4I0N
 
 | | Pore forming protein | | 分子名称: | 1,2-ETHANEDIOL, MAGNESIUM ION, Necrotic enteritis toxin B | | 著者 | Yan, X, Porter, C.J, Hardy, S.P, Steer, D, Smith, A.I, Quinset, N, Hughes, V, Cheung, J.K, Keyburn, A.L, Kaldhusdal, M, Moore, R.J, Bannam, T.L, Whisstock, J.C, Rood, J.I. | | 登録日 | 2012-11-16 | | 公開日 | 2013-03-20 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structural and functional analysis of the pore-forming toxin NetB from Clostridium perfringens
MBio, 4, 2013
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4KKD
 | | The X-ray crystal structure of Mannose-binding lectin-associated serine proteinase-3 reveals the structural basis for enzyme inactivity associated with the 3MC syndrome | | 分子名称: | IMIDAZOLE, Mannan-binding lectin serine protease 1 | | 著者 | Yongqing, T, Wilmann, P.G, Reeve, S.B, Coetzer, T.H, Smith, A.I, Whisstock, J.C, Pike, R.N, Wijeyewickrema, L.C. | | 登録日 | 2013-05-05 | | 公開日 | 2013-07-03 | | 最終更新日 | 2013-08-21 | | 実験手法 | X-RAY DIFFRACTION (2.5991 Å) | | 主引用文献 | The X-ray Crystal Structure of Mannose-binding Lectin-associated Serine Proteinase-3 Reveals the Structural Basis for Enzyme Inactivity Associated with the Carnevale, Mingarelli, Malpuech, and Michels (3MC) Syndrome.
J.Biol.Chem., 288, 2013
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2QP2
 | | Structure of a MACPF/perforin-like protein | | 分子名称: | CALCIUM ION, Unknown protein | | 著者 | Rosado, C.J, Buckle, A.M, Law, R.H.P, Butcher, R.E, Kan, W.T, Bird, C.H, Ung, K, Browne, K.A, Baran, K, Bashtannyk-Puhalovich, T.A, Faux, N.G, Wong, W, Porter, C.J, Pike, R.N, Ellisdon, A.M, Pearce, M.C, Bottomley, S.P, Emsley, J, Smith, A.I, Rossjohn, J, Hartland, E.L, Voskoboinik, I, Trapani, J.A, Bird, P.I, Dunstone, M.A, Whisstock, J.C. | | 登録日 | 2007-07-22 | | 公開日 | 2007-09-04 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | A common fold mediates vertebrate defense and bacterial attack
Science, 317, 2007
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2DUT
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3TI9
 | | Crystal structure of the basic protease BprB from the ovine footrot pathogen, Dichelobacter nodosus | | 分子名称: | CALCIUM ION, CHLORIDE ION, GLYCEROL, ... | | 著者 | Wong, W, Whisstock, J.C, Porter, C.J. | | 登録日 | 2011-08-20 | | 公開日 | 2011-10-19 | | 最終更新日 | 2018-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | S1 Pocket of a Bacterially Derived Subtilisin-like Protease Underpins Effective Tissue Destruction.
J.Biol.Chem., 286, 2011
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3TI7
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3LPA
 | | Crystal structure of a subtilisin-like protease | | 分子名称: | Acidic extracellular subtilisin-like protease AprV2, CALCIUM ION | | 著者 | Porter, C.J, Wong, W, Whisstock, J.C, Rood, J.I, Kennan, R.M. | | 登録日 | 2010-02-05 | | 公開日 | 2010-12-08 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | The Subtilisin-Like Protease AprV2 Is Required for Virulence and Uses a Novel Disulphide-Tethered Exosite to Bind Substrates
Plos Pathog., 6, 2010
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3LPD
 | | Crystal structure of a subtilisin-like protease | | 分子名称: | Acidic extracellular subtilisin-like protease AprV2, CALCIUM ION | | 著者 | Porter, C.J, Wong, W, Whisstock, J.C, Rood, J.I, Kennan, R.M. | | 登録日 | 2010-02-05 | | 公開日 | 2010-12-08 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | The Subtilisin-Like Protease AprV2 Is Required for Virulence and Uses a Novel Disulphide-Tethered Exosite to Bind Substrates
Plos Pathog., 6, 2010
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2H4R
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2H4Q
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2H4P
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3LPC
 | | Crystal structure of a subtilisin-like protease | | 分子名称: | ACETATE ION, AprB2, CALCIUM ION, ... | | 著者 | Porter, C.J, Wong, W, Whisstock, J.C, Rood, J.I, Kennan, R.M. | | 登録日 | 2010-02-05 | | 公開日 | 2010-12-08 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | The Subtilisin-Like Protease AprV2 Is Required for Virulence and Uses a Novel Disulphide-Tethered Exosite to Bind Substrates
Plos Pathog., 6, 2010
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2OKK
 | | The X-ray crystal structure of the 65kDa isoform of Glutamic Acid Decarboxylase (GAD65) | | 分子名称: | GAMMA-AMINO-BUTANOIC ACID, GLYCEROL, Glutamate decarboxylase 2 | | 著者 | Buckle, A.M, Fenalti, G, Law, R.H.P, Whisstock, J.C. | | 登録日 | 2007-01-17 | | 公開日 | 2007-03-27 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | GABA production by glutamic acid decarboxylase is regulated by a dynamic catalytic loop.
Nat.Struct.Mol.Biol., 14, 2007
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2OKJ
 | | The X-ray crystal structure of the 67kDa isoform of Glutamic Acid Decarboxylase (GAD67) | | 分子名称: | 4-[({3-HYDROXY-2-METHYL-5-[(PHOSPHONOOXY)METHYL]PYRIDIN-4-YL}METHYL)AMINO]BUTANOIC ACID, GAMMA-AMINO-BUTANOIC ACID, Glutamate decarboxylase 1 | | 著者 | Buckle, A.M, Fenalti, G, Law, R.H.P, Whisstock, J.C. | | 登録日 | 2007-01-17 | | 公開日 | 2007-03-27 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | GABA production by glutamic acid decarboxylase is regulated by a dynamic catalytic loop.
Nat.Struct.Mol.Biol., 14, 2007
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2PEE
 | | Crystal Structure of a Thermophilic Serpin, Tengpin, in the Native State | | 分子名称: | GLYCEROL, SULFATE ION, Serine protease inhibitor | | 著者 | Zhang, Q.W, Buckle, A.M, Whisstock, J.C. | | 登録日 | 2007-04-02 | | 公開日 | 2007-06-19 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | The N terminus of the serpin, tengpin, functions to trap the metastable native state.
Embo Rep., 8, 2007
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2PEF
 | | Crystal Structure of a Thermophilic Serpin, Tengpin, in the Latent State | | 分子名称: | Serine protease inhibitor | | 著者 | Zhang, Q.W, Buckle, A.M, Whisstock, J.C. | | 登録日 | 2007-04-03 | | 公開日 | 2007-06-19 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | The N terminus of the serpin, tengpin, functions to trap the metastable native state.
Embo Rep., 8, 2007
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4DUR
 | | The X-ray Crystal Structure of Full-Length type II Human Plasminogen | | 分子名称: | ACETATE ION, BICARBONATE ION, CHLORIDE ION, ... | | 著者 | Law, R.H.P, Caradoc-Davies, T, Whisstock, J.C. | | 登録日 | 2012-02-22 | | 公開日 | 2012-03-28 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | | 主引用文献 | The X-ray crystal structure of full-length human plasminogen
Cell Rep, 1, 2012
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4DUU
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