1IAP
 
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3CX8
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3CX7
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3CX6
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1BOF
 | | GI-ALPHA-1 BOUND TO GDP AND MAGNESIUM | | 分子名称: | GI ALPHA 1, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | | 著者 | Coleman, D.E, Sprang, S.R. | | 登録日 | 1998-08-04 | | 公開日 | 1999-01-06 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Crystal structures of the G protein Gi alpha 1 complexed with GDP and Mg2+: a crystallographic titration experiment.
Biochemistry, 37, 1998
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6AU4
 | | Crystal structure of the major quadruplex formed in the human c-MYC promoter | | 分子名称: | DNA (5'-D(*TP*GP*AP*GP*GP*GP*TP*GP*GP*GP*TP*AP*GP*GP*GP*TP*GP*GP*GP*TP*AP*A)-3'), POTASSIUM ION | | 著者 | Stump, S, Mou, T.C, Sprang, S.R, Natale, N.R, Beall, H.D. | | 登録日 | 2017-08-30 | | 公開日 | 2018-09-12 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | | 主引用文献 | Crystal structure of the major quadruplex formed in the promoter region of the human c-MYC oncogene.
PLoS ONE, 13, 2018
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1IK7
 | | Crystal Structure of the Uncomplexed Pelle Death Domain | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, PROBABLE SERINE/THREONINE-PROTEIN KINASE Pelle | | 著者 | Xiao, T, Gardner, K.H, Sprang, S.R. | | 登録日 | 2001-05-02 | | 公開日 | 2002-07-31 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Cosolvent-induced transformation
of a death domain tertiary structure
Proc.Natl.Acad.Sci.USA, 99, 2002
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1BH2
 | | A326S MUTANT OF AN INHIBITORY ALPHA SUBUNIT | | 分子名称: | 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, GUANINE NUCLEOTIDE-BINDING PROTEIN, MAGNESIUM ION | | 著者 | Mixon, M.B, Posner, B.A, Wall, M.A, Gilman, A.G, Sprang, S.R. | | 登録日 | 1998-06-12 | | 公開日 | 1998-11-04 | | 最終更新日 | 2023-08-02 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | The A326S mutant of Gialpha1 as an approximation of the receptor-bound state.
J.Biol.Chem., 273, 1998
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1AS2
 | | GDP+PI BOUND G42V GIA1 | | 分子名称: | GIA1, GUANOSINE-5'-DIPHOSPHATE, PHOSPHATE ION | | 著者 | Raw, A.S, Coleman, D.E, Gilman, A.G, Sprang, S.R. | | 登録日 | 1997-08-11 | | 公開日 | 1997-11-12 | | 最終更新日 | 2023-08-02 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Structural and biochemical characterization of the GTPgammaS-, GDP.Pi-, and GDP-bound forms of a GTPase-deficient Gly42 --> Val mutant of Gialpha1.
Biochemistry, 36, 1997
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1AS0
 | | GTP-GAMMA-S BOUND G42V GIA1 | | 分子名称: | 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, GIA1, MAGNESIUM ION, ... | | 著者 | Raw, A.S, Coleman, D.E, Gilman, A.G, Sprang, S.R. | | 登録日 | 1997-08-11 | | 公開日 | 1997-11-12 | | 最終更新日 | 2023-08-02 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structural and biochemical characterization of the GTPgammaS-, GDP.Pi-, and GDP-bound forms of a GTPase-deficient Gly42 --> Val mutant of Gialpha1.
Biochemistry, 36, 1997
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1AZS
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1AS3
 | | GDP BOUND G42V GIA1 | | 分子名称: | GIA1, GUANOSINE-5'-DIPHOSPHATE, SULFATE ION | | 著者 | Raw, A.S, Coleman, D.E, Gilman, A.G, Sprang, S.R. | | 登録日 | 1997-08-11 | | 公開日 | 1997-11-12 | | 最終更新日 | 2023-08-02 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structural and biochemical characterization of the GTPgammaS-, GDP.Pi-, and GDP-bound forms of a GTPase-deficient Gly42 --> Val mutant of Gialpha1.
