016

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PDB entries from 2024-07-17

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