Biochemistry, 36, 1997
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1NCF
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6MFA
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6MSV
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6MM1
 | | Structure of the cysteine-rich region from human EHMT2 | | 分子名称: | Histone-lysine N-methyltransferase EHMT2, ZINC ION | | 著者 | Kerchner, K.M, Mou, T.C, Sprang, S.R, Briknarova, K. | | 登録日 | 2018-09-28 | | 公開日 | 2019-10-02 | | 最終更新日 | 2023-05-17 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | The structure of the cysteine-rich region from human histone-lysine N-methyltransferase EHMT2 (G9a).
J Struct Biol X, 5, 2021
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1ANN
 | | ANNEXIN IV | | 分子名称: | ANNEXIN IV, CALCIUM ION | | 著者 | Sutton, R.B, Sprang, S.R. | | 登録日 | 1995-09-21 | | 公開日 | 1996-01-29 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Three Dimensional Structure of Annexin IV
Annexins: Molecular Structure to Cellular Function, 1996
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1A25
 | | C2 DOMAIN FROM PROTEIN KINASE C (BETA) | | 分子名称: | CALCIUM ION, O-PHOSPHOETHANOLAMINE, PROTEIN KINASE C (BETA) | | 著者 | Sutton, R.B, Sprang, S.R. | | 登録日 | 1998-01-16 | | 公開日 | 1998-05-06 | | 最終更新日 | 2023-08-02 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Structure of the protein kinase Cbeta phospholipid-binding C2 domain complexed with Ca2+.
Structure, 6, 1998
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1AGR
 | | COMPLEX OF ALF4-ACTIVATED GI-ALPHA-1 WITH RGS4 | | 分子名称: | CITRIC ACID, GUANINE NUCLEOTIDE-BINDING PROTEIN G(I), GUANOSINE-5'-DIPHOSPHATE, ... | | 著者 | Tesmer, J.J.G, Sprang, S.R. | | 登録日 | 1997-03-25 | | 公開日 | 1997-06-16 | | 最終更新日 | 2023-08-02 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Structure of RGS4 bound to AlF4--activated G(i alpha1): stabilization of the transition state for GTP hydrolysis.
Cell(Cambridge,Mass.), 89, 1997
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1AZT
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5I56
 | | Agonist-bound GluN1/GluN2A agonist binding domains with TCN201 | | 分子名称: | GLUTAMIC ACID, GLYCINE, Glutamate receptor ionotropic, ... | | 著者 | Mou, T.-C, Sprang, S.R, Hansen, K.B. | | 登録日 | 2016-02-14 | | 公開日 | 2016-09-07 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.28 Å) | | 主引用文献 | Structural Basis for Negative Allosteric Modulation of GluN2A-Containing NMDA Receptors.
Neuron, 91, 2016
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4MU8
 | | Crystal structure of an oxidized form of yeast iso-1-cytochrome c at pH 8.8 | | 分子名称: | Cytochrome c iso-1, GLYCEROL, HEME C, ... | | 著者 | McClelland, L.J, Mou, T.-C, Jeakins-Cooley, M.E, Sprang, S.R, Bowler, B.E. | | 登録日 | 2013-09-20 | | 公開日 | 2014-06-04 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | | 主引用文献 | Structure of a mitochondrial cytochrome c conformer competent for peroxidase activity.
Proc.Natl.Acad.Sci.USA, 111, 2014
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1TNF
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1XHM
 | | The Crystal Structure of a Biologically Active Peptide (SIGK) Bound to a G Protein Beta:Gamma Heterodimer | | 分子名称: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) gamma-2 subunit, Guanine nucleotide-binding protein G(I)/G(S)/G(T) beta subunit 1, SIGK Peptide | | 著者 | Davis, T.L, Bonacci, T.M, Smrcka, A.V, Sprang, S.R. | | 登録日 | 2004-09-20 | | 公開日 | 2005-08-09 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Structural and Molecular Characterization of a Preferred Protein Interaction Surface on G Protein betagamma Subunits.
Biochemistry, 44, 2005
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6NMG
 | | Crystal Structure of Rat Ric-8A G alpha binding domain | | 分子名称: | Resistance to inhibitors of cholinesterase 8 homolog A (C. elegans), SULFATE ION | | 著者 | Zeng, B, Mou, T.C, Sprang, S.R. | | 登録日 | 2019-01-10 | | 公開日 | 2019-06-26 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structure, Function, and Dynamics of the G alpha Binding Domain of Ric-8A.
Structure, 27, 2019
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